{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T04:08:35Z","timestamp":1772683715452,"version":"3.50.1"},"reference-count":13,"publisher":"Aerospace Medical Association","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>\n<jats:bold>INTRODUCTION:<\/jats:bold> Motion sickness affecting military pilots and aircrew can impact flight safety and, if severe, can lead to disqualification from flight status. However, due to the common adverse effects of motion sickness pharmaceuticals (e.g., drowsiness), medication options are severely limited. The purpose of this study was to explore the potential utility of a nonpharmaceutical method for motion sickness prevention, specifically an osteopathic manipulative technique (OMT).<\/jats:p>\n<jats:p>\n<jats:bold>METHODS:<\/jats:bold>A novel OMT protocol for the reduction of motion sickness symptoms and severity was evaluated using a sham-controlled, counterbalanced, between-subjects study design. The independent variable was OMT treatment administered prior to the motion sickness-inducing procedure (rotating chair). The primary dependent measures were total and subscale scores from the Motion Sickness Assessment Questionnaire.<\/jats:p>\n<jats:p>\n<jats:bold>RESULTS:<\/jats:bold>The OMT treatment group experienced significantly fewer gastrointestinal (mean scores postprocedure, treatment M = 20.42, sham M = 41.67) and sopite-related (mean scores postprocedure, treatment M = 12.81, sham M = 20.68) symptoms than the sham group while controlling for motion sickness susceptibility. There were no differences between groups with respect to peripheral and central symptoms.<\/jats:p>\n<jats:p>\n<jats:bold>DISCUSSION:<\/jats:bold>The results suggest that the treatment may prevent gastrointestinal (nausea) and sopite-related symptoms (sleepiness). These preliminary findings support further exploration of OMT for the prevention of motion sickness. A more precise evaluation of the mechanism of action is needed. Additionally, the duration of the effects needs to be investigated to determine the usefulness of this technique in training and operational settings.<\/jats:p>\n<jats:p>\n<jats:bold>Thomas VA, Kelley AM, Lee A, Fotopoulos T, Boggs J, Campbell J. <jats:italic>Preliminary evaluation of an osteopathic manipulative treatment to prevent motion sickness<\/jats:italic>. Aerosp Med Hum Perform. 2023; 94(12):934\u2013938.<\/jats:bold>\n<\/jats:p>","DOI":"10.3357\/amhp.6248.2023","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T20:57:48Z","timestamp":1726174668000},"page":"934-938","source":"Crossref","is-referenced-by-count":3,"title":["Preliminary Evaluation of an Osteopathic Manipulative Treatment to Prevent Motion Sickness"],"prefix":"10.3357","volume":"94","author":[{"given":"Virginia A.","family":"Thomas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda M.","family":"Kelley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Fotopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Boggs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1911","reference":[{"key":"B1","series-title":"J Pain Res","first-page":"601","article-title":"Osteopathy for primary headache patients: a systematic review","volume":"10","author":"Cerritelli F","year":"2017","unstructured":"Cerritelli F\n\n, \n\nLacorte E\n\n, \n\nRuffini N\n\n, \n\nVanacore N\n\n\n. \nOsteopathy for primary headache patients: a systematic review\n. \nJ Pain Res\n. \n2017\n; \n10:601\u2013611\n. \n\n10.2147\/JPR.S130501"},{"issue":"12","key":"B2","series-title":"Cureus","first-page":"e12040","article-title":"Osteopathic manipulative treatment in tension headaches","volume":"12","author":"Chin J","year":"2020","unstructured":"Chin J\n\n, \n\nQiu W\n\n, \n\nLomiguen CM\n\n, \n\nVolokitin M\n\n\n. \nOsteopathic manipulative treatment in tension headaches\n. \nCureus\n. \n2020\n; \n12(12):e12040."},{"key":"B3","unstructured":"Cleveland Clinic. 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Available from \n\nhttps:\/\/www.faa.gov\/ame_guide\n."},{"issue":"2","key":"B5","series-title":"Aviat Space Environ Med","first-page":"115","article-title":"A questionnaire for the assessment of the multiple dimensions of motion sickness","volume":"72","author":"Gianaros PJ","year":"2001","unstructured":"Gianaros PJ\n\n, \n\nMuth ER\n\n, \n\nMordkoff JT\n\n, \n\nLevine ME\n\n, \n\nStern RM\n\n\n. \nA questionnaire for the assessment of the multiple dimensions of motion sickness\n. \nAviat Space Environ Med\n. \n2001\n; \n72(2):115\u2013119."},{"key":"B6","series-title":"A literature review of potential countermeasures for motion sickness in soldiers transported by future vertical lift","author":"Goldie C","year":"2022","unstructured":"Goldie C\n\n, \n\nGaydos S\n\n\n. \nA literature review of potential countermeasures for motion sickness in soldiers transported by future vertical lift\n. \nFt. Rucker (AL)\n: \nU.S. Army Aeromedical Research Laboratory\n; \n2022\n. Report No.: USAARL-TECH-FR\u20132022-08."},{"key":"B7","series-title":"Handb Clin Neurol","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/B978-0-444-63437-5.00027-3","article-title":"Motion sickness","volume":"137","author":"Golding JF","year":"2016","unstructured":"Golding JF\n\n\n. \nMotion sickness\n. \nHandb Clin Neurol\n. \n2016\n; \n137:371\u2013390\n. \n\n10.1016\/B978-0-444-63437-5.00027-3"},{"issue":"5","key":"B8","series-title":"Brain Res Bull","first-page":"507","article-title":"Motion sickness susceptibility questionnaire revised and its relationship to other forms of sickness","volume":"47","author":"Golding JF","year":"1998","unstructured":"Golding JF\n\n\n. \nMotion sickness susceptibility questionnaire revised and its relationship to other forms of sickness\n. \nBrain Res Bull\n. \n1998\n; \n47(5):507\u2013516\n. \n\n10.1016\/S0361-9230(98)00091-4"},{"key":"B9","series-title":"Drugs Context","article-title":"Motion sickness: an overview","volume":"8","author":"Leung AK","year":"2019","unstructured":"Leung AK\n\n, \n\nHon KL\n\n\n. \nMotion sickness: an overview\n. \nDrugs Context\n. \n2019\n; \n8:2019-9-4."},{"issue":"5","key":"B10","series-title":"Ther Drug Monit","first-page":"655","article-title":"Pharmacokinetics and pharmacodynamics in clinical use of scopolamine","volume":"27","author":"Renner UD","year":"2005","unstructured":"Renner UD\n\n, \n\nOertel R\n\n, \n\nKirch W\n\n\n. \nPharmacokinetics and pharmacodynamics in clinical use of scopolamine\n. \nTher Drug Monit\n. \n2005\n; \n27(5):655\u2013665\n. \n\n10.1097\/01.ftd.0000168293.48226.57"},{"key":"B11","first-page":"3306","author":"Russomano T","year":"2003","unstructured":"Russomano T\n\n, \n\nde Azevedo DF\n\n, \n\nPiedade L\n\n, \n\nGlock FS\n\n, \n\nTello M\n\n, \n\n Development and validation of an electrically controlled rotatory chair to be used as a simulator for spatial disorientation and motion sickness. 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