{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:11:29Z","timestamp":1790644289187,"version":"4.1.0"},"reference-count":57,"publisher":"Inter-Research Science Center","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["int-res.com"],"crossmark-restriction":false},"short-container-title":["Dis. Aquat. Org."],"abstract":"<jats:p>Infections by <jats:italic>Erysipelothrix rhusiopathiae<\/jats:italic> occur in domestic animals and cause the disease known as \u2018erysipelas\u2019. The ubiquity of <jats:italic>Erysipelothrix<\/jats:italic> spp. makes infection possible in a wide range of vertebrates and invertebrates. Cetaceans are highly susceptible to erysipelas, especially those under human care. The number of cases documented in wild cetaceans is low, the pathogenesis is incompletely understood, and the full spectrum of lesions is not well defined. The possible serotypes and species of the genus that can cause disease are unknown. In October 2022, a common bottlenose dolphin <jats:italic>Tursiops truncatus<\/jats:italic> stranded in Vilassar de Mar (Catalonia) showing skin lesions consistent with \u2018diamond skin disease\u2019, a characteristic lesion of erysipelas shared by swine and cetaceans. Necropsy was performed following standardized procedures, and multiple samples were taken for histopathology and bacteriology. <jats:italic>Erysipelothrix<\/jats:italic> sp. grew in pure culture in many tissue samples. Genetic characterization by multi-locus sequence analysis identified the species as <jats:italic>E.<\/jats:italic> <jats:italic>rhusiopathiae<\/jats:italic>. Histologically, the main lesions were an intense suppurative vasculitis of leptomeningeal arteries and veins with abundant intramural Gram-positive bacilli and meningeal hemorrhages. Meningeal lesions were considered the cause of death. The affected skin showed moderate suppurative dermatitis. Herein we document a case of erysipelas in a Mediterranean common bottlenose dolphin with unusual lesions in the leptomeningeal vessels and marked skin tropism. To our knowledge, this is the first case of severe brain involvement in erysipelas in a cetacean. We also provide a review of available cases in wild cetaceans, to highlight the characteristics of the disease and improve future diagnosis.<\/jats:p>","DOI":"10.3354\/dao03770","type":"journal-article","created":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T10:22:48Z","timestamp":1702462968000},"page":"31-43","update-policy":"https:\/\/doi.org\/10.3354\/policy","source":"Crossref","is-referenced-by-count":7,"title":["Erysipelas with preferential brain and skin involvement in a Mediterranean bottlenose dolphin Tursiops truncatus"],"prefix":"10.3354","volume":"157","author":[{"given":"L","family":"Martino","sequence":"first","affiliation":[{"name":"Servei de Diagn\u00f2stic de Patologia Veterin\u00e0ria, Universitat Aut\u00f2noma de Barcelona, 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Serrano","sequence":"additional","affiliation":[{"name":"Servei de Diagn\u00f2stic de Patologia Veterin\u00e0ria, Universitat Aut\u00f2noma de Barcelona, 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Alomar","sequence":"additional","affiliation":[{"name":"Servei de Diagn\u00f2stic de Patologia Veterin\u00e0ria, Universitat Aut\u00f2noma de Barcelona, 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Facultat de Veterin\u00e0ria de Barcelona, Universitat Aut\u00f2noma de Barcelona, 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Aragon","sequence":"additional","affiliation":[{"name":"Unitat Mixta d\u2019Investigaci\u00f3 IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"},{"name":"IRTA Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Cobos","sequence":"additional","affiliation":[{"name":"Unitat Mixta d\u2019Investigaci\u00f3 IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"},{"name":"IRTA Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"},{"name":"Departament de Sanitat i Anatomia Animals, Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ML","family":"Abarca","sequence":"additional","affiliation":[{"name":"Departament de Sanitat i Anatomia Animals, Universitat Aut\u00f2noma de Barcelona, 08193 Bellaterra, Spain"},{"name":"Veterinary Mycology Group, Facultat de Veterin\u00e0ria, Universitat Aut\u00f2noma de Barcelona, 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z","family":"Yazdi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Soto","sequence":"additional","affiliation":[{"name":"Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Domingo","sequence":"additional","affiliation":[{"name":"Servei de Diagn\u00f2stic de Patologia Veterin\u00e0ria, Universitat Aut\u00f2noma de Barcelona, 08193 Bellaterra, Spain"},{"name":"Unitat Mixta d\u2019Investigaci\u00f3 IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"},{"name":"IRTA Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"},{"name":"Departament de Sanitat i Anatomia Animals, Universitat Aut\u00f2noma de Barcelona (UAB), 08193 Bellaterra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1913","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"key":"Ref1","unstructured":"Aslani MR, Ebrahimi