{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T11:39:36Z","timestamp":1786621176644,"version":"build-2736575974"},"reference-count":87,"publisher":"Inter-Research Science Center","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.int-res.com\/for-librarians\/reader-subscriber-license"}],"content-domain":{"domain":["int-res.com"],"crossmark-restriction":false},"short-container-title":["Dis. Aquat. Org."],"accepted":{"date-parts":[[2026,5,8]]},"abstract":"<jats:p>\n                    This study investigated the immunomodulatory effects of dietary pineapple peel powder (PPP) supplementation in\n                    <jats:italic>Labeo rohita<\/jats:italic>\n                    fingerlings (15.2 \u00b1 0.3 g) through a 60 d feeding trial followed by a 15 d\n                    <jats:italic>Aeromonas veronii<\/jats:italic>\n                    infection challenge. Processing 1 kg of pineapple fruit generates approximately 30-35% waste, primarily peels, containing bioactive compounds including bromelain enzyme. Using a completely randomized design, 300 fingerlings were distributed into 5 treatment groups in triplicate: Control (0%), T1 (2%), T2 (4%), T3 (6%), and T4 (8%) PPP supplementation. Immunological, haematological, biochemical, and antioxidant parameters were assessed at 0, 15, 30, and 60 d, with bacterial challenge conducted on Day 61 and post-infection (PI) sampling at 7 and 15 d PI. Fish fed 6% PPP (T3) exhibited significantly enhanced immunological parameters, with serum lysozyme activity reaching 185.6 \u00b1 8.4 unit ml\n                    <jats:sup>-1<\/jats:sup>\n                    compared to 112.3 \u00b1 5.7 unit ml\n                    <jats:sup>-1<\/jats:sup>\n                    in control. Significant improvements occurred in haematological indices (red blood cells, white blood cells, hemoglobin, hematocrit), serum proteins (total protein, albumin, globulin), and antioxidant enzyme activities (superoxide dismutase, catalase, glutathione peroxidase). Following\n                    <jats:italic>A. veronii<\/jats:italic>\n                    challenge (1\u00d710\n                    <jats:sup>7<\/jats:sup>\n                    CFU ml\n                    <jats:sup>-1<\/jats:sup>\n                    ; 0.1 ml fish\n                    <jats:sup>-1<\/jats:sup>\n                    ), T3 demonstrated the highest survival rate (82.5 \u00b1 3.4%) compared to control (45.6 \u00b1 2.7%). Growth performance also improved significantly, with specific growth rate (2.84 \u00b1 0.12% vs. 2.15 \u00b1 0.09% d\n                    <jats:sup>-1<\/jats:sup>\n                    ) and feed conversion ratio (1.42 \u00b1 0.06 vs. 1.85 \u00b1 0.08) both enhanced in T3 compared to control. These results demonstrate that 6% PPP supplementation optimally enhances immunophysiological parameters, disease resistance, and growth performance in\n                    <jats:italic>L. rohita<\/jats:italic>\n                    , highlighting its potential as a natural immunostimulant in sustainable aquaculture health management.\n                  <\/jats:p>","DOI":"10.3354\/dao03929","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T07:34:08Z","timestamp":1780558448000},"page":"1-18","update-policy":"https:\/\/doi.org\/10.3354\/policy","source":"Crossref","is-referenced-by-count":0,"title":["Dietary pineapple peel powder supplementation enhances resistance against Aeromonas veronii in Labeo rohita fingerlings"],"prefix":"10.3354","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5888-7650","authenticated-orcid":true,"given":"Chandan","family":"Debnath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1913","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"Ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(84)05016-3"},{"key":"Ref2","unstructured":"APHA (2017) Standard methods for the examination of water and wastewater, 23rd edn. 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