{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:03:35Z","timestamp":1787731415254,"version":"build-2784847793"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Allergy"],"abstract":"<jats:p>The prevalence of allergic rhinitis (AR) is steadily rising in the Thai population, causing a major impact on the quality of life (QoL). Enhancing knowledge on common aeroallergens in the local setting helps in the appropriate prevention and management of AR. In this study, the demographic characteristics, clinical data, aeroallergen sensitization pattern, allergic symptoms, visual analog scale (VAS) score, and QoL are described. We evaluated the association between VAS, QoL, and severity of symptoms, except the aeroallergen sensitization pattern. We retrospectively reviewed the medical records of adult AR patients with a positive skin prick test (SPT) for at least one aeroallergen from January 2018 to May 2020. Standard descriptive and inferential statistics were used for analysis. A total of 366 patients were enrolled. Indoor aeroallergen sensitization and outdoor aeroallergen sensitization were observed in 32% and 7.9% of patients, respectively. Mono-sensitization was noted in 16.9% of patients, while poly-sensitization was noted in 83.1% of patients. Mites (65%) and sedge (39.3%) were the most common indoor and outdoor allergens. Nasal obstruction (74.6%), runny nose (63.7%), and nasal itchiness (61.5%) were the primary symptoms affecting the QoL. The association between VAS and symptom scores showed a trend of association with AR severity (Allergic Rhinitis and its Impact on Asthma [ARIA] classification) and VAS. AR has a significant effect on QoL in all domains of the validated generic (short-form-36, SF-36) and specific (rhino-conjunctivitis QoL questionnaire, Rcq-36) questionnaires. Mite and sedge remain the most common indoor and outdoor aeroallergens. The pattern of sensitization and number of aeroallergens were not associated with AR based on the ARIA guidelines. Meanwhile, symptoms of patients affected the QoL and VAS scores, which can be used as a quick and reliable tool for monitoring and stepping up or stepping down the treatment according to the next-generation guidelines. AR has a significant impact on the QoL of adult Thai patients.<\/jats:p>","DOI":"10.3389\/falgy.2021.695055","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T04:59:20Z","timestamp":1636952360000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Pattern of Aeroallergen Sensitization and Quality of Life in Adult Thai Patients With Allergic Rhinitis"],"prefix":"10.3389","volume":"2","author":[{"given":"Puspalal","family":"Katel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bannapuch","family":"Pinkaew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanokporn","family":"Talek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pongsakorn","family":"Tantilipikorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,11,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"S212","DOI":"10.1186\/1939-4551-5-S3-S212","article-title":"Allergic rhinitis and its impact on asthma in Asia pacific and the ARIA Update 2008","volume":"5","author":"Pawankar","year":"2012","journal-title":"World Allergy Organ J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e75","DOI":"10.1016\/j.ejim.2011.05.009","article-title":"IMonosensitization and polysensitization in allergic rhinitis","volume":"22","author":"Ciprandi","year":"2011","journal-title":"Eur J Intern Med."},{"key":"B3","first-page":"131","article-title":"The skin prick test results of 977 patients suffering from chronic rhinitis in Hong Kong","volume":"13","author":"Yuen","year":"2007","journal-title":"Hong Kong Med J."},{"key":"B4","doi-asserted-by":"publisher","first-page":"156","DOI":"10.12932\/AP-080719-0597","article-title":"Pattern of allergic sensitization in chronic rhinitis: A 19-year retrospective study","volume":"39","author":"Tantilipikorn","year":"2020","journal-title":"Asian Pac J Allergy Immunol."},{"key":"B5","first-page":"542","article-title":"Allergic rhinitis: evidence-based practice","volume":"51","author":"Lim","year":"2010","journal-title":"Singapore Med J."},{"key":"B6","first-page":"79","article-title":"Epidemiology and current status of allergic rhinitis and asthma in Thailand \u2013 ARIA Asia-Pacific Workshop report","volume":"27","author":"Bunnag","year":"2009","journal-title":"Asian Pac J Allergy Immunol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.5415\/apallergy.2018.8.e25","article-title":"Aeroallergen sensitization and associated comorbid diseases of an adult Filipino population with allergic rhinitis","volume":"8","author":"Navarro-Locsin","year":"2018","journal-title":"Asia Pac Allergy."},{"key":"B8","first-page":"99","article-title":"Quality of life assessment in Thai patients with allergic rhinoconjunctivitis using the SF-36 questionnaire (Thai version)","volume":"43","author":"Bunnag","year":"2005","journal-title":"Rhinology."},{"key":"B9","first-page":"69","article-title":"Development of a health-related quality of life questionnaire for Thai patients with rhinoconjunctivitis","volume":"22","author":"Bunnag","year":"2004","journal-title":"Asian Pac J Allergy Immunol."