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Absence of the nutrients and hypoxia trigger the cells\u2019 mortality in the core of the tumors of humans\u2019 brains: however, type of the cells\u2019 mortality, including apoptosis or necrosis, has been not found obviously. Current studies have emphasized the non-coding RNAs (ncRNAs) since their crucial impacts on carcinogenesis have been discovered. Several investigations suggest the essential contribution of such molecules in the development of brain tumors and the respective roles in apoptosis. Herein, we summarize the apoptosis-related non-coding RNAs in brain tumors.<\/jats:p>","DOI":"10.3389\/fcell.2021.792185","type":"journal-article","created":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T06:56:36Z","timestamp":1642402596000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":21,"title":["Non-Coding RNAs and Brain Tumors: Insights Into Their Roles in Apoptosis"],"prefix":"10.3389","volume":"9","author":[{"given":"Omid Reza","family":"Tamtaji","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Derakhshan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh Zahra","family":"Rashidi Noshabad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javad","family":"Razaviyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Razie","family":"Hadavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamed","family":"Jafarpour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ameneh","family":"Jafari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Rajabi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Hamblin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmood Khaksary","family":"Mahabady","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Taghizadieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamed","family":"Mirzaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,1,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1016\/j.tplants.2016.09.003","article-title":"miRNA Biogenesis: a Dynamic Pathway","volume":"21","author":"Achkar","year":"2016","journal-title":"Trends Plant Sci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1038\/s41571-019-0177-5","article-title":"Challenges to Curing Primary Brain Tumours","volume":"16","author":"Aldape","year":"2019","journal-title":"Nat. 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