{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:06:09Z","timestamp":1790744769938,"version":"4.1.0"},"reference-count":151,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T00:00:00Z","timestamp":1580169600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell Dev. Biol."],"DOI":"10.3389\/fcell.2020.00006","type":"journal-article","created":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T04:25:50Z","timestamp":1580185550000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":77,"title":["Adherens Junctions: Guardians of Cortical Development"],"prefix":"10.3389","volume":"8","author":[{"given":"Lenin","family":"Veeraval","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conor J.","family":"O\u2019Leary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen M.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,1,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1006\/dbio.1996.0336","article-title":"Loss of occludin and functional tight junctions, but not ZO-1, during neural tube closure remodeling of the neuroepithelium prior to neurogenesis.","volume":"180","author":"Aaku-Saraste","year":"1996","journal-title":"Dev. Biol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1016\/j.devcel.2018.09.016","article-title":"A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress.","volume":"47","author":"Acharya","year":"2018","journal-title":"Dev. Cell"},{"key":"B3","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.neuron.2017.04.012","article-title":"Mosaic analysis with double markers reveals distinct sequential functions of Lgl1 in neural stem cells.","volume":"94","author":"Beattie","year":"2017","journal-title":"Neuron"},{"key":"B4","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1016\/j.neuron.2013.09.032","article-title":"Precursor diversity and complexity of lineage relationships in the outer subventricular zone of the primate.","volume":"80","author":"Betizeau","year":"2013","journal-title":"Neuron"},{"key":"B5","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.cub.2005.01.012","article-title":"Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.","volume":"15","author":"Betschinger","year":"2005","journal-title":"Curr. Biol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1038\/nature01486","article-title":"The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.","volume":"422","author":"Betschinger","year":"2003","journal-title":"Nature"},{"key":"B7","doi-asserted-by":"publisher","first-page":"12568","DOI":"10.1073\/pnas.1204390109","article-title":"E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch.","volume":"109","author":"Borghi","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a028746","article-title":"Signaling by small GTPases at cell-cell junctions: protein interactions building control and networks.","volume":"10","author":"Braga","year":"2017","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.ceb.2012.10.010","article-title":"Cadherin junctions and their cytoskeleton(s).","volume":"25","author":"Brieher","year":"2013","journal-title":"Curr. Opin. Cell Biol."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1126\/science.1254211","article-title":"The minimal cadherin-catenin complex binds to actin filaments under force.","volume":"346","author":"Buckley","year":"2014","journal-title":"Science"},{"key":"B11","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.neuron.2009.07.004","article-title":"Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex.","volume":"63","author":"Bultje","year":"2009","journal-title":"Neuron"},{"key":"B12","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.trsl.2019.02.014","article-title":"Role of adherens junctions and apical-basal polarity of neural stem\/progenitor cells in the pathogenesis of neurodevelopmental disorders: a novel perspective on congenital Zika syndrome.","volume":"210","author":"Bustamante","year":"2019","journal-title":"Trans. Res."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1038\/nn1744","article-title":"The Rho-GTPase Cdc42 regulates neural progenitor fate at the apical surface.","volume":"9","author":"Cappello","year":"2006","journal-title":"Nat. Neurosci."},{"key":"B14","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1016\/j.neuron.2011.12.030","article-title":"A radial glia-specific role of RhoA in double cortex formation.","volume":"73","author":"Cappello","year":"2012","journal-title":"Neuron"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1093\/hmg\/ddr531","article-title":"A glial origin for periventricular nodular heterotopia caused by impaired expression of Filamin-A.","volume":"21","author":"Carabalona","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"B16","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1038\/nsmb.3152","article-title":"Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation.","volume":"23","author":"Carminati","year":"2016","journal-title":"Nat. Struct. Mol. Biol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1038\/ng1302","article-title":"The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate.","volume":"36","author":"Chae","year":"2004","journal-title":"Nat. Genet."