{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T06:27:48Z","timestamp":1787120868706,"version":"build-2736575974"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Developmental dysplasia of the hip alters acetabular morphology and load transfer, but classification-related changes in local stress distribution remain incompletely understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A Crowe type I finite element model was directly reconstructed from one patient\u2019s pelvic computed tomography data. Crowe type II and III models were subsequently generated from the same anatomical baseline as standardized, classification-consistent virtual morphologies rather than independent patient-specific cases. This single-baseline, internally controlled design was used to reduce inter-individual anatomical variability and evaluate morphology-related changes in stress distribution and load-transfer pathways. A simplified 600\u00a0N axial load was applied to compare peak von Mises stress and stress distribution in the acetabular-side pelvic bone, acetabular\/pseudoacetabular cartilage, proximal femur, and femoral head cartilage. To assess the influence of the simplified loading assumption, an additional loading-sensitivity analysis was performed using a 1,888\u00a0N resultant force inclined medially by 16\u00b0 from the global vertical direction in the frontal plane.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Peak stress within the acetabular-side pelvic bone region increased from Crowe type I to III (2.41, 5.79, and 6.71\u00a0MPa, respectively), whereas acetabular\/pseudoacetabular cartilage stress peaked in type II (3.54\u00a0MPa). Femoral head cartilage stress increased progressively from 1.23\u00a0MPa in type I to 2.08\u00a0MPa in type II and 3.42\u00a0MPa in type III. High-stress regions migrated from the superior true acetabulum to the true acetabulum\u2013pseudoacetabulum transition region and then to the localized pseudoacetabular load-bearing region. Under the alternative loading scenario, the principal classification-dependent stress relationships and pelvic-side stress-location migration pattern were maintained. Material-property sensitivity analyses produced peak-stress changes of no more than 2.46% and similarly preserved these patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Across the standardized Crowe type I\u2013III virtual models, increasing classification severity was associated not only with changes in stress magnitude but also with spatial migration of the principal load-bearing regions. These findings provide an internally controlled biomechanical reference for understanding classification-related load-transfer patterns but should not be interpreted as patient-specific predictions or population-level stress thresholds. Independent patient datasets are required to validate these hypothesis-generating observations before clinical application.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fbioe.2026.1899897","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T05:47:18Z","timestamp":1787118438000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Single-baseline virtual progression modeling of Crowe type I\u2013III developmental dysplasia of the hip: a finite element study of stress-location migration"],"prefix":"10.3389","volume":"14","author":[{"given":"Heng","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University","place":["Bengbu, Anhui, China"]},{"name":"The First School of Clinical Medicine, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuanhao","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyu","family":"Long","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixuan","family":"Li","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenze","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First School of Clinical Medicine, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University","place":["Bengbu, Anhui, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1177\/11207000231212403","article-title":"Providing a computationally derived, mechanically optimised target correction during preoperative planning can improve joint contact mechanics of hip dysplasia treated with periacetabular osteotomy","volume":"34","author":"Aitken","year":"2024","journal-title":"Hip Int."},{"key":"B2","doi-asserted-by":"publisher","first-page":"051008","DOI":"10.1115\/1.2953472","article-title":"Validation of finite element predictions of cartilage contact pressure in the human hip joint","volume":"130","author":"Anderson","year":"2008","journal-title":"J. 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