{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:56:54Z","timestamp":1791928614555,"version":"4.3.4"},"reference-count":22,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T00:00:00Z","timestamp":1570147200000},"content-version":"vor","delay-in-days":733,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.3382\/ps\/pex164","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T11:33:56Z","timestamp":1497958436000},"page":"3581-3585","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Impact of a Macleaya cordata-derived alkaloid extract on necrotic enteritis in broilers"],"prefix":"10.1016","volume":"96","author":[{"given":"G.D.","family":"Xue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.B.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Choct","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Pastor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.A.","family":"Swick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.3382\/ps\/pex164_bib1","unstructured":"Aviagen, 2014. Broiler Nutrition Specification Ross 308. Huntsville, Alabama, USA."},{"key":"10.3382\/ps\/pex164_bib2","doi-asserted-by":"crossref","first-page":"617","DOI":"10.2307\/1590433","article-title":"Necrotic enteritis in cage-reared commercial layer pullets","volume":"30","author":"Broussard","year":"1986","journal-title":"Avian Dis"},{"key":"10.3382\/ps\/pex164_bib3","doi-asserted-by":"crossref","first-page":"30129","DOI":"10.1074\/jbc.272.48.30129","article-title":"Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-\u03baB activation, I\u03baBa phosphorylation, and degradation","volume":"272","author":"Chaturvedi","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.3382\/ps\/pex164_bib4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.vetimm.2006.07.007","article-title":"Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections","volume":"114","author":"Hong","year":"2006","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.3382\/ps\/pex164_bib5","first-page":"279","article-title":"Efficacy of the phytogenic (Papaveraceae) additive Sangrovit\u00ae in growing monogastric animals","volume":"81","author":"Jeroch","year":"2009","journal-title":"Z\u00fcchtungskunde"},{"key":"10.3382\/ps\/pex164_bib6","series-title":"Physiological and Ecological Adaptations to Feeding in Vertebrates","first-page":"229","article-title":"Interplay between diet, microbes, and immune defenses of the gastrointestinal tract","author":"Klasing","year":"2005"},{"key":"10.3382\/ps\/pex164_bib7","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1093\/jn\/117.9.1629","article-title":"Immunologically mediated growth depression in chicks: influence of feed intake, corticosterone and interleukin-1","volume":"117","author":"Klasing","year":"1987","journal-title":"J. Nutr."},{"key":"10.3382\/ps\/pex164_bib8","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1753-4887.1990.tb02967.x","article-title":"Is glutamine a conditionally essential amino acid?","volume":"48","author":"Lacey","year":"1990","journal-title":"Nutr. Rev"},{"key":"10.3382\/ps\/pex164_bib9","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.3382\/ps.2010-01319","article-title":"Avian necrotic enteritis: Experimental models, host immunity, pathogenesis, risk factors, and vaccine development","volume":"90","author":"Lee","year":"2011","journal-title":"Poult. Sci."},{"key":"10.3382\/ps\/pex164_bib10","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1637\/7054","article-title":"Nitric oxide production by macrophages stimulated with coccidia sporozoites, lipopolysaccharide, or interferon-\u03b3, and its dynamic changes in SC and TK strains of chickens infected with Eimeria tenella","volume":"48","author":"Lillehoj","year":"2004","journal-title":"Avian Dis"},{"key":"10.3382\/ps\/pex164_bib11","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.3382\/ps\/pev219","article-title":"Dietary acylated starch improves performance and gut health in necrotic enteritis challenged broilers","volume":"94","author":"M\u2019Sadeq","year":"2015","journal-title":"Poult. Sci."},{"key":"10.3382\/ps\/pex164_bib12","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1098\/rspb.2002.2185","article-title":"Immune activity elevates energy expenditure of house sparrows: a link between direct and indirect costs?","volume":"270","author":"Martin","year":"2003","journal-title":"Proc. Biol. Sci."},{"key":"10.3382\/ps\/pex164_bib13","unstructured":"Niewold T. A., Backer, K. D., 2010. The in vitro anti-inflammatory property of sanguinarine containing extracts is consistent with enhanced in vivo performance in production animals. Proc. 13th European Poultry Conference, France."},{"key":"10.3382\/ps\/pex164_bib14","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.ejphar.2012.05.039","article-title":"The anti-inflammatory effects of sanguinarine and its modulation of inflammatory mediators from peritoneal macrophages","volume":"689","author":"Niu","year":"2012","journal-title":"Eur. J. Pharmacol."},{"key":"10.3382\/ps\/pex164_bib15","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.rvsc.2005.10.006","article-title":"Responses of broiler chickens orally challenged with Clostridium perfringens isolated from field cases of necrotic enteritis","volume":"81","author":"Olkowski","year":"2006","journal-title":"Res. Vet. Sci."},{"key":"10.3382\/ps\/pex164_bib16","first-page":"181","article-title":"The use of bacitracin in the prevention and treatment of experimentally-induced necrotic enteritis in the chicken","volume":"19","author":"Prescott","year":"1978","journal-title":"Can. Vet. J."},{"key":"10.3382\/ps\/pex164_bib17","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/1297-9716-43-74","article-title":"The successful experimental induction of necrotic enteritis in chickens by Clostridium perfringens: a critical review","volume":"43","author":"Shojadoost","year":"2012","journal-title":"Vet. Res."},{"key":"10.3382\/ps\/pex164_bib18","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3382\/japr.2007-00054","article-title":"Performance of broilers fed diets supplemented with sanguinarine-like alkaloids and organic acids","volume":"17","author":"Vieira","year":"2008","journal-title":"J. Appl. Poult. Res."},{"key":"10.3382\/ps\/pex164_bib19","doi-asserted-by":"crossref","first-page":"3256","DOI":"10.2527\/jas.2007-0320","article-title":"Enterocyte proliferation and apoptosis in the caudal small intestine is influenced by the composition of colonizing commensal bacteria in the neonatal gnotobiotic pig","volume":"85","author":"Willing","year":"2007","journal-title":"J. Anim. Sci."},{"key":"10.3382\/ps\/pex164_bib20","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1042\/bj2740769","article-title":"Glutamine metabolism in skeletal muscles from the broiler chick (Gallus domesticus) and the laboratory rat (Rattus norvegicus)","volume":"274","author":"Wu","year":"1991","journal-title":"Biochem. J."},{"key":"10.3382\/ps\/pex164_bib21","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/cr.2010.175","article-title":"NF-\u03baB in the regulation of epithelial homeostasis and inflammation","volume":"21","author":"Wullaert","year":"2011","journal-title":"Cell Res"},{"key":"10.3382\/ps\/pex164_bib22","doi-asserted-by":"crossref","first-page":"G496","DOI":"10.1152\/ajpgi.00318.2005","article-title":"Molecular mechanism of tumor necrosis factor-a modulation of intestinal epithelial tight junction barrier","volume":"290","author":"Ye","year":"2006","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119315718?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119315718?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ps\/article-pdf\/96\/10\/3581\/19921483\/pex164.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T20:43:05Z","timestamp":1758487385000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579119315718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0032579119315718"],"URL":"https:\/\/doi.org\/10.3382\/ps\/pex164","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of a Macleaya cordata-derived alkaloid extract on necrotic enteritis in broilers","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3382\/ps\/pex164","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 Poultry Science Association Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}