},{"key":"B18","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.cell.2013.11.048","article-title":"The WAVE regulatory complex links diverse receptors to the actin cytoskeleton.","volume":"156","author":"Chen","year":"2014","journal-title":"Cell"},{"key":"B19","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/nature09623","article-title":"Structure and control of the actin regulatory WAVE complex.","volume":"468","author":"Chen","year":"2010","journal-title":"Nature"},{"key":"B20","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1126\/science.1074192","article-title":"Regulation of cerebral cortical size by control of cell cycle exit in neural precursors.","volume":"297","author":"Chenn","year":"2002","journal-title":"Science"},{"key":"B21","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1126\/science.1247521","article-title":"Apical abscission alters cell polarity and dismantles the primary cilium during neurogenesis.","volume":"343","author":"Das","year":"2014","journal-title":"Science"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1111\/j.1471-4159.2008.05485.x","article-title":"Emerging roles for neogenin and its ligands in CNS development.","volume":"106","author":"De Vries","year":"2008","journal-title":"J. Neurochem."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1016\/j.cell.2008.07.017","article-title":"Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient.","volume":"134","author":"Del Bene","year":"2008","journal-title":"Cell"},{"key":"B24","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/s00401-009-0624-y","article-title":"Ependymal cells: biology and pathology.","volume":"119","author":"Del Bigio","year":"2010","journal-title":"Acta Neuropathol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1038\/nature04116","article-title":"Regulation of Lethal giant larvae by Dishevelled.","volume":"437","author":"Dollar","year":"2005","journal-title":"Nature"},{"key":"B26","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1097\/01.jnen.0000171648.86718.bb","article-title":"Ependymal denudation and alterations of the subventricular zone occur in human fetuses with a moderate communicating hydrocephalus.","volume":"64","author":"Dominguez-Pinos","year":"2005","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1016\/j.cell.2005.09.021","article-title":"Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.","volume":"123","author":"Drees","year":"2005","journal-title":"Cell"},{"key":"B28","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1146\/annurev.cellbio.23.090506.123249","article-title":"Cilia and developmental signaling.","volume":"23","author":"Eggenschwiler","year":"2007","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.tins.2010.10.002","article-title":"Development, specification, and diversity of callosal projection neurons.","volume":"34","author":"Fame","year":"2011","journal-title":"Trends Neurosci."},{"key":"B30","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1016\/j.ceb.2008.09.008","article-title":"The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development.","volume":"20","author":"Farkas","year":"2008","journal-title":"Curr. Opin. Cell Biol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1093\/hmg\/ddn377","article-title":"Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia.","volume":"18","author":"Ferland","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"B32","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1016\/s0896-6273(00)80651-0","article-title":"Mutations in Filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia.","volume":"21","author":"Fox","year":"1998","journal-title":"Neuron"},{"key":"B33","doi-asserted-by":"publisher","first-page":"10475","DOI":"10.1523\/JNEUROSCI.1793-14.2014","article-title":"Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon.","volume":"34","author":"Gil-Sanz","year":"2014","journal-title":"J. Neurosci."},{"key":"B34","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1097\/NEN.0000000000000203","article-title":"Cell junction pathology of neural stem cells is associated with ventricular zone disruption, hydrocephalus, and abnormal neurogenesis.","volume":"74","author":"Guerra","year":"2015","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"7764","DOI":"10.1074\/jbc.M113.544478","article-title":"Cortactin scaffolds Arp2\/3 and WAVE2 at the epithelial zonula adherens.","volume":"289","author":"Han","year":"2014","journal-title":"J. Biol. Chem."},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00176","article-title":"Cell polarity in cerebral cortex development - cellular architecture shaped by biochemical networks.","volume":"11","author":"Hansen","year":"2017","journal-title":"Front. Cell. Neurosci."