{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:43:12Z","timestamp":1793407392435,"version":"4.5.0"},"reference-count":199,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:p>\n                    Antimicrobial resistance (AMR) continues to escalate worldwide, reducing the effectiveness of existing antibiotics and leading to an urgent need for alternative antimicrobial strategies. Biogenic nanoparticles (BNPs) are nanomaterials synthesized using plants, microorganisms, algae, or isolated biomolecules through biologically mediated processes. These green synthesis routes typically produce nanoparticles that are naturally capped with biological compounds such as phytochemicals, proteins, or polysaccharides, which can influence particle stability, surface chemistry, and biological interactions. The current review summarizes recent advances in the biosynthesis of BNPs, focusing on how biological metabolites regulate metal ion reduction, nucleation, growth, and stabilization, thereby shaping nanoparticle size, morphology, and antimicrobial behavior. BNPs including silver, gold, copper oxide, zinc oxide, iron oxide, titanium dioxide, and selenium have been widely investigated for antibacterial activity. Experimental studies indicate that these materials can act through multiple mechanisms, such as disruption of bacterial membranes, generation of reactive oxygen species, interference with metabolic processes, damage to DNA and proteins, inhibition of quorum sensing, and suppression of biofilm formation. Reported activity spans several WHO-priority and ESKAPE pathogens, largely based on\n                    <jats:italic>in vitro<\/jats:italic>\n                    studies and a limited number of preclinical\n                    <jats:italic>in vivo<\/jats:italic>\n                    models. BNPs have also been explored as adjunct platforms in combination with antibiotics, essential oils, or phytochemicals, where synergistic effects may reduce required drug concentrations and improve activity against resistant strains. In parallel, their physicochemical tunability has supported experimental applications in wound-related systems, antimicrobial coatings, drug delivery research, biosensing, and food-packaging materials. Despite these encouraging findings, major challenges remain. Variability in green synthesis protocols leads to inconsistent physicochemical properties, scalability remains limited, and comprehensive long-term toxicological, pharmacokinetic, and environmental safety data are still lacking. Addressing these issues is essential before BNP-based strategies can progress toward regulatory evaluation and clinical use. In conclusion, biogenic nanoparticles represent a promising but still experimental platform that may contribute to future antimicrobial development if supported by standardized synthesis, rigorous safety assessment, and translational research.\n                  <\/jats:p>","DOI":"10.3389\/fbioe.2026.1752199","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T06:36:30Z","timestamp":1774506990000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Harnessing biogenic nanoparticles for combating antibiotic resistance: green synthesis, mechanistic insights, and biotechnological applications"],"prefix":"10.3389","volume":"14","author":[{"given":"Emad M.","family":"Abdallah","sequence":"first","affiliation":[{"name":"Department of Biology, College of Science, Qassim University","place":["Buraydah, Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman Mohammed","family":"Alhudhaibi","sequence":"additional","affiliation":[{"name":"Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU)","place":["Riyadh, Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim Mohammed","family":"Hussaini","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Life Sciences, Ahmadu Bello University Zaria","place":["Zaria, Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmau Nna","family":"Sulaiman","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Life Sciences, Ahmadu Bello University Zaria","place":["Zaria, Nigeria"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"652362","DOI":"10.3389\/fbioe.2021.652362","article-title":"Synergistic and antagonistic effects of biogenic silver nanoparticles in combination with antibiotics against some pathogenic microbes","volume":"9","author":"Aabed","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/s12917-021-02866-7","article-title":"Antimicrobial and antibiofilm potentials of cinnamon oil and silver nanoparticles against Streptococcus agalactiae isolated from bovine mastitis","volume":"17","author":"Abd El-Aziz","year":"2021","journal-title":"BMC Vet. Res."},{"key":"B3","doi-asserted-by":"publisher","first-page":"3077","DOI":"10.3390\/plants12173077","article-title":"Back to nature: medicinal plants as promising sources for antibacterial drugs in the post-antibiotic era","volume":"12","author":"Abdallah","year":"2023","journal-title":"Plants"},{"key":"B4","doi-asserted-by":"publisher","first-page":"101887","DOI":"10.1016\/j.toxrep.2024","article-title":"Biogenic nanoparticles as a promising drug delivery system","volume":"14","author":"Abdel-Megeed","year":"2025","journal-title":"Toxicol. Rep."},{"key":"B5","doi-asserted-by":"publisher","first-page":"351","DOI":"10.2147\/IDR.S234425","article-title":"Synergistic and antagonistic effects of metal nanoparticles in combination with antibiotics against pathogenic microorganisms","volume":"13","author":"Abo-Shama","year":"2020","journal-title":"Infect. Drug Resist."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.3390\/cryst13111576","article-title":"Green synthesis of nanoparticles and their energy storage, environmental, and biomedical applications","volume":"13","author":"Abuzeid","year":"2023","journal-title":"Crystals"},{"key":"B7","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s10534-024-00642-w","article-title":"Synthesis of metallic nanoparticles using biometabolites: mechanisms and applications","volume":"38","author":"Acharya","year":"2024","journal-title":"Biometals"},{"key":"B9","doi-asserted-by":"publisher","first-page":"627","DOI":"10.3390\/biom12050627","article-title":"Plant-extracts mediated metal-based nanoparticles: synthesis and biological applications","volume":"12","author":"Adeyemi","year":"2022","journal-title":"Biomolecules"},{"key":"B10","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.cbi.2018.03.008","article-title":"Mechanistic study on the antibacterial action of zinc oxide nanoparticles synthesized via green route","volume":"286","author":"Agarwal","year":"2018","journal-title":"Chem.-Biol. Interact."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.3390\/ph17091134","article-title":"Silver and gold nanoparticles as effective antibacterial agents: a comprehensive review","volume":"17","author":"Aguilar-Garay","year":"2024","journal-title":"Pharmaceutics"},{"key":"B12","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.molimm.2017.09.001","article-title":"Targeting dendritic cells through gold nanoparticles: a review of cellular uptake and immunological properties","volume":"91","author":"Ahmad","year":"2017","journal-title":"Mol. Immunol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"14972","DOI":"10.1038\/s41598-023-41502-w","article-title":"Antimicrobial efficacy of mentha piperata-derived biogenic zinc oxide nanoparticles against UTI-Resistant pathogens","volume":"13","author":"Ahmad","year":"2023","journal-title":"Sci. Rep."},{"key":"B14","doi-asserted-by":"publisher","first-page":"2393","DOI":"10.1007\/s10904-021-01915-4","article-title":"Comparative study on antibacterial activity of MgO nanoparticles synthesized from Lawsonia inermis leaves extract and chemical methods","volume":"31","author":"Akshaykranth","year":"2021","journal-title":"J. Inorg. Organomet. Polym. Mat."