{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T22:16:03Z","timestamp":1793744163074,"version":"4.6.1"},"reference-count":61,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T00:00:00Z","timestamp":1574121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"DOI":"10.3389\/fbioe.2019.00340","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T23:20:38Z","timestamp":1574119238000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":100,"title":["Small Caliber Compliant Vascular Grafts Based on Elastin-Like Recombinamers for in situ Tissue Engineering"],"prefix":"10.3389","volume":"7","author":[{"given":"Alicia","family":"Fern\u00e1ndez-Colino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"R\u00fctten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schmitz-Rode","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Carlos","family":"Rodr\u00edguez-Cabello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Jockenhoevel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Mela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,11,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/0741-5214(87)90148-0","article-title":"Effect of compliance mismatch on vascular graft patency","volume":"5","author":"Abbott","year":"1987","journal-title":"J. Vasc. Surg."},{"key":"B2","doi-asserted-by":"publisher","first-page":"819","DOI":"10.2174\/1568026614666140118223412","article-title":"Recent contributions of elastin-like recombinamers to biomedicine and nanotechnology","volume":"14","author":"Arias","year":"2014","journal-title":"Curr. Top. Med. Chem."},{"key":"B3","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/S0197-3975(97)00111-5","article-title":"Compliance mismatch may promote graft-artery intimal hyperplasia by altering suture-line stresses","volume":"31","author":"Ballyk","year":"1998","journal-title":"J. Biomech."},{"key":"B4","doi-asserted-by":"publisher","first-page":"6020","DOI":"10.1016\/j.biomaterials.2012.04.050","article-title":"A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering","volume":"33","author":"Billiet","year":"2012","journal-title":"Biomaterials"},{"key":"B5","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.actbio.2014.10.029","article-title":"Elastin-like recombinamer-covered stents: Towards a fully biocompatible and non-thrombogenic device for cardiovascular diseases","volume":"12","author":"de Torre","year":"2015","journal-title":"Acta Biomater."},{"key":"B6","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1002\/jbm.a.31926","article-title":"Fabrication of burst pressure competent vascular grafts via electrospinning: effects of microstructure","volume":"88","author":"Drilling","year":"2009","journal-title":"J. Biomed. Mater. Res. A"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.2337\/diacare.21.7.1178","article-title":"Stiffness indexes beta of the common carotid and femoral arteries are associated with insulin resistance in NIDDM","volume":"21","author":"Emoto","year":"1998","journal-title":"Diabetes Care"},{"key":"B8","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.msec.2018.03.013","article-title":"Macroporous click-elastin-like hydrogels for tissue engineering applications","volume":"88","author":"Fernandez-Colino","year":"2018","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"B9","doi-asserted-by":"publisher","first-page":"e0158555","DOI":"10.1371\/journal.pone.0158555","article-title":"Tissue-engineered small diameter arterial vascular grafts from cell-free nanofiber PCL\/chitosan scaffolds in a sheep model","volume":"11","author":"Fukunishi","year":"2016","journal-title":"PLoS ONE"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1002\/biot.201100116","article-title":"Elastin-like recombinamers: biosynthetic strategies and biotechnological applications","volume":"6","author":"Girotti","year":"2011","journal-title":"Biotechnol. J."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.1016\/j.actbio.2014.02.006","article-title":"Elastin-like recombinamer catalyst-free click gels: characterization of poroelastic and intrinsic viscoelastic properties","volume":"10","author":"Gonzalez de Torre","year":"2014","journal-title":"Acta Biomater."},{"key":"B12","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1002\/jbm.820230109","article-title":"Platelet shape change and cytoskeletal reorganization on polyurethaneureas","volume":"23","author":"Goodman","year":"1989","journal-title":"J. Biomed. Mater. Res."