{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:43:34Z","timestamp":1788972214373,"version":"build-2803163510"},"reference-count":77,"publisher":"Institute of Physiology of the Czech Academy of Sciences","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Res"],"published-print":{"date-parts":[[2019,12,30]]},"abstract":"<jats:p>Methamphetamine is one of the most abused hard drugs in the Czech Republic. Its popularity is high not only in Eastern Bloc of Europe but is growing in other countries around the world, including the United States. In addition, methamphetamine abuse increases in drug addicts during pregnancy. Although research into the long-term effects of prenatal methamphetamine exposure has been ongoing for many years, the exact mechanism of action and factors that may influence the effect of this drug are still not fully understood. There have been many studies that investigated the effects of addictive substances on the behavior and cognitive function of individuals during adolescence. Some studies have shown prenatal or perinatal influences, e.g. drugs, stress, hypoxia, and malnutrition, can affect drug sensitivity or drug-seeking behavior in adulthood. However, when these factors are most impactful, i.e. prenatal vs. perinatal, and which stages of the prenatal and perinatal periods are the most sensitive to these factors is not yet clear. Our laboratory specializes in research on the effects of drugs (especially methamphetamine) on rat mothers and their offspring during postnatal development, adolescence, and adulthood. This review summarizes our past results on the long-term effects of methamphetamine on the mother and her offspring, its mechanism of action, the role of maternal care, the possible emergence of long-term sensitization, and the critical neurodevelopmental periods for methamphetamine exposure.<\/jats:p>","DOI":"10.33549\/physiolres.934360","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T04:11:23Z","timestamp":1580271083000},"page":"S219-S231","source":"Crossref","is-referenced-by-count":18,"title":["Review of Long-Term Consequences of Maternal Methamphetamine Exposure"],"prefix":"10.33549","author":[{"given":"R.","family":"\u0160LAMBEROV\u00c1","sequence":"first","affiliation":[{"name":"Department of Physiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"19169","published-online":{"date-parts":[[2019,12,20]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"ACUFF-SMITH KD, GEORGE M, LORENS SA, VORHEES CV: Preliminary evidence for methamphetamine-induced behavioral and ocular effects in rat offspring following exposure during early organogenesis. Psychopharmacology 109: 255-263, 1992.","DOI":"10.1007\/bf02245871"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"ACUFF-SMITH KD, SCHILLING MA, FISHER JE, VORHEES CV: Stage-specific effects of prenatal d-methamphetamine exposure on behavioral and eye development in rats. Neurotoxicol Teratol 18: 199-215, 1996.","DOI":"10.1016\/0892-0362(95)02015-2"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"ANDERSEN SL: Stimulants and the developing brain. Trends Pharmacol Sci 26: 237-243, 2005.","DOI":"10.1016\/j.tips.2005.03.009"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"BARTU A, DUSCI LJ, ILETT KF: Transfer of methylamphetamine and amphetamine into breast milk following recreational use of methylamphetamine. Br J Clin