{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T16:53:53Z","timestamp":1780592033703,"version":"3.54.1"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioinform."],"abstract":"<jats:p>Genomic and metagenomic sequence data provides an unprecedented ability to re-examine findings, offering a transformative potential for advancing research, developing computational tools, enhancing clinical applications, and fostering scientific collaboration. However, effective and ethical reuse of genomics data is hampered by numerous technical and social challenges. The International Microbiome and Multi\u2019Omics Standards Alliance (IMMSA, <jats:ext-link>https:\/\/www.microbialstandards.org\/<\/jats:ext-link>) and the Genomic Standards Consortium (GSC, <jats:ext-link>https:\/\/gensc.org<\/jats:ext-link>) hosted a 5-part seminar series \u201cA Year of Data Reuse\u201d in 2024 to explore challenges and opportunities of data reuse and reproducibility across disparate domains of the genomic sciences. Addressing these challenges will require a multifaceted approach, including common metadata reporting, clear communication, standardized protocols, improved data management infrastructure, ethical guidelines, and collaborative policies that prioritize transparency and accessibility. We offer strategies to enable responsible and technically feasible data reuse, recognition of data reproducibility challenges, and emphasizing the importance of cross-disciplinary efforts in the pursuit of open science and data-driven innovation.<\/jats:p>","DOI":"10.3389\/fbinf.2025.1572937","type":"journal-article","created":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T06:48:16Z","timestamp":1741589296000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["A standards perspective on genomic data reusability and reproducibility"],"prefix":"10.3389","volume":"5","author":[{"given":"Ishi","family":"Keenum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott A.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiley","family":"Eloe-Fadrosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn M.","family":"Schriml","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,3,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"eadi1910","DOI":"10.1126\/science.adi1910","article-title":"Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering","volume":"382","author":"Altae-Tran","year":"2023","journal-title":"Science"},{"key":"B2","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1126\/science.aaw1280","article-title":"Toward unrestricted use of public genomic data","volume":"363","author":"Amann","year":"2019","journal-title":"Science"},{"key":"B3","doi-asserted-by":"publisher","first-page":"926","DOI":"10.12688\/f1000research.134798.2","article-title":"Facilitating accessible, rapid, and appropriate processing of ancient metagenomic data with AMDirT","volume":"12","author":"Borry","year":"2024","journal-title":"F1000Research"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1038\/s41597-024-04049-7","article-title":"Identifying genomic data use with the data citation explorer","volume":"11","author":"Byers","year":"2024","journal-title":"Sci. data"},{"key":"B5","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1038\/s41586-018-0207-y","article-title":"Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis","volume":"558","author":"Crits-Christoph","year":"2018","journal-title":"Nature"},{"key":"B6","doi-asserted-by":"publisher","first-page":"e0126123","DOI":"10.1128\/mra.01261-23","article-title":"The virome of the kitome: small circular virus-like genomes in laboratory reagents","volume":"13","author":"Duan","year":"2024","journal-title":"Microbiol. 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