{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T17:03:17Z","timestamp":1778259797245,"version":"3.51.4"},"reference-count":53,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Comput. Neurosci."],"abstract":"<jats:p>An optimal arrangement of electrodes during data collection is essential for gaining a deeper understanding of neonatal sleep and assessing cognitive health in order to reduce technical complexity and reduce skin irritation risks. Using electroencephalography (EEG) data, a long-short-term memory (LSTM) classifier categorizes neonatal sleep states. An 16,803 30-second segment was collected from 64 infants between 36 and 43 weeks of age at Fudan University Children's Hospital to train and test the proposed model. To enhance the performance of an LSTM-based classification model, 94 linear and nonlinear features in the time and frequency domains with three novel features (Detrended Fluctuation Analysis (DFA), Lyapunov exponent, and multiscale fluctuation entropy) are extracted. An imbalance between classes is solved using the SMOTE technique. In addition, the most significant features are identified and prioritized using principal component analysis (PCA). In comparison to other single channels, the C3 channel has an accuracy value of 80.75% \u00b1 0.82%, with a kappa value of 0.76. Classification accuracy for four left-side electrodes is higher (82.71% \u00b1 0.88%) than for four right-side electrodes (81.14% \u00b1 0.77%), while kappa values are respectively 0.78 and 0.76. Study results suggest that specific EEG channels play an important role in determining sleep stage classification, as well as suggesting optimal electrode configuration. Moreover, this research can be used to improve neonatal care by monitoring sleep, which can allow early detection of sleep disorders. As a result, this study captures information effectively using a single channel, reducing computing load and maintaining performance at the same time. With the incorporation of time and frequency-domain linear and nonlinear features into sleep staging, newborn sleep dynamics and irregularities can be better understood.<\/jats:p>","DOI":"10.3389\/fncom.2025.1506869","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T06:40:28Z","timestamp":1738305628000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["EEG electrode setup optimization using feature extraction techniques for neonatal sleep state classification"],"prefix":"10.3389","volume":"19","author":[{"given":"Hafza Ayesha","family":"Siddiqa","sequence":"first","affiliation":[]},{"given":"Muhammad Farrukh","family":"Qureshi","sequence":"additional","affiliation":[]},{"given":"Arsalan","family":"Khurshid","sequence":"additional","affiliation":[]},{"given":"Yan","family":"Xu","sequence":"additional","affiliation":[]},{"given":"Laishuan","family":"Wang","sequence":"additional","affiliation":[]},{"given":"Saadullah Farooq","family":"Abbasi","sequence":"additional","affiliation":[]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"183025","DOI":"10.1109\/ACCESS.2020.3028182","article-title":"EEG-based neonatal sleep-wake classification using multilayer perceptron neural network","volume":"8","author":"Abbasi","year":"2020","journal-title":"IEEE Access"},{"key":"B2","doi-asserted-by":"publisher","first-page":"4619","DOI":"10.32604\/cmc.2022.020318","article-title":"EEG-based neonatal sleep stage classification using ensemble learning","volume":"70","author":"Abbasi","year":"2022","journal-title":"Comput. 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