Pharmacol 67: 455-459, 2009.","DOI":"10.1111\/j.1365-2125.2009.03366.x"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"BELIN D, MAR AC, DALLEY JW, ROBBINS TW, EVERITT BJ: High impulsivity predicts the switch to compulsive cocaine-taking. Science 320: 1352-1355, 2008.","DOI":"10.1126\/science.1158136"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"BERKE JD, HYMAN SE: Addiction, dopamine, and the molecular mechanisms of memory. Neuron 25: 515-532, 2000.","DOI":"10.1016\/s0896-6273(00)81056-9"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"BERN\u00c1\u0160KOV\u00c1 K, MAT\u011aJOVSK\u00c1 I, \u0160LAMBEROV\u00c1 R: Postnatal challenge dose of methamphetamine amplifies anticonvulsant effects of prenatal methamphetamine exposure on epileptiform activity induced by electrical stimulation in adult male rats. Exp Neurol 229: 282-287, 2011.","DOI":"10.1016\/j.expneurol.2011.02.011"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"BOCKHORST KH, NARAYANA PA, LIU R, AHOBILA-VIJJULA P, RAMU J, KAMEL M, WOSIK J, BOCKHORST T, HAHN K, HASAN KM, PEREZ-POLO JR: Early postnatal development of rat brain: in vivo diffusion tensor imaging. J Neurosci Res 86: 1520-1528, 2008.","DOI":"10.1002\/jnr.21607"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"BUBEN\u00cdKOV\u00c1-VALE\u0160OV\u00c1 V, KA\u010cER P, SYSLOV\u00c1 K, RAMBOUSEK L, JANOVSK\u00dd M, SCHUTOV\u00c1 B, HRUB\u00c1 L, \u0160LAMBEROV\u00c1 R: Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring. Int J Dev Neurosci 27: 525-530, 2009.","DOI":"10.1016\/j.ijdevneu.2009.06.012"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"CHO DH, LYU HM, LEE HB, KIM PY, CHIN K: Behavioral teratogenicity of methamphetamine. J Toxicol Sci 16 (Suppl 1): 37-49, 1991.","DOI":"10.2131\/jts.16.supplementi_37"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"CLANCY B, FINLAY BL, DARLINGTON RB, ANAND KJ: Extrapolating brain development from experimental species to humans. Neurotoxicology 28: 931-937, 2007.","DOI":"10.1016\/j.neuro.2007.01.014"},{"key":"ref11","unstructured":"DATTEL BJ: Substance abuse in pregnancy. Semin Perinatol 14: 179-187, 1990."},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"DEFALQUE RJ, WRIGHT AJ: Methamphetamine for Hitler's Germany: 1937 to 1945. Bull Anesth Hist 29: 21-24, 32, 2011.","DOI":"10.1016\/S1522-8649(11)50016-2"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"DEJONG W: Relapse prevention: an emerging technology for promoting long-term drug abstinence. Int J Addict 29: 681-705, 1994.","DOI":"10.3109\/10826089409047904"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"DELLA GROTTA S, LAGASSE LL, ARRIA AM, DERAUF C, GRANT P, SMITH LM, SHAH R, HUESTIS M, LIU J, LESTER BM: Patterns of methamphetamine use during pregnancy: results from the Infant Development, Environment, and Lifestyle (IDEAL) Study. Matern Child Health J 14: 519-527, 2010.","DOI":"10.1007\/s10995-009-0491-0"},{"key":"ref15","unstructured":"DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS FOURTH EDITION, American Psychiatric Association, 2000, 943 p."