{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T04:15:19Z","timestamp":1728360919900},"reference-count":8,"publisher":"Aerospace Medical Association","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["aerosp med hum perform"],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"BACKGROUND:<\/jats:bold> Charcot-Marie-Tooth disease (CMT) is a rare hereditary motor and sensory neuropathy. This is a report of a pilot with this condition with a discussion of the challenges for the regulator in the assessment for medical certification of pilots with a neurological disability.CASE\n REPORT:<\/jats:bold> A pilot with CMTX1 declared his condition to the United Kingdom Civil Aviation Authority when his brother was diagnosed with the same condition. Apart from high arched feet and some difficulty playing sports, he had no problems until his mid-forties, when he very slowly developed\n increasing weakness with foot dorsiflexion and later wasting and weakness of the small hand muscles. He reported no problems with any flying activity. On clinical examination, it seemed likely that the disability would have an impact on his ability to undertake all the flying tasks of a commercial\n pilot, including those required in emergencies.DISCUSSION:<\/jats:bold> A modified Medical Flight Test (MFT) specifically tailored by the regulator to test areas of functional impairment allowed the successful certificatory assessment of a pilot with this condition; an approach which could apply\n to any pilot with a rare neurological disability.Jagathesan T, OBrien M, Rattray A. Certification of a pilot with Charcot-Marie-Tooth disease<\/jats:italic>. Aerosp Med Hum Perform. 2021; 92(2):124126.<\/jats:bold><\/jats:p>","DOI":"10.3357\/amhp.5711.2021","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T05:18:19Z","timestamp":1611119899000},"page":"124-126","source":"Crossref","is-referenced-by-count":0,"title":["Certification of a Pilot with Charcot-Marie-Tooth Disease"],"prefix":"10.3357","volume":"92","author":[{"given":"Tania","family":"Jagathesan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"OBrien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Rattray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1911","reference":[{"issue":"3","key":"bib1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1159\/000443706","article-title":"Epidemiologic study of Charcot-Marie-Tooth disease: a systematic review","volume":"46","author":"Barreto","year":"2016","journal-title":"Neuroepidemiology."},{"issue":"5","key":"bib2","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1093\/brain\/113.5.1511","article-title":"X-linked dominant hereditary motor and sensory neuropathy","volume":"113","author":"Hahn","year":"1990","journal-title":"Brain."},{"issue":"4","key":"bib3","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/mus.23622","article-title":"Clinical correlates of Charcot-Marie-Tooth disease in patients with pes cavus deformities","volume":"47","author":"Karakis","year":"2013","journal-title":"Muscle Nerve."},{"issue":"7","key":"bib4","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1136\/jnnp-2012-302451","article-title":"Charcot-Marie-Tooth disease: frequency of genetic subtypes and guidelines for genetic testing","volume":"83","author":"Murphy","year":"2012","journal-title":"J Neurol Neurosurg Psychiatry."},{"issue":"2","key":"bib5","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/mus.20776","article-title":"Autosomal-recessive and X-linked forms of hereditary motor and sensory neuropathy in childhood","volume":"36","author":"Ouvrier","year":"2007","journal-title":"Muscle Nerve."},{"issue":"5","key":"bib6","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/WCO.0000000000000474","article-title":"New developments in Charcot-Marie-Tooth neuropathy and related diseases","volume":"30","author":"Pareyson","year":"2017","journal-title":"Curr Opin Neurol."},{"issue":"1","key":"bib7","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/ana.22166","article-title":"Charcot-Marie-Tooth disease subtypes and genetic testing strategies","volume":"69","author":"Saporta","year":"2011","journal-title":"Ann Neurol."},{"issue":"11","key":"bib8","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1212\/01.wnl.0000256709.08271.4d","article-title":"CMT1X phenotypes represent loss of GJB1 gene function","volume":"68","author":"Shy","year":"2007","journal-title":"Neurology."}],"container-title":["Aerospace Medicine and Human Performance"],"original-title":[],"link":[{"URL":"https:\/\/asma.kglmeridian.com\/view\/journals\/amhp\/92\/2\/article-p124.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/asma.kglmeridian.com\/downloadpdf\/journals\/amhp\/92\/2\/article-p124.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/asma.kglmeridian.com\/downloadpdf\/journals\/amhp\/92\/2\/article-p124.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T12:22:05Z","timestamp":1728303725000},"score":1,"resource":{"primary":{"URL":"https:\/\/asma.kglmeridian.com\/view\/journals\/amhp\/92\/2\/article-p124.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,1]]},"references-count":8,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3357\/amhp.5711.2021","relation":{},"ISSN":["2375-6314","2375-6322"],"issn-type":[{"type":"print","value":"2375-6314"},{"type":"electronic","value":"2375-6322"}],"subject":[],"published":{"date-parts":[[2021,2,1]]}}}