},{"key":"B37","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1006\/dbio.2000.9962","article-title":"Characterization of CNS precursor subtypes and radial glia.","volume":"229","author":"Hartfuss","year":"2001","journal-title":"Dev. Biol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1242\/dev.102988","article-title":"Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates.","volume":"141","author":"Hatakeyama","year":"2014","journal-title":"Development"},{"key":"B39","doi-asserted-by":"publisher","first-page":"3245","DOI":"10.1242\/dev.02486","article-title":"Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes.","volume":"133","author":"Haubst","year":"2006","journal-title":"Development"},{"key":"B40","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1091\/mbc.E14-07-1200","article-title":"WAVE binds Ena\/VASP for enhanced Arp2\/3 complex-based actin assembly.","volume":"26","author":"Havrylenko","year":"2015","journal-title":"Mol. Biol. Cell"},{"key":"B41","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1038\/ncb923","article-title":"Direct interaction of two polarity complexes implicated in epithelial tight junction assembly.","volume":"5","author":"Hurd","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2019.00305","article-title":"Malformations of human neocortex in development \u2013 their progenitor cell basis and experimental model systems.","volume":"13","author":"Huttner","year":"2019","journal-title":"Front. Cell. Neurosci."},{"key":"B43","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.ceb.2005.10.005","article-title":"Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous system.","volume":"17","author":"Huttner","year":"2005","journal-title":"Curr. Opin. Cell Biol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1242\/dev.02330","article-title":"Inactivation of aPKC lambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.","volume":"133","author":"Imai","year":"2006","journal-title":"Development"},{"key":"B45","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1038\/nn.3336","article-title":"Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition like mechanism.","volume":"16","author":"Itoh","year":"2013","journal-title":"Nat. Neurosci."},{"key":"B46","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.expneurol.2014.01.011","article-title":"Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology.","volume":"254","author":"Jain","year":"2014","journal-title":"Exp. Neurol."},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068781","article-title":"GPR56 functions together with \u03b13\u03b21 integrin in regulating cerebral cortical development.","volume":"8","author":"Jeong","year":"2013","journal-title":"PLoS One"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.4161\/tisb.28426","article-title":"Structure and function of the ependymal barrier and diseases associated with ependyma disruption.","volume":"2","author":"Jimenez","year":"2014","journal-title":"Tissue Barriers"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1097\/NEN.0b013e3181b44a5a","article-title":"Disruption of the neurogenic niche in the subventricular zone of postnatal hydrocephalic hyh mice.","volume":"68","author":"Jim\u00e9nez","year":"2009","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.devcel.2017.05.002","article-title":"Llgl1 connects cell polarity with cell-cell adhesion in embryonic neural stem cells.","volume":"41","author":"Jossin","year":"2017","journal-title":"Dev. Cell"},{"key":"B51","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.ydbio.2006.12.014","article-title":"N-cadherin mediates cortical organization in the mouse brain.","volume":"304","author":"Kadowaki","year":"2007","journal-title":"Dev. Biol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1002\/cne.903390402","article-title":"Pyramidal neurons in layer 5 of the rat visual cortex. I. Correlation among cell morphology, intrinsic electrophysiological properties, and axon targets.","volume":"339","author":"Kasper","year":"1994","journal-title":"J. Comp. Neurol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"7607","DOI":"10.1073\/pnas.1101347108","article-title":"Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation.","volume":"108","author":"Katayama","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B54","doi-asserted-by":"publisher","first-page":"12643","DOI":"10.1523\/JNEUROSCI.4265-08.2008","article-title":"Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity.","volume":"28","author":"Kee","year":"2008","journal-title":"J. Neurosci."},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2013.00016","article-title":"The secondary loss of gyrencephaly as an example of evolutionary phenotypical reversal.","volume":"7","author":"Kelava","year":"2013","journal-title":"Front. Neuroanat."},{"key":"B56","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.neuron.2010.03.019","article-title":"The apical complex couples cell fate and cell survival to cerebral cortical development.","volume":"66","author":"Kim","year":"2010","journal-title":"Neuron"},{"key":"B57","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1101\/gad.1178004","article-title":"Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.","volume":"18","author":"Klezovitch","year":"2004","journal-title":"Genes Dev."