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Biotechnol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Lower limb exoskeleton robots for young children with cerebral palsy (CP) are crucial to support earlier rehabilitation that is more beneficial than later. For safety reasons, pediatric exoskeletons are usually equipped with body weight support (BWS) devices to help young patients maintain balance. However, existing pediatric exoskeletons tend to use stiff joint actuation and passive BWS with limited compliance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This paper proposes a novel mobile exoskeleton robot for young children (3- \u223c 6-years-old) with CP based on intrinsically compliant actuation. A compact kinematic chain that integrates an exoskeleton, an active BWS system, and a walker is proposed. Furthermore, with the actuation design optimization of the kinematic chain, the robot can walk alone stably in passive rehabilitation and provide high compliance in active rehabilitation. The exoskeleton adopts actuation similar to the quasi-direct drive paradigm to acquire high mechanical compliance and uses a secondary planetary reducer to ensure high output torque. Assistive torque control is achieved through proprioceptive sensing instead of torque sensors. The BWS system uses a series elastic actuator to accurately generate the weight support force and significantly reduce the fluctuation of the support force compared to the passive BWS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results and discussion<\/jats:title><jats:p>Finally, control frameworks for passive and active rehabilitation are implemented to validate the robot performance. The experimental results demonstrate that our robot can support safe and compliant rehabilitation.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fbioe.2025.1551039","type":"journal-article","created":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T07:18:57Z","timestamp":1740640737000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["ChMER: an exoskeleton robot with active body weight support walker based on compliant actuation for children with cerebral palsy"],"prefix":"10.3389","volume":"13","author":[{"given":"Yuantao","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengtao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peizhong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suiran","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/S1474-4422(11)70176-4","article-title":"Cerebral palsy: clinical care and neurological rehabilitation","volume":"10","author":"Aisen","year":"2011","journal-title":"Lancet Neurol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1111\/dmcn.13385","article-title":"Stability of the Gross Motor Function Classification System in children and adolescents with cerebral palsy: a retrospective cohort registry study","volume":"59","author":"Alriksson-Schmidt","year":"2017","journal-title":"Dev. 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