},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"ESTELLES J, RODRIGUEZ-ARIAS M, MALDONADO C, AGUILAR MA, MINARRO J: Gestational exposure to cocaine alters cocaine reward. Behav Pharmacol 17: 509-515, 2006.","DOI":"10.1097\/00008877-200609000-00017"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"EVERITT BJ, BELIN D, ECONOMIDOU D, PELLOUX Y, DALLEY JW, ROBBINS TW: Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction. Philos Trans R Soc Lond B Biol Sci 363: 3125-3135, 2008.","DOI":"10.1098\/rstb.2008.0089"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"EVERITT BJ, ROBBINS TW: Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 8: 1481-1489, 2005.","DOI":"10.1038\/nn1579"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"FOX WM: Reflex-ontogeny and behavioural development of the mouse. Anim Behav 13: 234-241, 1965.","DOI":"10.1016\/0003-3472(65)90041-2"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"FRA\u0147KOV\u00c1 S: Drug-induced changes in the maternal behavior of rats. Psychopharmacology (Berl) 53: 83-87, 1977.","DOI":"10.1007\/bf00426698"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"FUJ\u00c1KOV\u00c1-LIPSKI M, KAPING D, \u0160\u00cdROV\u00c1 J, HOR\u00c1\u010cEK J, P\u00c1LEN\u00cd\u010cEK T, ZACH P, KLASCHKA J, KA\u010cER P, SYSLOV\u00c1 K, VRAJOV\u00c1 M, BUBEN\u00cdKOV\u00c1-VALE\u0160OV\u00c1 V, BESTE C, \u0160LAMBEROV\u00c1 R: Trans-generational neurochemical modulation of methamphetamine in the adult brain of the Wistar rat. Arch Toxicol 91: 3373-3384, 2017.","DOI":"10.1007\/s00204-017-1969-y"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"GERDEMAN GL, PARTRIDGE JG, LUPICA CR, LOVINGER DM: It could be habit forming: drugs of abuse and striatal synaptic plasticity. Trends Neurosci 26: 184-192, 2003.","DOI":"10.1016\/s0166-2236(03)00065-1"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"GROBLER SR, CHIKTE U, WESTRAAT J: The pH levels of different methamphetamine drug samples on the street market in Cape Town. ISRN Dent 2011: 974768, 2011.","DOI":"10.5402\/2011\/974768"},{"key":"ref24","unstructured":"GROBSTEIN C: Environmental Influences on Genetic Expression. Government Printing Office, Washington, 1970."},{"key":"ref25","doi-asserted-by":"publisher","unstructured":"HORGER BA, GILES MK, SCHENK S: Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine. Psychopharmacology (Berl) 107: 271-276, 1992.","DOI":"10.1007\/bf02245147"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"HREB\u00cd\u010cKOV\u00c1 I, MALINOV\u00c1-\u0160EV\u010c\u00cdKOV\u00c1 M, MAC\u00daCHOV\u00c1 E, NOHEJLOV\u00c1 K, \u0160LAMBEROV\u00c1 R: Exposure to methamphetamine during first and second half of prenatal period and its consequences on cognition after long-term application in adulthood. Physiol Res 63 (Suppl 4): S535-S545, 2014.","DOI":"10.33549\/physiolres.932927"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"HREB\u00cd\u010cKOV\u00c1 I, \u0160EV\u010c\u00cdKOV\u00c1 M, MAC\u00daCHOV\u00c1 E, \u0160LAMBEROV\u00c1 R: How methamphetamine exposure during different neurodevelopmental stages affects social behavior of adult rats? Physiol Behav 179: 391-400, 2017.","DOI":"10.1016\/j.physbeh.2017.07.009"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"HREB\u00cd\u010cKOV\u00c1 I, \u0160EV\u010c\u00cdKOV\u00c1 M, NOHEJLOV\u00c1 K, \u0160LAMBEROV\u00c1 R: Does effect from developmental methamphetamine exposure on spatial learning and memory depend on stage of neuroontogeny? Physiol Res 65 (Suppl 5): S577-S589, 2016.","DOI":"10.33549\/physiolres.933534"},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"HRUB\u00c1 L, SCHUTOV\u00c1 B, \u0160LAMBEROV\u00c1 R, POMETLOV\u00c1 M, ROKYTA R: