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Patients: increased levels of CRP (p&lt;0.001), chemerin (p&lt;0.05), osteopontin (p&lt;0.05) and decreased levels of fetuin-A (p&lt;0.05), significant relationships between CRP and fetuin-A (rho=0.530, p&lt;0.01), CRP and chemerin (rho=0.543, p&lt;0.01), CRP and age (rho=0.590, p&lt;0.001), osteopontin and fetuin-A (r=-0.415, p&lt;0.05), chemerin and PASI score \n(rho=-0.424, p&lt;0.05). We confirmed specific roles of the biomarkers in psoriasis. CRP, fetuin-A and osteopontin could be considered appropriate markers for the detection of early stages of cardiovascular diseases.<\/jats:p>","DOI":"10.33549\/physiolres.934654","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T13:20:35Z","timestamp":1627478435000},"page":"383-391","source":"Crossref","is-referenced-by-count":13,"title":["C-Reactive Protein, Chemerin, Fetuin-A and Osteopontin as Predictors of Cardiovascular Risks in Persons With Psoriasis Vulgaris"],"prefix":"10.33549","author":[{"given":"P","family":"BORSKY","sequence":"first","affiliation":[{"name":"Institute of Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z","family":"FIALA","sequence":"additional","affiliation":[{"name":"Institute of Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"ANDRYS","sequence":"additional","affiliation":[{"name":"Institute of Clinical Immunology and Allergology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"BERANEK","sequence":"additional","affiliation":[{"name":"Institute of Clinical Biochemistry and Diagnostics, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"HAMAKOVA","sequence":"additional","affiliation":[{"name":"Clinic of Dermal and Venereal Diseases, University Hospital, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"KREMLACEK","sequence":"additional","affiliation":[{"name":"Institute of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"MALKOVA","sequence":"additional","affiliation":[{"name":"Institute of Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"SVADLAKOVA","sequence":"additional","affiliation":[{"name":"Institute of Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"KREJSEK","sequence":"additional","affiliation":[{"name":"Institute of Clinical Immunology and Allergology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"PALICKA","sequence":"additional","affiliation":[{"name":"Institute of Clinical Biochemistry and Diagnostics, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"REHACEK","sequence":"additional","affiliation":[{"name":"Transfusion Center, University Hospital, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"KOTINGOVA","sequence":"additional","affiliation":[{"name":"Institute of Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"BORSKA","sequence":"additional","affiliation":[{"name":"Institute of Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"19169","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"ABDEL-MAWLA MY, EL-KASHESHY KA, GHONEMY S, AL BALAT W, ELSAYED AA: Role of osteopontin in psoriasis: An immunohistochemical study. 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