{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:26:52Z","timestamp":1790728012394,"version":"4.1.0"},"reference-count":380,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell Dev. Biol."],"abstract":"<jats:p>Macrophages are one of the most functionally diverse immune cells, indispensable to maintain tissue integrity and metabolic health. Macrophages perform a myriad of functions ranging from promoting inflammation, through inflammation resolution to restoring and maintaining tissue homeostasis. Metabolic diseases encompass a growing list of diseases which develop from a mix of genetics and environmental cues leading to metabolic dysregulation and subsequent inflammation. In this review, we summarize the contributions of macrophages to four metabolic conditions\u2013insulin resistance and adipose tissue inflammation, atherosclerosis, non-alcoholic fatty liver disease and neurodegeneration. The role of macrophages is complex, yet they hold great promise as potential therapies to address these growing health concerns.<\/jats:p>","DOI":"10.3389\/fcell.2023.1147434","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T11:53:22Z","timestamp":1678708402000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":28,"title":["The diverse roles of macrophages in metabolic inflammation and its resolution"],"prefix":"10.3389","volume":"11","author":[{"given":"Aleepta","family":"Guha Ray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwatomilayo Patience","family":"Odum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Destini","family":"Wiseman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ada","family":"Weinstock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,3,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"CD003177","DOI":"10.1002\/14651858.CD003177.pub4","article-title":"Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease","volume":"11","author":"Abdelhamid","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1161\/CIRCRESAHA.120.317914","article-title":"miR-33 silencing reprograms the immune cell landscape in atherosclerotic plaques","volume":"128","author":"Afonso","year":"2021","journal-title":"Circ. Res."},{"key":"B3","doi-asserted-by":"crossref","first-page":"e21665","DOI":"10.1096\/fj.202100543RR","article-title":"Macrophage tumor necrosis factor-alpha deletion does not protect against obesity-associated metabolic dysfunction","volume":"35","author":"Aladhami","year":"2021","journal-title":"FASEB J."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1161\/CIRCULATIONAHA.113.005015","article-title":"Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis","volume":"129","author":"Allahverdian","year":"2014","journal-title":"Circulation"},{"key":"B5","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1038\/s42255-022-00551-7","article-title":"Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution","volume":"4","author":"Ampomah","year":"2022","journal-title":"Nat. Metab."},{"key":"B6","doi-asserted-by":"publisher","first-page":"e76564","DOI":"10.7554\/eLife.76564","article-title":"Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence","volume":"11","author":"Anderson","year":"2022","journal-title":"Elife"},{"key":"B7","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/s0021-9150(97)00136-6","article-title":"Subendothelial smooth muscle cells of human aorta express macrophage antigen in situ and in vitro","volume":"135","author":"Andreeva","year":"1997","journal-title":"Atherosclerosis"},{"key":"B8","doi-asserted-by":"publisher","first-page":"E374","DOI":"10.1152\/ajpendo.00187.2014","article-title":"Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance","volume":"307","author":"Aouadi","year":"2014","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"B9","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1161\/hq1201.099426","article-title":"Transforming growth factor-beta1 inhibits macrophage cholesteryl ester accumulation induced by native and oxidized VLDL remnants","volume":"21","author":"Argmann","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"26043","DOI":"10.1074\/jbc.m115.679043","article-title":"Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2)","volume":"290","author":"Atagi","year":"2015","journal-title":"J. Biol. Chem."},{"key":"B11","doi-asserted-by":"publisher","first-page":"4855","DOI":"10.4049\/jimmunol.1602175","article-title":"The upregulation of integrin \u03b1D\u03b22 (CD11d\/CD18) on inflammatory macrophages promotes macrophage retention in vascular lesions and development of atherosclerosis","volume":"198","author":"Aziz","year":"2017","journal-title":"J. Immunol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.cmet.2008.09.005","article-title":"Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis","volume":"8","author":"Babaev","year":"2008","journal-title":"Cell Metab."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1172\/JCI6117","article-title":"Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo","volume":"103","author":"Babaev","year":"1999","journal-title":"J. Clin. Invest"},{"key":"B14","doi-asserted-by":"publisher","first-page":"26293","DOI":"10.1074\/jbc.M002423200","article-title":"Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low-density lipoprotein receptor-deficient mice","volume":"275","author":"Babaev","year":"2000","journal-title":"J. Biol. Chem."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1161\/01.ATV.0000173413.31789.1a","article-title":"Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL\/6 and low-density lipoprotein receptor-deficient mice","volume":"25","author":"Babaev","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1136\/gutjnl-2011-300304","article-title":"Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury","volume":"61","author":"Baeck","year":"2012","journal-title":"Gut"},{"key":"B17","first-page":"142","article-title":"The epidemic of obesity and diabetes: Trends and treatments","volume":"38","author":"Barnes","year":"2011","journal-title":"Tex Heart Inst. J."},{"key":"B18","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/nri.2015.4","article-title":"Specialized pro-resolving mediators: Endogenous regulators of infection and inflammation","volume":"16","author":"Basil","year":"2016","journal-title":"Nat. Rev. Immunol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1007\/s00401-016-1595-4","article-title":"High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia","volume":"132","author":"Baufeld","year":"2016","journal-title":"Acta Neuropathol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/s0008-6363(03)00464-4","article-title":"Chronic inhibition of cyclooxygenase-2 does not alter plaque composition in a mouse model of advanced unstable atherosclerosis","volume":"60","author":"Bea","year":"2003","journal-title":"Cardiovasc Res."},{"key":"B21","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.cmet.2013.04.021","article-title":"Reciprocal regulation of hepatic and adipose lipogenesis by liver X receptors in obesity and insulin resistance","volume":"18","author":"Beaven","year":"2013","journal-title":"Cell Metab."},{"key":"B22","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1161\/CIRCRESAHA.115.306361","article-title":"Vascular smooth muscle cells in atherosclerosis","volume":"118","author":"Bennett","year":"2016","journal-title":"Circ. Res."},{"key":"B23","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.cmet.2013.10.003","article-title":"Weighing in on adipocyte precursors","volume":"19","author":"Berry","year":"2014","journal-title":"Cell Metab."},{"key":"B24","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1056\/NEJMoa1812792","article-title":"Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia","volume":"380","author":"Bhatt","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"B25","doi-asserted-by":"publisher","first-page":"e34378","DOI":"10.1371\/journal.pone.0034378","article-title":"Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells","volume":"7","author":"Bieghs","year":"2012","journal-title":"PLoS One"},{"key":"B26","doi-asserted-by":"publisher","first-page":"2477","DOI":"10.1053\/j.gastro.2010.02.051","article-title":"Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice","volume":"138","author":"Bieghs","year":"2010","journal-title":"Gastroenterology"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1136\/gutjnl-2016-313654","article-title":"Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice","volume":"67","author":"Bijnen","year":"2018","journal-title":"Gut"},{"key":"B28","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1016\/j.immuni.2021.08.006","article-title":"A subset of Kupffer cells regulates metabolism through the expression of CD36","volume":"54","author":"Bleriot","year":"2021","journal-title":"Immunity"},{"key":"B29","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/j.jhep.2013.04.025","article-title":"Food-derived peroxidized fatty acids may trigger hepatic inflammation: A novel hypothesis to explain steatohepatitis","volume":"59","author":"Bohm","year":"2013","journal-title":"J. Hepatol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1038\/29788","article-title":"Decreased lesion formation in CCR2-\/- mice reveals a role for chemokines in the initiation of atherosclerosis","volume":"394","author":"Boring","year":"1998","journal-title":"Nature"},{"key":"B31","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.cmet.2007.06.010","article-title":"PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties","volume":"6","author":"Bouhlel","year":"2007","journal-title":"Cell Metab."