{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T05:18:18Z","timestamp":1775711898095,"version":"3.50.1"},"reference-count":64,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Robot. AI"],"abstract":"<jats:p>Inspired by some traits of human intelligence, it is proposed that <jats:italic>wetware<\/jats:italic> approaches based on molecular, supramolecular, and systems chemistry can provide valuable models and tools for novel forms of robotics and AI, being constituted by soft matter and fluid states as the human nervous system and, more generally, life, is. Bottom-up mimicries of intelligence range from the molecular world to the multicellular level, i.e., from the \u00c5ngstr\u00f6m (<jats:inline-formula><mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"m1\"><mml:mrow><mml:msup><mml:mn>10<\/mml:mn><mml:mrow><mml:mo>\u2212<\/mml:mo><mml:mn>10<\/mml:mn><\/mml:mrow><\/mml:msup><\/mml:mrow><\/mml:math><\/jats:inline-formula> meters) to the micrometer scales (<jats:inline-formula><mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"m2\"><mml:mrow><mml:msup><mml:mn>10<\/mml:mn><mml:mrow><mml:mo>\u2212<\/mml:mo><mml:mn>6<\/mml:mn><\/mml:mrow><\/mml:msup><\/mml:mrow><\/mml:math><\/jats:inline-formula> meters), and allows the development of unconventional chemical robotics. Whereas conventional robotics lets humans explore and colonise otherwise inaccessible environments, such as the deep oceanic abysses and other solar system planets, chemical robots will permit us to inspect and control the microscopic molecular and cellular worlds. This article suggests that systems made of properly chosen molecular compounds can implement all those modules that are the fundamental ingredients of every living being: sensory, processing, actuating, and metabolic networks. Autonomous chemical robotics will be within reach when such modules are compartmentalised and assembled. The design of a strongly intertwined web of chemical robots, with or without the involvement of living matter, will give rise to collective forms of intelligence that will probably reproduce, on a minimal scale, some sophisticated performances of the human intellect and will implement forms of \u201cgeneral AI.\u201d These remarkable achievements will require a productive interdisciplinary collaboration among chemists, biotechnologists, computer scientists, engineers, physicists, neuroscientists, cognitive scientists, and philosophers to be achieved. The principal purpose of this paper is to spark this revolutionary collaborative scientific endeavour.<\/jats:p>","DOI":"10.3389\/frobt.2023.1266011","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T08:43:04Z","timestamp":1697532184000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["Tracing a new path in the field of AI and robotics: mimicking human intelligence through chemistry. 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