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Dysregulation of epitranscriptomic machinery affecting these modifications vastly changes the cardiac phenotype and is linked with many cardiovascular diseases such as myocardial infarction, cardiomyopathies, or heart failure. Thus, a deeper understanding of these epitranscriptomic changes and their regulatory mechanisms can enhance our knowledge of the molecular underpinnings of prevalent cardiac diseases, potentially paving the way for novel therapeutic strategies.<\/jats:p>","DOI":"10.33549\/physiolres.935265","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T08:08:24Z","timestamp":1712045304000},"source":"Crossref","is-referenced-by-count":9,"title":["Epitranscriptomic regulations in the heart"],"prefix":"10.33549","author":[{"given":"D","family":"Benak","sequence":"first","affiliation":[{"name":"Laboratory of Developmental Cardiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic. daniel.benak@fgu.cas.cz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Kolar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Hlavackova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"19169","published-online":{"date-parts":[[2024,3,22]]},"reference":[{"key":"ref0","unstructured":"1.\tCrick FH. 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