{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T11:15:07Z","timestamp":1789902907263,"version":"4.0.1"},"reference-count":335,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell Dev. Biol."],"DOI":"10.3389\/fcell.2017.00052","type":"journal-article","created":{"date-parts":[[2017,5,12]],"date-time":"2017-05-12T03:51:56Z","timestamp":1494561116000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":44,"title":["Neural Stem Cell Plasticity: Advantages in Therapy for the Injured Central Nervous System"],"prefix":"10.3389","volume":"5","author":[{"given":"Linda","family":"Ottoboni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Merlini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianvito","family":"Martino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,5,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1159\/000262529","article-title":"Role of the growth hormone\/insulin-like growth factor 1 axis in neurogenesis","volume":"17","author":"Aberg","year":"2010","journal-title":"Endocr. Dev."},{"key":"B2","doi-asserted-by":"publisher","first-page":"4408","DOI":"10.1523\/JNEUROSCI.6003-08.2009","article-title":"Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain","volume":"29","author":"Ahlenius","year":"2009","journal-title":"J. Neurosci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1038\/nature03994","article-title":"In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog","volume":"437","author":"Ahn","year":"2005","journal-title":"Nature"},{"key":"B4","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1126\/science.135.3509.1127","article-title":"Are new neurons formed in the brains of adult mammals?","volume":"135","author":"Altman","year":"1962","journal-title":"Science"},{"key":"B5","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/cne.901240303","article-title":"Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats","volume":"124","author":"Altman","year":"1965","journal-title":"J. Comp. Neurol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1242\/dev.122796","article-title":"A comparative view of regenerative neurogenesis in vertebrates","volume":"143","author":"Alunni","year":"2016","journal-title":"Development"},{"key":"B7","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/S0896-6273(04)00111-4","article-title":"For the long run: maintaining germinal niches in the adult brain","volume":"41","author":"Alvarez-Buylla","year":"2004","journal-title":"Neuron"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0079-6123(00)27002-7","article-title":"The subventricular zone: source of neuronal precursors for brain repair","volume":"127","author":"Alvarez-Buylla","year":"2000","journal-title":"Prog. Brain Res."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1007\/s00018-013-1509-8","article-title":"Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration","volume":"71","author":"Andersen","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1093\/brain\/awr094","article-title":"Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain","volume":"134","author":"Andres","year":"2011","journal-title":"Brain"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e9414","DOI":"10.1371\/journal.pone.0009414","article-title":"Angiogenic factors stimulate growth of adult neural stem cells","volume":"5","author":"Androutsellis-Theotokis","year":"2010","journal-title":"PLoS ONE"},{"key":"B12","doi-asserted-by":"publisher","first-page":"8499","DOI":"10.1038\/srep08499","article-title":"Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner","volume":"5","author":"Arulmoli","year":"2015","journal-title":"Sci. Rep."},{"key":"B13","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1038\/nm747","article-title":"Neuronal replacement from endogenous precursors in the adult brain after stroke","volume":"8","author":"Arvidsson","year":"2002","journal-title":"Nat. Med."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1038\/nn.3212","article-title":"Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling","volume":"15","author":"Ashton","year":"2012","journal-title":"Nat. Neurosci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"2030","DOI":"10.1016\/j.neurobiolaging.2009.11.022","article-title":"Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats","volume":"32","author":"Bachstetter","year":"2011","journal-title":"Neurobiol. Aging"},{"key":"B16","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1093\/brain\/awp174","article-title":"Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms","volume":"132","author":"Bacigaluppi","year":"2009","journal-title":"Brain"},{"key":"B17","doi-asserted-by":"publisher","first-page":"10529","DOI":"10.1523\/JNEUROSCI.1643-16.2016","article-title":"Neural stem cell transplantation induces stroke recovery by upregulating glutamate transporter GLT-1 in astrocytes","volume":"36","author":"Bacigaluppi","year":"2016","journal-title":"J. Neurosci."},{"key":"B18","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1111\/j.1474-9728.2004.00128.x","article-title":"Accumulation of mutations and somatic selection in aging neural stem\/progenitor cells","volume":"3","author":"Bailey","year":"2004","journal-title":"Aging Cell"},{"key":"B19","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1089\/scd.2006.15.407","article-title":"Identification of astrocyte-expressed factors that modulate neural stem\/progenitor cell differentiation","volume":"15","author":"Barkho","year":"2006","journal-title":"Stem Cells Dev."},{"key":"B20","doi-asserted-by":"publisher","first-page":"501","DOI":"10.3389\/fncel.2015.00501","article-title":"Exosomes as novel regulators of adult neurogenic niches","volume":"9","author":"Batiz","year":"2015","journal-title":"Front. Cell. Neurosci."},{"key":"B21","doi-asserted-by":"publisher","first-page":"3182","DOI":"10.1523\/JNEUROSCI.0156-06.2006","article-title":"Chemokines regulate the migration of neural progenitors to sites of neuroinflammation","volume":"26","author":"Belmadani","year":"2006","journal-title":"J. Neurosci."},{"key":"B22","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.jns.2007.05.007","article-title":"Immunomodulation by neural stem cells","volume":"265","author":"Ben-Hur","year":"2008","journal-title":"J. Neurol. Sci."},{"key":"B23","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1016\/S1044-7431(03)00218-5","article-title":"Effects of proinflammatory cytokines on the growth, fate, and motility of multipotential neural precursor cells","volume":"24","author":"Ben-Hur","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"B24","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/nature12069","article-title":"Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4","volume":"497","author":"Benner","year":"2013","journal-title":"Nature"},{"key":"B25","doi-asserted-by":"publisher","first-page":"2539","DOI":"10.1002\/stem.1749","article-title":"Nitric oxide-induced neuronal to glial lineage fate-change depends on NRSF\/REST function in neural progenitor cells","volume":"32","author":"Bergsland","year":"2014","journal-title":"Stem Cells"},{"key":"B26","doi-asserted-by":"publisher","first-page":"11464","DOI":"10.1073\/pnas.172403999","article-title":"Newly generated neurons in the amygdala and adjoining cortex of adult primates","volume":"99","author":"Bernier","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B27","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.devcel.2015.01.010","article-title":"It takes a village: constructing the neurogenic niche","volume":"32","author":"Bjornsson","year":"2015","journal-title":"Dev. Cell"},{"key":"B28","doi-asserted-by":"publisher","first-page":"5503","DOI":"10.1242\/dev.02166","article-title":"LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells","volume":"132","author":"Bonaguidi","year":"2005","journal-title":"Development"},{"key":"B29","doi-asserted-by":"publisher","first-page":"9194","DOI":"10.1523\/JNEUROSCI.3314-07.2008","article-title":"Noggin expands neural stem cells in the adult hippocampus","volume":"28","author":"Bonaguidi","year":"2008","journal-title":"J. Neurosci."},{"key":"B30","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1128\/MCB.19.3.1950","article-title":"Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity","volume":"19","author":"Bonizzi","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/S0140-6736(16)31259-4","article-title":"Age of PISCES: stem-cell clinical trials in stroke","volume":"388","author":"Borlongan","year":"2016","journal-title":"Lancet"},{"key":"B32","doi-asserted-by":"publisher","first-page":"894","DOI":"10.4103\/1673-5374.184454","article-title":"Graphene platform for neural regenerative medicine","volume":"11","author":"Bouzid","year":"2016","journal-title":"Neural Regen Res."},{"key":"B33","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1186\/s12967-014-0296-9","article-title":"Graphene based scaffolds effects on stem cells commitment","volume":"12","author":"Bressan","year":"2014","journal-title":"J. Transl. Med."},{"key":"B34","doi-asserted-by":"publisher","first-page":"13127","DOI":"10.1073\/pnas.0804558105","article-title":"Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling","volume":"105","author":"Breunig","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B35","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0306-4522(98)00693-9","article-title":"Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats","volume":"89","author":"Brezun","year":"1999","journal-title":"Neuroscience"},{"key":"B36","doi-asserted-by":"publisher","first-page":"3581","DOI":"10.1073\/pnas.0709002105","article-title":"Origin and progeny of reactive gliosis: a source of multipotent cells in the injured brain","volume":"105","author":"Buffo","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B37","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.mcn.2005.10.006","article-title":"Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem\/progenitor cells","volume":"31","author":"Butovsky","year":"2006","journal-title":"Mol. Cell. Neurosci."},{"key":"B38","doi-asserted-by":"publisher","first-page":"3320","DOI":"10.1093\/brain\/aws194","article-title":"Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity","volume":"135","author":"Butti","year":"2012","journal-title":"Brain"},{"key":"B39","doi-asserted-by":"publisher","first-page":"92","DOI":"10.3389\/fnins.2014.00092","article-title":"Neurogenic and non-neurogenic functions of endogenous neural stem cells","volume":"8","author":"Butti","year":"2014","journal-title":"Front. Neurosci."},{"key":"B40","doi-asserted-by":"publisher","first-page":"4607","DOI":"10.1021\/pr500609e","article-title":"Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis","volume":"13","author":"Bystrom","year":"2014","journal-title":"J. Proteome Res."},{"key":"B41","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1073\/pnas.95.6.3209","article-title":"Proliferation and phenotype regulation in the subventricular zone during experimental allergic encephalomyelitis: in vivo evidence of a role for nerve growth factor","volume":"95","author":"Calza","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B42","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1038\/ng1395","article-title":"VEGF links hippocampal activity with neurogenesis, learning and memory","volume":"36","author":"Cao","year":"2004","journal-title":"Nat. Genet."