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1161\/CIRCULATIONAHA.113.008193","article-title":"Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV","volume":"130","author":"Hess","year":"2014","journal-title":"Circulation"},{"key":"B14","doi-asserted-by":"publisher","first-page":"M501","DOI":"10.1097\/00002480-199809000-00036","article-title":"Application of coacervated alpha-elastin to arterial prostheses for inhibition of anastomotic intimal hyperplasia","volume":"44","author":"Ito","year":"1998","journal-title":"ASAIO J."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1016\/j.biomaterials.2006.09.048","article-title":"The effect of a recombinant elastin-mimetic coating of an ePTFE prosthesis on acute thrombogenicity in a baboon arteriovenous shunt","volume":"28","author":"Jordan","year":"2007","journal-title":"Biomaterials"},{"key":"B16","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1002\/jbm.b.30247","article-title":"Current status of prosthetic bypass grafts: a review","volume":"74","author":"Kannan","year":"2005","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater."},{"key":"B17","doi-asserted-by":"publisher","first-page":"3487","DOI":"10.1016\/S0142-9612(02)00070-4","article-title":"PVDF as a new polymer for the construction of surgical meshes","volume":"23","author":"Klinge","year":"2002","journal-title":"Biomaterials"},{"key":"B18","doi-asserted-by":"publisher","first-page":"4731","DOI":"10.1016\/j.biomaterials.2010.02.051","article-title":"Fibrin-polylactide-based tissue-engineered vascular graft in the arterial circulation","volume":"31","author":"Koch","year":"2010","journal-title":"Biomaterials"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1016\/j.biomaterials.2008.11.011","article-title":"Mechanical properties of completely autologous human tissue engineered blood vessels compared to human saphenous vein and mammary artery","volume":"30","author":"Konig","year":"2009","journal-title":"Biomaterials"},{"key":"B20","doi-asserted-by":"publisher","first-page":"2705","DOI":"10.1073\/pnas.1017834108","article-title":"Substantial expression of mature elastin in arterial constructs","volume":"108","author":"Lee","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B21","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1038\/nm1364","article-title":"Human tissue engineered blood vessel for adult arterial revascularization","volume":"12","author":"L'Heureux","year":"2006","journal-title":"Nat. Med."},{"key":"B22","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1002\/bip.21327","article-title":"Elastin-like polypeptides: biomedical applications of tunable biopolymers","volume":"94","author":"MacEwan","year":"2010","journal-title":"Biopolymers"},{"key":"B23","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1093\/qjmed\/95.2.67","article-title":"Assessment of arterial stiffness in clinical practice","volume":"95","author":"Mackenzie","year":"2002","journal-title":"QJM"},{"key":"B24","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1002\/path.2840","article-title":"Fibrillin-1 genetic deficiency leads to pathological aging of arteries in mice","volume":"224","author":"Mariko","year":"2011","journal-title":"J. Pathol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"3015","DOI":"10.1021\/bm900560a","article-title":"Synthesis and characterization of macroporous thermosensitive hydrogels from recombinant elastin-like polymers","volume":"10","author":"Martin","year":"2009","journal-title":"Biomacromolecules"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1016\/S0140-6736(09)60248-8","article-title":"Effectiveness of haemodialysis access with an autologous tissue-engineered vascular graft: a multicentre cohort study","volume":"373","author":"McAllister","year":"2009","journal-title":"Lancet"},{"key":"B27","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1089\/ten.tec.2015.0562","article-title":"In vitro endothelialization of biodegradable vascular grafts via endothelial progenitor cell seeding and maturation in a tubular perfusion system bioreactor","volume":"22","author":"Melchiorri","year":"2016","journal-title":"Tissue Eng. Part C Methods"},{"key":"B28","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.biomaterials.2014.10.076","article-title":"USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts","volume":"39","author":"Mertens","year":"2015","journal-title":"Biomaterials"},{"key":"B29","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1089\/ten.tec.2014.0214","article-title":"Tissue-engineered heart valve with a tubular leaflet design for minimally invasive transcatheter implantation","volume":"21","author":"Moreira","year":"2015","journal-title":"Tissue Eng. Part C"},{"key":"B30","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/S1350-4533(98)00050-2","article-title":"Changes in the mechanical properties, biochemical contents and wall structure of the human coronary arteries with age and sex","volume":"20","author":"Ozolanta","year":"1998","journal-title":"Med. Eng. Phys."