},{"key":"B15","doi-asserted-by":"publisher","first-page":"945","DOI":"10.3390\/microorganisms11040945","article-title":"Green biofabrication of silver nanoparticles with synergistic antibacterial and antifungal potential","volume":"11","author":"Al-Otibi","year":"2023","journal-title":"Microorganisms"},{"key":"B16","doi-asserted-by":"publisher","first-page":"109590","DOI":"10.1016\/j.inoche.2022.109590","article-title":"Herbal- and bacterial-mediated silver and copper\/copper oxide nanoparticles: antibacterial and photocatalyst properties","volume":"143","author":"Alavi","year":"2022","journal-title":"Inorg. Chem. Commun."},{"key":"B17","doi-asserted-by":"publisher","first-page":"2421","DOI":"10.1038\/s41598-022-06412-3","article-title":"Anticancer and antimicrobial activity of biosynthesized Red Sea marine algal silver nanoparticles","volume":"12","author":"Algotiml","year":"2022","journal-title":"Sci. Rep."},{"key":"B18","doi-asserted-by":"publisher","first-page":"463","DOI":"10.3390\/molecules28010463","article-title":"Plant and microbial approaches as green methods for nanomaterial synthesis: applications and future perspectives","volume":"28","author":"Alsaiari","year":"2023","journal-title":"Molecules"},{"key":"B19","doi-asserted-by":"publisher","first-page":"27","DOI":"10.71146\/kjmr337","article-title":"Nanoparticles in drug delivery: biocompatibility, targeting, and controlled release mechanisms","volume":"2","author":"Anwar","year":"2025","journal-title":"Kashf. J. Multidiscip. Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"4281","DOI":"10.1007\/s42452-021-04281-5","article-title":"Synthesis of TiO2 nanoparticles by chemical and green methods and their multifaceted properties","volume":"3","author":"Aravind","year":"2021","journal-title":"SN Appl. Sci."},{"key":"B21","doi-asserted-by":"publisher","first-page":"14549","DOI":"10.1111\/1751-7915.14549","article-title":"Bacterial synthesis of metal nanoparticles as antimicrobials: a systematic review of resistance mechanisms","volume":"17","author":"Arora","year":"2024","journal-title":"Microb. Biotechnol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s40097-016-0205-2","article-title":"Antibiofilm activity of biogenic copper and zinc oxide nanoparticles-antimicrobials collegiate against multiple drug resistant bacteria: a nanoscale approach","volume":"6","author":"Ashajyothi","year":"2016","journal-title":"J. Nanostructure Chem."},{"key":"B23","doi-asserted-by":"publisher","first-page":"e00913","DOI":"10.1016\/j.btre.2025.e00913","article-title":"Green nanoscience for healthcare: advancing biomedical innovation through eco-synthesized nanoparticle","volume":"47","author":"Ayub","year":"2025","journal-title":"Biotechnol. Rep."},{"key":"B24","doi-asserted-by":"publisher","first-page":"8148","DOI":"10.1038\/s41598-022-12134-3","article-title":"ZnO size and shape effect on antibacterial activity and cytotoxicity profile","volume":"12","author":"Babayevska","year":"2022","journal-title":"Sci. Rep."},{"key":"B25","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s40643-016-0083-y","article-title":"Synergistic antibacterial and antibiofilm activity of silver nanoparticles biosynthesized by Aspergillus flavus and Emericella nidulans","volume":"3","author":"Barapatre","year":"2016","journal-title":"Bioresour. Bioprocess."},{"key":"B26","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.ijbiomac.2018.11.101","article-title":"Facile green synthesis of silver nanoparticles using Berberis vulgaris leaf and root aqueous extract and its antibacterial activity","volume":"124","author":"Behravan","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"668","DOI":"10.3390\/agriculture13030668","article-title":"Green nanotechnology in agro-ecosystems: opportunities for sustainable agriculture and remediation","volume":"13","author":"Bhandari","year":"2023","journal-title":"Agriculture"},{"key":"B28","doi-asserted-by":"publisher","first-page":"4395","DOI":"10.1016\/j.matpr.2015.10.036","article-title":"Bactericidal activity of biologically synthesized silver nanoparticles from Candida albicans combined with ciprofloxacin","volume":"2","author":"Bhat","year":"2015","journal-title":"Mat. Today Proc."},{"key":"B29","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1007\/s00449-025-03190-w","article-title":"Mechanistic pathways and physicochemical influences in microbial synthesis of metallic nanoparticles","volume":"48","author":"Bhatnagar","year":"2025","journal-title":"Bioprocess Biosyst. Eng."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.3390\/molecules27051484","article-title":"Anti-quorum sensing actions of medicinal plant bioactive compounds: mechanisms and clinical evidence","volume":"27","author":"Bouyahya","year":"2022","journal-title":"Molecules"},{"key":"B31","doi-asserted-by":"publisher","first-page":"502","DOI":"10.3390\/antibiotics13060502","article-title":"Artificial intelligence in addressing antimicrobial resistance: innovations and global challenges","volume":"13","author":"Branda","year":"2024","journal-title":"Antibiotics"},{"key":"B32","doi-asserted-by":"publisher","first-page":"7202","DOI":"10.3390\/ijms22137202","article-title":"Silver nanoparticles and their antibacterial applications","volume":"22","author":"Bruna","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"B33","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3390\/polym14010049","article-title":"Bacteriostatic and cytotoxic properties of ZnO\u2013PLGA composites obtained by low-temperature methods","volume":"14","author":"Burmistrov","year":"2021","journal-title":"Polymers"},{"key":"B34","doi-asserted-by":"publisher","first-page":"100413","DOI":"10.1016\/S2213-3437(25)01617-3","article-title":"Sustainable green synthesis of metallic nanoparticle using biological entities towards a circular economy","volume":"5","author":"Cardoso","year":"","journal-title":"Curr. Res. Green Sustain. Chem."},{"key":"B35","doi-asserted-by":"publisher","first-page":"116921","DOI":"10.1016\/j.jece.2025.116921","article-title":"Sustainable green synthesis of metallic nanoparticles using plants and microorganisms: a review of biosynthesis methods, mechanisms, toxicity, and applications","volume":"13","author":"Cardoso","year":"","journal-title":"J. Environ. Chem. Eng."},{"key":"B36","doi-asserted-by":"publisher","first-page":"3113","DOI":"10.1080\/02648725.2022.2106084","article-title":"Biogenic biocompatible silver nanoparticles: a promising antibacterial agent","volume":"40","author":"Chandraker","year":"2022","journal-title":"Biotechnol. Genet. Eng. Rev."},{"key":"B37","doi-asserted-by":"publisher","first-page":"1611126","DOI":"10.3389\/fnano.2025.1611126","article-title":"Antimicrobial nanoparticles: a new horizon to combat multidrug-resistant bacteria","volume":"7","author":"Chaturvedi","year":"2025","journal-title":"Front. Nanotechnol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/s41392-021-00631-2","article-title":"Recent progress in targeted delivery vectors based on biomimetic nanoparticles","volume":"6","author":"Chen","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"B39","doi-asserted-by":"publisher","first-page":"eabo7793","DOI":"10.1126\/scitranslmed.abo7793","article-title":"The past, present, and future of antibiotics","volume":"14","author":"Cook","year":"2022","journal-title":"Sci. Transl. Med."