{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:21:27Z","timestamp":1785417687560,"version":"3.56.0"},"reference-count":45,"publisher":"Inter-Research Science Center","license":[{"start":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T00:00:00Z","timestamp":1626307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.int-res.com\/journals\/terms-of-use\/"}],"content-domain":{"domain":["int-res.com"],"crossmark-restriction":false},"short-container-title":["Dis. Aquat. Org."],"published-print":{"date-parts":[[2021,7,15]]},"abstract":"<jats:p>Microbiology records for 1127 cetaceans stranded on English and Welsh beaches and examined at the Institute of Zoology between 1990 and 2019 were reviewed to identify cases of <jats:italic>Erysipelothrix rhusiopathiae<\/jats:italic>, an uncommon but potentially fatal zoonotic pathogen. Once cases were identified, prevalence was calculated, corresponding postmortem reports were reviewed, common gross and histopathological findings were identified, and antibiotic susceptibilities were determined. Overall prevalence for <jats:italic>E. rhusiopathiae<\/jats:italic> was 0.62% (7\/1127; 95% CI: 0.30-1.28%). It was isolated from 3 bottlenose dolphins <jats:italic>Tursiops truncatus<\/jats:italic>, 3 harbor porpoises <jats:italic>Phocoena phocoena<\/jats:italic>, and 1 short-beaked common dolphin <jats:italic>Delphinus delphis<\/jats:italic>, with a prevalence of 21.4% (3\/14; 95% CI: 7.6-47.9%), 0.39% (3\/779; 95% CI: 0.13-1.13%), and 0.47% (1\/212; 95% CI: 0.08-2.62%) for each species, respectively. <jats:italic>E. rhusiopathiae<\/jats:italic> resulted in septicemia in all cases from which it was isolated. Gross necropsy findings included pulmonary edema (5\/7), hemorrhage (5\/7) and\/or congestion of various organs (4\/7), and serosanguineous effusion (3\/7; pericardial: 3\/7, pleural: 2\/6, abdominal: 2\/6). Congestion (5\/5), bacterial emboli (4\/5), and hemorrhage (4\/5) were commonly observed on histopathology, and acute renal tubular injury (2\/5) and pulmonary edema (2\/5) were occasionally observed. Routine bacterial cultures were vital in identifying <jats:italic>E. rhusiopathiae<\/jats:italic>, since gross lesions were often subtle and nonspecific. The liver, kidney, and brain were key organs from which <jats:italic>E. rhusiopathiae<\/jats:italic> was consistently isolated. Antibiotic resistance was uncommon and was only observed for amikacin and trimethoprim sulfonamide. Penicillins were consistently effective, along with fluoroquinolones, macrolides, clindamycin, cephalexin, and oxytetracycline.<\/jats:p>","DOI":"10.3354\/dao03609","type":"journal-article","created":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T07:30:44Z","timestamp":1620631844000},"page":"173-184","update-policy":"https:\/\/doi.org\/10.3354\/policy","source":"Crossref","is-referenced-by-count":13,"title":["Systemic Erysipelothrix rhusiopathiae in seven free-ranging delphinids stranded in England and Wales"],"prefix":"10.3354","volume":"145","author":[{"given":"ME","family":"Ceccolini","sequence":"first","affiliation":[{"name":"Zoological Society of London, Regent's Park, Outer Circle, London NW1 4RY, UK"},{"name":"Royal Veterinary College, Hatfield AL9 7TA, UK"},{"name":"Sedgwick County Zoo, 5555 Zoo Blvd., Wichita, KS 67212, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Wessels","sequence":"additional","affiliation":[{"name":"Finn Pathologists, Harleston IP20 9EB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SK","family":"Macgregor","sequence":"additional","affiliation":[{"name":"Zoological Society of London, Regent's Park, Outer Circle, London NW1 4RY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Deaville","sequence":"additional","affiliation":[{"name":"Institute of Zoology, Zoological Society of London, London NW1 4RY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Perkins","sequence":"additional","affiliation":[{"name":"Institute of Zoology, Zoological Society of London, London NW1 4RY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PD","family":"Jepson","sequence":"additional","affiliation":[{"name":"Institute of Zoology, Zoological Society of London, London NW1 4RY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SK","family":"John","sequence":"additional","affiliation":[{"name":"Institute of Zoology, Zoological Society of London, London NW1 4RY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Guthrie","sequence":"additional","affiliation":[{"name":"Zoological Society of London, Regent's Park, Outer Circle, London NW1 4RY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1913","reference":[{"key":"Ref1","unstructured":"Bell SM, Carter JN, Hanrahan IW, Nguyen TT (2016) Antibiotic susceptibility testing by the CDS method: a manual for medical and veterinary laboratories, 8th edn. 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