},{"key":"B31","doi-asserted-by":"publisher","first-page":"108079","DOI":"10.1016\/j.matdes.2019.108079","article-title":"Fabrication of strong, bioactive vascular grafts with PCL\/collagen and PCL\/silica bilayers for small-diameter vascular applications","volume":"181","author":"Park","year":"2019","journal-title":"Mater. Des."},{"key":"B32","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1089\/ten.teb.2015.0100","article-title":"The tissue-engineered vascular graft-past, present, and future","volume":"22","author":"Pashneh-Tala","year":"2015","journal-title":"Tissue Eng. Part B Rev"},{"key":"B33","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.cardiores.2006.02.021","article-title":"Elastin biosynthesis: the missing link in tissue-engineered blood vessels","volume":"71","author":"Patel","year":"2006","journal-title":"Cardiovasc. Res."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.7150\/ijbs.7502","article-title":"The vascular endothelium and human diseases","volume":"9","author":"Rajendran","year":"2013","journal-title":"Int. J. Biol. Sci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1096\/fasebj.7.13.8405806","article-title":"Extracellular matrix 4: the elastic fiber","volume":"7","author":"Rosenbloom","year":"1993","journal-title":"FASEB J."},{"key":"B36","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1106\/NA5T-J57A-JTDD-FD04","article-title":"The mechanical behavior of vascular grafts: a review","volume":"15","author":"Salacinski","year":"2001","journal-title":"J. Biomater. Appl."},{"key":"B37","doi-asserted-by":"publisher","first-page":"302","DOI":"10.2174\/1874192401004010302","article-title":"The endothelium and its role in regulating vascular tone","volume":"4","author":"Sandoo","year":"2010","journal-title":"Open Cardiovasc. Med. J."},{"key":"B38","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/j.ejvs.2006.01.006","article-title":"The mechanical properties of infrainguinal vascular bypass grafts: their role in influencing patency","volume":"31","author":"Sarkar","year":"2006","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"B39","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s11517-007-0176-z","article-title":"Achieving the ideal properties for vascular bypass grafts using a tissue engineered approach: a review","volume":"45","author":"Sarkar","year":"2007","journal-title":"Med. Biol. Eng. Comput."},{"key":"B40","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.actbio.2009.06.026","article-title":"A bilayered elastomeric scaffold for tissue engineering of small diameter vascular grafts","volume":"6","author":"Soletti","year":"2010","journal-title":"Acta Biomater."},{"key":"B41","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1080\/19336918.2016.1173803","article-title":"Toward correlating structure and mechanics of platelets","volume":"10","author":"Sorrentino","year":"2016","journal-title":"Cell Adh. Migr."},{"key":"B42","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1007\/s12265-016-9699-8","article-title":"Old myths, new concerns: the long-term effects of ascending aorta replacement with dacron grafts. Not all that glitters is gold","volume":"9","author":"Spadaccio","year":"2016","journal-title":"J. Cardiovasc. Transl. Res."},{"key":"B43","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/j.athoracsur.2016.01.110","article-title":"Novel bioresorbable vascular graft with sponge-type scaffold as a small-diameter arterial graft","volume":"102","author":"Sugiura","year":"2016","journal-title":"Ann. Thorac. Surg."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1046\/j.1365-2168.2000.01566.x","article-title":"Compliance properties of conduits used in vascular reconstruction","volume":"87","author":"Tai","year":"2000","journal-title":"Br. J. Surg."},{"key":"B45","doi-asserted-by":"publisher","first-page":"2583","DOI":"10.1089\/ten.tea.2015.0066","article-title":"In situ tissue engineering of functional small-diameter blood vessels by host circulating cells only","volume":"21","author":"Talacua","year":"2015","journal-title":"Tissue Eng. Part A"},{"key":"B46","doi-asserted-by":"publisher","first-page":"3232","DOI":"10.1093\/eurheartj\/ehw334","article-title":"Cardiovascular disease in Europe: epidemiological update 2016","volume":"37","author":"Townsend","year":"2016","journal-title":"Eur. Heart J."