},{"key":"B40","doi-asserted-by":"publisher","first-page":"2641","DOI":"10.1007\/s42770-023-01102-2","article-title":"Biogenic silver nanoparticles: in vitro activity against Staphylococcus aureus methicillin-resistant (MRSA) and multidrug-resistant coagulase-negative staphylococcus (CoNS)","volume":"54","author":"Da Cunha","year":"2023","journal-title":"Braz. J. Microbiol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.colsurfb.2019.02.013","article-title":"Increased antibacterial activity of ZnO nanoparticles: influence of size and surface modification","volume":"177","author":"Da Silva","year":"2019","journal-title":"Colloids Surfaces B Biointerfaces"},{"key":"B42","doi-asserted-by":"publisher","first-page":"e41788","DOI":"10.1371\/journal.pone.0041788","article-title":"A quorum sensing-disrupting brominated thiophenone with a promising therapeutic potential to treat luminescent vibriosis","volume":"7","author":"Defoirdt","year":"2012","journal-title":"PLOS ONE"},{"key":"B43","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1179\/joc.2004.16.Supplement-1.90","article-title":"Liposomal anticancer therapy: pharmacokinetic and clinical aspects","volume":"16","author":"Di paolo","year":"2004","journal-title":"J. Chemotherapy"},{"key":"B44","doi-asserted-by":"publisher","first-page":"731","DOI":"10.3390\/polym12040731","article-title":"Antimicrobial polymer-based materials for food packaging applications","volume":"12","author":"D\u00edez-Pascual","year":"2020","journal-title":"Polymers"},{"key":"B45","doi-asserted-by":"publisher","first-page":"e0222322","DOI":"10.1371\/journal.pone.0222322","article-title":"Antibacterial activity of silver nanoparticles of different particle size against Vibrio natriegens","volume":"14","author":"Dong","year":"2019","journal-title":"PLOS ONE"},{"key":"B46","doi-asserted-by":"publisher","first-page":"111","DOI":"10.5281\/zenodo.8161757","article-title":"Biogenic particles can be multiantigenic, immunostimulative and activate innate immunity while suppressing tumor development","volume":"40","author":"Dowaidar","year":"2023","journal-title":"J. Biomed. Eng."},{"key":"B47","doi-asserted-by":"publisher","first-page":"110","DOI":"10.3390\/microbiolres16060110","article-title":"Silver nanoparticle-based antimicrobial coatings: sustainable strategies for microbial contamination control","volume":"16","author":"Dube","year":"2025","journal-title":"Microbiol. Res."},{"key":"B48","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1049\/iet-nbt.2014.0054","article-title":"Catalytic role of traditional enzymes for biosynthesis of biogenic metallic nanoparticles: a mini-review","volume":"9","author":"Dur\u00e1n","year":"2015","journal-title":"IET Nanobiotechnology"},{"key":"B49","doi-asserted-by":"publisher","first-page":"6222","DOI":"10.3390\/ijms26136222","article-title":"Green synthesis of silver nanoparticles using plant extracts: a comprehensive review of physicochemical properties and multifunctional applications","volume":"26","author":"Eker","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"B50","doi-asserted-by":"publisher","first-page":"24539","DOI":"10.1039\/C9RA02225B","article-title":"Metal nanoparticles fabricated by green chemistry using natural extracts: biosynthesis, mechanisms, and applications","volume":"9","author":"El-Seedi","year":"2019","journal-title":"RSC Adv."},{"key":"B51","doi-asserted-by":"publisher","first-page":"3704","DOI":"10.1039\/C8RA09788G","article-title":"Graphene oxide decorated with zinc oxide nanoflower, silver, and titanium dioxide nanoparticles: fabrication, characterization, DNA interaction, and antibacterial activity","volume":"9","author":"El-Shafai","year":"2019","journal-title":"RSC Adv."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/09603123.2020.1789946","article-title":"Antiviral activity of algae biosynthesized silver and gold nanoparticles against Herpes simplex (HSV-1) virus in vitro using cell-line culture technique","volume":"20","author":"El-Sheekh","year":"2020","journal-title":"Int. J. Environ. Health Res."},{"key":"B54","doi-asserted-by":"publisher","first-page":"101","DOI":"10.3390\/toxics12110801","article-title":"Effect of silver nanoparticle size on antibacterial activity","volume":"12","author":"Ershov","year":"2024","journal-title":"Toxics"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1038\/s41396-018-0047-7","article-title":"Quorum-sensing control of antibiotic resistance stabilizes cooperation in Chromobacterium violaceum","volume":"12","author":"Evans","year":"2018","journal-title":"ISME J."},{"key":"B56","doi-asserted-by":"publisher","first-page":"6988","DOI":"10.3390\/molecules28196988","article-title":"Nanoemulsion of Lavandula angustifolia essential oil\/gold nanoparticles: antibacterial effect against multidrug-resistant wound-causing bacteria","volume":"28","author":"Fadel","year":"2023","journal-title":"Molecules"},{"key":"B57","doi-asserted-by":"publisher","first-page":"100125","DOI":"10.1016\/j.jciso.2024","article-title":"Green synthesis of silver nanoparticles: a comprehensive review of methods, influencing factors, and applications","volume":"16","author":"Fahim","year":"2024","journal-title":"JCIS Open"},{"key":"B58","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s12934-024-02604-w","article-title":"Evaluation of the antibacterial and antibiofilm effect of mycosynthesized silver and selenium nanoparticles and their synergistic effect with antibiotics on nosocomial bacteria","volume":"24","author":"Fahmy","year":"2025","journal-title":"Microb. Cell Factories"},{"key":"B59","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.3390\/pharmaceutics12111110","article-title":"Bactericidal antibacterial mechanism of plant synthesized silver, gold and bimetallic nanoparticles","volume":"12","author":"Fanoro","year":"2020","journal-title":"Pharmaceutics"},{"key":"B60","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.jgar.2016.07.013","article-title":"Extracellular mycosynthesis of silver nanoparticles and their microbicidal activity","volume":"7","author":"F\u00e1tima","year":"2016","journal-title":"J. Glob. Antimicrob. Resist."},{"key":"B61","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.nano.2009.04.006","article-title":"Biogenic synthesis of silver nanoparticles and their synergistic effect with antibiotics: a study against Gram-positive and Gram-negative bacteria","volume":"6","author":"Fayaz","year":"2010","journal-title":"Nanomedicine"},{"key":"B62","doi-asserted-by":"publisher","first-page":"624621","DOI":"10.3389\/fbioe.2020.624621","article-title":"Comparative study of the antimicrobial activity of selenium nanoparticles with different surface chemistry and structure","volume":"8","author":"Filipovi\u0107","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"9998","DOI":"10.3390\/ijms24129998","article-title":"Antimicrobial activity of biogenic metal oxide nanoparticles and their synergistic effect on clinical pathogens","volume":"24","author":"Francis","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"B64","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.3390\/pharmaceutics15041142","article-title":"Alginate-based materials loaded with nanoparticles in wound healing","volume":"15","author":"Froelich","year":"2023","journal-title":"Pharmaceutics"},{"key":"B65","doi-asserted-by":"publisher","first-page":"134680","DOI":"10.1016\/j.jhazmat.2024.134680","article-title":"Berberine and chlorogenic acid-assembled nanoparticles for highly efficient inhibition of multidrug-resistant Staphylococcus aureus","volume":"473","author":"Fu","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"B66","doi-asserted-by":"publisher","first-page":"2773","DOI":"10.1007\/s00253-019-09653-x","article-title":"Antibacterial effects of iron oxide (Fe3O4) nanoparticles: distinguishing concentration-dependent effects with different bacterial cells growth and membrane-associated mechanisms","volume":"103","author":"Gabrielyan","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"14760","DOI":"10.1038\/s41598-020-70211-x","article-title":"Comparable antibacterial effects and action mechanisms of silver and iron oxide nanoparticles on Escherichia coli and Salmonella typhimurium","volume":"10","author":"Gabrielyan","year":"2020","journal-title":"Sci. Rep."