},{"key":"B32","doi-asserted-by":"publisher","first-page":"e0159679","DOI":"10.1371\/journal.pone.0159679","article-title":"Divergent JAM-C expression accelerates monocyte-derived cell exit from atherosclerotic plaques","volume":"11","author":"Bradfield","year":"2016","journal-title":"PLoS One"},{"key":"B33","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1161\/01.atv.0000253886.44609.ae","article-title":"Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice","volume":"27","author":"Braunersreuther","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1007\/s00125-005-1682-x","article-title":"Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: Sites and mechanisms","volume":"48","author":"Bugianesi","year":"2005","journal-title":"Diabetologia"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1816","DOI":"10.1161\/01.cir.0000014927.74465.7f","article-title":"Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice","volume":"105","author":"Burleigh","year":"2002","journal-title":"Circulation"},{"key":"B36","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.cmet.2019.11.013","article-title":"Macrophage MerTK promotes liver fibrosis in nonalcoholic steatohepatitis","volume":"31","author":"Cai","year":"2020","journal-title":"Cell Metab."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aar3721","article-title":"MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity","volume":"11","author":"Cai","year":"2018","journal-title":"Sci. Signal"},{"key":"B38","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1172\/JCI90520","article-title":"MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis","volume":"127","author":"Cai","year":"2017","journal-title":"J. Clin. Invest"},{"key":"B39","doi-asserted-by":"publisher","first-page":"e131355","DOI":"10.1172\/jci.insight.131355","article-title":"STAT6\/Arg1 promotes microglia\/macrophage efferocytosis and inflammation resolution in stroke mice","volume":"4","author":"Cai","year":"2019","journal-title":"JCI Insight"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1505S","DOI":"10.1093\/ajcn\/83.6.1505S","article-title":"n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases","volume":"83","author":"Calder","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"B41","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1007\/bf03402102","article-title":"Interleukin-10 deficiency increases atherosclerosis, thrombosis, and low-density lipoproteins in apolipoprotein E knockout mice","volume":"9","author":"Caligiuri","year":"2003","journal-title":"Mol. Med."},{"key":"B42","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s00401-015-1388-1","article-title":"TREM2 regulates microglial cell activation in response to demyelination in vivo","volume":"129","author":"Cantoni","year":"2015","journal-title":"Acta Neuropathol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1111\/j.1365-2036.2006.02885.x","article-title":"Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: A pilot study","volume":"23","author":"Capanni","year":"2006","journal-title":"Aliment. Pharmacol. Ther."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1002\/emmm.201201374","article-title":"Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype","volume":"4","author":"Cardilo-Reis","year":"2012","journal-title":"EMBO Mol. Med."},{"key":"B45","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/j.1365-2567.2011.03514.x","article-title":"miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production","volume":"135","author":"Cardoso","year":"2012","journal-title":"Immunology"},{"key":"B46","doi-asserted-by":"publisher","first-page":"984859","DOI":"10.3389\/fimmu.2022.984859","article-title":"Weight cycling induces innate immune memory in adipose tissue macrophages","volume":"13","author":"Caslin","year":"2022","journal-title":"Front. Immunol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s40659-020-00280-9","article-title":"Inhibition of miR-19a-3p decreases cerebral ischemia\/reperfusion injury by targeting IGFBP3 in vivo and in vitro","volume":"53","author":"Chai","year":"2020","journal-title":"Biol. Res."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1161\/ATVBAHA.119.312389","article-title":"Role of LpL (lipoprotein lipase) in macrophage polarization in vitro and in vivo","volume":"39","author":"Chang","year":"2019","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"3595","DOI":"10.1167\/iovs.05-1522","article-title":"Potential role of microglia in retinal blood vessel formation","volume":"47","author":"Checchin","year":"2006","journal-title":"Invest Ophthalmol. Vis. Sci."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.5754\/hge11903","article-title":"Selective depletion of hepatic Kupffer cells significantly alleviated hepatosteatosis and intrahepatic inflammation induced by high fat diet","volume":"59","author":"Chen","year":"2012","journal-title":"Hepatogastroenterology"},{"key":"B51","doi-asserted-by":"publisher","first-page":"e52835","DOI":"10.15252\/embr.202152835","article-title":"Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice","volume":"22","author":"Chen","year":"2021","journal-title":"EMBO Rep."},{"key":"B52","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1161\/ATVBAHA.119.313633","article-title":"MicroRNA-144 silencing protects against atherosclerosis in male, but not female mice","volume":"40","author":"Cheng","year":"2020","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1038\/ncpcardio0195","article-title":"Mechanisms of disease: Macrophage-derived foam cells emerging as therapeutic targets in atherosclerosis","volume":"2","author":"Choudhury","year":"2005","journal-title":"Nat. Clin. Pract. Cardiovasc Med."},{"key":"B54","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1002\/hep.26351","article-title":"C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice","volume":"58","author":"Chu","year":"2013","journal-title":"Hepatology"},{"key":"B55","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1194\/jlr.M001602","article-title":"FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa\/fa) obese rats","volume":"51","author":"Cipriani","year":"2010","journal-title":"J. Lipid Res."},{"key":"B56","doi-asserted-by":"publisher","first-page":"C1141","DOI":"10.1152\/ajpcell.00351.2012","article-title":"Diversity of lipid mediators in human adipose tissue depots","volume":"304","author":"Claria","year":"2013","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1161\/01.ATV.0000178994.21828.a7","article-title":"The farnesoid X receptor: A molecular link between bile acid and lipid and glucose metabolism","volume":"25","author":"Claudel","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1016\/j.cmet.2021.06.012","article-title":"FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption","volume":"33","author":"Clifford","year":"2021","journal-title":"Cell Metab."},{"key":"B59","doi-asserted-by":"publisher","first-page":"3149","DOI":"10.1016\/j.celrep.2017.08.096","article-title":"Metabolically activated adipose tissue macrophages perform detrimental and beneficial functions during diet-induced obesity","volume":"20","author":"Coats","year":"2017","journal-title":"Cell Rep."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1161\/CIRCRESAHA.117.312509","article-title":"Single-cell RNA-seq reveals the transcriptional landscape and heterogeneity of aortic macrophages in murine atherosclerosis","volume":"122","author":"Cochain","year":"2018","journal-title":"Circ. Res."},{"key":"B61","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.1161\/CIRCULATIONAHA.107.745091","article-title":"Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice","volume":"117","author":"Combadiere","year":"2008","journal-title":"Circulation"},{"key":"B62","first-page":"62","article-title":"The origin of foam cells in atherosclerosis","volume":"52","author":"Cookson","year":"1971","journal-title":"Br. J. Exp. Pathol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"2950","DOI":"10.1038\/s41467-022-30646-4","article-title":"Multiomics reveals persistence of obesity-associated immune cell phenotypes in adipose tissue during weight loss and weight regain in mice","volume":"13","author":"Cottam","year":"2022","journal-title":"Nat. Commun."