{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:12:26Z","timestamp":1791396746920,"version":"4.3.3"},"reference-count":0,"publisher":"Institute of Physiology of the Czech Academy of Sciences","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Res"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Osteoporosis is a systemic disease of the skeleton, characterized\nby reduction of bone mass and concurrent deterioration of bone\nstructure. Consequently, bones are more fragile, and there is\nincreased risk of fractures. The potential for acquisition of\nmaximum bone mass is influenced by a number of factors.\nAmong those are heredity, sex, nutrition, endocrine factors,\nmechanical influences and some risk factors. The best\ndocumented nutrient for metabolism of bone is calcium. Major\nrole in the pathogenesis of osteoporosis have some micro and\nmacro nutrients, prebiotics, alcohol, alternative diets, starvation\nand anorexia. Meta analysis of 29 randomized trials showed that\nsupplementation with calcium and vitamin D3 reduces risk of\nbone fractures by 24 % and significantly reduces loss of bone\nmass. Osteoporosis has multi factor etiology. Osteoporosis is one\nof diseases which are influenced by nutrition and life style. It is\npreventable by means of adequate nutrition and sufficient\nphysical activity.<\/jats:p>","DOI":"10.33549\/physiolres.931858","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T13:16:48Z","timestamp":1615209408000},"page":"S7-S11","source":"Crossref","is-referenced-by-count":27,"title":["Nutrition as prevention and treatment of osteoporosis"],"prefix":"10.33549","author":[{"given":"M","family":"Str\u00e1nsk\u00fd","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Ry\u0161av\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"19169","published-online":{"date-parts":[[2009]]},"container-title":["Physiological Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T13:16:49Z","timestamp":1615209409000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.biomed.cas.cz\/physiolres\/pdf\/58%20Suppl%201\/58_S7.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":0,"URL":"https:\/\/doi.org\/10.33549\/physiolres.931858","relation":{},"ISSN":["1802-9973","0862-8408"],"issn-type":[{"value":"1802-9973","type":"electronic"},{"value":"0862-8408","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}