{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T01:52:06Z","timestamp":1780710726416,"version":"3.54.1"},"reference-count":49,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:00:00Z","timestamp":1755043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Artif. Intell."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Researchers in biomedicine and public health often spend weeks locating, cleansing, and integrating data from disparate sources before analysis can begin. This redundancy slows discovery and leads to inconsistent pipelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We created BioBricks.ai, an open, centralized repository that packages public biological and chemical datasets as modular \u201cbricks.\u201d Each brick is a Data Version Control (DVC) Git repository containing an extract\u2011transform\u2011load (ETL) pipeline. A package\u2011manager\u2013like interface handles installation, dependency resolution, and updates, while data are delivered through a unified backend (https:\/\/biobricks.ai).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The current release provides &amp;gt;90 curated datasets spanning genomics, proteomics, cheminformatics, and epidemiology. Bricks can be combined programmatically to build composite resources; benchmark use\u2011cases show that assembling multi\u2011dataset analytic cohorts is reduced from days to minutes compared with bespoke scripts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>BioBricks.ai accelerates data access, promotes reproducible workflows, and lowers the barrier for integrating heterogeneous public datasets. By treating data as version\u2011controlled software, the platform encourages community contributions and reduces redundant engineering effort. Continued expansion of brick coverage and automated provenance tracking will further enhance FAIR (Findable, Accessible, Interoperable, Reusable) data practices across the life\u2011science community.<\/jats:p><\/jats:sec>","DOI":"10.3389\/frai.2025.1599412","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T05:35:29Z","timestamp":1755063329000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["BioBricks.ai: a versioned data registry for life sciences data assets"],"prefix":"10.3389","volume":"8","author":[{"given":"Yifan","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakariyya","family":"Mughal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A.","family":"Jaramillo-Villegas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Corradi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Borrel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Lieberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suliman","family":"Sharif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Shaffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karamarie","family":"Fecho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Chatrath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Maertens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc A. 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