},{"key":"B43","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.immuni.2011.06.011","article-title":"Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease","volume":"35","author":"Cao","year":"2011","journal-title":"Immunity"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1002\/stem.1408","article-title":"Astrocytic adenosine 5'-triphosphate release regulates the proliferation of neural stem cells in the adult hippocampus","volume":"31","author":"Cao","year":"2013","journal-title":"Stem Cells"},{"key":"B45","doi-asserted-by":"publisher","first-page":"11068","DOI":"10.1073\/pnas.1006375107","article-title":"Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis","volume":"107","author":"Carbajal","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B46","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/nn.2268","article-title":"Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke","volume":"12","author":"Carlen","year":"2009","journal-title":"Nat. Neurosci."},{"key":"B47","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.neuron.2009.08.038","article-title":"Immune influence on adult neural stem cell regulation and function","volume":"64","author":"Carpentier","year":"2009","journal-title":"Neuron"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1002\/stem.444","article-title":"Nitric oxide stimulates the proliferation of neural stem cells bypassing the epidermal growth factor receptor","volume":"28","author":"Carreira","year":"2010","journal-title":"Stem Cells"},{"key":"B49","doi-asserted-by":"publisher","first-page":"343","DOI":"10.3389\/fncel.2014.00343","article-title":"Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling","volume":"8","author":"Carreira","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"B50","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1111\/acel.12365","article-title":"Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging","volume":"14","author":"Chaker","year":"2015","journal-title":"Aging Cell"},{"key":"B51","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1002\/wdev.248","article-title":"A mosaic world: puzzles revealed by adult neural stem cell heterogeneity","volume":"5","author":"Chaker","year":"2016","journal-title":"Wiley Interdiscip. Rev. Dev. Biol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1038\/nrneurol.2012.98","article-title":"The immunology of acute stroke","volume":"8","author":"Chamorro","year":"2012","journal-title":"Nat. Rev. Neurol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"2366","DOI":"10.1093\/brain\/awn157","article-title":"Neurogenesis in the chronic lesions of multiple sclerosis","volume":"131","author":"Chang","year":"2008","journal-title":"Brain"},{"key":"B54","doi-asserted-by":"publisher","first-page":"2366","DOI":"10.1523\/JNEUROSCI.5071-04.2005","article-title":"Endothelial nitric oxide synthase regulates brain-derived neurotrophic factor expression and neurogenesis after stroke in mice","volume":"25","author":"Chen","year":"2005","journal-title":"J. Neurosci."},{"key":"B55","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.bbi.2013.01.083","article-title":"Differential roles of TNFR1 and TNFR2 signaling in adult hippocampal neurogenesis","volume":"30","author":"Chen","year":"2013","journal-title":"Brain Behav. Immun."},{"key":"B56","doi-asserted-by":"publisher","first-page":"2019","DOI":"10.1159\/000374009","article-title":"Sonic hedgehog signaling mediates resveratrol to increase proliferation of neural stem cells after oxygen-glucose deprivation\/reoxygenation injury in vitro","volume":"35","author":"Cheng","year":"2015","journal-title":"Cell. Physiol. Biochem."},{"key":"B57","doi-asserted-by":"publisher","first-page":"29029","DOI":"10.1038\/srep29029","article-title":"Human neural stem cell-induced endothelial morphogenesis requires autocrine\/paracrine and juxtacrine signaling","volume":"6","author":"Chou","year":"2016","journal-title":"Sci. Rep."},{"key":"B58","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1002\/glia.22689","article-title":"Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells","volume":"62","author":"Chucair-Elliott","year":"2014","journal-title":"Glia"},{"key":"B59","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1016\/j.neuron.2014.02.039","article-title":"Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche","volume":"82","author":"Codega","year":"2014","journal-title":"Neuron"},{"key":"B60","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1002\/pmic.201400360","article-title":"A targeted secretome profiling by multiplexed immunoassay revealed that secreted chemokine ligand 2 (MCP-1\/CCL2) affects neural differentiation in mesencephalic neural progenitor cells","volume":"15","author":"Colucci-D'Amato","year":"2015","journal-title":"Proteomics"},{"key":"B61","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1038\/nature03260","article-title":"Rejuvenation of aged progenitor cells by exposure to a young systemic environment","volume":"433","author":"Conboy","year":"2005","journal-title":"Nature"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2016.11.007","article-title":"Development and aging of a brain neural stem cell niche","author":"Conover","year":"2016","journal-title":"Exp. Gerontol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1038\/nature04117","article-title":"Vertebrate smoothened functions at the primary cilium","volume":"437","author":"Corbit","year":"2005","journal-title":"Nature"},{"key":"B64","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/j.molcel.2014.08.020","article-title":"Extracellular vesicles from neural stem cells transfer IFN-gamma via Ifngr1 to activate Stat1 signaling in target cells","volume":"56","author":"Cossetti","year":"2014","journal-title":"Mol. Cell"},{"key":"B65","doi-asserted-by":"publisher","first-page":"6889","DOI":"10.4049\/jimmunol.0802907","article-title":"TLR activation induces TNF-alpha production from adult neural stem\/progenitor cells","volume":"182","author":"Covacu","year":"2009","journal-title":"J. Immunol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"919","DOI":"10.3727\/096368910X494623","article-title":"Effects of MRI contrast agents on the stem cell phenotype","volume":"19","author":"Crabbe","year":"2010","journal-title":"Cell Transplant."},{"key":"B67","doi-asserted-by":"publisher","first-page":"S2211","DOI":"10.1016\/j.celrep.2016.03.069","article-title":"Developmental origin of oligodendrocyte lineage cells determines response to demyelination and susceptibility to age-associated functional decline","volume":"13","author":"Crawford","year":"2016","journal-title":"Cell Rep."},{"key":"B68","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/s11481-006-9021-7","article-title":"Debate: \u201cIs increasing neuroinflammation beneficial for neural repair?\u201d","volume":"1","author":"Crutcher","year":"2006","journal-title":"J. Neuroimmune Pharmacol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1002\/jnr.21836","article-title":"Nitric oxide donor up-regulation of SDF1\/CXCR4 and Ang1\/Tie2 promotes neuroblast cell migration after stroke","volume":"87","author":"Cui","year":"2009","journal-title":"J. Neurosci. Res."},{"key":"B70","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1161\/01.STR.0000173151.36031.be","article-title":"Stroke-induced neurogenesis in aged brain","volume":"36","author":"Darsalia","year":"2005","journal-title":"Stroke"},{"key":"B71","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1111\/j.1460-9568.2007.05702.x","article-title":"Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke-damaged rat striatum","volume":"26","author":"Darsalia","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"B72","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1002\/ana.24006","article-title":"Neurological deficits caused by tissue hypoxia in neuroinflammatory disease","volume":"74","author":"Davies","year":"2013","journal-title":"Ann. Neurol."},{"key":"B73","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1097\/WCO.0b013e328352ec45","article-title":"Neural stem cell transplantation in central nervous system disorders: from cell replacement to neuroprotection","volume":"25","author":"De Feo","year":"2012","journal-title":"Curr. Opin. Neurol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"2831","DOI":"10.1007\/s00018-011-0723-5","article-title":"Hypoxia in the regulation of neural stem cells","volume":"68","author":"De Filippis","year":"2011","journal-title":"Cell. Mol. Life Sci."},{"key":"B75","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.neuron.2014.06.015","article-title":"Endothelial NT-3 delivered by vasculature and CSF promotes quiescence of subependymal neural stem cells through nitric oxide induction","volume":"83","author":"Delgado","year":"2014","journal-title":"Neuron"},{"key":"B76","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.neuron.2014.10.033","article-title":"Tgf\u03b2 signaling regulates temporal neurogenesis and potency of neural stem cells in the CNS","volume":"84","author":"Dias","year":"2014","journal-title":"Neuron"},{"key":"B77","doi-asserted-by":"publisher","first-page":"2550","DOI":"10.1074\/mcp.M114.041533","article-title":"Label-free quantitative proteomics of mouse cerebrospinal fluid detects \u03b2-site APP cleaving enzyme (BACE1) protease substrates in vivo","volume":"14","author":"Dislich","year":"2015","journal-title":"Mol. Cell. Proteomics"},{"key":"B78","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0092-8674(00)80783-7","article-title":"Subventricular zone astrocytes are neural stem cells in the adult mammalian brain","volume":"97","author":"Doetsch","year":"1999","journal-title":"Cell"},{"key":"B79","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1186\/s12974-016-0667-7","article-title":"Metabolic determinants of the immune modulatory function of neural stem cells","volume":"13","author":"Drago","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"B80","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1016\/j.biochi.2013.06.020","article-title":"The stem cell secretome and its role in brain repair","volume":"95","author":"Drago","year":"2013","journal-title":"Biochimie"},{"key":"B81","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.cmet.2015.05.010","article-title":"GDF11 increases with age and inhibits skeletal muscle regeneration","volume":"22","author":"Egerman","year":"2015","journal-title":"Cell Metab."},{"key":"B82","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1016\/j.mcn.2003.08.009","article-title":"Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis","volume":"24","author":"Einstein","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"B83","doi-asserted-by":"publisher","first-page":"13632","DOI":"10.1073\/pnas.2234031100","article-title":"Inflammation is detrimental for neurogenesis in adult brain","volume":"100","author":"Ekdahl","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B84","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1111\/j.1365-2990.2011.01224.x","article-title":"Increased neural progenitors in individuals with cerebral small vessel disease","volume":"38","author":"Ekonomou","year":"2012","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"B85","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/S0014-4886(03)00129-8","article-title":"Endogenous and exogenous ciliary neurotrophic factor enhances forebrain neurogenesis in adult mice","volume":"183","author":"Emsley","year":"2003","journal-title":"Exp. Neurol."