{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:57:02Z","timestamp":1793408222517,"version":"4.5.0"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T00:00:00Z","timestamp":1708646400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"publisher","award":["2022\/CP\/048"],"award-info":[{"award-number":["2022\/CP\/048"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:p><jats:bold>Introduction:<\/jats:bold> Poor patellar tracking can result in painful contact pressures, patella subluxation, or dislocation. The use of musculoskeletal models and simulations in orthopedic surgeries allows for objective predictions of post-treatment function, empowering clinicians to explore diverse treatment options for patients. Although a promising approach for managing knee surgeries, the high computational cost of the Finite Element Method hampers its clinical usability. In anticipation of minimal elastic deformations in the involved bodies, the exploration of the Multibody Dynamics approach emerged as a viable solution, providing a computationally efficient methodology to address clinical concerns related to the knee joint.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> This work, with a focus on high-performance computing, achieved the simulation of the patellofemoral joint through rigid-body multibody dynamics formulations. A comparison was made between two collision detection algorithms employed in the simulation of contact between the patellar and femoral implants: a generic mesh-to-mesh collision detection algorithm, which identifies potential collisions between bodies by checking for proximity or overlap between their discretized mesh surface elements, and an analytical contact algorithm, which uses a mathematical model to provide closed-form solutions for specific contact problems, but cannot handle arbitrary geometries. In addition, different digital twins (3D model geometries) of the femoral implant were compared.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Computational efficiency was considered, and histories of position, orientation, and contact force of the patella during the motion were compared with experimental measurements obtained from a sensorized 3D-printed test bench under pathological and treatment scenarios. The best results were achieved through a purely analytical contact detection algorithm, allowing for clinical usability and optimization of clinical outcomes.<\/jats:p>","DOI":"10.3389\/fbioe.2024.1347720","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T04:47:20Z","timestamp":1708663640000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["Use of patellofemoral digital twins for patellar tracking and treatment prediction: comparison of 3D models and contact detection algorithms"],"prefix":"10.3389","volume":"12","author":[{"given":"Florian","family":"Michaud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Luaces","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Mouzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Cuadrado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,2,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1007\/s00167-014-3421-7","article-title":"The effects of the sagittal plane malpositioning of the patella and concomitant quadriceps hypotrophy on the patellofemoral joint: a finite element analysis","volume":"24","author":"Aksahin","year":"2016","journal-title":"Knee Surg. 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