{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:27:20Z","timestamp":1793132840488,"version":"4.5.0"},"reference-count":53,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T00:00:00Z","timestamp":1695600000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:p>The human brain is an extremely intricate and fascinating organ that is made up of the cerebrum, cerebellum, and brainstem and is protected by the skull. Brain stroke is recognized as a potentially fatal condition brought on by an unfavorable obstruction in the arteries supplying the brain. The severity of brain stroke may be reduced or controlled with its early prognosis to lessen the mortality rate and lead to good health. This paper proposed a technique to predict brain strokes with high accuracy. The model was constructed using data related to brain strokes. The aim of this work is to use Multi Layer Perceptron (MLP) as a classification technique for stroke data and used multi-optimizers that include Adaptive moment estimation with Maximum (AdaMax), Root Mean Squared Propagation (RMSProp) and Adaptive learning rate method (Adadelta). The experiment shows RMSProp optimizer is best with a data training accuracy of 95.8% and a value for data testing accuracy of 94.9%. The novelty of work is to incorporate multiple optimizers alongside the MLP classifier which offers a comprehensive approach to stroke prediction, providing a more robust and accurate solution. The obtained results underscore the effectiveness of the proposed methodology in enhancing the accuracy of brain stroke detection, thereby paving the way for potential advancements in medical diagnosis and treatment.<\/jats:p>","DOI":"10.3389\/fbioe.2023.1257591","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T06:39:56Z","timestamp":1695710396000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":49,"title":["Enhancing accuracy in brain stroke detection: Multi-layer perceptron with Adadelta, RMSProp and AdaMax optimizers"],"prefix":"10.3389","volume":"11","author":[{"given":"Mudita","family":"Uppal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepali","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapna","family":"Juneja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thippa Reddy","family":"Gadekallu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"El Bayoumy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamil","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Won","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,9,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.3390\/su15021695","article-title":"An artificial intelligence-based stacked ensemble approach for prediction of protein subcellular localization in confocal microscopy images","volume":"15","author":"Aggarwal","year":"2023","journal-title":"Sustainability"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.14569\/ijacsa.2018.090163","article-title":"Prediction of stroke using data mining classification techniques","volume":"9","author":"Almadani","year":"2018","journal-title":"Int. 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