{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:30:54Z","timestamp":1790908254210,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,15]],"date-time":"2019-10-15T00:00:00Z","timestamp":1571097600000},"content-version":"vor","delay-in-days":3666,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.3382\/ps.2009-00076","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T20:40:56Z","timestamp":1253220056000},"page":"2069-2074","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":68,"title":["Serum ovotransferrin as a biomarker of inflammatory diseases in chickens"],"prefix":"10.1016","volume":"88","author":[{"given":"N.C.","family":"Rath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.B.","family":"Anthony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Kannan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.E.","family":"Huff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.R.","family":"Huff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.D.","family":"Chapman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.F.","family":"Erf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Wakenell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.3382\/ps.2009-00076_bib1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1139\/o01-153","article-title":"Lactoferrin and transferrin: Functional variations on a common structural framework","volume":"80","author":"Baker","year":"2002","journal-title":"Biochem. Cell Biol."},{"key":"10.3382\/ps.2009-00076_bib2","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/ps\/79.3.318","article-title":"Ascites syndrome and related pathologies in feed restricted broilers raised in a hypobaric chamber","volume":"79","author":"Balog","year":"2000","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/0167-5699(94)90137-6","article-title":"The acute phase response","volume":"15","author":"Baumann","year":"1994","journal-title":"Immunol. Today"},{"key":"10.3382\/ps.2009-00076_bib4","author":"CDER"},{"key":"10.3382\/ps.2009-00076_bib5","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1078\/S0171-9335(04)70018-7","article-title":"Extracellular fatty acid binding protein (Ex-FABP) modulation by inflammatory agents: \u201cPhysiological\u201d acute phase response in endochondral bone formation","volume":"79","author":"Cermelli","year":"2000","journal-title":"Eur. J. Cell Biol."},{"key":"10.3382\/ps.2009-00076_bib6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1079\/WPS19990005","article-title":"Acute phase proteins in domestic fowl","volume":"55","author":"Chamanza","year":"1999","journal-title":"World\u2019s Poult. Sci. J."},{"key":"10.3382\/ps.2009-00076_bib7","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/ps\/83.5.761","article-title":"The effects of salinomycin and roxarsone on the performance of broilers when included in the feed for four, five, or six weeks and infected with Eimeria species during the starter or grower phase of production","volume":"83","author":"Chapman","year":"2004","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib8","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.cbpb.2006.03.003","article-title":"Isolation, cloning and sequencing of transferrins from red-eared turtle, African ostrich, and turkey","volume":"144","author":"Ciuraszkiewicz","year":"2006","journal-title":"Comp. Biochem. Physiol. Biochem. Mol. Biol."},{"key":"10.3382\/ps.2009-00076_bib9","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1637\/8367-051908-Reg.1","article-title":"Histopathology and serum clinical chemistry evaluation of broilers with femoral head separation disorder","volume":"53","author":"Durairaj","year":"2009","journal-title":"Avian Dis."},{"key":"10.3382\/ps.2009-00076_bib10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S1090-0233(03)00165-5","article-title":"The time is right for acute phase protein assays","volume":"168","author":"Eckersall","year":"2004","journal-title":"Vet. J."},{"key":"10.3382\/ps.2009-00076_bib11","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.proghi.2007.06.001","article-title":"Regulation of angiogenesis: Wound healing as a model","volume":"42","author":"Eming","year":"2007","journal-title":"Prog. Histochem. Cytochem."},{"key":"10.3382\/ps.2009-00076_bib12","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1056\/NEJM199902113400607","article-title":"Acute-phase proteins and other systemic responses to inflammation","volume":"340","author":"Gabay","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.3382\/ps.2009-00076_bib13","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1139\/o06-210","article-title":"Ovotransferrin expression and release by chicken cell lines infected with Marek\u2019s disease virus","volume":"85","author":"Giansanti","year":"2007","journal-title":"Biochem. Cell Biol."},{"key":"10.3382\/ps.2009-00076_bib14","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.acthis.2006.03.009","article-title":"Monitoring health by values of acute phase proteins","volume":"108","author":"Gruys","year":"2006","journal-title":"Acta Histochem."},{"key":"10.3382\/ps.2009-00076_bib15","first-page":"375","article-title":"Serotransferrin, ovotransferrin and metallothionein levels during an immune response in chickens","volume":"108","author":"Hallquist","year":"1994","journal-title":"Comp. Biochem. Physiol."},{"key":"10.3382\/ps.2009-00076_bib16","series-title":"Antibodies, A Laboratory Manual","first-page":"471","article-title":"Immunoblotting","author":"Harlow","year":"1988"},{"key":"10.3382\/ps.2009-00076_bib17","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1093\/ps\/81.9.1295","article-title":"Comparison of the effects of infection with Salmonella Enteritidis, in combination with an induced molt, on serum levels of the acute phase protein \u03b11-acid glycoprotein, in hens","volume":"81","author":"Holt","year":"2000","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib18","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1093\/ps\/85.8.1373","article-title":"Evaluation of the influence of bacteriophage titer on the treatment of colibacillosis in broiler chickens","volume":"85","author":"Huff","year":"2006","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib19","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/ps\/82.2.235","article-title":"Serum levels of mannan-binding lectin (MBL) in chickens prior to and during experimental infection with avian infectious bronchitis virus (IBV)","volume":"82","author":"Juul-Madsen","year":"2003","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib20","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1093\/ps\/76.10.1355","article-title":"Dietary fish oil or lofrin, a 5-lipoxygenase inhibitor, decrease the growth-suppressing effects of coccidiosis in broiler chicks","volume":"76","author":"Korver","year":"1997","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib21","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.cbpb.2005.07.007","article-title":"Evolution of the transferrin family: Conservation of residues associated with iron and anion binding","volume":"142","author":"Lambert","year":"2005","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.3382\/ps.2009-00076_bib22","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S1090-0233(03)00119-9","article-title":"Current research on acute phase proteins in veterinary diagnosis: An overview","volume":"168","author":"Murata","year":"2004","journal-title":"Vet. J."