},{"key":"B86","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1602\/neurorx.1.4.452","article-title":"The repair of complex neuronal circuitry by transplanted and endogenous precursors","volume":"1","author":"Emsley","year":"2004","journal-title":"NeuroRx"},{"key":"B87","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1016\/j.cell.2014.01.044","article-title":"Neurogenesis in the striatum of the adult human brain","volume":"156","author":"Ernst","year":"2014","journal-title":"Cell"},{"key":"B88","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.neuron.2012.12.011","article-title":"Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo","volume":"77","author":"Espuny-Camacho","year":"2013","journal-title":"Neuron"},{"key":"B89","doi-asserted-by":"publisher","first-page":"2435","DOI":"10.1016\/j.bbagen.2012.09.002","article-title":"Signaling mechanisms regulating adult neural stem cells and neurogenesis","volume":"1830","author":"Faigle","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"B90","doi-asserted-by":"publisher","first-page":"e29597","DOI":"10.1371\/journal.pone.0029597","article-title":"Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons","volume":"7","author":"Falk","year":"2012","journal-title":"PLoS ONE"},{"key":"B91","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/S0301-0082(00)00068-X","article-title":"Cerebral microvascular pathology in aging and Alzheimer's disease","volume":"64","author":"Farkas","year":"2001","journal-title":"Prog. Neurobiol."},{"key":"B92","doi-asserted-by":"publisher","first-page":"177","DOI":"10.4021\/jnr70w","article-title":"Severe hypoxia: consequences to neural stem cells and neurons","volume":"1","author":"Felfly","year":"2011","journal-title":"J. Neurol. Res."},{"key":"B93","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.stem.2012.10.002","article-title":"Metabolic plasticity in stem cell homeostasis and differentiation","volume":"11","author":"Folmes","year":"2012","journal-title":"Cell Stem Cell"},{"key":"B94","doi-asserted-by":"publisher","first-page":"19620","DOI":"10.1523\/JNEUROSCI.3238-13.2013","article-title":"The indirect role of fibroblast growth factor-8 in defining neurogenic niches of the olfactory\/GnRH systems","volume":"33","author":"Forni","year":"2013","journal-title":"J. Neurosci."},{"key":"B95","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1093\/gerona\/glu057","article-title":"Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases","volume":"69","author":"Franceschi","year":"2014","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"B96","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1038\/nrn2480","article-title":"Remyelination in the CNS: from biology to therapy","volume":"9","author":"Franklin","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"B97","doi-asserted-by":"publisher","first-page":"5041","DOI":"10.1007\/s12035-015-9428-3","article-title":"Inflammation promotes a conversion of astrocytes into neural progenitor cells via NF-\u03baB activation","volume":"53","author":"Gabel","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"B98","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1242\/jcs.065912","article-title":"LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche","volume":"123","author":"Gajera","year":"2010","journal-title":"J. Cell Sci."},{"key":"B99","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/j.stem.2013.10.002","article-title":"Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway","volume":"13","author":"Gallagher","year":"2013","journal-title":"Cell Stem Cell"},{"key":"B100","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.tibtech.2016.01.006","article-title":"Graphene in regenerative medicine: focus on stem cells and neuronal differentiation","volume":"34","author":"Gardin","year":"2016","journal-title":"Trends Biotechnol."},{"key":"B101","doi-asserted-by":"publisher","first-page":"2506","DOI":"10.1016\/j.bbagen.2014.01.010","article-title":"Extracellular matrix: a dynamic microenvironment for stem cell niche","volume":"1840","author":"Gattazzo","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"B102","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3389\/fnins.2013.00145","article-title":"Adult hippocampal neurogenesis inversely correlates with microglia in conditions of voluntary running and aging","volume":"7","author":"Gebara","year":"2013","journal-title":"Front. Neurosci."},{"key":"B103","doi-asserted-by":"publisher","first-page":"1930","DOI":"10.1073\/pnas.0510410103","article-title":"The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone","volume":"103","author":"Ghashghaei","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B104","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1007\/s12195-015-0401-z","article-title":"Incorporation of retinoic acid releasing microspheres into pluripotent stem cell aggregates for inducing neuronal differentiation","volume":"8","author":"Gomez","year":"2015","journal-title":"Cell. Mol. Bioeng."},{"key":"B105","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1073\/pnas.1016199109","article-title":"Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis","volume":"109","author":"Gomez-Gaviro","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B106","doi-asserted-by":"publisher","first-page":"387","DOI":"10.3389\/fnins.2015.00387","article-title":"Hypothalamic tanycytes-masters and servants of metabolic, neuroendocrine, and neurogenic functions","volume":"9","author":"Goodman","year":"2015","journal-title":"Front. Neurosci."},{"key":"B107","doi-asserted-by":"publisher","first-page":"e1779","DOI":"10.1038\/cddis.2015.151","article-title":"Microglia-derived IL-1\u03b2 triggers p53-mediated cell cycle arrest and apoptosis in neural precursor cells","volume":"6","author":"Guadagno","year":"2015","journal-title":"Cell Death Dis."},{"key":"B108","doi-asserted-by":"publisher","first-page":"e538","DOI":"10.1038\/cddis.2013.59","article-title":"Microglia-derived TNFa induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma","volume":"4","author":"Guadagno","year":"2013","journal-title":"Cell Death Dis."},{"key":"B109","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/j.neuroscience.2009.02.029","article-title":"Transforming growth factor-alpha induces neurogenesis and behavioral improvement in a chronic stroke model","volume":"160","author":"Guerra-Crespo","year":"2009","journal-title":"Neuroscience"},{"key":"B110","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1161\/STROKEAHA.107.500470","article-title":"Intracarotid injection of fluorescence activated cell-sorted CD49d-positive neural stem cells improves targeted cell delivery and behavior after stroke in a mouse stroke model","volume":"39","author":"Guzman","year":"2008","journal-title":"Stroke"},{"key":"B111","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1136\/jnnp-2014-307712","article-title":"Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron","volume":"85","author":"Haider","year":"2014","journal-title":"J. Neurol. Neurosurg. Psychiatr."},{"key":"B112","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1111\/ejn.12207","article-title":"Aging and neurogenesis in the adult forebrain: what we have learned and where we should go from here","volume":"37","author":"Hamilton","year":"2013","journal-title":"Eur. J. Neurosci."},{"key":"B113","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1016\/j.celrep.2014.08.014","article-title":"Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain","volume":"8","author":"Hargus","year":"2014","journal-title":"Cell Rep."},{"key":"B114","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.pharmthera.2013.04.013","article-title":"Microglia during development and aging","volume":"139","author":"Harry","year":"2013","journal-title":"Pharmacol. Ther."},{"key":"B115","doi-asserted-by":"publisher","first-page":"e50444","DOI":"10.1371\/journal.pone.0050444","article-title":"Human neural progenitor cell engraftment increases neurogenesis and microglial recruitment in the brain of rats with stroke","volume":"7","author":"Hassani","year":"2012","journal-title":"PLoS ONE"},{"key":"B116","doi-asserted-by":"publisher","first-page":"771","DOI":"10.2217\/rme.13.71","article-title":"The role of hypoxia in stem cell potency and differentiation","volume":"8","author":"Hawkins","year":"2013","journal-title":"Regen. Med."},{"key":"B117","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.3727\/096368912X657936","article-title":"In vivo and in vitro characterization of the angiogenic effect of CTX0E03 human neural stem cells","volume":"22","author":"Hicks","year":"2013","journal-title":"Cell Transplant."},{"key":"B118","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1186\/scrt519","article-title":"Human neural stem cells rapidly ameliorate symptomatic inflammation in early-stage ischemic-reperfusion cerebral injury","volume":"5","author":"Huang","year":"2014","journal-title":"Stem Cell Res. Ther."},{"key":"B119","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1186\/1471-2164-14-319","article-title":"Characterization of human plasma-derived exosomal RNAs by deep sequencing","volume":"14","author":"Huang","year":"2013","journal-title":"BMC Genomics"},{"key":"B120","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1038\/nature14046","article-title":"Genome-wide characterization of the routes to pluripotency","volume":"516","author":"Hussein","year":"2014","journal-title":"Nature"},{"key":"B121","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1038\/nn.3706","article-title":"The age and genomic integrity of neurons after cortical stroke in humans","volume":"17","author":"Huttner","year":"2014","journal-title":"Nat. Neurosci."},{"key":"B122","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/j.neuron.2011.05.018","article-title":"Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity","volume":"71","author":"Ihrie","year":"2011","journal-title":"Neuron"},{"key":"B123","doi-asserted-by":"publisher","first-page":"18117","DOI":"10.1073\/pnas.0408258102","article-title":"Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1\u03b1\/CXC chemokine receptor 4 pathway","volume":"101","author":"Imitola","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B124","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1038\/jcbfm.2008.47","article-title":"Suppression of stroke-induced progenitor proliferation in adult subventricular zone by tumor necrosis factor receptor 1","volume":"28","author":"Iosif","year":"2008","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"B125","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1002\/jnr.10843","article-title":"Patterns of jagged1, jagged2, delta-like 1 and delta-like 3 expression during late embryonic and postnatal brain development suggest multiple functional roles in progenitors and differentiated cells","volume":"75","author":"Irvin","year":"2004","journal-title":"J. Neurosci. Res."