},{"key":"B58","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/ncb1075","article-title":"Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables.","volume":"6","author":"Kobielak","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/ncb1673","article-title":"Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.","volume":"10","author":"Konno","year":"2008","journal-title":"Nat. Cell Biol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"2314","DOI":"10.1038\/sj.emboj.7600223","article-title":"Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells.","volume":"23","author":"Kosodo","year":"2004","journal-title":"EMBO J."},{"key":"B61","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1146\/annurev-neuro-070815-014023","article-title":"The genetic basis of hydrocephalus.","volume":"39","author":"Kousi","year":"2016","journal-title":"Ann. Rev. Neurosci."},{"key":"B62","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1038\/ncb2290","article-title":"N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway.","volume":"13","author":"Kovacs","year":"2011","journal-title":"Nat. Cell Biol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"2439","DOI":"10.1093\/cercor\/bhn260","article-title":"Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex.","volume":"19","author":"Kowalczyk","year":"2009","journal-title":"Cereb. Cortex"},{"key":"B64","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1146\/annurev.neuro.051508.135600","article-title":"The glial nature of embryonic and adult neural stem cells.","volume":"32","author":"Kriegstein","year":"2009","journal-title":"Ann. Rev. Neurosci."},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11082","article-title":"Neogenin recruitment of the WAVE Regulatory Complex maintains adherens junction stability and tension.","volume":"7","author":"Lee","year":"2016","journal-title":"Nat. Commun."},{"key":"B66","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/j.neuron.2011.01.023","article-title":"The cerebrospinal fluid provides a proliferative niche for neural progenitor cells.","volume":"69","author":"Lehtinen","year":"2011","journal-title":"Neuron"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00099","article-title":"Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia.","volume":"9","author":"Lian","year":"2015","journal-title":"Front. Cell. Neurosci."},{"key":"B68","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1126\/science.1121449","article-title":"Alpha E-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.","volume":"311","author":"Lien","year":"2006","journal-title":"Science"},{"key":"B69","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1016\/j.devcel.2012.04.010","article-title":"Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells.","volume":"22","author":"Linford","year":"2012","journal-title":"Dev. Cell"},{"key":"B70","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1038\/s41583-018-0112-2","article-title":"Deconstructing cortical folding: genetic, cellular and mechanical determinants.","volume":"20","author":"Llinares-Benadero","year":"2019","journal-title":"Nat. Rev. Neurosci."},{"key":"B71","doi-asserted-by":"publisher","first-page":"1744","DOI":"10.1091\/mbc.e04-10-0867","article-title":"Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin.","volume":"16","author":"Lock","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"B72","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1146\/annurev-cellbio-100814-125353","article-title":"Generating neuronal diversity in the mammalian cerebral cortex.","volume":"31","author":"Lodato","year":"2015","journal-title":"Ann. Rev. Cell Dev. Biol."},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000176","article-title":"\u03b21 integrin maintains integrity of the embryonic neocortical stem cell niche.","volume":"7","author":"Loulier","year":"2009","journal-title":"PLoS Biol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"2305","DOI":"10.1091\/mbc.e07-01-0073","article-title":"Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice.","volume":"18","author":"Ma","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"B75","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/s0306-4522(03)00519-0","article-title":"Role of beta-catenin in the developing cortical and hippocampal neuroepithelium.","volume":"122","author":"Machon","year":"2003","journal-title":"Neuroscience"},{"key":"B76","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1126\/science.1225399","article-title":"Adhesion functions in cell sorting by mechanically coupling the cortices of adhering cells.","volume":"338","author":"Ma\u00eetre","year":"2012","journal-title":"Science"},{"key":"B77","doi-asserted-by":"crossref","first-page":"5253","DOI":"10.1242\/dev.127.24.5253","article-title":"Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage.","volume":"127","author":"Malatesta","year":"2000","journal-title":"Development"},{"key":"B78","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1038\/embor.2009.36","article-title":"Adherens junction domains are split by asymmetric division of embryonic neural stem cells.","volume":"10","author":"Marthiens","year":"2009","journal-title":"EMBO Rep."