{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T05:46:12Z","timestamp":1782193572823,"version":"3.54.5"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T00:00:00Z","timestamp":1756080000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Due to its inherent high instability, the selection of fixation strategies for unilateral Denis type II sacral fractures remains a controversial challenge in the field of traumatic orthopedics. This study focuses on unilateral Denis type II sacral fractures. By applying three different fixation methods, it aims to explore their biomechanical properties and provide a theoretical basis for optimizing clinical fixation protocols.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A ligament-intact three-dimensional finite-element model of a right-sided Denis type II sacral fracture, including ipsilateral superior and inferior pubic rami fractures, was generated. Three fixation models were simulated: (1) S1\/S2 transiliac-transsacral screw fixation (S1\/S2-TTS); (2) unilateral L4\/5 triangular osteosynthesis (UTOS); and (3) bilateral S2-alar-iliac screws combined with an iliosacral screw (BS2AI-ISS). Appropriate material properties, boundary conditions, and loading protocols were assigned. A 500\u00a0N axial compressive load superimposed with a 7.5\u00a0Nm torque was applied to simulate standing position and multiplanar spinal motion. Biomechanical parameters evaluated included vertical sacral stiffness, maximum von Mises stress within implants, and relative interfragmentary displacement (RID) at the fracture site.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sacrum vertical stiffness: All constructs significantly increased sacrum vertical stiffness compared with the intact model. Normalised stiffness values were 443.18% (S1\/S2-TTS), 228.38% (UTOS) and 397.26% (BS2AI-ISS). Maximum implant von Mises stress: Under every loading mode, S1\/S2-TTS exhibited the lowest and most evenly distributed stress (range 30.30\u201349.23\u00a0MPa). Maximum stresses ranked from lowest to highest: S1\/S2-TTS &amp;lt; BS2AI-ISS &amp;lt; UTOS. Relative interfragmentary displacement: In standing position, mean RID were 0.0313 \u00b1 0.0148\u00a0mm (S1\/S2-TTS), 0.0736 \u00b1 0.0314\u00a0mm (UTOS) and 0.0539 \u00b1 0.0163\u00a0mm (BS2AI-ISS). Only the difference between S1\/S2-TTS and UTOS reached statistical significance (p = 0.047). Similar patterns were observed in extension, left flexion and left rotation; no significant differences were found in right flexion or right rotation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study demonstrates that BS2AI-ISS provides biomechanical stability comparable to both S1\/S2-TTS and UTOS for unilateral Denis type II sacral fractures. Notably, BS2AI-ISS achieves this stability without compromising lumbar motion and irrespective of sacral morphologic variations. These findings suggest that BS2AI-ISS may serve as an effective alternative for managing unilateral Denis type II sacral fractures.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fbioe.2025.1631457","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T07:50:36Z","timestamp":1756108236000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["A biomechanical investigation of three fixation methods for unilateral denis type II sacral fractures using finite element analysis"],"prefix":"10.3389","volume":"13","author":[{"given":"Peishuai","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renjie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongsheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1002\/jor.23798","article-title":"Biomechanical investigation of four different fixation techniques in sacrum denis type II fracture with low bone mineral density","volume":"36","author":"Acklin","year":"2018","journal-title":"J. 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