},{"key":"B64","doi-asserted-by":"publisher","first-page":"eabe9383","DOI":"10.1126\/science.abe9383","article-title":"Diet-regulated production of PDGFcc by macrophages controls energy storage","volume":"373","author":"Cox","year":"2021","journal-title":"Science"},{"key":"B65","doi-asserted-by":"publisher","first-page":"e0129251","DOI":"10.1371\/journal.pone.0129251","article-title":"MicroRNA-155 deficiency attenuates liver steatosis and fibrosis without reducing inflammation in a mouse model of steatohepatitis","volume":"10","author":"Csak","year":"2015","journal-title":"PLoS One"},{"key":"B66","doi-asserted-by":"publisher","first-page":"13121","DOI":"10.3390\/ijms232113121","article-title":"Circulating soluble TREM2 and cardiovascular outcome in cohort study of coronary atherosclerosis patients","volume":"23","author":"Cuciuc","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B67","doi-asserted-by":"publisher","first-page":"eabf7844","DOI":"10.1126\/science.abf7844","article-title":"Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma","volume":"373","author":"Cugurra","year":"2021","journal-title":"Science"},{"key":"B68","doi-asserted-by":"publisher","first-page":"108626","DOI":"10.1016\/j.celrep.2020.108626","article-title":"Dynamic shifts in the composition of resident and recruited macrophages influence tissue remodeling in NASH","volume":"34","author":"Daemen","year":"2021","journal-title":"Cell Rep."},{"key":"B69","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.1161\/CIRCULATIONAHA.116.026560","article-title":"Causal associations of adiposity and body fat distribution with coronary heart disease, stroke subtypes, and type 2 diabetes mellitus: A mendelian randomization analysis","volume":"135","author":"Dale","year":"2017","journal-title":"Circulation"},{"key":"B70","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1161\/CIRCRESAHA.112.300648","article-title":"MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor","volume":"112","author":"de Aguiar Vallim","year":"2013","journal-title":"Circ. Res."},{"key":"B71","doi-asserted-by":"publisher","first-page":"E713","DOI":"10.1152\/ajpendo.00194.2007","article-title":"Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity","volume":"293","author":"De Taeye","year":"2007","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"B72","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1016\/j.it.2018.01.012","article-title":"Lipid droplets as immune modulators in myeloid cells","volume":"39","author":"den Brok","year":"2018","journal-title":"Trends Immunol."},{"key":"B73","doi-asserted-by":"publisher","first-page":"315","DOI":"10.3945\/jn.112.171322","article-title":"Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-\/-) mouse model of Western diet-induced nonalcoholic steatohepatitis","volume":"143","author":"Depner","year":"2013","journal-title":"J. Nutr."},{"key":"B74","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1084\/jem.192.5.695","article-title":"Inhibition of E-selectin gene expression by transforming growth factor beta in endothelial cells involves coactivator integration of Smad and nuclear factor kappaB-mediated signals","volume":"192","author":"DiChiara","year":"2000","journal-title":"J. Exp. Med."},{"key":"B75","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1161\/CIRCRESAHA.115.304164","article-title":"miR33 inhibition overcomes deleterious effects of diabetes mellitus on atherosclerosis plaque regression in mice","volume":"115","author":"Distel","year":"2014","journal-title":"Circ. Res."},{"key":"B76","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1161\/ATVBAHA.107.159327","article-title":"Role of smooth muscle cells in the initiation and early progression of atherosclerosis","volume":"28","author":"Doran","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.4049\/jimmunol.161.3.1471","article-title":"IL-10 regulates thrombus-induced vein wall inflammation and thrombosis","volume":"161","author":"Downing","year":"1998","journal-title":"J. Immunol."},{"key":"B78","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1053\/j.gastro.2015.05.044","article-title":"Association of adipose tissue inflammation with histologic severity of nonalcoholic fatty liver disease","volume":"149","author":"du Plessis","year":"2015","journal-title":"Gastroenterology"},{"key":"B79","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1002\/glia.24179","article-title":"Microglia maintain the normal structure and function of the hippocampal astrocyte network","volume":"70","author":"Du","year":"2022","journal-title":"Glia"},{"key":"B80","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1161\/ATVBAHA.121.315849","article-title":"How single-cell technologies have provided new insights into atherosclerosis","volume":"42","author":"Eberhardt","year":"2022","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B81","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1161\/ATVBAHA.122.317583","article-title":"Myeloid LXR (liver X receptor) deficiency induces inflammatory gene expression in foamy macrophages and accelerates atherosclerosis","volume":"42","author":"Endo-Umeda","year":"2022","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B82","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1038\/ni.3343","article-title":"Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth","volume":"17","author":"Ensan","year":"2016","journal-title":"Nat. Immunol."},{"key":"B83","doi-asserted-by":"publisher","first-page":"2618","DOI":"10.1523\/JNEUROSCI.4200-13.2014","article-title":"Obesity elicits interleukin 1-mediated deficits in hippocampal synaptic plasticity","volume":"34","author":"Erion","year":"2014","journal-title":"J. Neurosci."},{"key":"B84","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1002\/hep.23280","article-title":"Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications","volume":"51","author":"Fabbrini","year":"2010","journal-title":"Hepatology"},{"key":"B85","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1186\/s12944-021-01518-5","article-title":"Low serum maresin-1 levels are associated with non-alcoholic fatty liver disease: A cross-sectional study","volume":"20","author":"Fang","year":"2021","journal-title":"Lipids Health Dis."},{"key":"B86","volume-title":"IDF diabetes atlas","author":"Federation","year":"2021"},{"key":"B87","doi-asserted-by":"publisher","first-page":"4415","DOI":"10.1172\/JCI38911","article-title":"LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression","volume":"120","author":"Feig","year":"2010","journal-title":"J. Clin. Invest"},{"key":"B88","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1161\/CIRCRESAHA.115.306300","article-title":"MicroRNA regulation of atherosclerosis","volume":"118","author":"Feinberg","year":"2016","journal-title":"Circ. Res."},{"key":"B89","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1038\/s41591-019-0590-4","article-title":"Single-cell immune landscape of human atherosclerotic plaques","volume":"25","author":"Fernandez","year":"2019","journal-title":"Nat. Med."},{"key":"B90","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pharmthera.2017.07.010","article-title":"The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease","volume":"181","author":"Fessler","year":"2018","journal-title":"Pharmacol. Ther."},{"key":"B91","doi-asserted-by":"publisher","first-page":"12859","DOI":"10.1038\/ncomms12859","article-title":"An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques","volume":"7","author":"Fredman","year":"2016","journal-title":"Nat. Commun."},{"key":"B92","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1016\/j.ajpath.2017.01.018","article-title":"Boosting inflammation resolution in atherosclerosis: The next frontier for therapy","volume":"187","author":"Fredman","year":"2017","journal-title":"Am. J. Pathol."},{"key":"B93","doi-asserted-by":"publisher","first-page":"281","DOI":"10.2174\/1568010054022024","article-title":"Macrophages in inflammation","volume":"4","author":"Fujiwara","year":"2005","journal-title":"Curr. Drug Targets Inflamm. Allergy"},{"key":"B94","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1002\/hep.26937","article-title":"The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease","volume":"59","author":"Gadd","year":"2014","journal-title":"Hepatology"},{"key":"B95","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1161\/01.atv.15.7.949","article-title":"TGF-beta and endothelial cells inhibit VCAM-1 expression on human vascular smooth muscle cells","volume":"15","author":"Gamble","year":"1995","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B96","doi-asserted-by":"publisher","first-page":"E289","DOI":"10.1152\/ajpendo.00430.2013","article-title":"Interleukin-1\u03b2 mediates macrophage-induced impairment of insulin signaling in human primary adipocytes","volume":"307","author":"Gao","year":"2014","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"B97","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1016\/j.cmet.2022.05.008","article-title":"MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH","volume":"34","author":"Gao","year":"2022","journal-title":"Cell Metab."