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The dependence of Tg on iodine can be described by a U-shaped curve. Thyroglobulin in serum is elevated in thyroid disease mainly in hyperthyroidism (diagnosis E05 of WHO ICD-10 codes) and in goiter (diagnosis E04 of WHO ICD-10 codes). Tg values decrease below 20 \u00b5g\/l after effective treatment of patients with thyroid disease. Thyroglobulin may thus be an indicator of thyroid stabilization and the success of the thyroid gland treatment.<\/jats:p>","DOI":"10.33549\/physiolres.934514","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T12:21:07Z","timestamp":1602850867000},"page":"S225-S236","source":"Crossref","is-referenced-by-count":40,"title":["Iodine, Thyroglobulin and Thyroid Gland"],"prefix":"10.33549","author":[{"given":"R.","family":"B\u00cdLEK","sequence":"first","affiliation":[{"name":"Institute of Endocrinology, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"DVO\u0158\u00c1KOV\u00c1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"GRIMMICHOV\u00c1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"JISKRA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"19169","published-online":{"date-parts":[[2020,10,16]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"ANDERSEN SL, LAURBERG P: Iodine supplementation in pregnancy and the dilemma of ambiguous recommendations. 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