{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:05:49Z","timestamp":1761609949432},"reference-count":24,"publisher":"Institute of Physiology of the Czech Academy of Sciences","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Res"],"published-print":{"date-parts":[[2017,9,30]]},"abstract":"<jats:p>In women with chronic autoimmune thyroiditis and vitamin D deficiency we have found reference levels of relevant metabolic-hormonal parameters except for parathormone and total calcium. Three months supplementation with vitamin D (4300 IU\/day, cholekalciferol) did not lead to significant changes of investigated hormonal parameters, while the levels of parathormone and calcium reached normal levels. However, a correlation analysis revealed marked changes in mutual relations. First, an inverse correlation of vitamin D with parathormone, insulin secretion (C peptide, insulin) and its efficiency (HOMA IR) disappeared. Relationships of vitamin D to hepatic insulin resistance (insulin\/C peptide), to DHEA (both negative), and to DHEAS\/DHEA ratio (positive) were newly found. Second, a positive correlation of CRP with insulin secretion remained, while its relation to insulin efficiency (HOMA IR, insulin\/ C peptide) was newly observed. Analogical positive correlations appeared also among anti TPO and insulinemia, insulin\/C peptide, HOMA IR, and anti Tg to C peptide. A relationship of the CRP with anti TPO became significant (+). Third, out of glucose metabolism parameters only insulin\/C peptide and glycemia did not correlate with vitamin D during its deficiency, while after supplementation insulin\/ C peptide alone correlated positively with both DHEAS and DHEA, and negatively with vitamin D.<\/jats:p>","DOI":"10.33549\/physiolres.933727","type":"journal-article","created":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T12:12:55Z","timestamp":1580991175000},"page":"S409-S417","source":"Crossref","is-referenced-by-count":6,"title":["Vitamin D Supplementation Changed Relationships, Not Levels of Metabolic-Hormonal Parameters in Autoimmune Thyroiditis"],"prefix":"10.33549","author":[{"given":"K.","family":"VONDRA","sequence":"first","affiliation":[{"name":"Institute of Endocrinology, Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"B\u00cdLEK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"MATUCHA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"SAL\u00c1TOV\u00c1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"VOS\u00c1TKOV\u00c1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"ST\u00c1RKA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"HAMPL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"19169","published-online":{"date-parts":[[2017,9,16]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"AZIZIEH F, ALYAHYA KO, RAGHUPATHY R: Association between levels of vitamin D and inflammatory markers in healthy women. 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