},{"key":"B126","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1038\/nrm3772","article-title":"Metabolic requirements for the maintenance of self-renewing stem cells","volume":"15","author":"Ito","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"B127","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.brainres.2015.04.039","article-title":"Mechanisms of cell-cell interaction in oligodendrogenesis and remyelination after stroke","volume":"1623","author":"Itoh","year":"2015","journal-title":"Brain Res."},{"key":"B128","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1179\/016164108X323771","article-title":"Expression of amyloid precursor protein after rat traumatic brain injury","volume":"31","author":"Itoh","year":"2009","journal-title":"Neurol. Res."},{"key":"B129","volume-title":"Anaerobiosis and Stemness","author":"Ivanovic","year":"2016"},{"key":"B130","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.neuron.2006.06.012","article-title":"PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling","volume":"51","author":"Jackson","year":"2006","journal-title":"Neuron"},{"key":"B131","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3389\/fncel.2017.00093","article-title":"Mechanical strain promots oligodendrocytes differentiation by global changesof gene expression","volume":"11","author":"Jagielska","year":"2017","journal-title":"Front. Cell. Neurosci"},{"key":"B132","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1002\/glia.22906","article-title":"Loss of galectin-3 decreases the number of immune cells in the subventricular zone and restores proliferation in a viral model of multiple sclerosis","volume":"64","author":"James","year":"2016","journal-title":"Glia"},{"key":"B133","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.jstrokecerebrovasdis.2011.09.008","article-title":"Survival and differentiation of transplanted neural stem cells derived from human induced pluripotent stem cells in a rat stroke model","volume":"22","author":"Jensen","year":"2013","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"B134","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1016\/j.neuroimage.2005.06.063","article-title":"Investigation of neural progenitor cell induced angiogenesis after embolic stroke in rat using MRI","volume":"28","author":"Jiang","year":"2005","journal-title":"Neuroimage"},{"key":"B135","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1634\/stemcells.2007-0513","article-title":"Induction of neurogenesis in nonconventional neurogenic regions of the adult central nervous system by niche astrocyte-produced signals","volume":"26","author":"Jiao","year":"2008","journal-title":"Stem Cells"},{"key":"B136","doi-asserted-by":"publisher","first-page":"13198","DOI":"10.1073\/pnas.0603512103","article-title":"Evidence for stroke-induced neurogenesis in the human brain","volume":"103","author":"Jin","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B137","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.brainres.2010.12.037","article-title":"Effect of human neural precursor cell transplantation on endogenous neurogenesis after focal cerebral ischemia in the rat","volume":"1374","author":"Jin","year":"2011","journal-title":"Brain Res."},{"key":"B138","doi-asserted-by":"publisher","first-page":"11946","DOI":"10.1073\/pnas.182296499","article-title":"Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo","volume":"99","author":"Jin","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B139","unstructured":"Expanding the mind: insulin-like growth factor I and brain development59585962 Joseph D'ErcoleA. YeP. 10.1210\/en.2008-092018687773Endocrinology1492008"},{"key":"B140","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/S0140-6736(16)30513-X","article-title":"Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study","volume":"388","author":"Kalladka","year":"2016","journal-title":"Lancet"},{"key":"B141","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.jchemneu.2008.12.009","article-title":"The cellular composition and morphological organization of the rostral migratory stream in the adult human brain","volume":"37","author":"Kam","year":"2009","journal-title":"J. Chem. Neuroanat."},{"key":"B142","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1039\/c6lc00489j","article-title":"Microfluidic systems for stem cell-based neural tissue engineering","volume":"16","author":"Karimi","year":"2016","journal-title":"Lab Chip"},{"key":"B143","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1126\/science.1260384","article-title":"Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness","volume":"348","author":"Katajisto","year":"2015","journal-title":"Science"},{"key":"B144","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1126\/science.1251141","article-title":"Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors","volume":"344","author":"Katsimpardi","year":"2014","journal-title":"Science"},{"key":"B145","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.expneurol.2013.06.025","article-title":"The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche","volume":"248","author":"Kazanis","year":"2013","journal-title":"Exp. Neurol."},{"key":"B146","doi-asserted-by":"publisher","first-page":"2146","DOI":"10.1634\/stemcells.2007-0082","article-title":"Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor fibroblast growth factor 2 from the extracellular milieu","volume":"25","author":"Kerever","year":"2007","journal-title":"Stem Cells"},{"key":"B147","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.jchemneu.2015.06.001","article-title":"Fractone aging in the subventricular zone of the lateral ventricle","volume":"67","author":"Kerever","year":"2015","journal-title":"J. Chem. Neuroanat."},{"key":"B148","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.brainres.2004.07.093","article-title":"Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro","volume":"1027","author":"Kim","year":"2004","journal-title":"Brain Res."},{"key":"B149","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1002\/jnr.20562","article-title":"Microglia in health and disease","volume":"81","author":"Kim","year":"2005","journal-title":"J. Neurosci. Res."},{"key":"B150","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.neuron.2010.03.019","article-title":"The apical complex couples cell fate and cell survival to cerebral cortical development","volume":"66","author":"Kim","year":"2010","journal-title":"Neuron"},{"key":"B151","doi-asserted-by":"publisher","first-page":"4128","DOI":"10.1073\/pnas.1422448112","article-title":"Adult hippocampal neural stem and progenitor cells regulate the neurogenic niche by secreting VEGF","volume":"112","author":"Kirby","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B152","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1002\/cyto.a.20225","article-title":"Immune surveillance of the human central nervous system (CNS): different migration pathways of immune cells through the blood-brain barrier and blood-cerebrospinal fluid barrier in healthy persons","volume":"69","author":"Kleine","year":"2006","journal-title":"Cytometry A"},{"key":"B153","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1038\/nature11689","article-title":"Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis","volume":"493","author":"Knobloch","year":"2013","journal-title":"Nature"},{"key":"B154","doi-asserted-by":"publisher","first-page":"e8809","DOI":"10.1371\/journal.pone.0008809","article-title":"Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years","volume":"5","author":"Knoth","year":"2010","journal-title":"PLoS ONE"},{"key":"B155","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1002\/stem.306","article-title":"Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum","volume":"28","author":"Kojima","year":"2010","journal-title":"Stem Cells"},{"key":"B156","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1038\/nn.3163","article-title":"Cross-talk between neural stem cells and immune cells: the key to better brain repair?","volume":"15","author":"Kokaia","year":"2012","journal-title":"Nat. Neurosci."},{"key":"B157","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1126\/science.1115360","article-title":"Neurogenesis in the hypothalamus of adult mice: potential role in energy balance","volume":"310","author":"Kokoeva","year":"2005","journal-title":"Science"},{"key":"B158","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.stem.2010.05.019","article-title":"Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1\/CXCR4 signaling","volume":"7","author":"Kokovay","year":"2010","journal-title":"Cell Stem Cell"},{"key":"B159","doi-asserted-by":"publisher","first-page":"2388","DOI":"10.1002\/bit.25636","article-title":"Optimization of surface-immobilized extracellular matrices for the proliferation of neural progenitor cells derived from induced pluripotent stem cells","volume":"112","author":"Komura","year":"2015","journal-title":"Biotechnol. Bioeng."},{"key":"B160","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1093\/brain\/awn096","article-title":"Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis","volume":"131","author":"Kuhlmann","year":"2008","journal-title":"Brain"},{"key":"B161","doi-asserted-by":"publisher","first-page":"9","DOI":"10.4137\/CPath.S40497","article-title":"Interferon gamma: influence on neural stem cell function in neurodegenerative and neuroinflammatory disease","volume":"9","author":"Kulkarni","year":"2016","journal-title":"Clin. Med. Insights Pathol."},{"key":"B162","doi-asserted-by":"publisher","first-page":"12601","DOI":"10.1073\/pnas.1306562110","article-title":"Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix","volume":"110","author":"Kusuma","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B163","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1126\/science.1228773","article-title":"Acute inflammation initiates the regenerative response in the adult zebrafish brain","volume":"338","author":"Kyritsis","year":"2012","journal-title":"Science"},{"key":"B164","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S0022-510X(02)00421-5","article-title":"Hypoxia-like tissue injury as a component of multiple sclerosis lesions","volume":"206","author":"Lassmann","year":"2003","journal-title":"J. Neurol. Sci."},{"key":"B165","doi-asserted-by":"publisher","first-page":"2597","DOI":"10.1038\/ncomms3597","article-title":"iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF","volume":"4","author":"Laterza","year":"2013","journal-title":"Nat. Commun."},{"key":"B166","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.stem.2010.11.028","article-title":"Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K\/Akt-dependant manner","volume":"8","author":"Le Belle","year":"2011","journal-title":"Cell Stem Cell"},{"key":"B167","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1523\/JNEUROSCI.3386-12.2013","article-title":"Ciliary neurotrophic factor receptor regulation of adult forebrain neurogenesis","volume":"33","author":"Lee","year":"2013","journal-title":"J. Neurosci."