},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11812","article-title":"A restricted period for formation of outer subventricular zone defined by Cdh1 and Trnp1 levels.","volume":"7","author":"Mart\u00ednez-Mart\u00ednez","year":"2016","journal-title":"Nat. Commun."},{"key":"B80","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1091\/mbc.01-07-0337","article-title":"Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism.","volume":"13","author":"Mary","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"B81","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/0165-3806(88)90043-0","article-title":"Mitotic cycling of radial glial cells of the fetal murine cerebral wall: a combined autoradiographic and immunohistochemical study.","volume":"466","author":"Misson","year":"1988","journal-title":"Brain Res."},{"key":"B82","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/s0896-6273(01)00420-2","article-title":"Asymmetric inheritance of radial glial fibers by cortical neurons.","volume":"31","author":"Miyata","year":"2001","journal-title":"Neuron"},{"key":"B83","doi-asserted-by":"publisher","first-page":"3133","DOI":"10.1242\/dev.01173","article-title":"Asymmetric production of surface-dividing and non-surface dividing cortical progenitor cells.","volume":"131","author":"Miyata","year":"2004","journal-title":"Development"},{"key":"B84","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/nrn2151","article-title":"Neuronal subtype specification in the cerebral cortex.","volume":"8","author":"Molyneaux","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"B85","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.cell.2010.02.040","article-title":"aPKC phosphorylation of Bazooka defines the apical\/lateral border in Drosophila epithelial cells.","volume":"141","author":"Morais-de-Sa","year":"2010","journal-title":"Cell"},{"key":"B86","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1006\/mcne.2002.1174","article-title":"Interkinetic nuclear movement may provide spatial clues to the regulation of neurogenesis.","volume":"21","author":"Murciano","year":"2002","journal-title":"Mol. Cell. Neurosci."},{"key":"B87","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/83967","article-title":"Two modes of radial migration in early development of the cerebral cortex.","volume":"4","author":"Nadarajah","year":"2001","journal-title":"Nat. Neurosci."},{"key":"B88","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.devcel.2007.07.017","article-title":"Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-\/- mice.","volume":"13","author":"Nechiporuk","year":"2007","journal-title":"Dev. Cell"},{"key":"B89","doi-asserted-by":"publisher","first-page":"3161","DOI":"10.1523\/jneurosci.22-08-03161.2002","article-title":"Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia.","volume":"22","author":"Noctor","year":"2002","journal-title":"J. Neurosci."},{"key":"B90","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1016\/j.cell.2017.05.016","article-title":"Wnt\/\u03b2-catenin signaling, disease, and emerging therapeutic modalities.","volume":"169","author":"Nusse","year":"2017","journal-title":"Cell"},{"key":"B91","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1038\/s41586-019-1515-6","article-title":"Temporal plasticity of apical progenitors in the developing mouse neocortex.","volume":"573","author":"Oberst","year":"2019","journal-title":"Nature"},{"key":"B92","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.neuron.2010.12.026","article-title":"Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells.","volume":"69","author":"Ohata","year":"2011","journal-title":"Neuron"},{"key":"B93","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1002\/stem.1861","article-title":"The Netrin\/RGM receptor, Neogenin, controls adult neurogenesis by promoting neuroblast migration and cell cycle exit.","volume":"33","author":"O\u2019Leary","year":"2015","journal-title":"Stem Cells"},{"key":"B94","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.celrep.2017.06.051","article-title":"Neogenin recruitment of the WAVE Regulatory Complex to ependymal and radial progenitor adherens junctions prevents hydrocephalus.","volume":"20","author":"O\u2019Leary","year":"2017","journal-title":"Cell Rep."