{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T02:08:19Z","timestamp":1777342099592,"version":"3.51.4"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurorobot."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Precise identification of acupuncture points (acupoints) is essential for effective treatment, but manual location by untrained individuals can often lack accuracy and consistency. This study proposes two approaches that use artificial intelligence (AI) specifically computer vision to automatically and accurately identify acupoints on the face and hand in real-time, enhancing both precision and accessibility in acupuncture practices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The first approach applies a real-time landmark detection system to locate 38 specific acupoints on the face and hand by translating anatomical landmarks from image data into acupoint coordinates. The second approach uses a convolutional neural network (CNN) specifically optimized for pose estimation to detect five key acupoints on the arm and hand (LI11, LI10, TE5, TE3, LI4), drawing on constrained medical imaging data for training. To validate these methods, we compared the predicted acupoint locations with those annotated by experts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both approaches demonstrated high accuracy, with mean localization errors of less than 5 mm when compared to expert annotations. The landmark detection system successfully mapped multiple acupoints across the face and hand even in complex imaging scenarios. The data-driven approach accurately detected five arm and hand acupoints with a mean Average Precision (mAP) of 0.99 at OKS 50%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>These AI-driven methods establish a solid foundation for the automated localization of acupoints, enhancing both self-guided and professional acupuncture practices. By enabling precise, real-time localization of acupoints, these technologies could improve the accuracy of treatments, facilitate self-training, and increase the accessibility of acupuncture. Future developments could expand these models to include additional acupoints and incorporate them into intuitive applications for broader use.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnbot.2024.1484038","type":"journal-article","created":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T14:34:38Z","timestamp":1731940478000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":17,"title":["Real-time location of acupuncture points based on anatomical landmarks and pose estimation models"],"prefix":"10.3389","volume":"18","author":[{"given":"Hadi Sedigh","family":"Malekroodi","sequence":"first","affiliation":[]},{"given":"Seon-Deok","family":"Seo","sequence":"additional","affiliation":[]},{"given":"Jinseong","family":"Choi","sequence":"additional","affiliation":[]},{"given":"Chang-Soo","family":"Na","sequence":"additional","affiliation":[]},{"given":"Byeong-il","family":"Lee","sequence":"additional","affiliation":[]},{"given":"Myunggi","family":"Yi","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"ref1","first-page":"2597","article-title":"A combined deep learning and anatomical inch measurement approach to robotic acupuncture points positioning","author":"Chan","year":"2021"},{"key":"ref2","first-page":"239","article-title":"Localization of acupoints using augmented reality","author":"Chen","year":"2017"},{"key":"ref3","first-page":"932","article-title":"3D real-time face acupoints recognition system based on HoloLens 2","author":"Chen","year":"2021"},{"key":"ref4","volume-title":"Atlas of acupuncture","author":"Focks","year":"2008"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.jtcme.2022.10.005","article-title":"Role of acupuncture in critically ill patients: a systematic review","volume":"13","author":"Formenti","year":"2023","journal-title":"J. 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