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With respect to the microbial community, the genomic signatures of each bacterium are unique to that bacterium; they do not exist in other bacteria in the community. Further, since the genomic signatures of a bacterium are much smaller than its genome size, the approach allows for a compressed representation of the microbial community. This approach uses a modified Bloom filter to store short k-mers with hash values that are unique to each bacterium. We show that most bacteria in many microbiomes can be represented uniquely using the proposed genomic signatures. This approach paves the way toward new methods for classifying bacteria in metagenomic samples.<\/jats:p>","DOI":"10.3389\/fdata.2022.1018356","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T05:21:11Z","timestamp":1668576071000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Representing bacteria with unique genomic signatures"],"prefix":"10.3389","volume":"5","author":[{"given":"Diem-Trang","family":"Pham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinhthuy","family":"Phan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,11,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1145\/362686.362692","article-title":"Space\/time trade-offs in hash coding with allowable errors","volume":"13","author":"Bloom","year":"1970","journal-title":"Commun. 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