Kahrisangi A, Baghban F, Kazemi A, Heidari M, Salehi N (2015) Endocarditis associated with Erysipelothrix rhusiopathiae in a fat-tailed ram. Iran J Vet Res 16:310-\u2060312"},{"key":"Ref2","doi-asserted-by":"publisher","DOI":"10.1177\/104063871102300126"},{"key":"Ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S0043933913000822"},{"key":"Ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-020-02546-6"},{"key":"Ref5","doi-asserted-by":"publisher","DOI":"10.3354\/dao03609"},{"key":"Ref6","unstructured":"Chastel C, Masure O, Balouet G, Laban P, Lucas A (1975) L\u2019\u00e9tudiant, le c\u00e9tac\u00e9 et le rouget. Une petite \u00e9pid\u00e9mie d\u2019\u00e9rysip\u00e9lo\u00efde apr\u00e8s d\u00e9pe\u00e7age d\u2019un globic\u00e9phale. Nouv Presse Med 4:1803-\u20601805"},{"key":"Ref7","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-5317-7.00002-3"},{"key":"Ref8","doi-asserted-by":"publisher","DOI":"10.3354\/dao03550"},{"key":"Ref9","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.27789"},{"key":"Ref10","doi-asserted-by":"publisher","DOI":"10.3354\/dao02900"},{"key":"Ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2018.03.020"},{"key":"Ref12","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.005454"},{"key":"Ref13","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.66.5.2066-2070.2000"},{"key":"Ref14","doi-asserted-by":"publisher","DOI":"10.3354\/dao03041"},{"key":"Ref15","doi-asserted-by":"publisher","DOI":"10.3390\/d15040569"},{"key":"Ref16","unstructured":"Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT. Nucleic Acids Symp Ser 41:95-\u206098"},{"key":"Ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2013.03.013"},{"key":"Ref18","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2022.2140614"},{"key":"Ref19","doi-asserted-by":"publisher","DOI":"10.3201\/eid2904.221698"},{"key":"Ref20","unstructured":"Joblon MJ, Pokras MA, Morse B, Harry CT and others (2014) Body condition scoring system for delphinids based on short-beaked common dolphins (Delphinus delphis). J Mar Anim Ecol 7:5-\u206013"},{"key":"Ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2010.10.009"},{"key":"Ref22","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.47199-0"},{"key":"Ref23","unstructured":"Kinsel MJ, Boehm JR, Harris B, Murnane RD (1997) Fatal Erysipelothrix rhusiopathiae septicemia in a captive Pacific white-sided dolphin (Lagenorhyncus [sic] obliquidens). J Zoo Wildl Med 28:494-\u2060497"},{"key":"Ref24","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.3.434"},{"key":"Ref25","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msy096"},{"key":"Ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1135(01)00311-X"},{"key":"Ref27","unstructured":"Lane D (1991) 16S\/23S rRNA sequencing. In: Stackebrandt E, Goodfellow M (eds) Nucleic acid techniques in bacterial systematics. John Wiley & Sons, New York, NY, p 115-\u2060175"},{"key":"Ref28","unstructured":"Lara-P\u00e9rez S, Valladares-Carranza BB, Vel\u00e1zquez-Ordo\u00f1ez V, Ortega-Santana C and others (2015) Erysipelothrix rhusiopathiae en sistema nervioso de un ovino. Reporte cl\u00edinico patol\u00f3gico. Rev Electr\u00f3n Vet 16:1-\u20608"},{"key":"Ref29","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.774836"},{"key":"Ref30","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-020-2250-9"},{"key":"Ref31","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-84966-4"},{"key":"Ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2019.04.003"},{"key":"Ref33","doi-asserted-by":"publisher","DOI":"10.3354\/dao02412"},{"key":"Ref34","doi-asserted-by":"publisher","DOI":"10.3390\/ani12030369"},{"key":"Ref35","doi-asserted-by":"publisher","DOI":"10.1128\/mra.00273-22"},{"key":"Ref36","doi-asserted-by":"publisher","DOI":"10.4081\/idr.2018.7770"},{"key":"Ref37","doi-asserted-by":"publisher","DOI":"10.1002\/9781119350927.ch53"},{"key":"Ref38","doi-asserted-by":"publisher","DOI":"10.1111\/jfd.12673"},{"key":"Ref39","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.003838"},{"key":"Ref40","doi-asserted-by":"crossref","unstructured":"Pugliares KR, Bogomolni A, Touhey KM, Herzig SM, Harry CT, Moore MJ (2007) Marine mammal necropsy: an introductory guide for stranding responders and field biologists. 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Am J Vet Res 39:187-\u2060188"},{"key":"Ref49","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.61.1007"},{"key":"Ref50","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0450.2000.00344.x"},{"key":"Ref51","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a040023"},{"key":"Ref52","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00099-07"},{"key":"Ref53","doi-asserted-by":"publisher","DOI":"10.1002\/9781119350927.ch17"},{"key":"Ref54","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2009.08.012"},{"key":"Ref55","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.13840"},{"key":"Ref56","doi-asserted-by":"publisher","DOI":"10.1128\/jb.173.2.697-703.1991"},{"key":"Ref57","unstructured":"Wood RL (1973) Survival of Erysipelothrix rhusiopathiae in soil under various environmental conditions. 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