{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:59:49Z","timestamp":1791892789818,"version":"4.3.4"},"reference-count":0,"publisher":"Institute of Physiology of the Czech Academy of Sciences","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Res"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Various reactive oxygen species (ROS) may be produced from\nnormal biochemical, essential metabolic processes or from\nexternal sources as exposure to a variety of agents presented in\nthe environment. Lipids, proteins, carbohydrates and DNA are all\ncapable of reacting with ROS and can be implicated in etiology of\nvarious human disorders (rheumatoid arthritis, reperfusion injury,\natherosclerosis, lung diseases etc.). In the organism damage by\nROS is counteracted with natural antioxidants (glutathione\nperoxidases, superoxide dismutases, catalase, glutathione,\nubiquinol, uric acid, and essential minerals) and nutritional\nantioxidants from diet (i.e. vitamins E, C, carotenoids). Possible\nmechanisms of nutritional depletion and side effects of high\nintake are in the article described.<\/jats:p>","DOI":"10.33549\/physiolres.931861","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T13:16:54Z","timestamp":1615209414000},"page":"S13-S17","source":"Crossref","is-referenced-by-count":71,"title":["Antioxidants and vitamins in clinical conditions"],"prefix":"10.33549","author":[{"given":"Z","family":"Zad\u00e1k","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Hy\u0161pler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Tich\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Hronek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Fikrov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Rathousk\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Hrn\u010diarikov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"\u0160t\u011btina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"19169","published-online":{"date-parts":[[2009]]},"container-title":["Physiological Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T13:16:55Z","timestamp":1615209415000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.biomed.cas.cz\/physiolres\/pdf\/58%20Suppl%201\/58_S13.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":0,"URL":"https:\/\/doi.org\/10.33549\/physiolres.931861","relation":{},"ISSN":["1802-9973","0862-8408"],"issn-type":[{"value":"1802-9973","type":"electronic"},{"value":"0862-8408","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}