},{"key":"B68","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/B978-0-12-824508-8.00008-3","article-title":"Strategies for scaling up of green-synthesized nanomaterials: challenges and future trends","volume-title":"Green synthesis of silver nanomaterials","author":"Gacem","year":"2022"},{"key":"B69","first-page":"323","article-title":"Patents, technology transfer, and commercialization aspects of biogenic nanoparticles","volume-title":"Nanobiotechnology","author":"Ghosh","year":""},{"key":"B70","doi-asserted-by":"publisher","first-page":"638068","DOI":"10.3389\/fmicb.2021.638068","article-title":"Mechanistic aspects of microbe-mediated nanoparticle synthesis","volume":"12","author":"Ghosh","year":"","journal-title":"Front. Microbiol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"3975","DOI":"10.1021\/acs.est.5b05734","article-title":"Shape-dependent surface reactivity and antimicrobial activity of nano-cupric oxide","volume":"50","author":"Gilbertson","year":"2016","journal-title":"Environ. Sci. and Technol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"4470","DOI":"10.1016\/j.bioactmat.2021.04.033","article-title":"Antibacterial approaches in tissue engineering using metal ions and nanoparticles: from mechanisms to applications","volume":"6","author":"Godoy-Gallardo","year":"2021","journal-title":"Bioact. Mater."},{"key":"B73","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.colsurfb.2017.02.020","article-title":"Green synthesis of gold nanoparticles using brown algae cystoseira Baccata: its activity in Colon cancer cells","volume":"153","author":"Gonzalez-Ballesteros","year":"2017","journal-title":"Colloids Surfaces B Biointerfaces"},{"key":"B74","doi-asserted-by":"publisher","first-page":"11563","DOI":"10.3390\/ijms252111563","article-title":"Antibacterial properties of copper oxide nanoparticles","volume":"25","author":"Gudkov","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"B75","doi-asserted-by":"publisher","first-page":"287","DOI":"10.3389\/fbioe.2019.00287","article-title":"Synthesis of silver nanoparticles mediated by fungi: a review","volume":"7","author":"Guilger-Casagrande","year":"2019","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"70528","DOI":"10.3390\/nano15070528","article-title":"Advancements in bio-nanotechnology: green synthesis and emerging applications of bio-nanoparticles","volume":"15","author":"Gunasena","year":"2025","journal-title":"Nanomaterials"},{"key":"B77","doi-asserted-by":"publisher","first-page":"311","DOI":"10.17776\/csj.653627","article-title":"Fungus-mediated synthesis of silver nanoparticles (AgNP) and inhibitory effect on aspergillus spp. in combination with antifungal agent","volume":"41","author":"Gursoy","year":"2020","journal-title":"Cumhuriyet Sci. J."},{"key":"B78","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.glohj.2023.02.008","article-title":"Applications of nanotechnology in medical field: a brief review","volume":"7","author":"Haleem","year":"2023","journal-title":"Glob. Health J."},{"key":"B79","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.sjbs.2017.09.004","article-title":"The intertwine of nanotechnology with the food industry","volume":"25","author":"Hamad","year":"2018","journal-title":"Saudi J. Biol. Sci."},{"key":"B80","doi-asserted-by":"publisher","first-page":"1337543","DOI":"10.3389\/fbioe.2023.1337543","article-title":"Synergistic antibacterial mechanism of silver-copper bimetallic nanoparticles","volume":"11","author":"Hao","year":"2024","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B81","doi-asserted-by":"publisher","first-page":"e61654","DOI":"10.5812\/pedinfect.61654","article-title":"The synergic activity of eucalyptus leaf oil and silver nanoparticles against some pathogenic bacteria","volume":"5","author":"Heydari","year":"2017","journal-title":"Archives Pediatr. Infect. Dis."},{"key":"B83","doi-asserted-by":"publisher","first-page":"239","DOI":"10.3389\/fbioe.2019.00239","article-title":"Investigation of the antibacterial activity and in vivo cytotoxicity of biogenic silver nanoparticles as potent therapeutics","volume":"7","author":"Hossain","year":"2019","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B84","doi-asserted-by":"publisher","first-page":"14937","DOI":"10.1039\/C9NR04424H","article-title":"Engineering highly effective antimicrobial selenium nanoparticles through control of particle size","volume":"11","author":"Huang","year":"2019","journal-title":"Nanoscale"},{"key":"B85","doi-asserted-by":"publisher","first-page":"8732","DOI":"10.1021\/acsnano.6b04207","article-title":"Fully zwitterionic nanoparticle antimicrobial agents through tuning of core size and ligand structure","volume":"10","author":"Huo","year":"2016","journal-title":"ACS Nano"},{"key":"B86","doi-asserted-by":"publisher","first-page":"100082","DOI":"10.1016\/j.onano.2022.100082","article-title":"Synthesis, photocatalytic degradation and antibacterial properties of selenium or silver doped zinc oxide nanoparticles: a detailed review","volume":"7","author":"Ifijen","year":"2022","journal-title":"Open Nano."},{"key":"B87","doi-asserted-by":"publisher","first-page":"e202300867","DOI":"10.1002\/cbic.202300867","article-title":"Peptide-conjugated nanoparticle platforms for targeted delivery, imaging, and biosensing applications","volume":"25","author":"Ilie\u015f","year":"2024","journal-title":"ChemBioChem"},{"key":"B88","doi-asserted-by":"publisher","first-page":"2638","DOI":"10.1039\/C1GC15386B","article-title":"Green synthesis of metal nanoparticles using plants","volume":"13","author":"Iravani","year":"2011","journal-title":"Green Chem."},{"key":"B89","doi-asserted-by":"publisher","first-page":"2001284","DOI":"10.1002\/adfm.202001284","article-title":"Layer-by-layer coating of amino cellulose and quorum quenching acylase on silver nanoparticles synergistically eradicate bacteria and their biofilms","volume":"30","author":"Ivanova","year":"2020","journal-title":"Adv. Funct. Mater."},{"key":"B90","doi-asserted-by":"publisher","first-page":"e202400701","DOI":"10.1002\/asia.202400701","article-title":"Rethinking nanoparticle synthesis: a sustainable approach vs. traditional methods","volume":"19","author":"Jain","year":"2024","journal-title":"Chem. Asian J."},{"key":"B91","doi-asserted-by":"publisher","first-page":"102298","DOI":"10.1016\/j.fochx.2025.102298","article-title":"Advancing food safety with biogenic silver nanoparticles: addressing antimicrobial resistance, sustainability, and commercial viability","volume":"26","author":"Jangid","year":"2025","journal-title":"Food Chem. X"},{"key":"B92","doi-asserted-by":"publisher","first-page":"7595","DOI":"10.1039\/C6NR09500C","article-title":"Nanoparticle-induced oxidation of Corona proteins initiates an oxidative stress response in cells","volume":"9","author":"Jayaram","year":"2017","journal-title":"Nanoscale"},{"key":"B93","doi-asserted-by":"publisher","first-page":"100940","DOI":"10.1016\/j.lanmic.2024.07.003","article-title":"WHO publishes updated list of bacterial priority pathogens","volume":"5","author":"Jesudason","year":"2024","journal-title":"Lancet Microbe"},{"key":"B94","doi-asserted-by":"publisher","first-page":"3104","DOI":"10.3390\/molecules30153104","article-title":"Biogenic synthesis of silver nanoparticles and their diverse biomedical applications","volume":"30","author":"Jiang","year":"2025","journal-title":"Molecules"},{"key":"B95","doi-asserted-by":"publisher","first-page":"4927","DOI":"10.1039\/C7NR08499D","article-title":"Unexpected insights into antibacterial activity of zinc oxide nanoparticles against methicillin-resistant Staphylococcus aureus (MRSA)","volume":"10","author":"Kadiyala","year":"2018","journal-title":"Nanoscale"},{"key":"B96","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.arabjc.2017.05.011","article-title":"Nanoparticles: properties, applications and toxicities","volume":"12","author":"Khan","year":"2019","journal-title":"Arabian J. Chem."},{"key":"B97","doi-asserted-by":"publisher","first-page":"673","DOI":"10.3390\/nano12040673","article-title":"Green nanotechnology: plant-mediated nanoparticle synthesis and application","volume":"12","author":"Khan","year":"2022","journal-title":"Nanomaterials"},{"key":"B98","doi-asserted-by":"publisher","first-page":"2031","DOI":"10.1007\/s12010-023-04630-7","article-title":"Anti pathogenic efficacy of biogenic silver nanoparticles and antibiofilm activities against multi-drug-resistant ESKAPE pathogens","volume":"196","author":"Khan","year":"2023","journal-title":"Appl. Biochem. Biotechnol."