},{"key":"B47","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/S1078-5884(05)80163-7","article-title":"Compliance mismatch and formation of distal anastomotic intimal hyperplasia in externally stiffened and lumen-adapted venous grafts","volume":"10","author":"Trubel","year":"1995","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"B48","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1097\/00002480-198907000-00124","article-title":"Compliance effect on patency of small diameter vascular grafts","volume":"35","author":"Uchida","year":"1989","journal-title":"ASAIO Trans."},{"key":"B49","doi-asserted-by":"publisher","first-page":"2130","DOI":"10.1161\/CIRCULATIONAHA.118.035231","article-title":"Rapid self-assembly of bioengineered cardiovascular bypass grafts from scaffold-stabilized, tubular bilevel cell sheets","volume":"138","author":"von Bornstadt","year":"2018","journal-title":"Circulation"},{"key":"B50","doi-asserted-by":"publisher","first-page":"2345","DOI":"10.1242\/dev.093500","article-title":"Elastogenesis at the onset of human cardiac valve development","volume":"140","author":"Votteler","year":"2013","journal-title":"Development"},{"key":"B51","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1038\/s41536-017-0023-2","article-title":"Biomaterial-driven in situ cardiovascular tissue engineering\u2014a multi-disciplinary perspective","volume":"2","author":"Wissing","year":"2017","journal-title":"NPJ Regenerat. Med."},{"key":"B52","doi-asserted-by":"publisher","first-page":"119228","DOI":"10.1016\/j.biomaterials.2019.119228","article-title":"MR and PET-CT monitoring of tissue-engineered vascular grafts in the ovine carotid artery","volume":"216","author":"Wolf","year":"2019","journal-title":"Biomaterials"},{"key":"B53","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1007\/s10439-018-1977-y","article-title":"VascuTrainer: a mobile and disposable bioreactor system for the conditioning of tissue-engineered vascular grafts","volume":"46","author":"Wolf","year":"2018","journal-title":"Ann. Biomed. Eng."},{"key":"B54","doi-asserted-by":"publisher","first-page":"4543","DOI":"10.1016\/j.biomaterials.2003.11.043","article-title":"Investigation of recombinant human elastin polypeptides as non-thrombogenic coatings","volume":"25","author":"Woodhouse","year":"2004","journal-title":"Biomaterials"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1038\/nm.2821","article-title":"Fast degrading elastomer enables rapid remodeling of a cell-free synthetic graft into a neo-artery","volume":"18","author":"Wu","year":"2012","journal-title":"Nat. Med."},{"key":"B56","doi-asserted-by":"publisher","first-page":"e0131101","DOI":"10.1371\/journal.pone.0131101","article-title":"Characterization of endothelial progenitor cell interactions with human tropoelastin","volume":"10","author":"Yu","year":"2015","journal-title":"PLoS ONE"},{"key":"B57","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1002\/jbm.a.30614","article-title":"A sandwich tubular scaffold derived from chitosan for blood vessel tissue engineering","volume":"77","author":"Zhang","year":"2006","journal-title":"J. Biomed. Mater. Res. A"},{"key":"B58","doi-asserted-by":"publisher","first-page":"025010","DOI":"10.1088\/1758-5090\/aa730a","article-title":"A compliant and biomimetic three-layered vascular graft for small blood vessels","volume":"9","author":"Zhang","year":"2017","journal-title":"Biofabrication"},{"key":"B59","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.actbio.2019.07.057","article-title":"Co-immobilization of ACH11 antithrombotic peptide and CAG cell-adhesive peptide onto vascular grafts for improved hemocompatibility and endothelialization","volume":"97","author":"Zhao","year":"2019","journal-title":"Acta Biomater"},{"key":"B60","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1089\/ten.teb.2011.0390","article-title":"Fabrication of large pores in electrospun nanofibrous scaffolds for cellular infiltration: a review","volume":"18","author":"Zhong","year":"2012","journal-title":"Tissue Eng. Part B Rev."},{"key":"B61","doi-asserted-by":"publisher","first-page":"5009","DOI":"10.1016\/j.biomaterials.2007.07.017","article-title":"Prosthetic vascular grafts: wrong models, wrong questions and no healing","volume":"28","author":"Zilla","year":"2007","journal-title":"Biomaterials"}],"container-title":["Frontiers in Bioengineering and Biotechnology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fbioe.2019.00340\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T23:20:41Z","timestamp":1574119241000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fbioe.2019.00340\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,19]]},"references-count":61,"alternative-id":["10.3389\/fbioe.2019.00340"],"URL":"https:\/\/doi.org\/10.3389\/fbioe.2019.00340","relation":{},"ISSN":["2296-4185"],"issn-type":[{"value":"2296-4185","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,19]]},"article-number":"340"}}