{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T04:56:03Z","timestamp":1790916963196,"version":"4.1.0"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Clin. Diabetes Healthc."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Type 1 Diabetes (T1D) is a chronic and demanding condition. In recent years, the development of immunomodulatory therapies has increased interest in early detection programs, which may delay disease onset and enable psychological preparedness. However, such programs also introduce new psychosocial considerations. This study explores how first-degree relatives of individuals with T1D perceive and experience participation in an early detection program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Semi-structured interviews were conducted with 28 adults aged 18\u201342 years participating in a Danish early detection program for T1D (DiaUnion). Data were analyzed using reflexive thematic analysis to explore patterns related to risk perception and meaning-making.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The analysis identified three main themes. First, narrative understanding of diabetes based on parental experience illustrates how perceptions of risk are shaped by family narratives and lived experiences. Second, general understanding of diabetes shows that perceptions are often informed by personal beliefs rather than biomedical knowledge. Third, interpretation of the screening result demonstrates that results are frequently downplayed and assigned limited personal significance. Across themes, participants actively constructed meaning around their risk through coping strategies such as normalization, reframing, and emphasizing controllability, which contributed to a generally low perceived risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Risk perception among first-degree relatives is shaped by pre-existing personal and familial narratives, which influence how screening results are interpreted. Early detection programs should therefore move beyond standardized communication and adopt more individualized approaches that account for participants\u2019 existing frameworks of understanding and coping.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcdhc.2026.1925120","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T04:37:18Z","timestamp":1790915838000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["\u201cThis is going to be a nice-to-know, not a need-to-know\u201d: absence of concern \u2013 a qualitative study of risk perception in early detection of type 1 diabetes"],"prefix":"10.3389","volume":"7","author":[{"given":"Emilia Bjergskov","family":"Pedersen","sequence":"first","affiliation":[{"name":"Department of Prevention, Health Promotion & Community Care, Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen","place":["Herlev, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pernille Bech","family":"Flarup","sequence":"additional","affiliation":[{"name":"Department of Prevention, Health Promotion & Community Care, Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen","place":["Herlev, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise Norman","family":"Jespersen","sequence":"additional","affiliation":[{"name":"Department of Prevention, Health Promotion & Community Care, Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen","place":["Herlev, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Due-Christensen","sequence":"additional","affiliation":[{"name":"Department of Prevention, Health Promotion & Community Care, Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen","place":["Herlev, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie Christine","family":"Antvorskov","sequence":"additional","affiliation":[{"name":"Translational Type 1 Diabetes Research, Department of Clinical Research, Steno Diabetes Center Copenhagen","place":["Herlev, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flemming","family":"Pociot","sequence":"additional","affiliation":[{"name":"Translational Type 1 Diabetes Research, Department of Clinical Research, Steno Diabetes Center Copenhagen","place":["Herlev, Denmark"]},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Grabowski","sequence":"additional","affiliation":[{"name":"Department of Prevention, Health Promotion & Community Care, Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen","place":["Herlev, Denmark"]},{"name":"Department of Public Health, University of Southern Denmark","place":["Odense, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,10,2]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/dom.16501","article-title":"The changing epidemiology of type 1 diabetes: A global perspective","volume":"27","author":"Bell","year":"2025","journal-title":"Diabetes Obes Metab"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.2337\/dci21-0043","article-title":"The management of type 1 diabetes in adults. 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