},{"key":"B98","doi-asserted-by":"publisher","first-page":"2451","DOI":"10.3390\/cells10092451","article-title":"Adipose tissue macrophages modulate obesity-associated beta cell adaptations through secreted miRNA-containing extracellular vesicles","volume":"10","author":"Gao","year":"2021","journal-title":"Cells"},{"key":"B99","doi-asserted-by":"publisher","first-page":"3034","DOI":"10.1016\/j.celrep.2017.09.008","article-title":"Lipoprotein lipase maintains microglial innate immunity in obesity","volume":"20","author":"Gao","year":"2017","journal-title":"Cell Rep."},{"key":"B100","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.cell.2005.08.032","article-title":"Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte","volume":"123","author":"Gardai","year":"2005","journal-title":"Cell"},{"key":"B101","doi-asserted-by":"publisher","first-page":"33652","DOI":"10.1074\/jbc.M110.152090","article-title":"Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation","volume":"285","author":"Gerin","year":"2010","journal-title":"J. Biol. Chem."},{"key":"B102","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1038\/s41418-019-0370-1","article-title":"Resolvin D1 promotes the targeting and clearance of necroptotic cells","volume":"27","author":"Gerlach","year":"2020","journal-title":"Cell Death Differ."},{"key":"B103","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1126\/science.1194637","article-title":"Fate mapping analysis reveals that adult microglia derive from primitive macrophages","volume":"330","author":"Ginhoux","year":"2010","journal-title":"Science"},{"key":"B104","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/nature13989","article-title":"Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors","volume":"518","author":"Gomez Perdiguero","year":"2015","journal-title":"Nature"},{"key":"B105","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1096\/fj.08-125674","article-title":"Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: A role for resolvins and protectins","volume":"23","author":"Gonzalez-Periz","year":"2009","journal-title":"FASEB J."},{"key":"B106","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1186\/s12915-017-0392-4","article-title":"Tissue macrophages: Heterogeneity and functions","volume":"15","author":"Gordon","year":"2017","journal-title":"BMC Biol."},{"key":"B107","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1016\/j.jhep.2021.12.012","article-title":"Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease","volume":"76","author":"Govaere","year":"2022","journal-title":"J. Hepatol."},{"key":"B108","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1021\/cb300541g","article-title":"A liver-selective LXR inverse agonist that suppresses hepatic steatosis","volume":"8","author":"Griffett","year":"2013","journal-title":"ACS Chem. Biol."},{"key":"B109","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/s1097-2765(00)80139-2","article-title":"Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low-density lipoprotein receptor-deficient mice","volume":"2","author":"Gu","year":"1998","journal-title":"Mol. Cell"},{"key":"B110","doi-asserted-by":"publisher","first-page":"4623","DOI":"10.1038\/s41467-021-24540-8","article-title":"Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice","volume":"12","author":"Guo","year":"2021","journal-title":"Nat. Commun."},{"key":"B111","doi-asserted-by":"publisher","first-page":"1961","DOI":"10.1172\/JCI126078","article-title":"Visceral adipose NLRP3 impairs cognition in obesity via IL-1R1 on CX3CR1+ cells","volume":"130","author":"Guo","year":"2020","journal-title":"J. Clin. Invest"},{"key":"B112","doi-asserted-by":"publisher","first-page":"1828","DOI":"10.1002\/hep.28406","article-title":"Activation of liver X receptor\/retinoid X receptor pathway ameliorates liver disease in Atp7B(-\/-) (Wilson disease) mice","volume":"63","author":"Hamilton","year":"2016","journal-title":"Hepatology"},{"key":"B113","doi-asserted-by":"publisher","first-page":"2751","DOI":"10.1073\/pnas.1920004117","article-title":"Regulation of adipose tissue inflammation by interleukin 6","volume":"117","author":"Han","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B114","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1172\/JCI124219","article-title":"A maresin 1\/ROR\u03b1\/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis","volume":"129","author":"Han","year":"2019","journal-title":"J. Clin. Invest"},{"key":"B115","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.cld.2015.10.008","article-title":"Effect of weight loss, diet, exercise, and bariatric surgery on nonalcoholic fatty liver disease","volume":"20","author":"Hannah","year":"2016","journal-title":"Clin. Liver Dis."},{"key":"B116","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.cyto.2012.02.010","article-title":"Atherogenic effects of TNF-alpha and IL-6 via up-regulation of scavenger receptors","volume":"58","author":"Hashizume","year":"2012","journal-title":"Cytokine"},{"key":"B117","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1126\/science.abj8894","article-title":"Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation","volume":"379","author":"Hata","year":"2023","journal-title":"Science"},{"key":"B118","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1161\/CIRCRESAHA.119.315897","article-title":"Treatment of obesity in mitigating metabolic risk","volume":"126","author":"Heffron","year":"2020","journal-title":"Circ. Res."},{"key":"B119","doi-asserted-by":"publisher","first-page":"2399","DOI":"10.1096\/fj.10-178657","article-title":"Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice","volume":"25","author":"Hellmann","year":"2011","journal-title":"FASEB J."},{"key":"B120","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.4049\/jimmunol.1203369","article-title":"Increased saturated fatty acids in obesity alter resolution of inflammation in part by stimulating prostaglandin production","volume":"191","author":"Hellmann","year":"2013","journal-title":"J. Immunol."},{"key":"B121","doi-asserted-by":"publisher","first-page":"893","DOI":"10.3389\/fimmu.2018.00893","article-title":"Peroxisome proliferator-activated receptor-gamma modulates the response of macrophages to lipopolysaccharide and glucocorticoids","volume":"9","author":"Heming","year":"2018","journal-title":"Front. Immunol."},{"key":"B122","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1016\/j.jhep.2022.06.004","article-title":"Soluble TREM2 levels reflect the recruitment and expansion of TREM2(+) macrophages that localize to fibrotic areas and limit NASH","volume":"77","author":"Hendrikx","year":"2022","journal-title":"J. Hepatol."},{"key":"B123","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1038\/nature11729","article-title":"NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP\/PS1 mice","volume":"493","author":"Heneka","year":"2013","journal-title":"Nature"},{"key":"B124","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.4049\/jimmunol.164.4.2131","article-title":"Viral IL-10 gene transfer decreases inflammation and cell adhesion molecule expression in a rat model of venous thrombosis","volume":"164","author":"Henke","year":"2000","journal-title":"J. Immunol."},{"key":"B125","doi-asserted-by":"publisher","first-page":"1658","DOI":"10.1172\/JCI31561","article-title":"Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones","volume":"117","author":"Hevener","year":"2007","journal-title":"J. Clin. Invest"},{"key":"B126","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1111\/j.1872-034x.2008.00382.x","article-title":"Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease","volume":"38","author":"Higuchi","year":"2008","journal-title":"Hepatol. Res."},{"key":"B127","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1053\/j.gastro.2015.12.037","article-title":"Lipid-induced signaling causes release of inflammatory extracellular vesicles from hepatocytes","volume":"150","author":"Hirsova","year":"2016","journal-title":"Gastroenterology"},{"key":"B128","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.immuni.2015.03.011","article-title":"C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages","volume":"42","author":"Hoeffel","year":"2015","journal-title":"Immunity"},{"key":"B129","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1038\/nrd4280","article-title":"Liver X receptors in lipid metabolism: Opportunities for drug discovery","volume":"13","author":"Hong","year":"2014","journal-title":"Nat. Rev. Drug Discov."