},{"key":"B168","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1146\/annurev-cellbio-092910-154026","article-title":"Neurogenesis at the brain-cerebrospinal fluid interface","volume":"27","author":"Lehtinen","year":"2011","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"B169","doi-asserted-by":"publisher","first-page":"229","DOI":"10.2217\/rme.11.2","article-title":"Role of mechanical factors in fate decisions of stem cells","volume":"6","author":"Li","year":"2011","journal-title":"Regen. Med."},{"key":"B170","doi-asserted-by":"publisher","first-page":"16713","DOI":"10.1523\/JNEUROSCI.4590-13.2014","article-title":"Hypoxia inducible factor-1a(HIF-1a) is required for neural stem cell maintenance and vascular stability in the adult mouse SVZ","volume":"34","author":"Li","year":"2014","journal-title":"J. Neurosci."},{"key":"B171","doi-asserted-by":"publisher","first-page":"1610","DOI":"10.1002\/glia.21033","article-title":"Focal cerebral ischemia induces a multilineage cytogenic response from adult subventricular zone that is predominantly gliogenic","volume":"58","author":"Li","year":"","journal-title":"Glia"},{"key":"B172","doi-asserted-by":"publisher","first-page":"9038","DOI":"10.1523\/JNEUROSCI.5691-09.2010","article-title":"Endogenous interferon gamma directly regulates neural precursors in the non-inflammatory brain","volume":"30","author":"Li","year":"","journal-title":"J. Neurosci."},{"key":"B173","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.tins.2012.06.003","article-title":"Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair","volume":"35","author":"Li","year":"2012","journal-title":"Trends Neurosci."},{"key":"B174","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"},{"key":"B175","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1038\/nature04108","article-title":"Wnt signalling regulates adult hippocampal neurogenesis","volume":"437","author":"Lie","year":"2005","journal-title":"Nature"},{"key":"B176","doi-asserted-by":"crossref","first-page":"6639","DOI":"10.1523\/JNEUROSCI.22-15-06639.2002","article-title":"The adult substantia nigra contains progenitor cells with neurogenic potential","volume":"22","author":"Lie","year":"2002","journal-title":"J. Neurosci."},{"key":"B177","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/S0896-6273(00)00148-3","article-title":"Noggin antagonizes BMP signaling to create a niche for adult neurogenesis","volume":"28","author":"Lim","year":"2000","journal-title":"Neuron"},{"key":"B178","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.stem.2010.02.017","article-title":"Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation","volume":"6","author":"Liu","year":"2010","journal-title":"Cell Stem Cell"},{"key":"B179","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s11357-011-9214-8","article-title":"Age-related changes in AMP-activated protein kinase after stroke","volume":"34","author":"Liu","year":"2012","journal-title":"Age"},{"key":"B180","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1038\/nn.4211","article-title":"Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation","volume":"19","author":"Liu","year":"2016","journal-title":"Nat. Neurosci."},{"key":"B181","doi-asserted-by":"publisher","first-page":"22680","DOI":"10.1074\/jbc.M109.006551","article-title":"Angiopoietin 2 mediates the differentiation and migration of neural progenitor cells in the subventricular zone after stroke","volume":"284","author":"Liu","year":"2009","journal-title":"J. Biol. Chem."},{"key":"B182","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1038\/nn1522","article-title":"Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors","volume":"8","author":"Liu","year":"2005","journal-title":"Nat. Neurosci."},{"key":"B183","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1177\/1073858408331371","article-title":"Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis","volume":"15","author":"Llorens-Martin","year":"2009","journal-title":"Neuroscientist"},{"key":"B184","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1096\/fj.09-150573","article-title":"Thrombospondin 1\u2014a key astrocyte-derived neurogenic factor","volume":"24","author":"Lu","year":"2010","journal-title":"FASEB J."},{"key":"B185","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1038\/ncb2299","article-title":"Phagocytic activity of neuronal progenitors regulates adult neurogenesis","volume":"13","author":"Lu","year":"2011","journal-title":"Nat. Cell Biol."},{"key":"B186","doi-asserted-by":"publisher","first-page":"2041","DOI":"10.1002\/stem.522","article-title":"Bidirectional regulation of neurogenesis by neuronal nitric oxide synthase derived from neurons and neural stem cells","volume":"28","author":"Luo","year":"2010","journal-title":"Stem Cells"},{"key":"B187","doi-asserted-by":"publisher","first-page":"3804","DOI":"10.1523\/JNEUROSCI.0224-08.2008","article-title":"Subventricular zone-mediated ependyma repair in the adult mammalian brain","volume":"28","author":"Luo","year":"2008","journal-title":"J. Neurosci."},{"key":"B188","doi-asserted-by":"publisher","first-page":"13114","DOI":"10.1523\/JNEUROSCI.4667-06.2006","article-title":"Increased generation of neuronal progenitors after ischemic injury in the aged adult human forebrain","volume":"26","author":"Macas","year":"2006","journal-title":"J. Neurosci."},{"key":"B189","doi-asserted-by":"publisher","first-page":"2110","DOI":"10.1634\/stemcells.2006-0018","article-title":"Increased \u201cvigilance\u201d of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress","volume":"24","author":"Madhavan","year":"2006","journal-title":"Stem Cells"},{"key":"B190","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1126\/science.346.6206.237","article-title":"A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse","volume":"346","author":"Magnusson","year":"2014","journal-title":"Science"},{"key":"B191","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/S1474-4422(14)70256-X","article-title":"Pathological mechanisms in progressive multiple sclerosis","volume":"14","author":"Mahad","year":"2015","journal-title":"Lancet Neurol."},{"key":"B192","doi-asserted-by":"publisher","first-page":"5","DOI":"10.7363\/050215","article-title":"Introduction to embryonic and adult neural stem cells: from the metabolic circuits of the niches to the metabolome","author":"Marcialis","year":"2016","journal-title":"J. Pediatric Neonatal. Individualized Med."},{"key":"B193","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.jacc.2010.05.028","article-title":"Age as a risk factor for stroke in atrial fibrillation patients: implications for thromboprophylaxis","volume":"56","author":"Marinigh","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"key":"B194","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/2045-8118-8-10","article-title":"Transcriptome signature of the adult mouse choroid plexus","volume":"8","author":"Marques","year":"2011","journal-title":"Fluids Barriers CNS"},{"key":"B195","doi-asserted-by":"publisher","first-page":"8466","DOI":"10.1038\/ncomms9466","article-title":"Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug","volume":"6","author":"Marschallinger","year":"2015","journal-title":"Nat. Commun."},{"key":"B196","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1212\/WNL.0b013e3181cbccec","article-title":"Proliferation in the human ipsilateral subventricular zone after ischemic stroke","volume":"74","author":"Marti-Fabregas","year":"2010","journal-title":"Neurology"},{"key":"B197","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/S1474-4422(04)00771-9","article-title":"How the brain repairs itself: new therapeutic strategies in inflammatory and degenerative CNS disorders","volume":"3","author":"Martino","year":"2004","journal-title":"Lancet Neurol."},{"key":"B198","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1038\/nrn1908","article-title":"The therapeutic potential of neural stem cells","volume":"7","author":"Martino","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"key":"B199","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1172\/JCI74419","article-title":"Neurogenesis or non-neurogenesis: that is the question","volume":"124","author":"Martino","year":"2014","journal-title":"J. Clin. Invest."},{"key":"B200","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1152\/physrev.00032.2010","article-title":"Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells","volume":"91","author":"Martino","year":"2011","journal-title":"Physiol. Rev."},{"key":"B201","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.neuroscience.2015.08.055","article-title":"Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis","volume":"307","author":"Meng","year":"2015","journal-title":"Neuroscience"},{"key":"B202","doi-asserted-by":"publisher","first-page":"7907","DOI":"10.1523\/JNEUROSCI.1299-06.2006","article-title":"Origin of oligodendrocytes in the subventricular zone of the adult brain","volume":"26","author":"Menn","year":"2006","journal-title":"J. Neurosci."},{"key":"B203","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1002\/cne.10342","article-title":"Anatomy of the brain neurogenic zones revisited: fractones and the fibroblast\/macrophage network","volume":"451","author":"Mercier","year":"2002","journal-title":"J. Comp. Neurol."},{"key":"B204","doi-asserted-by":"publisher","first-page":"454","DOI":"10.3389\/fnins.2014.00454","article-title":"Activation of endogenous neural stem cells for multiple sclerosis therapy","volume":"8","author":"Michailidou","year":"2014","journal-title":"Front. Neurosci."},{"key":"B205","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3233\/NRE-2004-19107","article-title":"Disability in elderly people with multiple sclerosis: An analysis of baseline data from the Sonya Slifka longitudinal multiple sclerosis study","volume":"19","author":"Minden","year":"2004","journal-title":"NeuroRehabilitation"},{"key":"B206","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.nbd.2012.12.006","article-title":"Grafted human neural stem cells enhance several steps of endogenous neurogenesis and improve behavioral recovery after middle cerebral artery occlusion in rats","volume":"52","author":"Mine","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"B207","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1146\/annurev.neuro.28.051804.101459","article-title":"Adult neurogenesis in the mammalian central nervous system","volume":"28","author":"Ming","year":"2005","journal-title":"Annu. Rev. Neurosci."},{"key":"B208","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.neuron.2011.05.001","article-title":"Adult neurogenesis in the mammalian brain: significant answers and significant questions","volume":"70","author":"Ming","year":"2011","journal-title":"Neuron"},{"key":"B209","doi-asserted-by":"publisher","first-page":"69","DOI":"10.2217\/17460751.2.1.69","article-title":"Endogenous neurogenesis in the human brain following cerebral infarction","volume":"2","author":"Minger","year":"2007","journal-title":"Regen. Med."