Effect of methamphetamine exposure and cross-fostering on sensorimotor development of male and female rat pups. Dev Psychobiol 51: 73-83, 2009.","DOI":"10.1002\/dev.20346"},{"key":"ref30","doi-asserted-by":"publisher","unstructured":"IARIA G, PETRIDES M, DAGHER A, PIKE B, BOHBOT VD: Cognitive strategies dependent on the hippocampus and caudate nucleus in human navigation: variability and change with practice. J Neurosci 23: 5945-5952, 2003.","DOI":"10.1523\/jneurosci.23-13-05945.2003"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"JABLONSKI SA, WILLIAMS MT, VORHEES CV: Neurobehavioral effects from developmental methamphetamine exposure. Curr Top Behav Neurosci 29: 183-230, 2016.","DOI":"10.1007\/7854_2015_405"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"KING JA: Parameters relevant to determining the effect of early experience upon the adult behavior of animals. Psychol Bull 55: 46-58, 1958.","DOI":"10.1037\/h0041002"},{"key":"ref33","unstructured":"K\u0158E\u010cEK J: Effect of ovarectomy of females and oestrogen administration to males during the neonatal critical period on salt intake in adulthood in rats. Physiol Bohemoslov 27: 1-5, 1978."},{"key":"ref34","doi-asserted-by":"publisher","unstructured":"LERI F, FLORES J, RAJABI H, STEWART J: Effects of cocaine in rats exposed to heroin. Neuropsychopharmacology 28: 2102-2116, 2003.","DOI":"10.1038\/sj.npp.1300284"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"LEVINE S: The ontogeny of the hypothalamic-pituitary-adrenal axis. The influence of maternal factors. Ann N Y Acad Sci 746: 275-288; discussion 289-293, 1994.","DOI":"10.1111\/j.1749-6632.1994.tb39245.x"},{"key":"ref36","doi-asserted-by":"publisher","unstructured":"MAC\u00daCHOV\u00c1 E, \u0160EV\u010c\u00cdKOV\u00c1 M, HREB\u00cd\u010cKOV\u00c1 I, NOHEJLOV\u00c1 K, \u0160LAMBEROV\u00c1 R: How various drugs affect anxiety-related behavior in male and female rats prenatally exposed to methamphetamine. Int J Dev Neurosci 51: 1-11, 2016.","DOI":"10.1016\/j.ijdevneu.2016.04.001"},{"key":"ref37","doi-asserted-by":"publisher","unstructured":"MALANGA CJ, KOSOFSKY BE: Does drug abuse beget drug abuse? Behavioral analysis of addiction liability in animal models of prenatal drug exposure. Brain Res Dev Brain Res 147: 47-57, 2003.","DOI":"10.1016\/j.devbrainres.2003.09.019"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"MALINOV\u00c1-\u0160EV\u010c\u00cdKOV\u00c1 M, HREB\u00cd\u010cKOV\u00c1 I, MAC\u00daCHOV\u00c1 E, NOV\u00c1 E, POMETLOV\u00c1 M, \u0160LAMBEROV\u00c1 R: Differences in maternal behavior and development of their pups depend on the time of methamphetamine exposure during gestation period. Physiol Res 63 (Suppl 4): S559-S572, 2014.","DOI":"10.33549\/physiolres.932925"},{"key":"ref39","doi-asserted-by":"publisher","unstructured":"MARTIN JC, MARTIN DC, RADOW B, SIGMAN G: Growth, development and activity in rat offspring following maternal drug exposure. Exp Aging Res 2: 235-251, 1976.","DOI":"10.1080\/03610737608257179"},{"key":"ref40","doi-asserted-by":"publisher","unstructured":"MARWICK C: NIDA seeking data on effect of fetal exposure to methamphetamine. JAMA 283: 2225-2226, 2000.","DOI":"10.1001\/jama.283.17.2225-jmn0503-2-1"},{"key":"ref41","doi-asserted-by":"publisher","unstructured":"ORO AS, DIXON SD: Perinatal cocaine and methamphetamine exposure: maternal and neonatal correlates. J Pediatr 