{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:51:13Z","timestamp":1790628673266,"version":"4.1.0"},"reference-count":22,"publisher":"Inter-Research Science Center","license":[{"start":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T00:00:00Z","timestamp":1605744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.int-res.com\/journals\/terms-of-use\/"}],"content-domain":{"domain":["int-res.com"],"crossmark-restriction":false},"short-container-title":["Dis. Aquat. Org."],"published-print":{"date-parts":[[2020,11,19]]},"abstract":"<jats:p>Pinniped tuberculosis, commonly caused by <jats:italic>Mycobacterium pinnipedii<\/jats:italic>, is a zoonotic disease reported in free-living and captive otariid species of the southern hemisphere. Currently, data concerning pinniped tuberculosis in South America are scarce, reinforcing the need for further studies of the disease in free-ranging pinnipeds. In this study, we investigated the presence of tuberculosis in South American sea lions <jats:italic>Otaria flavescens<\/jats:italic> (SASLs) stranded along the Chubut coastline (Argentina). Necropsies were performed in 9 SASLs, and tissue samples were collected for histopathology, bacteriology, and molecular diagnosis. Four SASLs showed enlarged tracheobronchial lymph nodes (TBLNs) with multifocal to coalescing granulomas. In these animals, a direct IS<jats:italic>6110-<\/jats:italic>PCR amplification confirmed the presence of a <jats:italic>Mycobacterium tuberculosis<\/jats:italic> complex member in TBLNs (n = 4) and lungs (n = 2), but the agent could not be further identified. In one SASL, <jats:italic>Mycobacterium murale<\/jats:italic> was isolated from lungs without lesions. This study confirms the presence of tuberculosis in SASLs from Chubut, where tourist activities promote close interaction with the animals, generating a potential risk to human health. Further research is currently focusing on addressing the prevalence of tuberculosis in wild SASLs, to assess the risk for public health and develop management strategies to avoid human infection.<\/jats:p>","DOI":"10.3354\/dao03520","type":"journal-article","created":{"date-parts":[[2020,8,6]],"date-time":"2020-08-06T08:15:29Z","timestamp":1596701729000},"page":"33-40","update-policy":"https:\/\/doi.org\/10.3354\/policy","source":"Crossref","is-referenced-by-count":7,"title":["Tuberculosis in wild South American sea lions Otaria flavescens stranded in Chubut, Argentina"],"prefix":"10.3354","volume":"142","author":[{"given":"C","family":"Fiorito","sequence":"first","affiliation":[{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas, Centro para el Estudio de Sistemas Marinos (CESIMAR-CONICET), U9120, Chubut, Argentina"},{"name":"Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Instituto de Investigaci\u00f3n y Tecnolog\u00eda en Reproducci\u00f3n Animal (INITRA), C\u00e1tedra de Histolog\u00eda y Embriolog\u00eda, C1427CWO, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Marfil","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires. Facultad de Ciencias Veterinarias, C\u00e1tedra de Enfermedades Infecciosas, C1427CWO, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Falzoni","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires. Facultad de Ciencias Veterinarias, C\u00e1tedra de Enfermedades Infecciosas, C1427CWO, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Mart\u00ednez Vivot","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires. Facultad de Ciencias Veterinarias, C\u00e1tedra de Enfermedades Infecciosas, C1427CWO, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Zum\u00e1rraga","sequence":"additional","affiliation":[{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas, Instituto de Agrobiotecnolog\u00eda y Biolog\u00eda Molecular, Instituto Nacional de Tecnolog\u00eda Agropecuaria (IABIMO, INTA-CONICET), C1033AAE, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Lombardo","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. 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Facultad de Ciencias Veterinarias, C\u00e1tedra de Enfermedades Infecciosas, C1427CWO, Buenos Aires, Argentina"},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), C1425FQB, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1913","reference":[{"key":"Ref1","doi-asserted-by":"publisher","DOI":"10.5772\/54214"},{"key":"Ref2","doi-asserted-by":"publisher","DOI":"10.20506\/rst.15.3.963"},{"key":"Ref3","doi-asserted-by":"publisher","DOI":"10.1638\/2012-0110R.1"},{"key":"Ref4","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.02401-0"},{"key":"Ref5","doi-asserted-by":"crossref","unstructured":"Dans SL, Crespo EA, Coscarella MA (2017) Wildlife tourism: underwater behavioral responses of South American sea lions to swimmers. 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