{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:05:07Z","timestamp":1782842707810,"version":"3.54.5"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21978071 and U1932141"],"award-info":[{"award-number":["21978071 and U1932141"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"DOI":"10.3389\/fbioe.2020.00957","type":"journal-article","created":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T06:21:20Z","timestamp":1598854880000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":24,"title":["The Magnesium Concentration in Yeast Extracts Is a Major Determinant Affecting Ethanol Fermentation Performance of Zymomonas mobilis"],"prefix":"10.3389","volume":"8","author":[{"given":"Runxia","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingjie","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouwen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,8,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.03034-16","article-title":"Increasing growth yield and decreasing acetylation in Escherichia coli by optimizing the carbon-to-magnesium ratio in peptide-based media.","volume":"83","author":"Christensen","year":"2017","journal-title":"Appl. Environ. Microbiol."},{"key":"B2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.1992.tb05822.x","article-title":"The entner-doudoroff pathway. history, physiology and molecular biology.","volume":"9","author":"Conway","year":"1992","journal-title":"FEMS Microbiol. Rev."},{"key":"B3","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/j.1567-1364.2006.00152.x","article-title":"Physiological behaviour of Saccharomyces cerevisiae in aerated fed-batch fermentation for high level production of bioethanol.","volume":"7","author":"Cot","year":"2007","journal-title":"FEMS Yeast Res."},{"key":"B4","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1007\/s00253-003-1444-y","article-title":"Bacteria engineered for fuel ethanol production. current status.","volume":"63","author":"Dien","year":"2003","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"B5","doi-asserted-by":"crossref","DOI":"10.1186\/s13068-019-1463-2","article-title":"Replacing water and nutrients for ethanol production by ARTP derived biogas slurry tolerant Zymomonas mobilis strain.","volume":"12","author":"Duan","year":"2019","journal-title":"Biotechnol. Biofuels"},{"key":"B6","doi-asserted-by":"publisher","first-page":"10039","DOI":"10.1073\/pnas.1215283110","article-title":"Glycolytic strategy as a tradeoff between energy yield and protein cost.","volume":"110","author":"Flamholz","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B7","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.jbiotec.2009.08.006","article-title":"Development of a high-throughput method to evaluate the impact of inhibitory compounds from lignocellulosic hydrolysates on the growth of Zymomonas mobilis.","volume":"144","author":"Franden","year":"2009","journal-title":"J. Biotechnol."},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1186\/1754-6834-7-101","article-title":"Zymomonas mobilis. a novel platform for future biorefineries.","volume":"7","author":"He","year":"2014","journal-title":"Biotechnol. Biofuels"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1186\/1754-6834-5-75","article-title":"Transcriptome profiling of Zymomonas mobilis under ethanol stress.","volume":"5","author":"He","year":"2012","journal-title":"Biotechnol. Biofuels"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1002\/biot.201300553","article-title":"Zinc, magnesium, and calcium ion supplementation confers tolerance to acetic acid stress in industrial Saccharomyces cerevisiae utilizing xylose.","volume":"9","author":"Ismail","year":"2014","journal-title":"Biotechnol. J."},{"key":"B11","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.ymben.2019.05.006","article-title":"2H and 13C metabolic flux analysis elucidates in vivo thermodynamics of the ED pathway in Zymomonas mobilis.","volume":"54","author":"Jacobson","year":"2019","journal-title":"Metab. Eng."},{"key":"B12","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/BF00180626","article-title":"Kinetic control of ethanol production by Zymomonas mobilis.","volume":"35","author":"Jones","year":"1991","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1007\/bf01386658","article-title":"Continuous ethanol fermentation of Zymomonas mobilis using soy flour as a protective agent.","volume":"5","author":"Ju","year":"1983","journal-title":"Biotechnol. Lett."},{"key":"B14","doi-asserted-by":"publisher","first-page":"10191","DOI":"10.1007\/s00253-015-6835-3","article-title":"Influence of nitrogen sources on growth and fermentation performance of different wine yeast species during alcoholic fermentation.","volume":"99","author":"Kemsawasd","year":"2015","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1016\/s0969-2126(96)00149-9","article-title":"The structure of glucose-fructose oxidoreductase from Zymomonas mobilis. an osmoprotective periplasmic enzyme containing non-dissociable NADP.","volume":"4","author":"Kingston","year":"1996","journal-title":"Structure"},{"key":"B16","doi-asserted-by":"publisher","first-page":"4633","DOI":"10.1039\/c7gc01796k","article-title":"Nutritional requirements and the impact of yeast extract on the d-lactic acid production by Sporolactobacillus inulinus.","volume":"19","author":"Klotz","year":"2017","journal-title":"Green Chem."},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00502","article-title":"Enhancement of thermal resistance by metal ions in thermotolerant Zymomonas mobilis TISTR 548.","volume":"11","author":"Kosaka","year":"2020","journal-title":"Front. Microbiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"2222","DOI":"10.1073\/pnas.1420663112","article-title":"N2 gas is an effective fertilizer for bioethanol production by Zymomonas mobilis.","volume":"112","author":"Kremer","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B19","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/978-1-4612-2312-2_25","article-title":"Corn steep liquor as a cost-effective nutrition adjunct in high-performance Zymomonas ethanol fermentations.","volume":"6","author":"Lawford","year":"1997","journal-title":"Appl. Biochem. Biotechnol."