111: 571-578, 1987.","DOI":"10.1016\/s0022-3476(87)80125-7"},{"key":"ref42","doi-asserted-by":"crossref","unstructured":"PARENT A: Extrinsic connections of the basal ganglia. TINS 13: 254-258, 1990.","DOI":"10.1016\/0166-2236(90)90105-J"},{"key":"ref43","doi-asserted-by":"publisher","unstructured":"PICCIRILLO M, ALPERT JE, COHEN DJ, SHAYWITZ BA: Amphetamine and maternal behavior: dose response relationships. Psychopharmacology (Berl) 70: 195-199, 1980.","DOI":"10.1007\/bf00435314"},{"key":"ref44","doi-asserted-by":"crossref","unstructured":"PLESSINGER MA: Prenatal exposure to amphetamines. Risks and adverse outcomes in pregnancy. Obstet Gynecol Clin North Am 25: 119-138, 1998.","DOI":"10.1016\/S0889-8545(05)70361-2"},{"key":"ref45","doi-asserted-by":"publisher","unstructured":"RAMBOUSEK L, KA\u010cER P, SYSLOV\u00c1 K, BUMBA J, BUBEN\u00cdKOV\u00c1-VALE\u0160OV\u00c1 V, \u0160LAMBEROV\u00c1 R: Sex differences in methamphetamine pharmacokinetics in adult rats and its transfer to pups through the placental membrane and breast milk. Drug Alcohol Depend 139: 138-144, 2014.","DOI":"10.1016\/j.drugalcdep.2014.03.023"},{"key":"ref46","unstructured":"REYNOLDS AK, RANDALL LO: Morphine and allied drugs. University of Toronto Press, Toronto, 1957."},{"key":"ref47","doi-asserted-by":"publisher","unstructured":"RICE D, BARONE S JR: Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 108 (Suppl 3): 511-533, 2000.","DOI":"10.1289\/ehp.00108s3511"},{"key":"ref48","doi-asserted-by":"publisher","unstructured":"ROBINSON TE, BECKER JB: Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis. Brain Res 396: 157-198, 1986.","DOI":"10.1016\/0165-0173(86)90002-0"},{"key":"ref49","doi-asserted-by":"publisher","unstructured":"ROCHA BA, MEAD AN, KOSOFSKY BE: Increased vulnerability to self-administer cocaine in mice prenatally exposed to cocaine. Psychopharmacology (Berl) 163: 221-229, 2002.","DOI":"10.1007\/s00213-002-1140-0"},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"SCOTT JP: Critical periods in behavioral development. Science 138: 949-958, 1962.","DOI":"10.1126\/science.138.3544.949"},{"key":"ref51","doi-asserted-by":"publisher","unstructured":"SEMPLE BD, BLOMGREN K, GIMLIN K, FERRIERO DM, NOBLE-HAEUSSLEIN LJ: Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species. Prog Neurobiol 106-107: 1-16, 2013.","DOI":"10.1016\/j.pneurobio.2013.04.001"},{"key":"ref52","doi-asserted-by":"publisher","unstructured":"SHUSTER L, YU G, BATES A: Sensitization to cocaine stimulation in mice. Psychopharmacology (Berl) 52: 185-190, 1977.","DOI":"10.1007\/bf00439108"},{"key":"ref53","doi-asserted-by":"publisher","unstructured":"STEINER E, VILLEN T, HALLBERG M, RANE A: Amphetamine secretion in breast milk. Eur J Clin Pharmacol 27: 123-124, 1984.","DOI":"10.1007\/bf02395219"},{"key":"ref54","doi-asserted-by":"publisher","unstructured":"STOCKARD CR: Developmental rate and structural expression: an experimental study of twins. 