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As a critical component of the human immune system, neutrophils play a pivotal role in modulating the inflammatory response, influencing the processes of osteogenesis and osteoclastogenesis, and impacting fracture healing. In the field of bone tissue engineering, the optimization of the chemical composition and morphology of scaffold materials can effectively modulate neutrophil behavior, thereby enhancing the antibacterial properties and osteogenic potential of the scaffolds. 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