},{"key":"B99","doi-asserted-by":"publisher","first-page":"101258","DOI":"10.1016\/j.rechem.2023.101258","article-title":"Nano-sized copper particles: chemical synthesis, characterization, and their size and surface charge dependent antibacterial potential","volume":"6","author":"Khatoon","year":"2024","journal-title":"Results Chem."},{"key":"B100","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s10534-008-9159-2","article-title":"Antifungal activity and mode of action of silver nano-particles on Candida albicans","volume":"22","author":"Kim","year":"2009","journal-title":"Biometals"},{"key":"B101","doi-asserted-by":"publisher","first-page":"2489","DOI":"10.3390\/molecules27082489","article-title":"Antibacterial mechanisms of zinc oxide nanoparticle against bacterial food pathogens resistant to beta-lactam antibiotics","volume":"27","author":"Krishnamoorthy","year":"2022","journal-title":"Molecules"},{"key":"B102","doi-asserted-by":"publisher","first-page":"227","DOI":"10.2147\/NSA.S489407","article-title":"The substantial role of cell and nanoparticle surface properties in the antibacterial potential of spherical silver nanoparticles","volume":"17","author":"Krychowiak-Ma\u015bnicka","year":"2024","journal-title":"Nanotechnol. Sci. Appl."},{"key":"B103","doi-asserted-by":"publisher","first-page":"1175149","DOI":"10.3389\/fnano.2023.1175149","article-title":"Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products","volume":"5","author":"Kumar","year":"2023","journal-title":"Front. Nanotechnol."},{"key":"B104","doi-asserted-by":"publisher","first-page":"11321","DOI":"10.2147\/IJN.S485588","article-title":"Collagen-based nanoparticles as drug delivery system in wound healing applications","volume":"19","author":"Kusnadi","year":"2024","journal-title":"Int. J. Nanomedicine"},{"key":"B105","doi-asserted-by":"publisher","first-page":"636588","DOI":"10.3389\/fmicb.2021.636588","article-title":"Microbiologically synthesized nanoparticles and their role in silencing the biofilm signaling Cascade","volume":"12","author":"Lahiri","year":"2021","journal-title":"Front. Microbiol."},{"key":"B106","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.3389\/fphar.2019.01153","article-title":"Nanoparticles in the treatment of infections caused by multidrug-resistant organisms","volume":"10","author":"Lee","year":"2019","journal-title":"Front. Pharmacol."},{"key":"B107","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.2147\/IJN.S191340","article-title":"Antibacterial activity and mechanism of silver nanoparticles against multidrug-resistant Pseudomonas aeruginosa","volume":"14","author":"Liao","year":"2019","journal-title":"Int. J. Nanomedicine"},{"key":"B108","doi-asserted-by":"publisher","first-page":"1456939","DOI":"10.3389\/fnano.2024.1456939","article-title":"Recent advances in surface decoration of nanoparticles in drug delivery","volume":"6","author":"Ly","year":"2024","journal-title":"Front. Nanotechnol."},{"key":"B109","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin. Microbiol. Infect."},{"key":"B110","doi-asserted-by":"publisher","first-page":"32484","DOI":"10.1038\/s41598-025-18967-y","article-title":"Antibacterial synergistic behaviour of phytosynthesized magnesium oxide nanoparticles with clove essential oil","volume":"15","author":"Manaa","year":"2025","journal-title":"Sci. Rep."},{"key":"B111","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.micpath.2015.11.021","article-title":"Antibacterial, antibiofilm, and cytotoxic effects of Nigella sativa essential oil-coated gold nanoparticles","volume":"91","author":"Manju","year":"2016","journal-title":"Microb. Pathog."},{"key":"B112","doi-asserted-by":"publisher","first-page":"e51437","DOI":"10.1002\/app.51437","article-title":"The effects of ionic strength and pH on antibacterial activity of hybrid biosurfactant\u2013biopolymer nanoparticles","volume":"138","author":"Marangon","year":"2021","journal-title":"J. Appl. Polym. Sci."},{"key":"B113","doi-asserted-by":"publisher","first-page":"12973","DOI":"10.1021\/acs.nanolett.4c03668","article-title":"The synergy between antibiotics and the nanoparticle-based photodynamic effect","volume":"24","author":"Marfavi","year":"2024","journal-title":"Nano Lett"},{"key":"B114","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1080\/10590501.2015.1055165","article-title":"Synergistic antibacterial effect of silver nanoparticles combined with ineffective antibiotics on drug-resistant Salmonella typhimurium DT104. Journal of environmental science and health","volume":"33","author":"McShan","year":"2015","journal-title":"Part C"},{"key":"B115","doi-asserted-by":"publisher","first-page":"11732","DOI":"10.1038\/s41598-022-06657-y","article-title":"Antibacterial action and target mechanisms of zinc oxide nanoparticles against bacterial pathogens","volume":"12","author":"Mendes","year":"2021","journal-title":"Sci. Rep."},{"key":"B116","doi-asserted-by":"publisher","first-page":"638","DOI":"10.3390\/nano14070638","article-title":"Optimizing antimicrobial efficacy: investigating the impact of zinc oxide nanoparticle shape and size","volume":"14","author":"Mendes","year":"2024","journal-title":"Nanomaterials"},{"key":"B117","doi-asserted-by":"publisher","first-page":"204","DOI":"10.3390\/jfb14050244","article-title":"Effect of size, shape and surface functionalization on the antibacterial activity of silver nanoparticles","volume":"14","author":"Menichetti","year":"2023","journal-title":"J. Funct. Biomaterials"},{"key":"B118","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1146\/annurev.micro.55.1.165","article-title":"Quorum sensing in bacteria","volume":"55","author":"Miller","year":"2001","journal-title":"Annu. Rev. Microbiol."},{"key":"B119","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.3390\/nano11071774","article-title":"A machine learning tool to predict the antibacterial capacity of nanoparticles","volume":"11","author":"Mirzaei","year":"2021","journal-title":"Nanomaterials"},{"key":"B120","doi-asserted-by":"publisher","first-page":"113826","DOI":"10.1016\/j.colsurfb.2024.113826","article-title":"Novel silver nanoparticle-antibiotic combinations as promising antibacterial and anti-biofilm candidates against multiple-antibiotic resistant ESKAPE microorganisms","volume":"236","author":"Mishra","year":"2024","journal-title":"Colloids Surfaces B Biointerfaces"},{"key":"B121","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s40097-018-0257-6","article-title":"Influence of temperature and concentration on biosynthesis and characterization of zinc oxide nanoparticles using cherry extract","volume":"8","author":"Mohammadi","year":"2018","journal-title":"J. Nanostructure Chem."},{"key":"B122","doi-asserted-by":"publisher","first-page":"53","DOI":"10.3390\/pharmaceutics9040053","article-title":"An overview of chitosan nanoparticles and its application in non-parenteral drug delivery","volume":"9","author":"Mohammed","year":"2017","journal-title":"Pharmaceutics"},{"key":"B123","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1039\/D4PM00032C","article-title":"Antimicrobial nanoparticles: current landscape and future perspectives","volume":"1","author":"Mondal","year":"2024","journal-title":"Polym. Chem."},{"key":"B124","doi-asserted-by":"publisher","first-page":"e21234","DOI":"10.1016\/j.heliyon.2023.e22105","article-title":"Recent advance on nanoparticles or nanomaterials with anti-multidrug resistant bacteria and anti-bacterial biofilm properties: a systematic review","volume":"9","author":"Moradi","year":"2023","journal-title":"Heliyon"},{"key":"B125","doi-asserted-by":"publisher","first-page":"M675","DOI":"10.1111\/1750-3841.12400","article-title":"Incorporation of essential oils and nanoparticles in pullulan films to control foodborne pathogens on meat and poultry products","volume":"79","author":"Morsy","year":"2014","journal-title":"J. Food Sci."