'double monsters' and single deformities, and the interaction among embryonic organs during their origin and development. Am J Anat 28: 115-266, 1921.","DOI":"10.1002\/aja.1000280202"},{"key":"ref55","doi-asserted-by":"publisher","unstructured":"SUZUKI T, FUKUOKA Y, MORI T, MIYATAKE M, NARITA M: Behavioral sensitization to the discriminative stimulus effects of methamphetamine in rats. Eur J. Pharmacol 498: 157-161, 2004.","DOI":"10.1016\/j.ejphar.2004.07.064"},{"key":"ref56","doi-asserted-by":"publisher","unstructured":"\u0160EV\u010c\u00cdKOV\u00c1 M, HREB\u00cd\u010cKOV\u00c1 I, MAC\u00daCHOV\u00c1 E, \u0160LAMBEROV\u00c1 R: The influence of methamphetamine on maternal behavior and development of the pups during the neonatal period. Int J Dev Neurosci 59: 37-46, 2017.","DOI":"10.1016\/j.ijdevneu.2017.03.005"},{"key":"ref57","doi-asserted-by":"crossref","unstructured":"\u0160LAMBEROV\u00c1 R: Drugs in pregnancy: the effects on mother and her progeny. Physiol Res 61 (Suppl 1): S123-S135, 2012.","DOI":"10.33549\/physiolres.932357"},{"key":"ref58","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, CHAROUSOV\u00c1 P, POMETLOV\u00c1 M: Maternal behavior is impaired by methamphetamine administered during pre-mating, gestation and lactation. Reprod Toxicol 20: 103-110, 2005.","DOI":"10.1016\/j.reprotox.2004.11.010"},{"key":"ref59","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, CHAROUSOV\u00c1 P, POMETLOV\u00c1 M: Methamphetamine administration during gestation impairs maternal behavior. Dev Psychobiol 46: 57-65, 2005.","DOI":"10.1002\/dev.20042"},{"key":"ref60","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, MAC\u00daCHOV\u00c1 E, NOHEJLOV\u00c1-DEYKUN K, SCHUTOV\u00c1 B, HRUB\u00c1 L, ROKYTA R: Gender differences in the effect of prenatal methamphetamine exposure and challenge dose of other drugs on behavior of adult rats. Physiol Res 62 (Suppl 1): S99-S108, 2013.","DOI":"10.1097\/01.fbp.0000434822.80441.f3"},{"key":"ref61","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, POMETLOV\u00c1 M, CHAROUSOV\u00c1 P: Postnatal development of rat pups is altered by prenatal methamphetamine exposure. Prog Neuropsychopharmacol Biol Psychiatry 30: 82-88, 2006.","DOI":"10.1016\/j.pnpbp.2005.06.006"},{"key":"ref62","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, POMETLOV\u00c1 M, MAC\u00daCHOV\u00c1 E, NOHEJLOV\u00c1 K, STUCHL\u00cdK A, VALE\u0160 K: Do the effects of prenatal exposure and acute treatment of methamphetamine on anxiety vary depending on the animal model used? Behav Brain Res 292: 361-369, 2015.","DOI":"10.1016\/j.bbr.2015.07.001"},{"key":"ref63","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, POMETLOV\u00c1 M, ROKYTA R: Effect of methamphetamine exposure during prenatal and preweaning periods lasts for generations in rats. Dev Psychobiol 49: 312-322, 2007.","DOI":"10.1002\/dev.20203"},{"key":"ref64","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, POMETLOV\u00c1 M, SCHUTOV\u00c1 B, HRUB\u00c1 L, MAC\u00daCHOV\u00c1 E, NOV\u00c1 E, ROKYTA R: Do prenatally methamphetamine-exposed adult male rats display general predisposition to drug abuse in the Conditioned place preference test? Physiol Res 61 (Suppl 2): S129-S138, 2012.","DOI":"10.1016\/j.bbr.2009.11.001"},{"key":"ref65","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, POMETLOV\u00c1 M, SYLLABOV\u00c1 L, MAN\u010cU\u0160KOV\u00c1 M: Learning in the place navigation task, not the new-learning task, is altered by prenatal methamphetamine exposure. Brain Res Dev Brain Res 157: 217-219, 2005.","DOI":"10.1016\/j.devbrainres.2005.04.005"},{"key":"ref66","doi-asserted-by":"publisher","unstructured":"\u0160LAMBEROV\u00c1 R, SCHUTOV\u00c1 B, HRUB\u00c1 L, POMETLOV\u00c1 M: Does prenatal methamphetamine exposure affect the drug-seeking behavior of adult male