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A large number of countries, have since been forced to take precautions such as curfews, lockdowns, wearing facemasks etc. Even with vaccines being produced in mass numbers, lack of targeted therapy continues to be a major problem. According to studies so far it seems that elderly people are more vulnerable to severe symptoms while children tend to by asymptomatic or have milder form the disease. In our review, we focused on gathering data about the virus itself, its characteristics, paths of transmission, and its effect on hormone production and secretion. In such, there is insufficient information in the literature worldwide, especially the ones that focus on the effect of COVID-19 on individual organs systems within the human body. Hence, the present evidence-based study focused on the possible effects of COVID-19 on adrenal gland and gonads i.e. on the process of steroidogenesis and fertility.<\/jats:p>","DOI":"10.33549\/physiolres.934756","type":"journal-article","created":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T11:44:36Z","timestamp":1639741476000},"page":"S161-S175","source":"Crossref","is-referenced-by-count":2,"title":["Is There Impact of the SARS-CoV-2 Pandemic on Steroidogenesis and Fertility?"],"prefix":"10.33549","author":[{"given":"N","family":"KN\u00cd\u017dATOV\u00c1","sequence":"first","affiliation":[{"name":"Institute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"MASS\u00c1NYI","sequence":"additional","affiliation":[{"name":"AgroBiotech Research Centre, Faculty of Biotechnology and Food Resources, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"ROYCHOUDHURY","sequence":"additional","affiliation":[{"name":"Department of Life Science and Bioinformatics, Assam University, Silchar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"GUHA","sequence":"additional","affiliation":[{"name":"Department of Zoology, Garhbeta College, Paschim Medinipur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"GREIFOV\u00c1","sequence":"additional","affiliation":[{"name":"Institute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"TOK\u00c1ROV\u00c1","sequence":"additional","affiliation":[{"name":"Institute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"JAMBOR","sequence":"additional","affiliation":[{"name":"BioFood Centre, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"MASS\u00c1NYI","sequence":"additional","affiliation":[{"name":"Institute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"LUK\u00c1\u010c","sequence":"additional","affiliation":[{"name":"Institute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Nitra, Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"19169","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"AKBAS EM, AKBAS N: COVID-19, adrenal gland, glucocorticoids, and adrenal insufficiency. 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