{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:25:24Z","timestamp":1721348724754},"reference-count":15,"publisher":"Institute of Physiology of the Czech Academy of Sciences","issue":"3\/2024","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Res"],"abstract":"<jats:p>This study aimed to investigate changes in the H-reflex recruitment curve in compressive radiculopathy, specifically assessing differences between symptomatic and asymptomatic limbs in patients with unilateral S1 radiculopathy through derived parameters. A total of 24 volunteers (15 male and 9 female, aged between 22 and 60 years) with confirmed nerve root compression in the L5\/S1 segment participated. Nerve root compression was verified through clinical MRI examination and attributed to disc protrusion, spinal canal stenosis, or isthmic spondylolisthesis of L5\/S1. Analysis revealed no difference in M-wave threshold intensity between symptomatic and non-symptomatic limbs. However, the H-reflex exhibited a trend toward increased threshold intensity in the symptomatic limb. Notably, a significant decrease in the slope of the H-reflex was observed on the symptomatic side, and the maximal H-reflex amplitude proved to be markedly different between the two limbs. The Hmax\/Mmax ratio demonstrated a significant decrease in the symptomatic limb, indicating reduced effectiveness of signal translation. In conclusion, our findings emphasize the importance of H-reflex parameters in evaluating altered recruitment curves, offering valuable insights for neurological examinations. The observed differences in maximal values of M-wave, H-reflex, and their ratio in affected and unaffected limbs can enhance the diagnostic process for lumbosacral unilateral radiculopathy and contribute to a standardized approach in clinical assessments.<\/jats:p>","DOI":"10.33549\/physiolres.935325","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T13:30:00Z","timestamp":1721309400000},"page":"427-433","source":"Crossref","is-referenced-by-count":0,"title":["Neurophysiological Assessment of H-Reflex Alterations in Compressive Radiculopathy"],"prefix":"10.33549","author":[{"given":"P","family":"\u0160\u00e1dek","sequence":"first","affiliation":[{"name":"Biomedical Department, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Hru\u0161kov\u00e1","sequence":"additional","affiliation":[{"name":"Biomedical Department, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Ostr\u00fd","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Neurooncology, The First Faculty of Medicine Charles University and Military University Hospital, Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Ot\u00e1hal","sequence":"additional","affiliation":[{"name":"Laboratory of Developmental Epileptology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"19169","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.\tFerreira ML, Luca DL, Haile LM, Steinmetz JD, Culbreth GT, Cross M, Kopec JA, Ferreira PH, ET AL. 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