{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:56:51Z","timestamp":1784044611538,"version":"3.55.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Computer-assisted navigation has been established as a valuable tool in oral and craniomaxillofacial surgery. However, the steep learning curve associated with mandibular navigation surgery has hindered its widespread adoption. This study introduces a non-invasive, convenient, and accurate navigation method for mandibular surgery and evaluates its clinical effectiveness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A modified patient-specific dynamic reference frame (PS-DRF) was designed and fabricated based on the patient\u2019s lower jaw dental cast, integrating navigation technology with 3D printing. During surgery, the PS-DRF was securely affixed to the lower dentition, enabling automatic pair-point registration through fiducial localization via a navigation probe. The surgical procedure was conducted under real-time navigation guidance. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Preoperative registration and intraoperative navigation were successfully achieved in this case. The navigation-guided mandibular surgery was completed without complications. Postoperative superimposition of the simulated virtual model and the actual surgical outcome demonstrated high accuracy, with a deviation of less than 2 mm. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The PS-DRF system offers a convenient, effective, and adaptable approach by integrating navigation technology with 3D printing. This method has the potential to simplify navigation-assisted mandibular surgery and facilitate the broader clinical implementation of computer-assisted navigation in maxillofacial procedures.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fbioe.2025.1577321","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T06:14:12Z","timestamp":1747116852000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Patient-specific dynamic reference frame for navigation-assisted surgery in mandible: a novel noninvasive technical method"],"prefix":"10.3389","volume":"13","author":[{"given":"Jinyang","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lai","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingqi","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1097\/scs.0000000000003816","article-title":"Mandibular surgical navigation: an innovative guiding method","volume":"28","author":"Abbate","year":"2017","journal-title":"J. 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