{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:52:13Z","timestamp":1793379133534,"version":"4.5.0"},"reference-count":25,"publisher":"Aerospace Medical Association","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p><jats:bold>INTRODUCTION:<\/jats:bold> Habituation to motion has therapeutic applications for motion sickness desensitization and rehabilitation of patients with vestibular disease. Less attention has been devoted to the opposite process: sensitization.<\/jats:p>\n<jats:p><jats:bold>METHODS:<\/jats:bold> Subjects (<jats:italic>N<\/jats:italic> = 50) were randomly allocated to four sequences: Baseline visual stimulus; then 15\u2009min of time gap; cross-coupled motion (C-C) or a Control condition; then a time gap of 15\u2009min or 2\u2009h; then a retest visual stimulus. Motion exposures were for 10\u2009min or until moderate nausea, whichever was sooner. The visual stimulus was a scene rotating in yaw at 0.2\u2009Hz with superimposed \"wobble\". C-C was whole-body rotation on a turntable with eight 45\u00b0 head tilts during each 30-s period. Control was head tilt without rotation. Rotational velocity was incremented in staircase steps of 3\u00b0 \u00b7 s<jats:sup>\u22121<\/jats:sup> every 30\u2009s.<\/jats:p>\n<jats:p><jats:bold>RESULTS:<\/jats:bold> Groups were equivalent for Total Motion Sickness Symptom scores elicited by the first visual stimulus (combined: mean \u00b1 SD 10.8\u2009\u00b1\u20098.4). C-C produced greater Total Symptoms (20.3\u2009\u00b1\u20096.8) than Control (3.1\u2009\u00b1\u20093.7). Subjects recovered subjectively from C-C before retest of visual stimulus. For the retest visual stimulus, Total Symptoms were higher following C-C (15.1\u2009\u00b1\u20099.0) than following Control (8.3\u2009\u00b1\u20097.1) for both the 15\u2009min and 2\u2009h retests. Sickness ratings (SR) mirrored these effects of C-C.<\/jats:p>\n<jats:p><jats:bold>DISCUSSION:<\/jats:bold> C-C motion sensitized subsequent responses to visual stimulation up to 2\u2009h later. Sensitization of visual stimulation crossed modalities and appeared subconscious since it occurred despite subjective recovery from C-C. For some individuals, a previously relatively innocuous visual stimulus became nauseogenic on retest. The results have implications for the use of visual technologies within hours of exposure to provocative motion.<\/jats:p>\n<jats:p><jats:bold>Golding JF, Alund D, Gresty MA, Flynn MB. <jats:italic>Sensitization of visually induced motion sickness by prior provocative physical motion<\/jats:italic>. Aerosp Med Hum Perform. 2024; 95(10):741\u2013748.<\/jats:bold><\/jats:p>","DOI":"10.3357\/amhp.6481.2024","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T00:31:12Z","timestamp":1729125072000},"page":"741-748","source":"Crossref","is-referenced-by-count":3,"title":["Sensitization of Visually Induced Motion Sickness by Prior Provocative Physical Motion"],"prefix":"10.3357","volume":"95","author":[{"given":"John F.","family":"Golding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Alund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Gresty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria B.","family":"Flynn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1911","reference":[{"key":"B1","series-title":"Ernsting\u2019s aviation and space medicine.","first-page":"781","article-title":"Motion sickness","author":"Benson AJ","year":"2016","unstructured":"Benson AJ, Stott JRR. 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