{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T16:32:28Z","timestamp":1771259548364,"version":"3.50.1"},"reference-count":22,"publisher":"Inter-Research Science Center","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.int-res.com\/journals\/terms-of-use\/"}],"content-domain":{"domain":["int-res.com"],"crossmark-restriction":false},"short-container-title":["Dis. Aquat. Org."],"published-print":{"date-parts":[[2023,9,28]]},"abstract":"<jats:p>Gastritis and gastric ulcers are well-recognized conditions in cetaceans; bacteria of the genus <jats:italic>Helicobacter<\/jats:italic> are considered the primary cause of these diseases. Dolphins have been shown to be susceptible to infection by at least 2 gastric species of <jats:italic>Helicobacter<\/jats:italic>, <jats:italic>H. cetorum<\/jats:italic> and <jats:italic>H. delphinicola<\/jats:italic>, both of which are closely related to the human pathogen <jats:italic>H. pylori<\/jats:italic>. In the present study, we evaluated the carriage rate and relationship to gastric disease of <jats:italic>H. cetorum<\/jats:italic> and <jats:italic>H. delphinicola<\/jats:italic>, based on a study population of 82 dolphins maintained at 21 facilities in Japan. Of these 82 dolphins, 79 (96.3%) and 45 (54.9%) were positive for <jats:italic>H. cetorum<\/jats:italic> and <jats:italic>H. delphinicola<\/jats:italic>, respectively; <jats:italic>H. delphinicola<\/jats:italic> infection was significantly associated with chronic gastric diseases (odds rate: 5.9; 95% CI: 2.1-16.9), but no such association was detected for <jats:italic>H. cetorum.<\/jats:italic> Of the 21 facilities, 20 (95%) and 11 (55%) housed <jats:italic>H. cetorum<\/jats:italic>- and <jats:italic>H. delphinicola<\/jats:italic>-positive dolphins, respectively, and our study suggested that the transmission between dolphins occurs quickly within pools. These findings indicate that methods will need to be established to prevent the transmission of <jats:italic>Helicobacter<\/jats:italic> infections within facilities housing dolphins.<\/jats:p>","DOI":"10.3354\/dao03751","type":"journal-article","created":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T15:34:51Z","timestamp":1691595291000},"page":"187-192","update-policy":"https:\/\/doi.org\/10.3354\/policy","source":"Crossref","is-referenced-by-count":6,"title":["Helicobacter delphinicola infection and the risk of gastric disease in common bottlenose dolphin"],"prefix":"10.3354","volume":"155","author":[{"given":"T","family":"Segawa","sequence":"first","affiliation":[{"name":"Cetacean Research Center, Graduate School of Bioresources, Mie University, 1577 Kurimamachiya, Tsu, Mie 514-8507, Japan"},{"name":"Laboratory of Preventive Veterinary Medicine and Animal Health, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y","family":"Ohno","sequence":"additional","affiliation":[{"name":"Port of Nagoya Public Aquarium, 1-3 Minato-machi, Minato-ku, Nagoya 455-0033, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Kurita","sequence":"additional","affiliation":[{"name":"Port of Nagoya Public Aquarium, 1-3 Minato-machi, Minato-ku, Nagoya 455-0033, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Ishibashi","sequence":"additional","affiliation":[{"name":"Japan Aquarium Association, 1-7-1 Yurakucho, Chiyoda-ku, Tokyo 100-0006, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Yoshioka","sequence":"additional","affiliation":[{"name":"Cetacean Research Center, Graduate School of Bioresources, Mie University, 1577 Kurimamachiya, Tsu, Mie 514-8507, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1913","reference":[{"key":"Ref1","unstructured":"Bauman S (2020) Analysis of the antibiotic susceptibility and culture conditions of Helicobacter cetorum, a seaborne gastric pathogen. PhD Thesis, Florida Southern College, Lakeland, FL"},{"key":"Ref2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10516"},{"key":"Ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2018.04.014"},{"key":"Ref4","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.12.3165-3170.1996"},{"key":"Ref5","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq378"},{"key":"Ref6","doi-asserted-by":"publisher","DOI":"10.3390\/toxins8060173"},{"key":"Ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2007.00526.x"},{"key":"Ref8","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.12.4536-4543.2002"},{"key":"Ref9","unstructured":"Henry GA, Long PH, Burns JL, Charbonneau DL (1987) Gastric spirillosis in beagles. 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CRC Press, New York, NY, p 367-388"},{"key":"Ref21","doi-asserted-by":"publisher","DOI":"10.7880\/abas.0211229a"},{"key":"Ref22","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12217"}],"container-title":["Diseases of Aquatic Organisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.int-res.com\/articles\/dao2023\/155\/d155p187.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.int-res.com\/articles\/dao2023\/155\/d155p187.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T10:49:52Z","timestamp":1695898192000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.int-res.com\/abstracts\/dao\/v155\/p187-192\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,28]]},"references-count":22,"URL":"https:\/\/doi.org\/10.3354\/dao03751","relation":{},"ISSN":["0177-5103","1616-1580"],"issn-type":[{"value":"0177-5103","type":"print"},{"value":"1616-1580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,28]]}}}