},{"key":"10.3382\/ps.2009-00076_bib23","author":"NCGC"},{"key":"10.3382\/ps.2009-00076_bib24","series-title":"Nutrient Requirements of Poultry","author":"NRC","year":"1994"},{"key":"10.3382\/ps.2009-00076_bib25","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1093\/ps\/79.4.580","article-title":"Extraction and quantification by ELISA of eggshell organic matrix proteins (ovocleidin-17, ovalbumin, ovotransferrin) in shell from young and old hens","volume":"79","author":"Panheleux","year":"2000","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib26","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.3382\/ps.2007-00134","article-title":"Divergent selection for ascites incidence in chickens","volume":"86","author":"Pavlidis","year":"2007","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib27","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1051\/vetres:2004002","article-title":"Application of acute phase protein measurements in veterinary clinical chemistry","volume":"35","author":"Petersen","year":"2004","journal-title":"Vet. Res."},{"key":"10.3382\/ps.2009-00076_bib28","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/ps\/83.2.266","article-title":"Comparative efficacy of different dithiocarbamates to induce tibial dyschondroplasia in poultry","volume":"83","author":"Rath","year":"2004","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib29","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1637\/0005-2086(2007)51[590:IOTDBC]2.0.CO;2","article-title":"Induction of tibial dyschondroplasia by carbamate and thiocarbamate pesticides","volume":"51","author":"Rath","year":"2007","journal-title":"Avian Dis."},{"key":"10.3382\/ps.2009-00076_bib30","series-title":"New Immunology Research Development","first-page":"95","article-title":"Avian acute phase protein ovotransferrin modulates phagocyte function","author":"Rath","year":"2008"},{"key":"10.3382\/ps.2009-00076_bib31","series-title":"SAS\/ STAT\u00ae User\u2019s Guide","author":"SAS Institute","year":"2004"},{"key":"10.3382\/ps.2009-00076_bib32","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1023\/A:1020563913045","article-title":"New insights into the biology of the acute phase response","volume":"19","author":"Suffredini","year":"1999","journal-title":"J. Clin. Immunol."},{"key":"10.3382\/ps.2009-00076_bib33","series-title":"Bioacive Egg Compounds","first-page":"43","article-title":"Ovotransferrin","author":"Superti","year":"2007"},{"key":"10.3382\/ps.2009-00076_bib34","doi-asserted-by":"crossref","first-page":"3771","DOI":"10.1016\/S0021-9258(17)34753-1","article-title":"Identical precursors for serum transferrin and egg white conalbumin","volume":"253","author":"Thibodeau","year":"1978","journal-title":"J. Biol. Chem."},{"key":"10.3382\/ps.2009-00076_bib35","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jaci.2005.05.036","article-title":"Innate immune responses to infection","volume":"116","author":"Tosi","year":"2005","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.3382\/ps.2009-00076_bib37","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jaut.2003.09.006","article-title":"Apoptosis in feathers of Smyth line chickens with autoimmune vitiligo","volume":"22","author":"Wang","year":"2004","journal-title":"J. Autoimmun."},{"key":"10.3382\/ps.2009-00076_bib38","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0065-2776(06)92002-1","article-title":"Avian models with spontaneous autoimmune diseases","volume":"92","author":"Wick","year":"2006","journal-title":"Adv. Immunol."},{"key":"10.3382\/ps.2009-00076_bib39","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1093\/ps\/81.1.112","article-title":"Identification of ovotransferrin as an acute phase protein in chickens","volume":"81","author":"Xie","year":"2002","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2009-00076_bib40","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0145-305X(02)00028-9","article-title":"Effects of ovotransferrin on chicken macrophages and heterophil-granulocytes","volume":"26","author":"Xie","year":"2003","journal-title":"Dev. Comp. Immunol."},{"key":"10.3382\/ps.2009-00076_bib41","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1637\/0005-2086(2002)046[0122:CISOLI]2.0.CO;2","article-title":"Changes in serum ovotransferrin levels in chickens with experimentally induced inflammation and diseases","volume":"46","author":"Xie","year":"2002","journal-title":"Avian Dis."},{"issue":"Suppl. A","key":"10.3382\/ps.2009-00076_bib36","doi-asserted-by":"crossref","first-page":"A39","DOI":"10.1016\/j.jvs.2007.02.068","article-title":"Angiogenesis and vasculogenesis: Inducing the growth of new blood vessels and wound healing by stimulation of bone marrow-derived progenitor cell mobilization and homing","volume":"45","author":"Velazquez","year":"2007","journal-title":"J. Vasc. Surg."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119404525?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119404525?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ps\/article-pdf\/88\/10\/2069\/4465351\/poultrysci88-2069.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T21:19:52Z","timestamp":1758489592000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579119404525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0032579119404525"],"URL":"https:\/\/doi.org\/10.3382\/ps.2009-00076","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serum ovotransferrin as a biomarker of inflammatory diseases in chickens","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3382\/ps.2009-00076","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Poultry Science Association Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}