},{"key":"B130","doi-asserted-by":"publisher","first-page":"2525","DOI":"10.2337\/db08-1261","article-title":"Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle","volume":"58","author":"Hong","year":"2009","journal-title":"Diabetes"},{"key":"B131","doi-asserted-by":"publisher","first-page":"17321","DOI":"10.1073\/pnas.1008499107","article-title":"MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo","volume":"107","author":"Horie","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B132","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1126\/science.7678183","article-title":"Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance","volume":"259","author":"Hotamisligil","year":"1993","journal-title":"Science"},{"key":"B133","doi-asserted-by":"publisher","first-page":"e135197","DOI":"10.1172\/JCI135197","article-title":"TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis","volume":"131","author":"Hou","year":"2021","journal-title":"J. Clin. Invest"},{"key":"B134","doi-asserted-by":"publisher","first-page":"56","DOI":"10.3389\/fgene.2012.00056","article-title":"Exosomal miRNAs: Biological properties and therapeutic potential","volume":"3","author":"Hu","year":"2012","journal-title":"Front. Genet."},{"key":"B135","doi-asserted-by":"publisher","first-page":"e94997","DOI":"10.1371\/journal.pone.0094997","article-title":"An agomir of miR-144-3p accelerates plaque formation through impairing reverse cholesterol transport and promoting pro-inflammatory cytokine production","volume":"9","author":"Hu","year":"2014","journal-title":"PLoS One"},{"key":"B136","doi-asserted-by":"publisher","first-page":"347","DOI":"10.2337\/db09-0016","article-title":"Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance","volume":"59","author":"Huang","year":"2010","journal-title":"Diabetes"},{"key":"B137","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1002\/hep.28252","article-title":"Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes","volume":"63","author":"Ibrahim","year":"2016","journal-title":"Hepatology"},{"key":"B138","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1194\/jlr.M034876","article-title":"Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis","volume":"54","author":"Ioannou","year":"2013","journal-title":"J. Lipid Res."},{"key":"B139","doi-asserted-by":"publisher","first-page":"100330","DOI":"10.1016\/j.jlr.2023.100330","article-title":"Genetic deletion or pharmacologic inhibition of the Nlrp3 Inflammasome did not ameliorate experimental NASH","volume":"64","author":"Ioannou","year":"2023","journal-title":"J. Lipid Res."},{"key":"B140","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1194\/jlr.M072454","article-title":"Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH","volume":"58","author":"Ioannou","year":"2017","journal-title":"J. Lipid Res."},{"key":"B141","doi-asserted-by":"publisher","first-page":"35715","DOI":"10.1074\/jbc.M804220200","article-title":"Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue","volume":"283","author":"Ito","year":"2008","journal-title":"J. Biol. Chem."},{"key":"B142","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1016\/j.cell.2019.05.054","article-title":"Lipid-associated macrophages control metabolic homeostasis in a trem2-dependent manner","volume":"178","author":"Jaitin","year":"2019","journal-title":"Cell"},{"key":"B143","doi-asserted-by":"publisher","first-page":"e2630","DOI":"10.1097\/md.0000000000002630","article-title":"Prediction of nonalcoholic fatty liver disease via a novel panel of serum adipokines","volume":"95","author":"Jamali","year":"2016","journal-title":"Med. Baltim."},{"key":"B144","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1084\/jem.20060245","article-title":"Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis","volume":"203","author":"Jongstra-Bilen","year":"2006","journal-title":"J. Exp. Med."},{"key":"B145","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1161\/CIRCRESAHA.120.317458","article-title":"Atherosclerosis regression and cholesterol efflux in hypertriglyceridemic mice","volume":"128","author":"Josefs","year":"2021","journal-title":"Circ. Res."},{"key":"B146","doi-asserted-by":"publisher","first-page":"7604","DOI":"10.1073\/pnas.112059299","article-title":"Synthetic LXR ligand inhibits the development of atherosclerosis in mice","volume":"99","author":"Joseph","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B147","doi-asserted-by":"publisher","first-page":"26602","DOI":"10.1074\/jbc.M601284200","article-title":"Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance","volume":"281","author":"Kamei","year":"2006","journal-title":"J. Biol. Chem."},{"key":"B148","doi-asserted-by":"publisher","first-page":"1494","DOI":"10.1172\/JCI26498","article-title":"MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity","volume":"116","author":"Kanda","year":"2006","journal-title":"J. Clin. Invest"},{"key":"B149","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1002\/hep.22950","article-title":"Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis","volume":"50","author":"Karlmark","year":"2009","journal-title":"Hepatology"},{"key":"B150","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1111\/liv.13150","article-title":"The macrophage activation marker sCD163 is associated with morphological disease stages in patients with non-alcoholic fatty liver disease","volume":"36","author":"Kazankov","year":"2016","journal-title":"Liver Int."},{"key":"B151","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1111\/jgh.12943","article-title":"Macrophage activation marker soluble CD163 and non-alcoholic fatty liver disease in morbidly obese patients undergoing bariatric surgery","volume":"30","author":"Kazankov","year":"2015","journal-title":"J. Gastroenterol. Hepatol."},{"key":"B152","doi-asserted-by":"publisher","first-page":"105684","DOI":"10.1016\/j.nbd.2022.105684","article-title":"Co-expression patterns of microglia markers Iba1, TMEM119 and P2RY12 in Alzheimer's disease","volume":"167","author":"Kenkhuis","year":"2022","journal-title":"Neurobiol. Dis."},{"key":"B153","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1016\/j.cell.2017.05.018","article-title":"A unique microglia type associated with restricting development of alzheimer's disease","volume":"169","author":"Keren-Shaul","year":"2017","journal-title":"Cell"},{"key":"B154","doi-asserted-by":"publisher","first-page":"C1442","DOI":"10.1152\/ajpcell.2001.281.5.C1442","article-title":"Essential role of ICAM-1 in mediating monocyte adhesion to aortic endothelial cells","volume":"281","author":"Kevil","year":"2001","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"B155","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/s1098-3597(99)90002-9","article-title":"Obesity and its comorbid conditions","volume":"2","author":"Khaodhiar","year":"1999","journal-title":"Clin. Cornerstone"},{"key":"B156","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.immuni.2020.11.007","article-title":"A binary cre transgenic approach dissects microglia and CNS border-associated macrophages","volume":"54","author":"Kim","year":"2021","journal-title":"Immunity"},{"key":"B157","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.expneurol.2011.11.010","article-title":"MiR-106b impairs cholesterol efflux and increases A\u03b2 levels by repressing ABCA1 expression","volume":"235","author":"Kim","year":"2012","journal-title":"Exp. Neurol."},{"key":"B158","doi-asserted-by":"publisher","first-page":"2798","DOI":"10.1002\/hep4.2057","article-title":"Cellular communication network factor 1-stimulated liver macrophage efferocytosis drives hepatic stellate cell activation and liver fibrosis","volume":"6","author":"Kim","year":"2022","journal-title":"Hepatol. Commun."},{"key":"B159","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1161\/CIRCRESAHA.118.312804","article-title":"Transcriptome analysis reveals nonfoamy rather than foamy plaque macrophages are proinflammatory in atherosclerotic murine models","volume":"123","author":"Kim","year":"2018","journal-title":"Circ. Res."},{"key":"B160","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1161\/hq0302.104905","article-title":"Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-\/- mice","volume":"22","author":"King","year":"2002","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B161","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1016\/j.jmb.2017.04.004","article-title":"TREM2-Ligand interactions in health and disease","volume":"429","author":"Kober","year":"2017","journal-title":"J. Mol. Biol."