rats? Behav Brain Res 224: 50-86, 2011.","DOI":"10.1016\/j.bbr.2011.05.021"},{"key":"ref67","doi-asserted-by":"publisher","unstructured":"TRONICK EZ, BEEGHLY M: Prenatal cocaine exposure, child development, and the compromising effects of cumulative risk. Clin Perinatol 26: 151-171, 1999.","DOI":"10.1016\/s0095-5108(18)30076-9"},{"key":"ref68","doi-asserted-by":"publisher","unstructured":"VALVASSORI SS, FREY BN, MARTINS MR, REUS GZ, SCHIMIDTZ F, INACIO CG, KAPCZINSKI F, QUEVEDO J: Sensitization and cross-sensitization after chronic treatment with methylphenidate in adolescent Wistar rats. Behav Pharmacol 18: 205-212, 2007.","DOI":"10.1097\/fbp.0b013e328153daf5"},{"key":"ref69","unstructured":"VAV\u0158\u00cdNKOV\u00c1 B, BINDER T, \u017dIVN\u00dd J: Characteristics of a population of drug dependent pregnant women in the Czech Republic. (Article in Czech) Ceska Gynekol 66: 285-291, 2001."},{"key":"ref70","doi-asserted-by":"publisher","unstructured":"VELA G, MARTIN S, GARCIA-GIL L, CRESPO JA, RUIZ-GAYO M, JAVIER FERNANDEZ-RUIZ J, GARCIA-LECUMBERRI C, PELAPRAT D, FUENTES JA, RAMOS JA, AMBROSIO E: Maternal exposure to delta9-tetrahydrocannabinol facilitates morphine self-administration behavior and changes regional binding to central mu opioid receptors in adult offspring female rats. Brain Res 807: 101-109, 1998.","DOI":"10.1016\/s0006-8993(98)00766-5"},{"key":"ref71","doi-asserted-by":"publisher","unstructured":"VITERI OA, SOTO EE, BAHADO-SINGH RO, CHRISTENSEN CW, CHAUHAN SP, SIBAI BM: Fetal anomalies and long-term effects associated with substance abuse in pregnancy: a literature review. Am J Perinatol 32: 405-416, 2015.","DOI":"10.1055\/s-0034-1393932"},{"key":"ref72","doi-asserted-by":"publisher","unstructured":"VOLKOW ND, WISE RA: How can drug addiction help us understand obesity? Nat Neurosci 8: 555-560, 2005.","DOI":"10.1038\/nn1452"},{"key":"ref73","doi-asserted-by":"publisher","unstructured":"VORHEES CV, ACUFF-SMITH KD: Prenatal methamphetamine-induced anophthalmia in rats. Neurotoxicol Teratol 12: 409, 1990.","DOI":"10.1016\/0892-0362(90)90062-h"},{"key":"ref74","doi-asserted-by":"publisher","unstructured":"WILLIAMS MT, MORAN MS, VORHEES CV: Refining the critical period for methamphetamine-induced spatial deficits in the Morris water maze. Psychopharmacology (Berl) 168: 329-338, 2003.","DOI":"10.1007\/s00213-003-1433-y"},{"key":"ref75","unstructured":"YAMAMOTO Y, YAMAMOTO K, FUKUI Y, KURISHITA A: Teratogenic effects of methamphetamine in mice. Nippon Hoigaku Zasshi 46: 126-131, 1992."},{"key":"ref76","doi-asserted-by":"crossref","unstructured":"YAMAMOTOV\u00c1 A, \u0160LAMBEROV\u00c1 R: Behavioral and antinociceptive effects of different psychostimulant drugs in prenatally methamphetamine-exposed rats. Physiol Res 61 (Suppl 2): S139-S147, 2012.","DOI":"10.33549\/physiolres.932428"}],"container-title":["Physiological Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T13:06:40Z","timestamp":1614172000000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.biomed.cas.cz\/physiolres\/pdf\/2019\/68_S219.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,20]]},"references-count":77,"URL":"https:\/\/doi.org\/10.33549\/physiolres.934360","relation":{},"ISSN":["1802-9973","0862-8408"],"issn-type":[{"value":"1802-9973","type":"electronic"},{"value":"0862-8408","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12,20]]}}}