{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T16:15:57Z","timestamp":1785860157318,"version":"3.56.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272015"],"award-info":[{"award-number":["82272015"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82572230"],"award-info":[{"award-number":["82572230"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gastric peristalsis plays a pivotal role in regulating gastric emptying and digestive function. However, current clinical assessments of gastric motility primarily rely on invasive or low-temporal-resolution techniques, which fail to support dynamic, real-time evaluations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We innovatively extended the Peristaltic Analyzer (PA)\u2014a high-frame-rate ultrasound technology originally designed for endometrial wave analysis to the assessment of gastric peristalsis. Utilizing submicron displacement tracking and spatiotemporal vector analysis, we conducted real-time visualization and quantitative evaluation of gastric motility in 9 healthy volunteers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All participants completed image acquisition and peristaltic tracking. The detected peristaltic waves consistently propagated from the proximal to the distal stomach, with an average propagation speed of 1.99 \u00b1 0.18\u00a0mm\/s, propagation distance of 3.23 \u00b1 0.33\u00a0cm, peristaltic intensity of 4.76 \u00b1 1.52 (relative units), interval of 17.31 \u00b1 0.86\u00a0s, and frequency of 3.53 \u00b1 0.19\u00a0bpm. Waveforms appeared continuous and rhythmic, with uniform propagation direction and clear spatiotemporal profiles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>As the first application of the PA high-frame-rate peristaltic analysis technology to gastric motility assessment, this study demonstrates its strong potential as a non-invasive and real-time tool for early detection, quantitative monitoring, and clinical evaluation of functional gastrointestinal disorders. PA exhibited superior performance in motion detection, directional analysis, and fine-scale displacement measurement. These capabilities highlight its potential as a novel tool for early identification and longitudinal monitoring of functional gastrointestinal disorders, postoperative gastric dysmotility, and diabetic gastroparesis, offering substantial clinical translational value and applicability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fbioe.2025.1715788","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T06:26:11Z","timestamp":1766125571000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["High-frame-rate ultrasound analysis of gastric peristalsis using the peristaltic analyzer: a pilot feasibility study"],"prefix":"10.3389","volume":"13","author":[{"given":"Li","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanshi","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zijian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1007\/s11739-025-03905-7","article-title":"Ultrasonographic assessment of gastric and gallbladder dynamics in human health and disease","volume":"20","author":"Di Ciaula","year":"2025","journal-title":"Intern. 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