{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:48:23Z","timestamp":1740098903125,"version":"3.37.3"},"reference-count":18,"publisher":"Aerospace Medical Association","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["aerosp med hum perform"],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Cryptogenic stroke leading to cerebellar infarction is a rare but serious cause of acute nausea and vomiting. This has the potential of devastating consequences if this occurs in aviators during flight. We present a case of cryptogenic stroke causing incapacitating\n nausea and vomiting in a U.S. Air Force pilot.<jats:bold>CASE REPORT:<\/jats:bold> A 36-yr-old active-duty U.S. Air Force male pilot developed acute onset severe vertigo, nausea, and vomiting during initial descent. Initial computed tomography imaging was normal and his initial assessment yielded a diagnosis\n of benign paroxysmal positional vertigo. MRI-Brain at 1 mo revealed a small right inferomedial cerebellar infarct. Echocardiography revealed a patent foramen ovale and bilateral atrial enlargement. He made a full neurological recovery and was eventually returned to active flight status with\n Flying Class IIC waiver.<jats:bold>DISCUSSION:<\/jats:bold> Cryptogenic stroke caused by patent foramen ovale (PFO) is uncommon. However, this is increased in patients younger than 50 yr of age. This can lead to an acute incapacitation with varying degrees of dysfunction. There is controversial discussion\n of treatment options for secondary stroke prevention with PFO. However, there is no significant literature on primary prevention in these patients. A small subset of patients benefit from closure of PFO and most patients benefit from antiplatelet therapy after a stroke occurs. There may also\n be a significant subset of patients with PFO that may benefit from antiplatelet therapy as a primary prevention of stroke.<jats:bold>Lytle ME, Martin BR. <jats:italic>Acute cerebellar stroke in a military active-duty pilot<\/jats:italic>. Aerosp Med Hum Perform. 2021; 92(11): 919\u2013923<\/jats:bold>.<\/jats:p>","DOI":"10.3357\/amhp.5821.2021","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T08:22:00Z","timestamp":1637828520000},"page":"919-923","source":"Crossref","is-referenced-by-count":0,"title":["Acute Cerebellar Stroke in a Military Active-Duty Pilot"],"prefix":"10.3357","volume":"92","author":[{"given":"Mark E.","family":"Lytle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryant R.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1911","reference":[{"issue":"6923","key":"B1","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1136\/bmj.308.6923.235","article-title":"Collaborative overview of randomized trials of antiplatelet therapy-III: reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients","volume":"308","year":"1994","journal-title":"BMJ."},{"issue":"1","key":"B2","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1146\/annurev-physiol-012110-142305","article-title":"Venous valvular stasis-associated hypoxia and thrombosis: what is the link?","volume":"73","author":"Bovill","year":"2011","journal-title":"Annu Rev Physiol."},{"issue":"12","key":"B3","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1056\/NEJMoa1301440","article-title":"Closure of patent foramen ovale versus medical therapy after cryptogenic stroke","volume":"368","author":"Carroll","year":"2013","journal-title":"N Engl J Med."},{"issue":"2, Suppl","key":"B4","first-page":"E278S","article-title":"Prevention of VTE in orthopedic surgery patients","volume-title":"Antithrombotic therapy and prevention of thrombosis","volume":"141","author":"Falck-Ytter","year":"2012"},{"issue":"11","key":"B5","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S1474-4422(10)70251-9","article-title":"Aetiological diagnosis of ischaemic stroke in young adults","volume":"9","author":"Ferro","year":"2010","journal-title":"Lancet Neurol."},{"issue":"11","key":"B6","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1056\/NEJMoa1009639","article-title":"Closure or medical therapy for cryptogenic stroke with patent foramen ovale","volume":"366","author":"Furlan","year":"2012","journal-title":"N Engl J Med."},{"issue":"3","key":"B7","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/bjs.1800680308","article-title":"The PO2 in venous valve pockets: its possible bearing on thrombogenesis","volume":"68","author":"Hamer","year":"1981","journal-title":"Br J Surg."