{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:50:15Z","timestamp":1762098615211},"reference-count":22,"publisher":"Institute of Physiology of the Czech Academy of Sciences","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Res"],"published-print":{"date-parts":[[2011,8,31]]},"abstract":"<jats:p>We performed measurement of mechanical atrioventricular conduction time intervals in human fetuses assessed by Doppler echocardiography and provided reference values. We found that atrioventricular conduction time interval was prolonged with gestational age and decreased with increasing fetal heart rate. No correlation between gestational age and heart rate was found. Using normal limits established by this study, mechanical atrioventricular interval &gt;135 ms in the 20th week and\/or &gt;145 ms in the 26th week of gestation could be suspected of having the first-degree AV block. We compared reference values with fetuses of mothers with anti-SSA Ro\/SSB La autoantibodies, being in risk of isolated congenital heart block development. One of 21 fetuses of mothers with positive autoantibodies was affected by prolonged atrioventricular interval according to the established limits, with sinus rhythm after the birth.<\/jats:p>","DOI":"10.33549\/physiolres.931998","type":"journal-article","created":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T10:34:50Z","timestamp":1580553290000},"page":"611-616","source":"Crossref","is-referenced-by-count":7,"title":["Atrioventricular Conduction Time in Fetuses Assessed by Doppler Echocardiography"],"prefix":"10.33549","author":[{"given":"V.","family":"TOMEK","sequence":"first","affiliation":[{"name":"Kardiocentrum and Cardiovascular Research Centre, University Hospital Motol, Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"JANOU\u0160EK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"REICH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"GIL\u00cdK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"GEBAUER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"\u0160KOVR\u00c1NEK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"19169","published-online":{"date-parts":[[2011,8,17]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"ANDELFINGER G, FOURON JC, SONESSON SE, PROULX F: Reference values for time intervals between atrial and ventricular contractions of the fetal heart measured by two Doppler techniques. Am J Cardiol 88: 1433-1436, 2001.","DOI":"10.1016\/s0002-9149(01)02130-0"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"ASKANASE A, FRIEDMAN D, COPEL J, DISCHE M, DUBIN A, STARC T, KATHOLI MC, BUYON JP: Spectrum and progression of conduction abnormalities in infants born to mothers with anti-SSA\/Ro-SSB\/La antibodies. 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