},{"key":"B126","doi-asserted-by":"publisher","first-page":"2470","DOI":"10.3390\/pharmaceutics15102470","article-title":"Antibacterial activity of zinc oxide nanoparticles loaded with essential oils","volume":"15","author":"Motelic\u0103","year":"2023","journal-title":"Pharmaceutics"},{"key":"B127","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1007\/s00284-025-04064-w","article-title":"A comprehensive review on exploring the potential of phytochemicals and biogenic nanoparticles for the treatment of antimicrobial-resistant pathogenic bacteria","volume":"82","author":"Murugan","year":"2025","journal-title":"Curr. Microbiol."},{"key":"B128","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1080\/17458080.2022.2084533","article-title":"Synergy of green-synthesized silver nanoparticles and Vatica diospyroides fruit extract in inhibiting Gram-positive bacteria by inducing membrane and intracellular disruption","volume":"17","author":"Musimun","year":"2022","journal-title":"J. Exp. Nanosci."},{"key":"B129","doi-asserted-by":"publisher","first-page":"674","DOI":"10.3390\/antibiotics13070674","article-title":"Synergistic antimicrobial activity of biogenic silver nanoparticles and Acanthospermum australe essential oil against skin infection pathogens","volume":"13","author":"Mussin","year":"2024","journal-title":"Antibiotics"},{"key":"B130","doi-asserted-by":"publisher","first-page":"1000864","DOI":"10.1016\/S2405-8440(21)00086-4","article-title":"Effect of silver nanoparticles on salt tolerance of Satureja hortensis L","volume":"2","author":"Nejatzadeh","year":"2021","journal-title":"Plant Commun."},{"key":"B131","doi-asserted-by":"publisher","first-page":"132271","DOI":"10.1016\/j.chemosphere.2021.132271","article-title":"Novel biogenic silver and gold nanoparticles for multifunctional applications: green synthesis, catalytic and antibacterial activity, and colorimetric detection of Fe(III) ions","volume":"287","author":"Nguyen","year":"2021","journal-title":"Chemosphere"},{"key":"B132","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.3390\/pharmaceutics15061650","article-title":"Updates on biogenic metallic and metal oxide nanoparticles: therapy, drug delivery and cytotoxicity","volume":"15","author":"Nikolova","year":"2023","journal-title":"Pharmaceutics"},{"key":"B133","doi-asserted-by":"publisher","first-page":"100609","DOI":"10.1016\/j.fbio.2020.100609","article-title":"Enhancement of food shelf life with polyvinyl alcohol\u2013chitosan nanocomposite films from bioactive eucalyptus leaf extracts","volume":"36","author":"Nwabor","year":"2020","journal-title":"Food Biosci."},{"key":"B134","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s10098-024-02966-0","article-title":"Biogenic synthesis of metal nanoparticles: promoting green nanotechnology and sustainable development goals","volume":"27","author":"Nyandoro","year":"2024","journal-title":"Clean Technol. Environ. Policy"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.4314\/tjpr.v8i3.44546","article-title":"Nanotechnology and drug delivery part 1: background and applications","volume":"8","author":"Ochekpe","year":"2009","journal-title":"Trop. J. Pharm. Res."},{"key":"B135","doi-asserted-by":"publisher","first-page":"2428","DOI":"10.1111\/1541-4337.12727","article-title":"Antimicrobial nanoparticles and biodegradable polymer composites for active food packaging applications","volume":"20","author":"Omerovi\u0107","year":"2021","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"B136","doi-asserted-by":"publisher","first-page":"237","DOI":"10.22038\/nmj.2017.04.006","article-title":"Synergistic antibacterial activity of medicinal plant essential oils with biogenic silver nanoparticles","volume":"4","author":"Oroojalian","year":"2017","journal-title":"Nanomedicine J."},{"key":"B137","doi-asserted-by":"publisher","first-page":"1712","DOI":"10.1128\/AEM.02218-06","article-title":"Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle?","volume":"73","author":"Pal","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"B138","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/978-3-031-50093-0_7","article-title":"Biogenic TiO2 nanoparticles for advanced antimicrobial and antiviral applications","volume-title":"Nanoparticles in modern antimicrobial and antiviral applications","author":"Pandya","year":"2024"},{"key":"B139","doi-asserted-by":"publisher","first-page":"207","DOI":"10.3390\/antibiotics14020207","article-title":"Nanomaterial-based strategies to combat antibiotic resistance","volume":"14","author":"Parvin","year":"2025","journal-title":"Antibiotics"},{"key":"B140","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/s43141-020-00081-3","article-title":"Biogenic nanoparticles: a comprehensive perspective in synthesis, characterization, application and its challenges","volume":"18","author":"Patil","year":"2020","journal-title":"J. Genet. Eng. Biotechnol."},{"key":"B141","doi-asserted-by":"publisher","first-page":"731","DOI":"10.3390\/biom15050731","article-title":"Silver nanoparticles (AgNPs) from lysinibacillus sp. culture broths: antibacterial activity, mechanism insights, and synergy with classical antibiotics","volume":"15","author":"Pernas-Pleite","year":"2025","journal-title":"Biomolecules"},{"key":"B142","doi-asserted-by":"publisher","first-page":"486","DOI":"10.3390\/coatings13030486","article-title":"Biosensors in food and healthcare industries: bio-coatings based on biogenic nanoparticles and biopolymers","volume":"13","author":"Popescu","year":"2023","journal-title":"Coatings"},{"key":"B143","doi-asserted-by":"publisher","first-page":"9155","DOI":"10.1021\/acs.langmuir.5b02266","article-title":"Insight into the mechanism of antibacterial activity of ZnO: surface defects mediated reactive oxygen species Even in the dark","volume":"31","author":"Prasanna","year":"2015","journal-title":"Langmuir"},{"key":"B144","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1021\/nn700194h","article-title":"Cobalt ferrite nanocrystals: out-performing magnetotactic bacteria","volume":"1","author":"Prozorov","year":"2007","journal-title":"ACS Nano"},{"key":"B145","doi-asserted-by":"publisher","first-page":"4649506","DOI":"10.1155\/2019\/4649506","article-title":"Antibacterial effect of silver nanoparticles synthesized using Murraya koenigii (L.) against multidrug-resistant pathogens","volume":"2019","author":"Qais","year":"2019","journal-title":"Bioinorganic Chem. Appl."},{"key":"B146","doi-asserted-by":"publisher","first-page":"15397","DOI":"10.3390\/ijms242015397","article-title":"Green synthesis of metal and metal oxide nanoparticles: a review of the principles and biomedical applications","volume":"24","author":"Radulescu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"B147","article-title":"Nanoparticle synthesis, applications, and toxicity","volume-title":"Applications of nanobiotechnology","author":"Rahimi","year":"2019"},{"key":"B148","doi-asserted-by":"publisher","first-page":"e0268184","DOI":"10.1371\/journal.pone.0268184","article-title":"Green synthesis of SiO2 nanoparticles from rhus Coriaria L. extract: comparison with chemically synthesized SiO2 nanoparticles","volume":"17","author":"Rahimzadeh","year":"2022","journal-title":"PLOS ONE"},{"key":"B149","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.ijpharm.2017.01.013","article-title":"Synergistic antimicrobial potential of essential oils in combination with nanoparticles: emerging trends and future perspectives","volume":"519","author":"Rai","year":"2017","journal-title":"Int. J. Pharm."},{"key":"B150","doi-asserted-by":"publisher","first-page":"129440","DOI":"10.1016\/j.molstruc.2020.129440","article-title":"Cytotoxicity behaviour of response surface model optimized gold nanoparticles by utilizing fucoidan extracted from padina Tetrastromatica","volume":"1228","author":"Rajeshkumar","year":"2021","journal-title":"J. Mol. Struct."