},{"issue":"4","key":"B8","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S1474-4422(13)70310-7","article-title":"Embolic strokes of undetermined source; the case for a new clinical construct","volume":"13","author":"Hart","year":"2014","journal-title":"Lancet Neurol."},{"issue":"11","key":"B9","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1056\/NEJMoa1705915","article-title":"Patent foramen ovale closure or anticoagulation vs antiplatelets after stroke","volume":"377","author":"Mas","year":"2017","journal-title":"N Engl J Med."},{"issue":"12","key":"B10","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1056\/NEJMoa1211716","article-title":"Percutaneous closure of patent foramen ovale in cryptogenic embolism","volume":"368","author":"Meier","year":"2013","journal-title":"N Engl J Med."},{"issue":"8","key":"B11","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1212\/WNL.0000000000002961","article-title":"Practice advisory: recurrent stroke with patent foramen ovale (update of practice parameter) [RETIRED]: report of the guideline development, dissemination, and implementation: Subcommittee of the American Academy of Neurology","volume":"87","author":"Mess","year":"2016","journal-title":"Neurology."},{"issue":"11","key":"B12","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1056\/NEJMoa1610057","article-title":"Long-term outcomes of patent foramen ovale closure or medical therapy after stroke","volume":"377","author":"Saver","year":"2017","journal-title":"N Engl J Med."},{"key":"B13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.2147\/VHRM.S53203","article-title":"Strokes in young adults: epidemiology and prevention","volume":"11","author":"Smajlovi","year":"2015","journal-title":"Vasc Health Risk Manag."},{"issue":"11","key":"B14","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1056\/NEJMoa1707404","article-title":"Patent foramen ovale closure or antiplatelet therapy for cryptogenic stroke","volume":"377","author":"Sndergaard","year":"2017","journal-title":"N Engl J Med."},{"issue":"8","key":"B15","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1253\/circj.CJ-16-0534","article-title":"Patent foramen ovale and stroke","volume":"80","author":"Sun","year":"2016","journal-title":"Circ J."},{"issue":"1","key":"B16","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1513\/pats.200407-038MS","article-title":"The role of smoking in coagulation and thromboembolism in chronic obstructive pulmonary disease","volume":"2","author":"Tapson","year":"2005","journal-title":"Proc Am Thorac Soc."},{"issue":"03","key":"B17","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1160\/TH04-04-0251","article-title":"The ABO blood group genotype and factor VIII levels as independent risk factors for venous thromboembolism","volume":"93","author":"Tirado","year":"2005","journal-title":"Thromb Haemost."},{"issue":"5","key":"B18","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/NRL.0000000000000200","article-title":"Is patent foramen ovale closure more effective than medical therapy in preventing stroke recurrence in patients with cryptogenic stroke? A critically appraised topic","volume":"23","author":"Valencia-Sanchez","year":"2018","journal-title":"Neurologist."}],"container-title":["Aerospace Medicine and Human Performance"],"original-title":[],"link":[{"URL":"https:\/\/asma.kglmeridian.com\/view\/journals\/amhp\/92\/11\/article-p919.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/asma.kglmeridian.com\/downloadpdf\/journals\/amhp\/92\/11\/article-p919.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/asma.kglmeridian.com\/downloadpdf\/journals\/amhp\/92\/11\/article-p919.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:01:39Z","timestamp":1740096099000},"score":1,"resource":{"primary":{"URL":"https:\/\/asma.kglmeridian.com\/view\/journals\/amhp\/92\/11\/article-p919.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,1]]},"references-count":18,"journal-issue":{"issue":"11"},"URL":"https:\/\/doi.org\/10.3357\/amhp.5821.2021","relation":{},"ISSN":["2375-6314","2375-6322"],"issn-type":[{"type":"print","value":"2375-6314"},{"type":"electronic","value":"2375-6322"}],"subject":[],"published":{"date-parts":[[2021,11,1]]}}}