},{"key":"B210","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1111\/j.1474-9726.2012.00816.x","article-title":"Aging brain microenvironment decreases hippocampal neurogenesis through Wnt-mediated survivin signaling","volume":"11","author":"Miranda","year":"2012","journal-title":"Aging Cell"},{"key":"B211","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1038\/nature05091","article-title":"Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing","volume":"443","author":"Molofsky","year":"2006","journal-title":"Nature"},{"key":"B212","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.1126\/science.1088417","article-title":"Inflammatory blockade restores adult hippocampal neurogenesis","volume":"302","author":"Monje","year":"2003","journal-title":"Science"},{"key":"B213","doi-asserted-by":"publisher","first-page":"3981","DOI":"10.1523\/JNEUROSCI.3617-10.2011","article-title":"Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis","volume":"31","author":"Moriyama","year":"2011","journal-title":"J. Neurosci."},{"key":"B214","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1038\/nn.3233","article-title":"Neural progenitor cells regulate microglia functions and activity","volume":"15","author":"Mosher","year":"2012","journal-title":"Nat. Neurosci."},{"key":"B215","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1038\/nrn1829","article-title":"Gene therapy: can neural stem cells deliver?","volume":"7","author":"Muller","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"key":"B216","doi-asserted-by":"publisher","first-page":"860546","DOI":"10.1155\/2015\/860546","article-title":"Generation of new neurons in dorsal root Ganglia in adult rats after peripheral nerve crush injury","volume":"2015","author":"Muratori","year":"2015","journal-title":"Neural Plast."},{"key":"B217","doi-asserted-by":"publisher","first-page":"2825","DOI":"10.1073\/pnas.0530113100","article-title":"Hypoxic neuronal necrosis: protein synthesis-independent activation of a cell death program","volume":"100","author":"Niquet","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B218","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1038\/nm.3651","article-title":"Stem cell aging: mechanisms, regulators and therapeutic opportunities","volume":"20","author":"Oh","year":"2014","journal-title":"Nat. Med."},{"key":"B219","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1177\/1073858407309545","article-title":"Poststroke neurogenesis: emerging principles of migration and localization of immature neurons","volume":"14","author":"Ohab","year":"2008","journal-title":"Neuroscientist"},{"key":"B220","doi-asserted-by":"publisher","first-page":"13007","DOI":"10.1523\/JNEUROSCI.4323-06.2006","article-title":"A neurovascular niche for neurogenesis after stroke","volume":"26","author":"Ohab","year":"2006","journal-title":"J. Neurosci."},{"key":"B221","doi-asserted-by":"publisher","first-page":"3570","DOI":"10.1096\/fj.11-184697","article-title":"Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis","volume":"25","author":"Okamoto","year":"2011","journal-title":"FASEB J."},{"key":"B222","doi-asserted-by":"publisher","first-page":"8754","DOI":"10.1073\/pnas.0803955106","article-title":"Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF","volume":"106","author":"O'Keeffe","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B223","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1002\/stem.1104","article-title":"Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain","volume":"30","author":"Oki","year":"2012","journal-title":"Stem Cells"},{"key":"B224","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.18632\/oncotarget.6803","article-title":"Caspase inhibition impaired the neural stem\/progenitor cell response after cortical ischemia in mice","volume":"7","author":"Osman","year":"2016","journal-title":"Oncotarget"},{"key":"B225","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.neuron.2011.05.029","article-title":"Ank3-dependent SVZ niche assembly is required for the continued production of new neurons","volume":"71","author":"Paez-Gonzalez","year":"2011","journal-title":"Neuron"},{"key":"B226","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1038\/nn.3734","article-title":"Identification of distinct ChAT+ neurons and activity-dependent control of postnatal SVZ neurogenesis","volume":"17","author":"Paez-Gonzalez","year":"2014","journal-title":"Nat. Neurosci."},{"key":"B227","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1002\/1096-9861(20001002)425:4<479::AID-CNE2>3.0.CO;2-3","article-title":"Vascular niche for adult hippocampal neurogenesis","volume":"425","author":"Palmer","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"B228","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1002\/ana.10393","article-title":"Rat forebrain neurogenesis and striatal neuron replacement after focal stroke","volume":"52","author":"Parent","year":"2002","journal-title":"Ann. Neurol."},{"key":"B229","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1083\/jcb.201010024","article-title":"Mitochondrial DNA mutations in disease and aging","volume":"193","author":"Park","year":"2011","journal-title":"J. Cell Biol."},{"key":"B230","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.brainres.2012.02.043","article-title":"Erythropoietin enhances cell proliferation and survival of human fetal neuronal progenitors in normoxia","volume":"1452","author":"Pavlica","year":"2012","journal-title":"Brain Res."},{"key":"B231","doi-asserted-by":"publisher","first-page":"270","DOI":"10.3389\/fncel.2015.00270","article-title":"IFN gamma regulates proliferation and neuronal differentiation by STAT1 in adult SVZ niche","volume":"9","author":"Pereira","year":"2015","journal-title":"Front. Cell. Neurosci."},{"key":"B232","doi-asserted-by":"publisher","first-page":"4208","DOI":"10.1242\/jcs.127803","article-title":"Interleukin-10 regulates progenitor differentiation and modulates neurogenesis in adult brain","volume":"126","author":"Perez-Asensio","year":"2013","journal-title":"J. Cell Sci."},{"key":"B233","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.expneurol.2008.08.006","article-title":"Retinoic acid and environmental enrichment alter subventricular zone and striatal neurogenesis after stroke","volume":"214","author":"Plane","year":"2008","journal-title":"Exp. Neurol."},{"key":"B234","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1016\/j.neuron.2010.03.009","article-title":"NMDA receptors activated by subventricular zone astrocytic glutamate are critical for neuroblast survival prior to entering a synaptic network","volume":"65","author":"Platel","year":"2010","journal-title":"Neuron"},{"key":"B235","first-page":"173","article-title":"Remodelling the injured CNS through the establishment of atypical ectopic perivascular neural stem cell niches","volume":"148","author":"Pluchino","year":"2010","journal-title":"Arch. Ital. Biol."},{"key":"B236","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1002\/ana.21745","article-title":"Human neural stem cells ameliorate autoimmune encephalomyelitis in non-human primates","volume":"66","author":"Pluchino","year":"2009","journal-title":"Ann. Neurol."},{"key":"B237","doi-asserted-by":"publisher","first-page":"2564","DOI":"10.1093\/brain\/awn198","article-title":"Persistent inflammation alters the function of the endogenous brain stem cell compartment","volume":"131","author":"Pluchino","year":"2008","journal-title":"Brain"},{"key":"B238","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/nature01552","article-title":"Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis","volume":"422","author":"Pluchino","year":"2003","journal-title":"Nature"},{"key":"B239","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1038\/nature03889","article-title":"Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism","volume":"436","author":"Pluchino","year":"2005","journal-title":"Nature"},{"key":"B240","doi-asserted-by":"publisher","first-page":"2587","DOI":"10.3727\/096368912X653228","article-title":"Human induced pluripotent stem cells improve stroke outcome and reduce secondary degeneration in the recipient brain","volume":"21","author":"Polentes","year":"2012","journal-title":"Cell Transplant."},{"key":"B241","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.expneurol.2005.12.011","article-title":"A conditionally immortal clonal stem cell line from human cortical neuroepithelium for the treatment of ischemic stroke","volume":"199","author":"Pollock","year":"2006","journal-title":"Exp. Neurol."},{"key":"B242","doi-asserted-by":"publisher","first-page":"216","DOI":"10.2174\/156720207781387213","article-title":"The response of the aged brain to stroke: too much, too soon?","volume":"4","author":"Popa-Wagner","year":"2007","journal-title":"Curr. Neurovasc. Res."},{"key":"B243","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1002\/glia.23124","article-title":"Inflammatory demyelination induces ependymal modifications concomitant to activation of adult (SVZ) stem cell proliferation","volume":"65","author":"Pourabdolhossein","year":"2017","journal-title":"Glia"},{"key":"B244","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.2741\/218","article-title":"Neural stem cell niches: roles for the hyaluronan-based extracellular matrix","volume":"3","author":"Preston","year":"2011","journal-title":"Front. Biosci."},{"key":"B245","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1038\/nbt.3777","article-title":"Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells","volume":"35","author":"Qi","year":"2017","journal-title":"Nat. Biotechnol."},{"key":"B246","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1002\/cne.20798","article-title":"Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells","volume":"494","author":"Quinones-Hinojosa","year":"2006","journal-title":"J. Comp. Neurol."},{"key":"B247","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/j.ijdevneu.2011.06.003","article-title":"Impaired hypoxic response in senescent mouse brain","volume":"29","author":"Rabie","year":"2011","journal-title":"Int. J. Dev. Neurosci."},{"key":"B248","doi-asserted-by":"publisher","first-page":"5597","DOI":"10.1242\/jcs.114827","article-title":"Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate","volume":"125","author":"Rafalski","year":"2012","journal-title":"J. Cell Sci."},{"key":"B249","doi-asserted-by":"publisher","first-page":"e59252","DOI":"10.1371\/journal.pone.0059252","article-title":"Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling","volume":"8","author":"Reinhardt","year":"2013","journal-title":"PLoS ONE"},{"key":"B250","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/S0306-4522(02)00307-X","article-title":"Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer","volume":"115","author":"Reiss","year":"2002","journal-title":"Neuroscience"},{"key":"B251","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jns.2008.04.027","article-title":"Taking ageing into account in remyelination-based therapies for multiple sclerosis","volume":"274","author":"Rist","year":"2008","journal-title":"J. Neurol. Sci."