},{"key":"B162","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1053\/j.gastro.2009.06.045","article-title":"c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice","volume":"137","author":"Kodama","year":"2009","journal-title":"Gastroenterology"},{"key":"B163","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1038\/nature18935","article-title":"CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis","volume":"536","author":"Kojima","year":"2016","journal-title":"Nature"},{"key":"B164","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.1002\/hep.29544","article-title":"Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis","volume":"67","author":"Krenkel","year":"2018","journal-title":"Hepatology"},{"key":"B165","doi-asserted-by":"publisher","first-page":"1574","DOI":"10.1016\/j.celrep.2014.10.068","article-title":"Adipocyte-specific IKK\u03b2 signaling suppresses adipose tissue inflammation through an IL-13-dependent paracrine feedback pathway","volume":"9","author":"Kwon","year":"2014","journal-title":"Cell Rep."},{"key":"B166","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1172\/JCI118286","article-title":"IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes","volume":"96","author":"Lacraz","year":"1995","journal-title":"J. Clin. Invest"},{"key":"B167","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1038\/ijo.2017.226","article-title":"Maresin 1 mitigates liver steatosis in ob\/ob and diet-induced obese mice","volume":"42","author":"Laiglesia","year":"2018","journal-title":"Int. J. Obes. (Lond)"},{"key":"B168","doi-asserted-by":"publisher","first-page":"G107","DOI":"10.1152\/ajpgi.00391.2009","article-title":"Kupffer cell activation is a causal factor for hepatic insulin resistance","volume":"298","author":"Lanthier","year":"2010","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"B169","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1056\/nejmoa065213","article-title":"Interleukin-1-receptor antagonist in type 2 diabetes mellitus","volume":"356","author":"Larsen","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"B170","doi-asserted-by":"publisher","first-page":"2358","DOI":"10.1038\/s41467-020-16080-4","article-title":"N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer's disease","volume":"11","author":"Lee","year":"2020","journal-title":"Nat. Commun."},{"key":"B171","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1038\/s42255-022-00643-4","article-title":"Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to beta-amyloid clearance","volume":"4","author":"Leng","year":"2022","journal-title":"Nat. Metab."},{"key":"B172","doi-asserted-by":"publisher","first-page":"2443","DOI":"10.1172\/JCI119786","article-title":"In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13","volume":"100","author":"Lentsch","year":"1997","journal-title":"J. Clin. Invest"},{"key":"B173","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1172\/JCI15555","article-title":"Decreased atherosclerosis in CX3CR1-\/- mice reveals a role for fractalkine in atherogenesis","volume":"111","author":"Lesnik","year":"2003","journal-title":"J. Clin. Invest"},{"key":"B174","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1161\/01.ATV.0000150044.84012.68","article-title":"Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists","volume":"25","author":"Levin","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B175","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1111\/obr.12407","article-title":"Obesity is an independent risk factor for non-alcoholic fatty liver disease: Evidence from a meta-analysis of 21 cohort studies","volume":"17","author":"Li","year":"2016","journal-title":"Obes. Rev."},{"key":"B176","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/nri.2017.125","article-title":"Microglia and macrophages in brain homeostasis and disease","volume":"18","author":"Li","year":"2018","journal-title":"Nat. Rev. Immunol."},{"key":"B177","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1161\/circresaha.109.199570","article-title":"Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob\/ob mice and reversal by a fish oil diet","volume":"105","author":"Li","year":"2009","journal-title":"Circ. Res."},{"key":"B178","doi-asserted-by":"publisher","first-page":"13005","DOI":"10.18632\/aging.103387","article-title":"MicroRNA-124 inhibits macrophage cell apoptosis via targeting p38\/MAPK signaling pathway in atherosclerosis development","volume":"12","author":"Liang","year":"2020","journal-title":"Aging (Albany NY)"},{"key":"B179","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1038\/nature01323","article-title":"Inflammation in atherosclerosis","volume":"420","author":"Libby","year":"2002","journal-title":"Nature"},{"key":"B180","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"},{"key":"B181","volume-title":"Obesity and comorbid conditions","author":"Lim","year":"2022"},{"key":"B182","doi-asserted-by":"publisher","first-page":"e124574","DOI":"10.1172\/jci.insight.124574","article-title":"Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression","volume":"4","author":"Lin","year":"2019","journal-title":"JCI Insight"},{"key":"B183","doi-asserted-by":"publisher","first-page":"2259","DOI":"10.1253\/circj.CJ-16-0924","article-title":"Macrophage apoptosis and efferocytosis in the pathogenesis of atherosclerosis","volume":"80","author":"Linton","year":"2016","journal-title":"Circ. J."},{"key":"B184","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1161\/ATVBAHA.112.300068","article-title":"MicroRNAs in immune response and macrophage polarization","volume":"33","author":"Liu","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B185","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1002\/hep.31050","article-title":"Lipotoxic hepatocyte-derived exosomal MicroRNA 192-5p activates macrophages through rictor\/akt\/forkhead Box transcription factor O1 signaling in nonalcoholic fatty liver disease","volume":"72","author":"Liu","year":"2020","journal-title":"Hepatology"},{"key":"B186","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1007\/s10620-011-1902-9","article-title":"Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease","volume":"57","author":"Liu","year":"2012","journal-title":"Dig. Dis. Sci."},{"key":"B187","doi-asserted-by":"publisher","first-page":"34","DOI":"10.3969\/j.issn.1671-5411.2013.01.007","article-title":"Circulating miR-214 is associated with the severity of coronary artery disease","volume":"10","author":"Lu","year":"2013","journal-title":"J. Geriatr. Cardiol."},{"key":"B188","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1172\/JCI29881","article-title":"Obesity induces a phenotypic switch in adipose tissue macrophage polarization","volume":"117","author":"Lumeng","year":"2007","journal-title":"J. Clin. Invest"},{"key":"B189","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.bbadis.2018.10.005","article-title":"The deficiency of macrophage erythropoietin signaling contributes to delayed acute inflammation resolution in diet-induced obese mice","volume":"1865","author":"Luo","year":"2019","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"B190","doi-asserted-by":"publisher","first-page":"44612","DOI":"10.1038\/srep44612","article-title":"Effect of modulation of PPAR-gamma activity on Kupffer cells M1\/M2 polarization in the development of non-alcoholic fatty liver disease","volume":"7","author":"Luo","year":"2017","journal-title":"Sci. Rep."},{"key":"B191","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/s10571-016-0361-4","article-title":"MicroRNA-27a negatively modulates the inflammatory response in lipopolysaccharide-stimulated microglia by targeting TLR4 and IRAK4","volume":"37","author":"Lv","year":"2017","journal-title":"Cell Mol. Neurobiol."},{"key":"B192","doi-asserted-by":"publisher","first-page":"2833","DOI":"10.1074\/mcp.M112.026864","article-title":"Activated cyclin-dependent kinase 5 promotes microglial phagocytosis of fibrillar beta-amyloid by up-regulating lipoprotein lipase expression","volume":"12","author":"Ma","year":"2013","journal-title":"Mol. Cell Proteomics"},{"key":"B193","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1002\/eji.200636398","article-title":"PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells","volume":"37","author":"Majai","year":"2007","journal-title":"Eur. J. Immunol."},{"key":"B194","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1152\/physrev.00061.2009","article-title":"Hepatocyte death: A clear and present danger","volume":"90","author":"Malhi","year":"2010","journal-title":"Physiol. Rev."},{"key":"B195","doi-asserted-by":"publisher","first-page":"e17","DOI":"10.1161\/01.res.85.8.e17","article-title":"Protective role of interleukin-10 in atherosclerosis","volume":"85","author":"Mallat","year":"1999","journal-title":"Circ. Res."