},{"key":"B95","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/0896-6273(93)90049-w","article-title":"Development of projection neuron types, axon pathways, and patterned connections of the mammalian cortex.","volume":"10","author":"O\u2019Leary","year":"1993","journal-title":"Neuron"},{"key":"B96","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1097\/NEN.0b013e3182a2d5fe","article-title":"Disruption of CDH2\/N-cadherin-based adherens junctions leads to apoptosis of ependymal cells and denudation of brain ventricular walls.","volume":"72","author":"Oliver","year":"2013","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"B97","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.neuron.2019.01.051","article-title":"Adult neural stem cells and multiciliated ependymal cells share a common lineage regulated by the geminin family members.","volume":"102","author":"Ortiz-\u00c1lvarez","year":"2019","journal-title":"Neuron"},{"key":"B98","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1097\/nen.0b013e31815c1952","article-title":"Patterned neuropathologic events occurring in hyh congenital hydrocephalic mutant mice.","volume":"66","author":"Paez","year":"2007","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"B99","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1002\/embr.201438447","article-title":"Neurogenesis during development of the vertebrate central nervous system.","volume":"15","author":"Paridaen","year":"2014","journal-title":"EMBO Rep."},{"key":"B100","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.cell.2013.08.060","article-title":"Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division.","volume":"155","author":"Paridaen","year":"2013","journal-title":"Cell"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10329","article-title":"Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus.","volume":"7","author":"Park","year":"2016","journal-title":"Nat. Commun."},{"key":"B102","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.ceb.2019.05.002","article-title":"Switching states: dynamic remodelling of polarity complexes as a toolkit for cell polarization.","volume":"60","author":"Peglion","year":"2019","journal-title":"Curr. Opin. Cell Biol."},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2019.00305","article-title":"Malformations of human neocortex in development - their progenitor cell basis and experimental model systems.","volume":"13","author":"Pinson","year":"2019","journal-title":"Front. Cell. Neurosci."},{"key":"B104","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.tcb.2016.08.001","article-title":"The diverse family of Arp2\/3 complexes.","volume":"27","author":"Pizarro-Cerda","year":"2017","journal-title":"Trends Cell Biol."},{"key":"B105","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1038\/ncb948","article-title":"A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.","volume":"5","author":"Plant","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"B106","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.neuron.2011.09.022","article-title":"Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex.","volume":"72","author":"Postiglione","year":"2011","journal-title":"Neuron"},{"key":"B107","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/bs.ctdb.2014.11.016","article-title":"Active tension: the role of cadherin adhesion and signaling in generating junctional contractility.","volume":"112","author":"Priya","year":"2015","journal-title":"Curr. Top. Dev. Biol."},{"key":"B108","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1038\/ncb1156","article-title":"Neogenin mediates the action of repulsive guidance molecule.","volume":"6","author":"Rajagopalan","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1186\/s13064-017-0085-2","article-title":"Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia.","volume":"12","author":"Rakotomamonjy","year":"2017","journal-title":"Neural Dev."},{"key":"B110","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1038\/nn1924","article-title":"Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.","volume":"10","author":"Rasin","year":"2007","journal-title":"Nat. Neurosci."},{"key":"B111","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.celrep.2019.01.088","article-title":"Development of ependymal and postnatal neural stem cells and their origin from a common embryonic progenitor.","volume":"27","author":"Redmond","year":"2019","journal-title":"Cell Rep."},{"key":"B112","doi-asserted-by":"publisher","first-page":"1674","DOI":"10.1093\/cercor\/bhq238","article-title":"A role for intermediate radial glia in the tangential expansion of the mammalian cerebral cortex.","volume":"21","author":"Reillo","year":"2011","journal-title":"Cereb. Cortex"},{"key":"B113","doi-asserted-by":"publisher","first-page":"231","DOI":"10.4067\/S0716-97602012000300005","article-title":"A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus.","volume":"45","author":"Rodriguez","year":"2012","journal-title":"Biol. Res."},{"key":"B114","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/s0092-8674(00)80732-1","article-title":"The interaction between N-WASP and the Arp2\/3 complex links Cdc42-dependent signals to actin assembly.","volume":"97","author":"Rohatgi","year":"1999","journal-title":"Cell"},{"key":"B115","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1002\/cne.900620207","article-title":"Mitosis in the neural tube.","volume":"62","author":"Sauer","year":"1935","journal-title":"J. Comp. Neurol."},{"key":"B116","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1038\/s41588-018-0166-0","article-title":"Biallelic loss of human CTNNA2, encoding \u03b1N-catenin, leads to ARP2\/3 complex overactivity and disordered cortical neuronal migration.","volume":"50","author":"Schaffer","year":"2018","journal-title":"Nat. Genet."