{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T09:22:34Z","timestamp":1772184154155,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T00:00:00Z","timestamp":1570147200000},"content-version":"vor","delay-in-days":1951,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.3382\/ps.2013-03840","type":"journal-article","created":{"date-parts":[[2014,5,30]],"date-time":"2014-05-30T10:24:44Z","timestamp":1401445484000},"page":"1368-1374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Rosiglitazone modulates pigeon atherosclerotic lipid accumulation and gene expression in vitro"],"prefix":"10.1016","volume":"93","author":[{"given":"J.L.","family":"Anderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.C.","family":"Keeley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.C.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.C.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"R.L.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.3382\/ps.2013-03840_bib1","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.3382\/ps.2013-03306","article-title":"Atherosclerosis-susceptible and atherosclerosis-resistant pigeon aortic cells express different genes in vivo","volume":"92","author":"Anderson","year":"2013","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2013-03840_bib2","unstructured":"Anderson, J. L., S. C. Smith, and R. L. Taylor Jr. 2011. Spontaneous atherosclerosis in pigeons: A good model of human disease. Pages 25\u201348 in Atherogenesis. S. Parthasarathy, ed. InTech Inc., Rijeka, Croatia. Accessed Jan. 11, 2012. http:\/\/www.intechopen.com\/articles\/show\/title\/spontaneous-atherosclerosis-in-pigeons-a-good-model-of-human-disease"},{"key":"10.3382\/ps.2013-03840_bib3","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.3382\/ps.2011-01975","article-title":"Differentially expressed genes in aortic smooth muscle cells from atherosclerosis-susceptible and atherosclerosis-resistant pigeons","volume":"91","author":"Anderson","year":"2012","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2013-03840_bib4","doi-asserted-by":"crossref","first-page":"3888","DOI":"10.1038\/sj.onc.1206625","article-title":"Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells","volume":"22","author":"Burgermeister","year":"2003","journal-title":"Oncogene"},{"key":"10.3382\/ps.2013-03840_bib5","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1161\/01.ATV.0000177813.99577.6b","article-title":"Rosiglitazone attenuates atherosclerosis in a model of insulin insufficiency independent of its metabolic effects","volume":"25","author":"Calkin","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.3382\/ps.2013-03840_bib6","first-page":"6571","article-title":"Role of caveolae and lipid rafts in cancer: Workshop summary and future needs","volume":"63","author":"Carver","year":"2003","journal-title":"Cancer Res."},{"key":"10.3382\/ps.2013-03840_bib7","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1161\/01.ATV.21.3.372","article-title":"Troglitazone inhibits atherosclerosis in apolipoprotein E\u2013knockout mice: Pleiotropic effects on CD36 expression and HDL","volume":"21","author":"Chen","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.3382\/ps.2013-03840_bib8","first-page":"143","article-title":"Atherosclerosis in pigeons: Its spontaneous occurrence and resemblance to human atherosclerosis","volume":"68","author":"Clarkson","year":"1959","journal-title":"AMA Arch. Pathol."},{"key":"10.3382\/ps.2013-03840_bib9","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1152\/physrev.00046.2003","article-title":"Role of caveolae and caveolins in health and disease","volume":"84","author":"Cohen","year":"2004","journal-title":"Physiol. Rev."},{"key":"10.3382\/ps.2013-03840_bib10","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1093\/jn\/106.5.627","article-title":"Yolk lipids of developing atherosclerosis-susceptible White Carneau and atherosclerosis-resistant Show Racer pigeon embryos","volume":"106","author":"Cramer","year":"1976","journal-title":"J. Nutr."},{"key":"10.3382\/ps.2013-03840_bib11","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1006\/excr.1999.4686","article-title":"Function of the c-myc oncongenic transcription factor","volume":"253","author":"Dang","year":"1999","journal-title":"Exp. Cell Res."