{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T16:36:00Z","timestamp":1781368560782,"version":"3.54.1"},"reference-count":13,"publisher":"Inter-Research Science Center","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dis. Aquat. Org."],"published-print":{"date-parts":[[2020,2,13]]},"abstract":"<jats:p>One spotted pike-characin <jats:italic>Boulengerella maculata<\/jats:italic>, managed in a public display aquarium for 7 yr, developed a small unilateral pink growth associated with the right nare. The growth eventually extended through both nares after 5 mo. <jats:italic>B. maculata<\/jats:italic> is a species of piscivorous fish that relies on visual acuity when hunting prey. The rapidly-growing bilateral tumor would have impeded vision if left untreated. The fish was managed for over 10 mo using only surgical debulking, topical liquid nitrogen, and occasional nonsteroidal anti-inflammatory medications as needed to reduce tumor size and restore sight. Diagnosis proved challenging due to superimposed inflammation, neoplasm cellular inconsistencies, and a lack of proven immunohistochemical stains or other diagnostic stains. Using tumor location and appearance, histopathology, advanced imaging, electron microscopy, special staining, and immunohistochemistry, the ultimate diagnosis confirmed olfactory neuroblastoma, or esthesioneuroblastoma. Although long-term prognosis is poor, hunting strategy of the affected species may dictate quality of life, as appetite, body condition, and behavior remained largely unchanged in this animal until time of euthanasia.<\/jats:p>","DOI":"10.3354\/dao03446","type":"journal-article","created":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T05:06:29Z","timestamp":1578287189000},"page":"29-33","source":"Crossref","is-referenced-by-count":3,"title":["Rare neural crest tumor in teleost species: olfactory neuroblastoma in a spotted pike-characin Boulengerella maculata"],"prefix":"10.3354","volume":"138","author":[{"given":"AC","family":"Gould","sequence":"first","affiliation":[{"name":"Vancouver Aquarium and Marine Science Centre, Vancouver, BC V6G 3E2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Haulena","sequence":"additional","affiliation":[{"name":"Vancouver Aquarium and Marine Science Centre, Vancouver, BC V6G 3E2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Pawlik","sequence":"additional","affiliation":[{"name":"Animal Health Center, Abbotsford, BC V3G 2M3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"LePage","sequence":"additional","affiliation":[{"name":"University of Guelph Animal Health Laboratory, Guelph, ON N1G 2W1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Mareschal","sequence":"additional","affiliation":[{"name":"Canada West Veterinary Specialists, Vancouver, BC V5M 4Y3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MRM","family":"Manalang","sequence":"additional","affiliation":[{"name":"Vancouver Aquarium and Marine Science Centre, Vancouver, BC V6G 3E2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Snyman","sequence":"additional","affiliation":[{"name":"Animal Health Center, Abbotsford, BC V3G 2M3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1913","reference":[{"key":"Ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2011.06.002"},{"key":"Ref2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-0019"},{"key":"Ref3","unstructured":"Ishikawa T, Masahito P, Takayama S (1978) Olfactory neuroepithelioma in a domestic carp (Cyprinus carpio). 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