},{"key":"B196","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1161\/01.atv.19.3.611","article-title":"Expression of interleukin-10 in advanced human atherosclerotic plaques: Relation to inducible nitric oxide synthase expression and cell death","volume":"19","author":"Mallat","year":"1999","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B197","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1172\/JCI17223","article-title":"Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes","volume":"111","author":"Matsusue","year":"2003","journal-title":"J. Clin. Invest"},{"key":"B198","doi-asserted-by":"publisher","first-page":"2431","DOI":"10.1007\/s00125-010-1865-y","article-title":"Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance","volume":"53","author":"Matthews","year":"2010","journal-title":"Diabetologia"},{"key":"B199","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.4049\/jimmunol.1000520","article-title":"IL-33 reduces macrophage foam cell formation","volume":"185","author":"McLaren","year":"2010","journal-title":"J. Immunol."},{"key":"B200","doi-asserted-by":"publisher","first-page":"11761","DOI":"10.1074\/jbc.M112.446575","article-title":"Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease","volume":"288","author":"McMahan","year":"2013","journal-title":"J. Biol. Chem."},{"key":"B201","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1007\/s00109-002-0384-9","article-title":"Lipoprotein lipase: Structure, function, regulation, and role in disease","volume":"80","author":"Mead","year":"2002","journal-title":"J. Mol. Med. Berl."},{"key":"B202","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1161\/01.res.0000028008.99774.7f","article-title":"Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice","volume":"91","author":"Mehrabian","year":"2002","journal-title":"Circ. Res."},{"key":"B203","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1016\/j.bbadis.2012.06.002","article-title":"TGF-Beta inhibits the uptake of modified low-density lipoprotein by human macrophages through a smad-dependent pathway: A dominant role for smad-2","volume":"1822","author":"Michael","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"B204","doi-asserted-by":"publisher","first-page":"2069","DOI":"10.1016\/j.bbalip.2016.01.011","article-title":"Lipoprotein carriers of microRNAs","volume":"1861","author":"Michell","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"B205","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1161\/CIRCRESAHA.110.218867","article-title":"Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice","volume":"107","author":"Miller","year":"2010","journal-title":"Circ. Res."},{"key":"B206","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1084\/jem.20071868","article-title":"IL-33 reduces the development of atherosclerosis","volume":"205","author":"Miller","year":"2008","journal-title":"J. Exp. Med."},{"key":"B207","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1038\/s41366-018-0114-1","article-title":"MicroRNA-30 modulates metabolic inflammation by regulating Notch signaling in adipose tissue macrophages","volume":"42","author":"Miranda","year":"2018","journal-title":"Int. J. Obes. (Lond)"},{"key":"B208","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.bbi.2015.08.010","article-title":"Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation","volume":"53","author":"Miro-Mur","year":"2016","journal-title":"Brain Behav. Immun."},{"key":"B209","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1038\/nature05449","article-title":"The nuclear receptor LXR is a glucose sensor","volume":"445","author":"Mitro","year":"2007","journal-title":"Nature"},{"key":"B210","doi-asserted-by":"publisher","first-page":"G1310","DOI":"10.1152\/ajpgi.00365.2011","article-title":"Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2","volume":"302","author":"Miura","year":"2012","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"B211","doi-asserted-by":"publisher","first-page":"12540","DOI":"10.1038\/ncomms12540","article-title":"Microglia contact induces synapse formation in developing somatosensory cortex","volume":"7","author":"Miyamoto","year":"2016","journal-title":"Nat. Commun."},{"key":"B212","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1038\/s41569-021-00569-6","article-title":"PPAR control of metabolism and cardiovascular functions","volume":"18","author":"Montaigne","year":"2021","journal-title":"Nat. Rev. Cardiol."},{"key":"B213","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1016\/j.jhep.2013.06.023","article-title":"Cell-specific PPAR\u03b3 deficiency establishes anti-inflammatory and anti-fibrogenic properties for this nuclear receptor in non-parenchymal liver cells","volume":"59","author":"Moran-Salvador","year":"2013","journal-title":"J. Hepatol."},{"key":"B214","doi-asserted-by":"publisher","first-page":"3770","DOI":"10.2337\/db13-1495","article-title":"Fractalkine (CX3CL1) is involved in the early activation of hypothalamic inflammation in experimental obesity","volume":"63","author":"Morari","year":"2014","journal-title":"Diabetes"},{"key":"B215","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.2337\/db14-1238","article-title":"Characterization of distinct subpopulations of hepatic macrophages in HFD\/obese mice","volume":"64","author":"Morinaga","year":"2015","journal-title":"Diabetes"},{"key":"B216","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1053\/j.gastro.2013.05.042","article-title":"Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease","volume":"145","author":"Mudaliar","year":"2013","journal-title":"Gastroenterology"},{"key":"B217","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1161\/ATVBAHA.121.316854","article-title":"Macrophage LRP1 (Low-Density lipoprotein receptor-related protein 1) is required for the effect of CD47 blockade on efferocytosis and atherogenesis-brief report","volume":"42","author":"Mueller","year":"2022","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B218","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1161\/01.ATV.0000132401.12275.0c","article-title":"Atherosclerotic plaque smooth muscle cells have a distinct phenotype","volume":"24","author":"Mulvihill","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B219","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.cmet.2014.03.029","article-title":"Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity","volume":"19","author":"Nagareddy","year":"2014","journal-title":"Cell Metab."},{"key":"B220","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1126\/science.1189123","article-title":"MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis","volume":"328","author":"Najafi-Shoushtari","year":"2010","journal-title":"Science"},{"key":"B221","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1016\/s0140-6736(14)61933-4","article-title":"Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): A multicentre, randomised, placebo-controlled trial","volume":"385","author":"Neuschwander-Tetri","year":"2015","journal-title":"Lancet"},{"key":"B222","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.bbrc.2009.05.070","article-title":"Critical role of Kupffer cells in the management of diet-induced diabetes and obesity","volume":"385","author":"Neyrinck","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B223","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1161\/ATVBAHA.117.309795","article-title":"Extracellular vesicles secreted by atherogenic macrophages transfer MicroRNA to inhibit cell migration","volume":"38","author":"Nguyen","year":"2018","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B224","doi-asserted-by":"publisher","first-page":"2118","DOI":"10.1002\/hep.31906","article-title":"T-cell immunoglobulin and mucin domain-containing protein-4 is critical for kupffer cell homeostatic function in the activation and resolution of liver ischemia reperfusion injury","volume":"74","author":"Ni","year":"2021","journal-title":"Hepatology"},{"key":"B225","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1001\/jamaneurol.2022.0976","article-title":"Risk factors associated with alzheimer disease and related dementias by sex and race and ethnicity in the US","volume":"79","author":"Nianogo","year":"2022","journal-title":"JAMA Neurol."},{"key":"B226","doi-asserted-by":"publisher","first-page":"2268","DOI":"10.1001\/jama.2020.22258","article-title":"Effect of high-dose omega-3 fatty acids vs corn oil on major adverse cardiovascular events in patients at high cardiovascular risk: The STRENGTH randomized clinical trial","volume":"324","author":"Nicholls","year":"2020","journal-title":"JAMA"},{"key":"B227","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.ahj.2019.09.011","article-title":"The effect of low-dose colchicine in patients with stable coronary artery disease: The LoDoCo2 trial rationale, design, and baseline characteristics","volume":"218","author":"Nidorf","year":"2019","journal-title":"Am. Heart J."