},{"key":"10.3382\/ps.2013-03840_bib12","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/01.ATV.0000101182.89118.E5","article-title":"Genetic ablation of caveolin-1 confers protection against atherosclerosis","volume":"24","author":"Frank","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.3382\/ps.2013-03840_bib13","first-page":"683","article-title":"Lipid accumulation and ultrastructural change within the aortic wall during early spontaneous atherogenesis","volume":"100","author":"Hajjar","year":"1980","journal-title":"Am. J. Pathol."},{"key":"10.3382\/ps.2013-03840_bib14","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1161\/hq1201.100261","article-title":"PPAR? and atherosclerosis: Effects on cell growth and movement","volume":"21","author":"Hsueh","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.3382\/ps.2013-03840_bib15","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1093\/ps\/86.6.1166","article-title":"Expression of cell-cycle-regulating genes in the development of atherosclerosis in Japanese quail","volume":"86","author":"Inafuku","year":"2007","journal-title":"Poult. Sci."},{"key":"10.3382\/ps.2013-03840_bib16","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1093\/nar\/26.10.2420","article-title":"c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of a-smooth muscle actin gene in chicken visceral smooth muscle cells","volume":"26","author":"Kimura","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"10.3382\/ps.2013-03840_bib17","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1210\/en.2003-0288","article-title":"Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors","volume":"144","author":"Lee","year":"2003","journal-title":"Endocrinology"},{"key":"10.3382\/ps.2013-03840_bib18","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1161\/01.ATV.0000109170.43400.2f","article-title":"Interferon regulatory factor-1 mediates PPAR?-induced apoptosis in vascular smooth muscle cells","volume":"24","author":"Lin","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.3382\/ps.2013-03840_bib19","doi-asserted-by":"crossref","first-page":"3683","DOI":"10.1182\/blood-2005-05-2103","article-title":"Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPAR a\/? ligand TZD18","volume":"107","author":"Liu","year":"2006","journal-title":"Blood"},{"key":"10.3382\/ps.2013-03840_bib20","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.2165\/00003495-200262100-00004","article-title":"Metabolic and additional effects of thiazolidinediones","volume":"62","author":"Martens","year":"2002","journal-title":"Drugs"},{"key":"10.3382\/ps.2013-03840_bib21","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1161\/01.RES.0000127122.22685.0A","article-title":"Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells","volume":"94","author":"Marx","year":"2004","journal-title":"Circ. Res."},{"key":"10.3382\/ps.2013-03840_bib22","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1038\/labinvest.3780331","article-title":"Advances in experimental dyslipidemia and atherosclerosis","volume":"81","author":"Moghadasian","year":"2001","journal-title":"Lab. Invest."},{"key":"10.3382\/ps.2013-03840_bib23","first-page":"147","article-title":"Balance between fatty acid degradation and lipid accumulation in cultured smooth muscles cells and IC-21 macrophages exposed to oleic acid","volume":"98B","author":"Moinet","year":"1991","journal-title":"Comp. Biochem. Physiol."},{"key":"10.3382\/ps.2013-03840_bib24","unstructured":"Morgan, D. 2013. FDA panel revisits Avandia, likely too late for diabetic drug. Accessed Dec. 1, 2013. http:\/\/www.reuters.com\/article\/2013\/06\/05"},{"key":"10.3382\/ps.2013-03840_bib25","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0014-5793(01)02118-4","article-title":"Making decisions through myc","volume":"490","author":"Nasi","year":"2001","journal-title":"FEBS Lett."},{"key":"10.3382\/ps.2013-03840_bib26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0014-4800(72)90055-X","article-title":"Lipid accumulation in muscular foci in White Carneau and Show Racer pigeon aortas","volume":"17","author":"Nicolosi","year":"1972","journal-title":"Exp. Mol. Pathol."},{"key":"10.3382\/ps.2013-03840_bib27","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1365-2443.2000.00311.x","article-title":"MSSP promotes ras\/myc cooperative cell transforming activity by binding to c-myc","volume":"5","author":"Niki","year":"2000","journal-title":"Genes Cells"},{"key":"10.3382\/ps.2013-03840_bib28","doi-asserted-by":"crossref","first-page":"616","DOI":"10.2337\/diabetes.48.3.616","article-title":"Fatty acids modulate the composition of extracellular matrix in cultured human arterial smooth muscle cells by altering the expression of genes for proteoglycan core proteins","volume":"48","author":"Olsson","year":"1999","journal-title":"Diabetes"},{"key":"10.3382\/ps.2013-03840_bib29","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1006\/abio.2000.4622","article-title":"Optimization of cDNA representational difference analysis for the identification of differentially expressed mRNAs","volume":"283","author":"Pastorian","year":"2000","journal-title":"Anal. Biochem."