},{"key":"B252","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.1161\/CIR.0b013e31823ac046","article-title":"Heart disease and stroke statistics\u20132012 update: a report from the American Heart Association","volume":"125","author":"Roger","year":"2012","journal-title":"Circulation"},{"key":"B253","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1126\/science.1139740","article-title":"Patched1 regulates hedgehog signaling at the primary cilium","volume":"317","author":"Rohatgi","year":"2007","journal-title":"Science"},{"key":"B254","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.stem.2011.11.019","article-title":"Rejuvenation of regeneration in the aging central nervous system","volume":"10","author":"Ruckh","year":"2012","journal-title":"Cell Stem Cell"},{"key":"B255","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1152\/physrev.00031.2008","article-title":"Role and therapeutic potential of VEGF in the nervous system","volume":"89","author":"Ruiz de Almodovar","year":"2009","journal-title":"Physiol. Rev."},{"key":"B256","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1038\/nature14957","article-title":"Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination","volume":"526","author":"Samanta","year":"2015","journal-title":"Nature"},{"key":"B257","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1038\/nature02301","article-title":"Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration","volume":"427","author":"Sanai","year":"2004","journal-title":"Nature"},{"key":"B258","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1089\/scd.2016.0268","article-title":"Strategies to enhance implantation and survival of stem cells after their injection in ischemic neural tissue","volume":"26","author":"Sandvig","year":"2017","journal-title":"Stem Cells Dev."},{"key":"B259","doi-asserted-by":"publisher","first-page":"e8575","DOI":"10.1371\/journal.pone.0008575","article-title":"Mild hypoxia enhances proliferation and multipotency of human neural stem cells","volume":"5","author":"Santilli","year":"2010","journal-title":"PLoS ONE"},{"key":"B260","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1212\/WNL.0b013e318230a17d","article-title":"Age and disability accumulation in multiple sclerosis","volume":"77","author":"Scalfari","year":"2011","journal-title":"Neurology"},{"key":"B261","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.stem.2012.11.010","article-title":"Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline","volume":"12","author":"Seib","year":"2013","journal-title":"Cell Stem Cell"},{"key":"B262","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1002\/cne.20288","article-title":"Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus","volume":"478","author":"Seri","year":"2004","journal-title":"J. Comp. Neurol."},{"key":"B263","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1126\/science.1095505","article-title":"Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells","volume":"304","author":"Shen","year":"2004","journal-title":"Science"},{"key":"B264","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.stem.2008.07.026","article-title":"Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions","volume":"3","author":"Shen","year":"2008","journal-title":"Cell Stem Cell"},{"key":"B265","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.5966\/sctm.2015-0270","article-title":"Grafted subventricular zone neural stem cells display robust engraftment and similar differentiation properties and form new neurogenic niches in the young and aged hippocampus","volume":"5","author":"Shetty","year":"2016","journal-title":"Stem Cells Transl. Med."},{"key":"B266","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1002\/glia.20187","article-title":"Stem\/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes","volume":"51","author":"Shetty","year":"2005","journal-title":"Glia"},{"key":"B267","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1101\/lm.76006","article-title":"NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis","volume":"13","author":"Shimazu","year":"2006","journal-title":"Learn. Mem."},{"key":"B268","doi-asserted-by":"publisher","first-page":"2535","DOI":"10.1242\/dev.091777","article-title":"Stem cell metabolism in tissue development and aging","volume":"140","author":"Shyh-Chang","year":"2013","journal-title":"Development"},{"key":"B269","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/j.cell.2009.10.004","article-title":"Retinoic acid from the meninges regulates cortical neuron generation","volume":"139","author":"Siegenthaler","year":"2009","journal-title":"Cell"},{"key":"B270","doi-asserted-by":"publisher","first-page":"240","DOI":"10.3389\/fncel.2014.00240","article-title":"Never-resting microglia: physiological roles in the healthy brain and pathological implications","volume":"8","author":"Sierra","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"B271","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1523\/JNEUROSCI.22-07-02451.2002","article-title":"The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation","volume":"22","author":"Sim","year":"2002","journal-title":"J. Neurosci."},{"key":"B272","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1016\/j.ijdevneu.2005.03.001","article-title":"Total antioxidant capacity is impaired in different structures from aged rat brain","volume":"23","author":"Siqueira","year":"2005","journal-title":"Int. J. Dev. Neurosci."},{"key":"B273","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1038\/nm.3898","article-title":"\u03b22-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis","volume":"21","author":"Smith","year":"2015","journal-title":"Nat. Med."},{"key":"B274","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1161\/CIRCRESAHA.115.307527","article-title":"GDF11 does not rescue aging-related pathological hypertrophy","volume":"117","author":"Smith","year":"2015","journal-title":"Circ. Res."},{"key":"B275","doi-asserted-by":"publisher","first-page":"2160","DOI":"10.1016\/j.bbagen.2012.09.021","article-title":"Death receptors and mitochondria: two prime triggers of neural apoptosis and differentiation","volume":"1830","author":"Sola","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"B276","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1038\/nature11306","article-title":"Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision","volume":"489","author":"Song","year":"2012","journal-title":"Nature"},{"key":"B277","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.arr.2005.02.001","article-title":"Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging","volume":"4","author":"Sonntag","year":"2005","journal-title":"Ageing Res. Rev."},{"key":"B278","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1016\/j.cell.2013.05.002","article-title":"Dynamics of hippocampal neurogenesis in adult humans","volume":"153","author":"Spalding","year":"2013","journal-title":"Cell"},{"key":"B279","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1002\/embj.201386917","article-title":"Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging","volume":"33","author":"Stein","year":"2014","journal-title":"EMBO J."},{"key":"B280","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1093\/brain\/awh217","article-title":"Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination","volume":"127","author":"Stidworthy","year":"2004","journal-title":"Brain"},{"key":"B281","doi-asserted-by":"publisher","first-page":"20","DOI":"10.3389\/fnins.2015.00020","article-title":"Neurogenic niches in the brain: help and hindrance of the barrier systems","volume":"9","author":"Stolp","year":"2015","journal-title":"Front. Neurosci."},{"key":"B282","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.brainresbull.2014.09.005","article-title":"The interaction between microglia and neural stem\/precursor cells","volume":"109","author":"Su","year":"2014","journal-title":"Brain Res. Bull."},{"key":"B283","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1146\/annurev.cellbio.042308.113256","article-title":"Signaling in adult neurogenesis","volume":"25","author":"Suh","year":"2009","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"B284","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/BF03164835","article-title":"Clinical significance of reduced cerebral metabolism in multiple sclerosis: a combined PET and MRI study","volume":"12","author":"Sun","year":"1998","journal-title":"Ann. Nucl. Med."},{"key":"B285","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1016\/j.cell.2007.11.019","article-title":"Induction of pluripotent stem cells from adult human fibroblasts by defined factors","volume":"131","author":"Takahashi","year":"2007","journal-title":"Cell"},{"key":"B286","doi-asserted-by":"publisher","first-page":"547","DOI":"10.3233\/RNN-140404","article-title":"Human induced pluripotent stem cells improve recovery in stroke-injured aged rats","volume":"32","author":"Tatarishvili","year":"2014","journal-title":"Restor. Neurol. Neurosci."},{"key":"B287","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.stem.2008.07.025","article-title":"A specialized vascular niche for adult neural stem cells","volume":"3","author":"Tavazoie","year":"2008","journal-title":"Cell Stem Cell"},{"key":"B288","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1146\/annurev-cellbio-101011-155801","article-title":"The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex","volume":"30","author":"Taverna","year":"2014","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"B289","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1038\/35102174","article-title":"The development of neural stem cells","volume":"414","author":"Temple","year":"2001","journal-title":"Nature"},{"key":"B290","doi-asserted-by":"publisher","first-page":"4722","DOI":"10.1172\/JCI59145","article-title":"Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis","volume":"121","author":"Tepavcevic","year":"2011","journal-title":"J. Clin. Invest."},{"key":"B291","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1038\/nri855","article-title":"Exosomes: composition, biogenesis and function","volume":"2","author":"Thery","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"B292","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1634\/stemcells.2005-0281","article-title":"Persistent production of neurons from adult brain stem cells during recovery after stroke","volume":"24","author":"Thored","year":"2006","journal-title":"Stem Cells"},{"key":"B293","doi-asserted-by":"publisher","first-page":"3032","DOI":"10.1161\/STROKEAHA.107.488445","article-title":"Long-term neuroblast migration along blood vessels in an area with transient angiogenesis and increased vascularization after stroke","volume":"38","author":"Thored","year":"2007","journal-title":"Stroke"},{"key":"B294","doi-asserted-by":"publisher","first-page":"59","DOI":"10.3389\/fncel.2013.00059","article-title":"Genetic control of adult neurogenesis: interplay of differentiation, proliferation and survival modulates new neurons function, and memory circuits","volume":"7","author":"Tirone","year":"2013","journal-title":"Front. Cell. Neurosci."