},{"key":"B21","doi-asserted-by":"crossref","DOI":"10.1186\/s12934-019-1202-1","article-title":"Engineering protein production by rationally choosing a carbon and nitrogen source using E. coli BL21 acetate metabolism knockout strains.","volume":"18","author":"Lozano Terol","year":"2019","journal-title":"Microbial. Cell Factories"},{"key":"B22","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1111\/j.1567-1364.2012.00802.x","article-title":"Biomass production and alcoholic fermentation performance of Saccharomyces cerevisiae as a function of nitrogen source.","volume":"12","author":"Martinez-Moreno","year":"2012","journal-title":"FEMS Yeast Res."},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2859-12-29","article-title":"The metabolic costs of improving ethanol yield by reducing glycerol formation capacity under anaerobic conditions in Saccharomyces cerevisiae.","volume":"12","author":"Pagliardini","year":"2013","journal-title":"Microb. Cell Fact."},{"key":"B24","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1002\/jctb.1448","article-title":"Zymomonas mobilis. an alternative ethanol producer.","volume":"81","author":"Panesar","year":"2006","journal-title":"J. Chem. Technol. Biotechnol."},{"key":"B25","first-page":"133","article-title":"Zymomonas ethanol fermentations.","volume":"1","author":"Rogers","year":"1984","journal-title":"Microbiol. Sci."},{"key":"B26","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/10_2007_060","article-title":"Zymomonas mobilis for fuel ethanol and higher value products.","volume":"108","author":"Rogers","year":"2007","journal-title":"Adv. Biochem. Eng. Biotechnol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.ymben.2018.04.001","article-title":"Advances and prospects in metabolic engineering of Zymomonas mobilis.","volume":"50","author":"Wang","year":"2018","journal-title":"Metab. Eng."},{"key":"B28","doi-asserted-by":"publisher","first-page":"2714","DOI":"10.1002\/bit.26806","article-title":"Contribution of cellulose synthesis, formation of fibrils and their entanglement to the self-flocculation of Zymomonas mobilis.","volume":"115","author":"Xia","year":"2018","journal-title":"Biotechnol. Bioeng."},{"key":"B29","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1002\/bit.22610","article-title":"Effect of the size of yeast flocs and zinc supplementation on continuous ethanol fermentation performance and metabolic flux distribution under very high concentration conditions.","volume":"105","author":"Xue","year":"2010","journal-title":"Biotechnol. Bioeng."},{"key":"B30","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1111\/1751-7915.12408","article-title":"Zymomonas mobilis as a model system for production of biofuels and biochemicals.","volume":"9","author":"Yang","year":"","journal-title":"Microb. Biotechnol."},{"key":"B31","article-title":"Metabolic engineering of Zymomonas mobilis for 2,3-butanediol production from lignocellulosic biomass sugars.","volume":"9","author":"Yang","year":"","journal-title":"Biotechnol. Biofuels"},{"key":"B32","article-title":"Insights into acetate toxicity in Zymomonas mobilis 8b using different substrates.","volume":"7","author":"Yang","year":"","journal-title":"Biotechnol. Biofuels"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00246","article-title":"Elucidation of Zymomonas mobilis physiology and stress responses by quantitative proteomics and transcriptomics.","volume":"5","author":"Yang","year":"","journal-title":"Front. Microbiol."},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2018.00023","article-title":"Identification of inhibitors in lignocellulosic slurries and determination of their effect on hydrocarbon-producing microorganisms.","volume":"6","author":"Yang","year":"2018","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"10395","DOI":"10.1073\/pnas.0914506107","article-title":"Paradigm for industrial strain improvement identifies sodium acetate tolerance loci in Zymomonas mobilis and Saccharomyces cerevisiae.","volume":"107","author":"Yang","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B36","doi-asserted-by":"crossref","DOI":"10.1186\/s40643-018-0193-9","article-title":"Progress and perspective on lignocellulosic hydrolysate inhibitor tolerance improvement in Zymomonas mobilis.","volume":"5","author":"Yang","year":"2018","journal-title":"Bioresour. Bioprocess."},{"key":"B37","first-page":"907","article-title":"A simple and rapid protocol for producing yeast extract from Saccharomyces cerevisiae suitable for preparing bacterial culture media.","volume":"15","author":"Zarei","year":"2016","journal-title":"Iran J. Pharm. Res."},{"key":"B38","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.jbiotec.2011.06.038","article-title":"Zinc and yeast stress tolerance. micronutrient plays a big role.","volume":"158","author":"Zhao","year":"2012","journal-title":"J. Biotechnol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.jbiotec.2008.08.013","article-title":"Impact of zinc supplementation on the improvement of ethanol tolerance and yield of self-flocculating yeast in continuous ethanol fermentation.","volume":"139","author":"Zhao","year":"2009","journal-title":"J. Biotechnol."}],"container-title":["Frontiers in Bioengineering and Biotechnology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fbioe.2020.00957\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T21:20:16Z","timestamp":1723497616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fbioe.2020.00957\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,31]]},"references-count":38,"alternative-id":["10.3389\/fbioe.2020.00957"],"URL":"https:\/\/doi.org\/10.3389\/fbioe.2020.00957","relation":{},"ISSN":["2296-4185"],"issn-type":[{"value":"2296-4185","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,31]]},"article-number":"957"}}