},{"key":"B10","first-page":"517","article-title":"Adverse reactions to allergen injection: the Siriraj experience","volume":"54","author":"Bunnag","year":"2002","journal-title":"Siriraj Med J"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e6","DOI":"10.5415\/apallergy.2019.9.e6","article-title":"Minimal clinically important difference for the rhinoconjunctivitis quality of life questionnaire in allergic rhinitis in Thai population","volume":"9","author":"Tantilipikorn","year":"2019","journal-title":"Asia Pac Allergy."},{"key":"B12","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s13223-015-0082-0","article-title":"The allergic rhinitis - clinical investigator collaborative (AR-CIC): nasal allergen challenge protocol optimization for studying AR pathophysiology and evaluating novel therapies","volume":"11","author":"Ellis","year":"2015","journal-title":"Allergy Asthma Clin Immunol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"e17","DOI":"10.5415\/apallergy.2018.8.e17","article-title":"Skin prick test reactivity to aeroallergens in adult allergy clinic in Thailand: a 12-year retrospective study","volume":"8","author":"Oncham","year":"2018","journal-title":"Asia Pac Allergy."},{"key":"B14","doi-asserted-by":"publisher","first-page":"181","DOI":"10.12932\/AP0770","article-title":"Aeroallergen sensitization and allergic disease phenotypes in Asia","volume":"34","author":"Tham","year":"2016","journal-title":"Asian Pac J Allergy Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1111\/j.1398-9995.2009.01967.x","article-title":"A multicentre study assessing the prevalence of sensitizations in patients with asthma and\/or rhinitis in China","volume":"64","author":"Li","year":"2009","journal-title":"Allergy."},{"key":"B16","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1111\/all.12364","article-title":"Allergic airway diseases in a tropical urban environment are driven by dominant mono-specific sensitization against house dust mites","volume":"69","author":"Andiappan","year":"2014","journal-title":"Allergy."},{"key":"B17","doi-asserted-by":"publisher","first-page":"182","DOI":"10.12932\/AP-261118-0447","article-title":"Patterns of sensitization to aeroallergens and their effect on airway hyper-responsiveness in Busan, Korea","volume":"39","author":"Jo","year":"2019","journal-title":"Asian Pac J Allergy Immunol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1111\/j.1365-2222.2004.02061.x","article-title":"Impacts of climate change on aeroallergens: past and future","volume":"34","author":"Beggs","year":"2004","journal-title":"Clin Exp Allergy."},{"key":"B19","doi-asserted-by":"publisher","first-page":"227","DOI":"10.3390\/atmos10050227","article-title":"Pollution characteristics and policy actions on fine particulate matter in a growing Asian economy: the case of Bangkok metropolitan region","volume":"10","author":"Narita","year":"2019","journal-title":"Atmosphere"},{"key":"B20","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s40733-015-0002-6","article-title":"The patient with rhinitis in the pharmacy. A cross-sectional study in real life","volume":"1","author":"Lombardi","year":"2015","journal-title":"Asthma Res Pract."},{"key":"B21","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5414\/ALX02120E","article-title":"ARIA guideline 2019: treatment of allergic rhinitis in the German health system","volume":"3","author":"Klimek","year":"2019","journal-title":"Allergol Select."},{"key":"B22","first-page":"237","article-title":"Allergic rhinitis and its impact on asthma update (ARIA 2008) \u2013 western and Asian-Pacific perspective","volume":"27","author":"Pawankar","year":"2009","journal-title":"Asian Pac J Allergy Immunol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1111\/j.1398-9995.2006.01276.x","article-title":"Visual analog scales can assess the severity of rhinitis graded according to ARIA guidelines","volume":"62","author":"Bousquet","year":"2007","journal-title":"Allergy."},{"key":"B24","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.jaci.2019.06.049","article-title":"Next-generation allergic rhinitis and its impact on asthma (ARIA) guidelines for allergic rhinitis based on grading of recommendations assessment, development and evaluation (GRADE) and real-world evidence","volume":"145","author":"Bousquet","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1186\/s13601-018-0227-6","article-title":"MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence","volume":"8","author":"Bousquet","year":"2018","journal-title":"Clin Transl Allergy."},{"key":"B26","doi-asserted-by":"crossref","first-page":"619","DOI":"10.47102\/annals-acadmedsg.V39N8p619","article-title":"Clinical features of allergic rhinitis and skin prick test analysis based on the ARIA classification: a preliminary study in Malaysia","volume":"39","author":"Asha'ari","year":"2010","journal-title":"Ann Acad Med Singap"}],"container-title":["Frontiers in Allergy"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/falgy.2021.695055\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,15]],"date-time":"2023-01-15T04:55:02Z","timestamp":1673758502000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/falgy.2021.695055\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,15]]},"references-count":26,"alternative-id":["10.3389\/falgy.2021.695055"],"URL":"https:\/\/doi.org\/10.3389\/falgy.2021.695055","relation":{},"ISSN":["2673-6101"],"issn-type":[{"value":"2673-6101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,15]]},"article-number":"695055"}}