},{"key":"B151","doi-asserted-by":"publisher","first-page":"4963","DOI":"10.1021\/acsami.6b00161","article-title":"Antibacterial effects of biosynthesized silver nanoparticles on surface ultrastructure and nanomechanical properties of Gram-negative bacteria viz. Escherichia coli and Pseudomonas aeruginosa","volume":"8","author":"Ramalingam","year":"2016","journal-title":"ACS Appl. Mater. and Interfaces"},{"key":"B152","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/j.ijantimicag.2008.12.004","article-title":"Characterisation of copper oxide nanoparticles for antimicrobial applications","volume":"33","author":"Ren","year":"2009","journal-title":"Int. Journal Antimicrobial Agents"},{"key":"B153","doi-asserted-by":"publisher","first-page":"19615","DOI":"10.1038\/s41598-020-76726-7","article-title":"Synergistic effects of combinatorial chitosan and polyphenol biomolecules on enhanced antibacterial activity of bio functionalized silver nanoparticles","volume":"10","author":"Rezazadeh","year":"2020","journal-title":"Sci. Rep."},{"key":"B154","doi-asserted-by":"publisher","first-page":"3030","DOI":"10.1021\/acsanm.1c03891","article-title":"Synergistic effects between metal nanoparticles and commercial antimicrobial agents: a review","volume":"5","author":"Ribeiro","year":"2022","journal-title":"ACS Appl. Nano Mater."},{"key":"B155","doi-asserted-by":"publisher","first-page":"26","DOI":"10.30750\/ijpbr.8.3.4","article-title":"Yeast-mediated green synthesis of nanoparticles for biological applications","volume":"8","author":"Roychoudhury","year":"2020","journal-title":"Indian J. Pharm. Biol. Res."},{"key":"B156","doi-asserted-by":"publisher","first-page":"292","DOI":"10.3390\/nano10020292","article-title":"Metal-based nanoparticles as antimicrobial agents: an overview","volume":"10","author":"S\u00e1nchez-L\u00f3pez","year":"2020","journal-title":"Nanomaterials"},{"key":"B157","doi-asserted-by":"publisher","first-page":"842600","DOI":"10.3389\/fmicb.2022.842600","article-title":"Biogenic silver nanoparticles strategically combined with Origanum vulgare derivatives: antibacterial mechanism of action and effect on multidrug-resistant strains","volume":"13","author":"Scandorieiro","year":"2022","journal-title":"Front. Microbiology"},{"key":"B158","doi-asserted-by":"publisher","first-page":"756","DOI":"10.3390\/antibiotics12040756","article-title":"Anti-biofilm effect of biogenic silver nanoparticles combined with oregano derivatives against carbapenem-resistant Klebsiella pneumoniae","volume":"12","author":"Scandorieiro","year":"2023","journal-title":"Antibiotics"},{"key":"B159","doi-asserted-by":"publisher","first-page":"2448171","DOI":"10.1080\/17518253.2024.2448171","article-title":"Nature\u2019s nanofactories: biogenic synthesis of metal nanoparticles for sustainable technologies","volume":"18","author":"Shah","year":"2025","journal-title":"Green Chem. Lett. Rev."},{"key":"B160","doi-asserted-by":"publisher","first-page":"3858","DOI":"10.1039\/D4RA07519F","article-title":"A review on green synthesis of silver nanoparticles (SNPs) using plant extracts: a multifaceted approach in photocatalysis, environmental remediation, and biomedicine","volume":"15","author":"Shahzadi","year":"2025","journal-title":"RSC Adv."},{"key":"B161","doi-asserted-by":"publisher","first-page":"33303","DOI":"10.1021\/acsomega.4c02822","article-title":"Influence of physicochemical properties of iron oxide nanoparticles on their antibacterial activity","volume":"9","author":"Shoudho","year":"2024","journal-title":"ACS Omega"},{"key":"B162","doi-asserted-by":"publisher","first-page":"100327","DOI":"10.1016\/j.mtchem.2020.100327","article-title":"Sustainable preparation of gold nanoparticles via green chemistry approach for biogenic applications","volume":"17","author":"Si","year":"2020","journal-title":"Mater. Today Chem."},{"key":"B163","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1039\/D2MH01117D","article-title":"Elucidating the role of multivalency, shape, size and functional group density on antibacterial activity of diversified supramolecular nanostructures enabled by templated assembly","volume":"10","author":"Sikder","year":"2022","journal-title":"Mater. Horizons"},{"key":"B164","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3390\/antibiotics7040093","article-title":"Antimicrobial silver in medicinal and consumer applications: a patent review of the past decade (2007\u20132017)","volume":"7","author":"Sim","year":"2018","journal-title":"Antibiotics"},{"key":"B165","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/j.tibtech.2016.02.006","article-title":"Biological synthesis of nanoparticles from plants and microorganisms","volume":"34","author":"Singh","year":"2016","journal-title":"Trends Biotechnol."},{"key":"B166","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.3390\/nano8121009","article-title":"Antimicrobial effects of biogenic nanoparticles","volume":"8","author":"Singh","year":"2018","journal-title":"Nanomaterials"},{"key":"B167","doi-asserted-by":"publisher","first-page":"4727","DOI":"10.2147\/IJN.S419369","article-title":"Revisiting the green synthesis of nanoparticles: uncovering influences of plant extracts as reducing agents for enhanced synthesis efficiency and its biomedical applications","volume":"18","author":"Singh","year":"2023","journal-title":"Int. J. Nanomedicine"},{"key":"B168","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/s40820-015-0040-x","article-title":"Review on zinc oxide nanoparticles: antibacterial activity and toxicity mechanism","volume":"7","author":"Sirelkhatim","year":"2015","journal-title":"Nano-micro Letters"},{"key":"B169","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1007\/s00430-016-0477-7","article-title":"Evaluating cytotoxicity, immune compatibility and antibacterial activity of biogenic silver nanoparticles","volume":"205","author":"Sk\u0142adanowski","year":"2016","journal-title":"Med. Microbiol. Immunol."},{"key":"B170","first-page":"1999","article-title":"Real-time vital optical imaging of precancer using anti-epidermal growth factor receptor antibodies conjugated to gold nanoparticles","volume":"63","author":"Sokolov","year":"2003","journal-title":"Cancer Research"},{"key":"B171","doi-asserted-by":"publisher","first-page":"11659","DOI":"10.1039\/D1RA00187F","article-title":"Algae-mediated route to biogenic cuprous oxide nanoparticles: physico-chemical characterisation and antibacterial activities","volume":"11","author":"Soureshjani","year":"2021","journal-title":"RSC Adv."},{"key":"B172","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1007\/s12668-021-00824-7","article-title":"Comparative study on the synthesis, characterization, and antioxidant activity of green and chemically synthesized silver nanoparticles","volume":"11","author":"Sreelekha","year":"2021","journal-title":"BioNanoScience"},{"key":"B173","doi-asserted-by":"publisher","first-page":"9","DOI":"10.25130\/tjps.v30i1.1692","article-title":"Bioactivity of gold nanoparticles synthesized from lion's mushroom on multidrug-resistant (MDR) ESKAPE bacterial isolates","volume":"30","author":"Sultan","year":"2025","journal-title":"Tikrit J. Pure Sci"},{"key":"B174","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1007\/s10904-023-02935-y","article-title":"Mode of action of biogenic silver, zinc, copper, titanium and cobalt nanoparticles against antibiotics resistant pathogens","volume":"34","author":"Summer","year":"2024","journal-title":"J. Inorg. Organomet. Polym. Mater."},{"key":"B175","doi-asserted-by":"publisher","first-page":"10225","DOI":"10.1016\/j.ceramint.2023.12.332","article-title":"Citrus Sinensis assisted biogenic synthesis and physicochemical properties of Fe3O4 nanoparticles for antibacterial activity","volume":"50","author":"Susithra","year":"2023","journal-title":"Ceram. Int."},{"key":"B176","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1007\/s12088-023-01136-y","article-title":"Antibacterial potential of biosynthesized silver nanoparticles using berberine extract against multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa","volume":"63","author":"Tahan","year":"2023","journal-title":"Indian J. Microbiol."},{"key":"B177","doi-asserted-by":"publisher","first-page":"1029056","DOI":"10.3389\/fchem.2022.1029056","article-title":"Synergistic and antibiofilm potential of Curcuma aromatica derived silver nanoparticles in combination with antibiotics against multidrug-resistant pathogens","volume":"10","author":"Tawre","year":"2022","journal-title":"Front. Chem."