},{"key":"B295","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/S1044-7431(03)00058-7","article-title":"Proliferation of neural and neuronal progenitors after global brain ischemia in young adult macaque monkeys","volume":"23","author":"Tonchev","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"B296","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1093\/brain\/aww347","article-title":"Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli","volume":"40","author":"Tornero","year":"2017","journal-title":"Brain"},{"key":"B297","doi-asserted-by":"publisher","first-page":"3561","DOI":"10.1093\/brain\/awt278","article-title":"Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery","volume":"36","author":"Tornero","year":"2013","journal-title":"Brain 1"},{"key":"B298","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/S1474-4422(09)70043-2","article-title":"Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis","volume":"8","author":"Trapp","year":"2009","journal-title":"Lancet Neurol."},{"key":"B299","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.expneurol.2004.08.034","article-title":"Presence of nerve growth factor and TrkA expression in the SVZ of EAE rats: evidence for a possible functional significance","volume":"191","author":"Triaca","year":"2005","journal-title":"Exp. Neurol."},{"key":"B300","doi-asserted-by":"crossref","first-page":"7850","DOI":"10.1523\/JNEUROSCI.17-20-07850.1997","article-title":"Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma","volume":"17","author":"Tropepe","year":"1997","journal-title":"J. Neurosci."},{"key":"B301","doi-asserted-by":"publisher","first-page":"14522","DOI":"10.1523\/JNEUROSCI.3673-08.2008","article-title":"Enhanced adult neurogenesis and angiogenesis and altered affective behaviors in mice overexpressing vascular endothelial growth factor 120","volume":"28","author":"Udo","year":"2008","journal-title":"J. Neurosci."},{"key":"B302","doi-asserted-by":"crossref","first-page":"11732","DOI":"10.1523\/JNEUROSCI.23-37-11732.2003","article-title":"A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus","volume":"23","author":"Ueki","year":"2003","journal-title":"J. Neurosci."},{"key":"B303","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1006\/mcne.2002.1208","article-title":"Soluble interleukin-6 (IL-6) receptor\/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells","volume":"21","author":"Valerio","year":"2002","journal-title":"Mol. Cell. Neurosci."},{"key":"B304","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1523\/JNEUROSCI.22-02-00486.2002","article-title":"Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6","volume":"22","author":"Vallieres","year":"2002","journal-title":"J. Neurosci."},{"key":"B305","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/nature10357","article-title":"The ageing systemic milieu negatively regulates neurogenesis and cognitive function","volume":"477","author":"Villeda","year":"2011","journal-title":"Nature"},{"key":"B306","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1038\/nm.3569","article-title":"Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice","volume":"20","author":"Villeda","year":"2014","journal-title":"Nat. Med."},{"key":"B307","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.brainresbull.2009.01.004","article-title":"MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling","volume":"79","author":"Vrotsos","year":"2009","journal-title":"Brain Res. Bull."},{"key":"B308","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1002\/glia.20419","article-title":"Microglia instruct subventricular zone neurogenesis","volume":"54","author":"Walton","year":"2006","journal-title":"Glia"},{"key":"B309","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.neulet.2010.10.079","article-title":"Sustained increase in adult neurogenesis in the rat hippocampal dentate gyrus after transient brain ischemia","volume":"488","author":"Wang","year":"2011","journal-title":"Neurosci. Lett."},{"key":"B310","doi-asserted-by":"publisher","first-page":"361","DOI":"10.3389\/fncel.2015.00361","article-title":"Activated regulatory T cell regulates neural stem cell proliferation in the subventricular zone of normal and ischemic mouse brain through interleukin 10","volume":"9","author":"Wang","year":"2015","journal-title":"Front. Cell. Neurosci."},{"key":"B311","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.mcn.2007.07.005","article-title":"Interleukin-1\u03b2mediates proliferation and differentiation of multipotent neural precursor cells through the activation of SAPK\/JNK pathway","volume":"36","author":"Wang","year":"2007","journal-title":"Mol. Cell. Neurosci."},{"key":"B312","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1002\/ana.21457","article-title":"Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis","volume":"64","author":"Wang","year":"2008","journal-title":"Ann. Neurol."},{"key":"B313","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.scr.2012.12.003","article-title":"Stemformatics: visualisation and sharing of stem cell gene expression","volume":"10","author":"Wells","year":"2013","journal-title":"Stem Cell Res."},{"key":"B314","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/1471-2202-7-64","article-title":"Tumor necrosis factor alpha triggers proliferation of adult neural stem cells via IKK\/NF-\u03baB signaling","volume":"7","author":"Widera","year":"2006","journal-title":"BMC Neurosci."},{"key":"B315","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1002\/stem.1196","article-title":"Astrocytes negatively regulate neurogenesis through the Jagged1-mediated Notch pathway","volume":"30","author":"Wilhelmsson","year":"2012","journal-title":"Stem Cells"},{"key":"B316","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.bbi.2013.03.003","article-title":"Sustained IL-1\u03b2 expression impairs adult hippocampal neurogenesis independent of IL-1 signaling in nestin+ neural precursor cells","volume":"32","author":"Wu","year":"2013","journal-title":"Brain Behav. Immun."},{"key":"B317","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1038\/nature20411","article-title":"Ageing, neurodegeneration and brain rejuvenation","volume":"539","author":"Wyss-Coray","year":"2016","journal-title":"Nature"},{"key":"B318","doi-asserted-by":"publisher","first-page":"7990","DOI":"10.1038\/srep07990","article-title":"Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation","volume":"5","author":"Yang","year":"2015","journal-title":"Sci. Rep."},{"key":"B319","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1038\/nrn.2016.70","article-title":"Epigenetic mechanisms in neurogenesis","volume":"17","author":"Yao","year":"2016","journal-title":"Nat. Rev. Neurosci."},{"key":"B320","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.neuron.2009.09.035","article-title":"Taking advantage of the systemic immune system to cure brain diseases","volume":"64","author":"Yong","year":"2009","journal-title":"Neuron"},{"key":"B321","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fncel.2014.00010","article-title":"GABAergic striatal neurons project dendrites and axons into the postnatal subventricular zone leading to calcium activity","volume":"8","author":"Young","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"B322","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/scrt224","article-title":"Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery occlusion","volume":"4","author":"Yuan","year":"2013","journal-title":"Stem Cell Res. Ther."},{"key":"B323","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1007\/s11427-016-0114-9","article-title":"Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripotent stem cells","volume":"59","author":"Zhang","year":"2016","journal-title":"Sci. China Life Sci."},{"key":"B324","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1038\/nature12143","article-title":"Hypothalamic programming of systemic ageing involving IKK-\u03b2, NF-\u03baB and GnRH","volume":"497","author":"Zhang","year":"2013","journal-title":"Nature"},{"key":"B325","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1086\/677353","article-title":"Bioenergetic shifts during transitions between stem cell states (2013 Grover Conference series)","volume":"4","author":"Zhang","year":"2014","journal-title":"Pulm. Circ."},{"key":"B326","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1111\/j.1440-1789.2010.01182.x","article-title":"Human embryonic neural stem cell transplantation increases subventricular zone cell proliferation and promotes peri-infarct angiogenesis after focal cerebral ischemia","volume":"31","author":"Zhang","year":"2011","journal-title":"Neuropathology"},{"key":"B327","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1038\/jcbfm.2009.55","article-title":"Patterns and dynamics of subventricular zone neuroblast migration in the ischemic striatum of the adult mouse","volume":"29","author":"Zhang","year":"2009","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"B328","doi-asserted-by":"publisher","first-page":"e48141","DOI":"10.1371\/journal.pone.0048141","article-title":"Sildenafil enhances neurogenesis and oligodendrogenesis in ischemic brain of middle-aged mouse","volume":"7","author":"Zhang","year":"2012","journal-title":"PLoS ONE"},{"key":"B329","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0306-4522(01)00117-8","article-title":"Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia","volume":"105","author":"Zhang","year":"2001","journal-title":"Neuroscience"},{"key":"B330","doi-asserted-by":"publisher","first-page":"2659","DOI":"10.1007\/s12035-016-9851-0","article-title":"Exosomes derived from mesenchymal stromal cells promote axonal growth of cortical neurons","volume":"54","author":"Zhang","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"B331","doi-asserted-by":"publisher","first-page":"267","DOI":"10.5853\/jos.2016.00206","article-title":"Neural stem cells and ischemic brain","volume":"18","author":"Zhang","year":"2016","journal-title":"J Stroke"},{"key":"B332","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/j.cell.2008.01.033","article-title":"Mechanisms and functional implications of adult neurogenesis","volume":"132","author":"Zhao","year":"2008","journal-title":"Cell"},{"key":"B333","doi-asserted-by":"publisher","first-page":"e13374","DOI":"10.7554\/eLife.13374","article-title":"Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation","volume":"5","author":"Zheng","year":"2016","journal-title":"Elife"},{"key":"B334","doi-asserted-by":"publisher","first-page":"3866","DOI":"10.1096\/fj.08-105908","article-title":"Ramified microglial cells promote astrogliogenesis and maintenance of neural stem cells through activation of Stat3 function","volume":"22","author":"Zhu","year":"2008","journal-title":"FASEB J."},{"key":"B335","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1038\/nn1629","article-title":"Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood","volume":"9","author":"Ziv","year":"2006","journal-title":"Nat. Neurosci."}],"container-title":["Frontiers in Cell and Developmental Biology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcell.2017.00052\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T10:54:13Z","timestamp":1602068053000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcell.2017.00052\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,12]]},"references-count":335,"alternative-id":["10.3389\/fcell.2017.00052"],"URL":"https:\/\/doi.org\/10.3389\/fcell.2017.00052","relation":{},"ISSN":["2296-634X"],"issn-type":[{"value":"2296-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,12]]},"article-number":"52"}}