},{"key":"10.3382\/ps.2013-03840_bib30","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.atherosclerosis.2004.12.033","article-title":"Low-density lipoprotein non-esterified fatty acids and lipoprotein lipase in diabetes","volume":"181","author":"Phillips","year":"2005","journal-title":"Atherosclerosis"},{"key":"10.3382\/ps.2013-03840_bib31","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1097\/MOL.0b013e3282ef534f","article-title":"Fatty acid-induced atherogenic changes in extracellular matrix proteoglycans","volume":"18","author":"Rodrigu\u00e9z -Lee","year":"2007","journal-title":"Curr. Opin. Lipidol."},{"key":"10.3382\/ps.2013-03840_bib32","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1146\/annurev.nutr.25.051804.101917","article-title":"Polyunsaturated fatty acid regulation of genes of lipid metabolism","volume":"25","author":"Sampath","year":"2005","journal-title":"Annu. Rev. Nutr."},{"key":"10.3382\/ps.2013-03840_bib33","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1161\/01.CIR.88.3.1190","article-title":"Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells","volume":"88","author":"Shi","year":"1993","journal-title":"Circulation"},{"key":"10.3382\/ps.2013-03840_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0002466","article-title":"Pioglititzone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome","volume":"3","author":"Skov","year":"2008","journal-title":"PLoS ONE"},{"key":"10.3382\/ps.2013-03840_bib35","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/jhered\/92.5.439","article-title":"Susceptibility to spontaneous atherosclerosis in pigeons: An autosomal recessive trait","volume":"92","author":"Smith","year":"2001","journal-title":"J. Hered."},{"key":"10.3382\/ps.2013-03840_bib36","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0368-1319(65)80073-4","article-title":"Fatty acid composition of cultured aortic smooth muscle cells from White Carneau and Show Racer pigeons","volume":"5","author":"Smith","year":"1965","journal-title":"J. Atheroscler. Res."},{"key":"10.3382\/ps.2013-03840_bib37","first-page":"2480","article-title":"Metabolic changes in the arterial wall associated with atherosclerosis in the pigeon","volume":"42","author":"St. Clair","year":"1983","journal-title":"Fed. Proc."},{"key":"10.3382\/ps.2013-03840_bib38","doi-asserted-by":"crossref","first-page":"5958","DOI":"10.1074\/jbc.275.8.5958","article-title":"Structural analysis of a-enolase: Mapping the functional domains involved in down-regulation of the c-myc protooncogene","volume":"275","author":"Subramanian","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.3382\/ps.2013-03840_bib39","series-title":"Methods in Molecular Medicine","first-page":"83","article-title":"Use of cDNA representational difference analysis to identify disease specific genes in human atherosclerosis","author":"Tyson","year":"2000"},{"key":"10.3382\/ps.2013-03840_bib40","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1161\/01.ATV.0000127311.38703.1f","article-title":"PPAR-gamma agonists: Shifting attention from the belly to the heart?","volume":"24","author":"van Wijk","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119323090?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579119323090?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ps\/article-pdf\/93\/6\/1368\/4455029\/1368.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T20:50:29Z","timestamp":1758487829000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579119323090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S0032579119323090"],"URL":"https:\/\/doi.org\/10.3382\/ps.2013-03840","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rosiglitazone modulates pigeon atherosclerotic lipid accumulation and gene expression in vitro","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.3382\/ps.2013-03840","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Poultry Science Association Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}