},{"key":"B117","doi-asserted-by":"publisher","first-page":"3674","DOI":"10.1016\/j.cub.2018.10.002","article-title":"Distinct interaction sites of Rac GTPase with WAVE regulatory complex have non-redundant functions in vivo.","volume":"28","author":"Schaks","year":"2018","journal-title":"Curr. Biol."},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2014.00215","article-title":"The role of \u03b1-E-catenin in cerebral cortex development: radial glia specific effect on neuronal migration.","volume":"8","author":"Schmid","year":"2014","journal-title":"Front. Cell. Neurosci."},{"key":"B119","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.braindev.2003.09.004","article-title":"Etiological heterogeneity of familial periventricular heterotopia and hydrocephalus.","volume":"26","author":"Sheen","year":"2004","journal-title":"Brain Dev."},{"key":"B120","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/ng1276","article-title":"Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex.","volume":"36","author":"Sheen","year":"2003","journal-title":"Nat. Genet."},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.4161\/tisb.29431","article-title":"Filamin A mediated Big2 dependent endocytosis: from apical abscission to periventricular heterotopia.","volume":"2","author":"Sheen","year":"2014","journal-title":"Tissue Barriers"},{"key":"B122","doi-asserted-by":"publisher","first-page":"3683","DOI":"10.1523\/JNEUROSCI.4773-10.2011","article-title":"Oblique radial glial divisions in the developing mouse neocortex induce self-renewing progenitors outside the germinal zone that resemble primate outer subventricular zone progenitors.","volume":"31","author":"Shitamukai","year":"2011","journal-title":"J. Neurosci."},{"key":"B123","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.tcb.2016.11.009","article-title":"RGMs: structural insights, molecular regulation, and downstream signaling.","volume":"27","author":"Siebold","year":"2017","journal-title":"Trends Cell Biol."},{"key":"B124","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.tibs.2017.03.002","article-title":"Functional actin networks under construction: the cooperative action of actin nucleation and elongation factors.","volume":"42","author":"Siton-Mendelson","year":"2017","journal-title":"Trends Biochem. Sci."},{"key":"B125","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1093\/cercor\/12.1.37","article-title":"Unique morphological features of the proliferative zones and postmitotic compartments of the neural epithelium giving rise to striate and extrastriate cortex in the monkey.","volume":"12","author":"Smart","year":"2002","journal-title":"Cereb. Cortex"},{"key":"B126","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022458","article-title":"Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherens.","volume":"6","author":"Smutny","year":"2011","journal-title":"PLoS One"},{"key":"B127","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1523\/jneurosci.1108-04.2005","article-title":"Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis.","volume":"25","author":"Spassky","year":"2005","journal-title":"J. Neurosci."},{"key":"B128","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1080\/19336918.2015.1027478","article-title":"The role of adherens junctions in the developing neocortex.","volume":"9","author":"Stocker","year":"2015","journal-title":"Cell Adh. Migr."},{"key":"B129","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1146\/annurev-neuro-071714-034128","article-title":"Cortical folding: when, where, how and why?","volume":"38","author":"Striedter","year":"2015","journal-title":"Ann. Rev. Neurosci."},{"key":"B130","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1016\/s0092-8674(00)81050-8","article-title":"Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization.","volume":"84","author":"Symons","year":"1996","journal-title":"Cell"},{"key":"B131","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1038\/ncb896","article-title":"Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.","volume":"5","author":"Tanentzapf","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"B132","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1016\/j.neuron.2018.01.052","article-title":"Insm1 induces neural progenitor delamination in developing neocortex via downregulation of the adherens junction belt-specific protein Plekha7.","volume":"97","author":"Tavano","year":"2018","journal-title":"Neuron"},{"key":"B133","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1146\/annurev-cellbio-101011-155801","article-title":"The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex.","volume":"30","author":"Taverna","year":"2014","journal-title":"Ann. Rev. Cell Dev. Biol."