},{"key":"B178","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s10876-024-02728-4","article-title":"Nano\u2013bio interaction and antibacterial mechanism of engineered metal nanoparticles: fundamentals and current understanding","volume":"36","author":"Tiwari","year":"2024","journal-title":"J. Clust. Sci."},{"key":"B179","doi-asserted-by":"publisher","first-page":"163912","DOI":"10.1016\/j.scitotenv.2023.163912","article-title":"Biobased: biostimulants and biogenic nanoparticles enter the scene","volume":"885","author":"Tolisano","year":"2023","journal-title":"Sci. Total Environ."},{"key":"B180","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/978-3-031-65986-7_8","article-title":"Multi-omics approaches to resolve antimicrobial resistance","volume-title":"Antimicrobial resistance: factors to findings \u2014 omics and systems biology approaches","author":"Tran","year":"2024"},{"key":"B181","doi-asserted-by":"publisher","first-page":"9","DOI":"10.15421\/012002","article-title":"Bacterial synthesis of nanoparticles: a green approach","volume":"28","author":"Tsekhmistrenko","year":"2020","journal-title":"Biosyst. Divers."},{"key":"B182","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/2228-5326-2-9","article-title":"Chemical synthesis and antibacterial activity of novel-shaped silver nanoparticles","volume":"2","author":"Van Dong","year":"2012","journal-title":"Int. Nano Lett."},{"key":"B183","doi-asserted-by":"publisher","first-page":"9931","DOI":"10.1038\/s41598-023-36460-2","article-title":"Synergistic antibacterial effect of copper and silver nanoparticles and their mechanism of action","volume":"13","author":"Vasiliev","year":"2023","journal-title":"Sci. Rep."},{"key":"B184","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-95390-8_21","article-title":"Selenium nanoparticles: biomedical applications","author":"Vinkovi\u0107 Vr\u010dek","year":"2018","journal-title":"Selenium. Molecular and Integrative Toxicology"},{"key":"B185","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/s44222-024-00264-4","article-title":"Multi-omics approaches to decipher the interactions of nanoparticles and biological systems","volume":"3","author":"Wang","year":"","journal-title":"Nat. Rev. Bioeng."},{"key":"B186","doi-asserted-by":"publisher","first-page":"2416594","DOI":"10.1002\/adfm.202416594","article-title":"Selective adsorption to pathogenic bacteria augments antibacterial activity via adjusting the physicochemical property of nanoparticles","volume":"35","author":"Wang","year":"","journal-title":"Adv. Funct. Mater."},{"key":"B187","volume-title":"WHO bacterial priority pathogens list, 2024: bacterial pathogens of public health importance to guide research, development and strategies to prevent and control antimicrobial resistance","year":"2024"},{"key":"B188","doi-asserted-by":"publisher","first-page":"7921","DOI":"10.3390\/molecules28237921","article-title":"The synergistic effect of biosynthesized silver nanoparticles and phytocompound as a novel approach to the elimination of pathogens","volume":"28","author":"Wro\u0144ska","year":"2023","journal-title":"Molecules"},{"key":"B189","doi-asserted-by":"publisher","first-page":"4831","DOI":"10.2147\/IJN.S315839","article-title":"Enhanced antibacterial and anti-biofilm activities of antimicrobial peptides modified silver nanoparticles","volume":"16","author":"Xu","year":"2021","journal-title":"Int. J. Nanomedicine"},{"key":"B190","doi-asserted-by":"publisher","first-page":"423","DOI":"10.2174\/0115734137301010240507101533","article-title":"Antibacterial activities of copper, silver, and zinc-derived nanoparticles and their capacity to enhance the antimicrobial activities of antibiotics","volume":"21","author":"Yancey-Gray","year":"2025","journal-title":"Curr. Nanosci."},{"key":"B191","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.3390\/cryst12081057","article-title":"Synergistic antibacterial activity of green synthesized silver nanomaterials with colistin antibiotic against multidrug-resistant bacterial pathogens","volume":"12","author":"Yassin","year":"2022","journal-title":"Crystals"},{"key":"B192","doi-asserted-by":"publisher","first-page":"15444","DOI":"10.1038\/s41598-023-42756-0","article-title":"Dandelion flower-fabricated Ag nanoparticles versus synthetic ones with characterization and determination of photocatalytic, antioxidant, antibacterial, and \u03b1-glucosidase inhibitory activities","volume":"13","author":"Yousefzadeh-Valendeh","year":"2023","journal-title":"Sci. Rep."},{"key":"B193","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.carbpol.2015.06.075","article-title":"Evaluation of bionanocomposites as packaging material on properties of soft white cheese during storage period","volume":"132","author":"Youssef","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"B194","doi-asserted-by":"publisher","first-page":"329","DOI":"10.3390\/gels8060329","article-title":"Nanoparticle-containing wound dressing: antimicrobial and healing effects","volume":"8","author":"Yudaev","year":"2022","journal-title":"Gels"},{"key":"B195","doi-asserted-by":"publisher","first-page":"113912","DOI":"10.1016\/j.jpba.2021.113912","article-title":"Determination of paracetamol using a sensor based on green synthesis of silver nanoparticles in plant extract","volume":"196","author":"Zamarchi","year":"2021","journal-title":"J. Pharm. Biomed. Analysis"},{"key":"B196","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1007\/s40005-022-00584-w","article-title":"Controlled release and targeted drug delivery with poly(lactic-co-glycolic acid) nanoparticles: reviewing two decades of research","volume":"52","author":"Zeb","year":"2022","journal-title":"J. Pharm. Investigation"},{"key":"B197","doi-asserted-by":"publisher","first-page":"104747","DOI":"10.1016\/j.mtcomm.2022.104747","article-title":"A review on biogenic green synthesis of ZnO nanoparticles by plant biomass and their applications","volume":"33","author":"Zeghoud","year":"2022","journal-title":"Mater. Today Commun."},{"key":"B198","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1002\/jobm.202200513","article-title":"Effect of biosynthesized selenium nanoparticles using nepeta extract against multidrug\u2010resistant Pseudomonas aeruginosa and Acinetobacter baumannii","volume":"63","author":"Zeraatkar","year":"2022","journal-title":"J. Basic Microbiol."},{"key":"B199","doi-asserted-by":"publisher","first-page":"110630","DOI":"10.1016\/j.envres.2020.110630","article-title":"Antibacterial properties and mechanism of selenium nanoparticles synthesized by providencia sp. DCX","volume":"194","author":"Zhang","year":"2021","journal-title":"Environ. Res."},{"key":"B200","doi-asserted-by":"publisher","first-page":"4541","DOI":"10.1039\/D0CS01030H","article-title":"Stimuli-responsive metal\u2013organic framework nanoparticles for controlled drug delivery and medical applications","volume":"50","author":"Zhou","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"B201","doi-asserted-by":"publisher","first-page":"430","DOI":"10.3390\/bios12100430","article-title":"Biosensors and drug delivery in oncotheranostics using inorganic synthetic and biogenic magnetic nanoparticles","volume":"12","author":"Zimina","year":"2022","journal-title":"Biosens. (Basel)"}],"container-title":["Frontiers in Bioengineering and Biotechnology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fbioe.2026.1752199\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T06:36:34Z","timestamp":1774506994000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fbioe.2026.1752199\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,26]]},"references-count":199,"alternative-id":["10.3389\/fbioe.2026.1752199"],"URL":"https:\/\/doi.org\/10.3389\/fbioe.2026.1752199","relation":{},"ISSN":["2296-4185"],"issn-type":[{"value":"2296-4185","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,26]]},"article-number":"1752199"}}