{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T06:34:41Z","timestamp":1763966081149,"version":"3.45.0"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016692","name":"Key Research and Development Program of Ningxia","doi-asserted-by":"publisher","award":["2023BEG02017"],"award-info":[{"award-number":["2023BEG02017"]}],"id":[{"id":"10.13039\/100016692","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The surgical management of severe, rigid adult idiopathic scoliosis (AdIS) is challenging. While posterior intervertebral release (PIVR) is used to enhance correction, the optimal number of release segments is unknown. This study aimed to identify the optimal PIVR strategy by evaluating the biomechanical effects of varying release levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A patient-specific finite element (FE) model of a Lenke 2A + AdIS spine (T1-sacrum, main thoracic curve 84\u00b0) was created and validated. Six surgical scenarios were simulated: instrumentation-only (M1), Ponte osteotomy alone (M2), and M2 combined with four different PIVR strategies (M3-M6). Simulated corrective forces were applied, and outcomes, including Cobb angle correction and von-Mises stress on vertebrae and implants, were analyzed and compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A targeted 4-level PIVR centered on the apex (M5) achieved the greatest main thoracic curve correction, reducing the Cobb angle from 84\u00b0 to 34.88\u00b0 (a 58.5% correction rate). A more extensive 6-level release (M6) proved less effective (38.99\u00b0, 53.6% correction rate). Model M5 also produced the most significant reduction in peak von-Mises stress on vertebrae (15.9% decrease vs. M2) and pedicle screws (32.9% decrease vs. M2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A selective, 4-level PIVR strategy provides superior deformity correction and a more favorable stress environment than a more extensive release. These findings challenge the \u201cmore is better\u201d paradigm, providing a biomechanical rationale for an \u201coptimal\u201d rather than \u201cmaximal\u201d release approach in severe rigid AdIS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fbioe.2025.1691245","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T06:29:44Z","timestamp":1763965784000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["For severe and rigid adult idiopathic scoliosis, does an optimal extent of posterior intervertebral release exist? 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