},{"key":"B134","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1016\/j.neuron.2010.08.027","article-title":"Neural progenitor nuclei IN motion.","volume":"67","author":"Taverna","year":"2010","journal-title":"Neuron"},{"key":"B135","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025465","article-title":"Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia.","volume":"6","author":"Thumkeo","year":"2011","journal-title":"PLoS One"},{"key":"B136","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1093\/cercor\/13.6.580","article-title":"Postnatal development of radial glia and the ventricular zone (VZ): a continuum of the neural stem cell compartment.","volume":"13","author":"Tramontin","year":"2003","journal-title":"Cereb. Cortex"},{"key":"B137","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1002\/cne.1125","article-title":"Structural abnormalities develop in the brain after ablation of the gene encoding nonmuscle myosin II-B heavy chain.","volume":"433","author":"Tullio","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"B138","doi-asserted-by":"publisher","first-page":"4601","DOI":"10.1091\/mbc.E12-08-0574","article-title":"A WAVE2-Arp2\/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens.","volume":"23","author":"Verma","year":"2012","journal-title":"Mol. Biol. Cell"},{"key":"B139","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1016\/j.cell.2018.06.036","article-title":"Progenitor hyperpolarization regulates the sequential generation of neuronal subtypes in the developing neocortex.","volume":"174","author":"Vitali","year":"2018","journal-title":"Cell"},{"key":"B140","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/j.cub.2010.04.049","article-title":"Crumbs\/DaPKC-dependent apical exclusion of Bazooka promotes photoreceptor polarity remodeling.","volume":"20","author":"Walther","year":"2010","journal-title":"Curr. Biol."},{"key":"B141","doi-asserted-by":"publisher","first-page":"2741","DOI":"10.1242\/dev.130542","article-title":"Crucial roles of the Arp2\/3 complex during mammalian corticogenesis.","volume":"143","author":"Wang","year":"2016","journal-title":"Development"},{"key":"B142","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1038\/nature08435","article-title":"Asymmetric centrosome inheritance maintains neural progenitors in the neocortex.","volume":"461","author":"Wang","year":"2009","journal-title":"Nature"},{"key":"B143","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1242\/dev.069294","article-title":"Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination.","volume":"139","author":"Wilsch-Brauninger","year":"2012","journal-title":"Development"},{"key":"B144","doi-asserted-by":"publisher","first-page":"12620","DOI":"10.1523\/jneurosci.3180-06.2006","article-title":"Cell-autonomous beta-catenin signaling regulates cortical precursor proliferation.","volume":"26","author":"Woodhead","year":"2006","journal-title":"J. Neurosci."},{"key":"B145","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1038\/ncb2900","article-title":"Cortical F-actin stabilization generates apical-lateral patterns of junctional contractility that integrate cells into epithelia.","volume":"16","author":"Wu","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080356","article-title":"Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain.","volume":"8","author":"Yamamoto","year":"2013","journal-title":"PLoS One"},{"key":"B147","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1016\/s0960-9822(03)00244-6","article-title":"Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.","volume":"13","author":"Yamanaka","year":"2003","journal-title":"Curr. Biol."},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a028761","article-title":"Mechanosensing and mechanotransduction at cell-cell junctions.","volume":"10","author":"Yap","year":"2017","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"B149","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.stem.2014.05.003","article-title":"Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity.","volume":"15","author":"Yoon","year":"2014","journal-title":"Cell Stem Cell"},{"key":"B150","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.stem.2017.07.014","article-title":"Zika virus-encoded NS2a disrupts mammalian cortical neurogenesis by degrading adherens junction proteins.","volume":"21","author":"Yoon","year":"2017","journal-title":"Cell Stem Cell"},{"key":"B151","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.neuroscience.2018.12.039","article-title":"Loss of Lgl1 disrupts the radial glial fiber-guided cortical neuronal migration and causes subcortical band heterotopia in mice.","volume":"400","author":"Zhang","year":"2019","journal-title":"Neuroscience"}],"container-title":["Frontiers in Cell and Developmental Biology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcell.2020.00006\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T02:11:49Z","timestamp":1665627109000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcell.2020.00006\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,28]]},"references-count":151,"alternative-id":["10.3389\/fcell.2020.00006"],"URL":"https:\/\/doi.org\/10.3389\/fcell.2020.00006","relation":{},"ISSN":["2296-634X"],"issn-type":[{"value":"2296-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,28]]},"article-number":"6"}}