},{"key":"B228","doi-asserted-by":"publisher","first-page":"233","DOI":"10.2337\/db21-1072","article-title":"Prostaglandin PGE2 receptor EP4 regulates microglial phagocytosis and increases susceptibility to diet-induced obesity","volume":"72","author":"Niraula","year":"2022","journal-title":"Diabetes"},{"key":"B229","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.clnu.2015.05.001","article-title":"Omega-3 polyunsaturated fatty acids in treating non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial","volume":"35","author":"Nogueira","year":"2016","journal-title":"Clin. Nutr."},{"key":"B230","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/j.neuron.2019.12.007","article-title":"TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge","volume":"105","author":"Nugent","year":"2020","journal-title":"Neuron"},{"key":"B231","doi-asserted-by":"publisher","first-page":"916","DOI":"10.2337\/db09-1403","article-title":"C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis","volume":"59","author":"Obstfeld","year":"2010","journal-title":"Diabetes"},{"key":"B232","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1038\/nature05894","article-title":"Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance","volume":"447","author":"Odegaard","year":"2007","journal-title":"Nature"},{"key":"B233","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1126\/science.288.5473.2051","article-title":"Role of CD47 as a marker of self on red blood cells","volume":"288","author":"Oldenborg","year":"2000","journal-title":"Science"},{"key":"B234","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1080\/140174302762659094","article-title":"No effect of cyclooxygenase inhibition on plaque size in atherosclerosis-prone mice","volume":"36","author":"Olesen","year":"2002","journal-title":"Scand. Cardiovasc J."},{"key":"B235","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1093\/brain\/awv379","article-title":"Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology","volume":"139","author":"Olmos-Alonso","year":"2016","journal-title":"Brain"},{"key":"B236","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1007\/s00018-022-04649-9","article-title":"Deleting interleukin-10 from myeloid cells exacerbates atherosclerosis in Apoe(-\/-) mice","volume":"80","author":"Orecchioni","year":"2022","journal-title":"Cell Mol. Life Sci."},{"key":"B237","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1159\/000250095","article-title":"Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis","volume":"47","author":"Orr","year":"2010","journal-title":"J. Vasc. Res."},{"key":"B238","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1161\/ATVBAHA.116.308916","article-title":"microRNA-33 regulates macrophage autophagy in atherosclerosis","volume":"37","author":"Ouimet","year":"2017","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B239","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1161\/ATVBAHA.107.156935","article-title":"Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels","volume":"28","author":"Out","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B240","doi-asserted-by":"publisher","first-page":"10640","DOI":"10.1096\/fj.202000830R","article-title":"Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner","volume":"34","author":"Pal","year":"2020","journal-title":"FASEB J."},{"key":"B241","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1086\/342259","article-title":"Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype","volume":"71","author":"Paloneva","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"B242","doi-asserted-by":"publisher","first-page":"2060","DOI":"10.1161\/CIRCULATIONAHA.120.048378","article-title":"Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and human","volume":"142","author":"Pan","year":"2020","journal-title":"Circulation"},{"key":"B243","doi-asserted-by":"publisher","first-page":"e152391","DOI":"10.1172\/JCI152391","article-title":"Cyclooxygenase-2 in adipose tissue macrophages limits adipose tissue dysfunction in obese mice","volume":"132","author":"Pan","year":"2022","journal-title":"J. Clin. Invest"},{"key":"B244","doi-asserted-by":"publisher","first-page":"G483","DOI":"10.1152\/ajpgi.00213.2017","article-title":"CC chemokine receptor 2 promotes recruitment of myeloid cells associated with insulin resistance in nonalcoholic fatty liver disease","volume":"314","author":"Parker","year":"2018","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"B245","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1053\/j.gastro.2012.07.097","article-title":"Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection","volume":"143","author":"Patin","year":"2012","journal-title":"Gastroenterology"},{"key":"B246","article-title":"Trem2 promotes foamy macrophage lipid uptake and survival in atherosclerosis","author":"Patterson","year":"2022","journal-title":"bioRxiv"},{"key":"B247","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1016\/j.tips.2018.03.001","article-title":"Macrophage-targeted therapeutics for metabolic disease","volume":"39","author":"Peterson","year":"2018","journal-title":"Trends Pharmacol. Sci."},{"key":"B248","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.jhep.2015.10.016","article-title":"MERTK rs4374383 polymorphism affects the severity of fibrosis in non-alcoholic fatty liver disease","volume":"64","author":"Petta","year":"2016","journal-title":"J. Hepatol."},{"key":"B249","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1136\/gutjnl-2014-306996","article-title":"Circulating microRNA signature in non-alcoholic fatty liver disease: From serum non-coding RNAs to liver histology and disease pathogenesis","volume":"64","author":"Pirola","year":"2015","journal-title":"Gut"},{"key":"B250","doi-asserted-by":"crossref","first-page":"e984","DOI":"10.1161\/CIR.0000000000000973","article-title":"American heart association council on Council on, Prevention, and C. Stroke, Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association","volume":"143","author":"Powell-Wiley","year":"2021","journal-title":"Circulation"},{"key":"B251","doi-asserted-by":"publisher","first-page":"3358","DOI":"10.1073\/pnas.061607398","article-title":"Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low-density lipoprotein receptor knockout mice","volume":"98","author":"Pratico","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B252","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1016\/j.immuni.2018.07.015","article-title":"Regulatory T cells promote macrophage efferocytosis during inflammation resolution","volume":"49","author":"Proto","year":"2018","journal-title":"Immunity"},{"key":"B253","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1016\/j.bbadis.2016.04.017","article-title":"Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease","volume":"1863","author":"Pugazhenthi","year":"2017","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"B254","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1002\/hep.21763","article-title":"A lipidomic analysis of nonalcoholic fatty liver disease","volume":"46","author":"Puri","year":"2007","journal-title":"Hepatology"},{"key":"B255","doi-asserted-by":"publisher","first-page":"8161","DOI":"10.1073\/pnas.0602414103","article-title":"Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability","volume":"103","author":"Qiu","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B256","doi-asserted-by":"publisher","first-page":"2904","DOI":"10.1172\/JCI75005","article-title":"Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression","volume":"127","author":"Rahman","year":"2017","journal-title":"J. Clin. Invest"},{"key":"B257","doi-asserted-by":"publisher","first-page":"2707","DOI":"10.1161\/ATVBAHA.111.232066","article-title":"MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1","volume":"31","author":"Ramirez","year":"2011","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B258","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1161\/CIRCRESAHA.112.300626","article-title":"Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144","volume":"112","author":"Ramirez","year":"2013","journal-title":"Circ. Res."},{"key":"B259","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1038\/nm.3467","article-title":"Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity","volume":"20","author":"Ramkhelawon","year":"2014","journal-title":"Nat. Med."},{"key":"B260","doi-asserted-by":"publisher","first-page":"e8707","DOI":"10.1136\/bmj.e8707","article-title":"Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: Evaluation of recovered data from the sydney diet heart study and updated meta-analysis","volume":"346","author":"Ramsden","year":"2013","journal-title":"BMJ"},{"key":"B261","doi-asserted-by":"publisher","first-page":"i1246","DOI":"10.1136\/bmj.i1246","article-title":"Re-Evaluation of the traditional diet-heart hypothesis: Analysis of recovered data from Minnesota coronary experiment (1968-73)","volume":"353","author":"Ramsden","year":"2016","journal-title":"BMJ"},{"key":"B262","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1002\/hep.23270","article-title":"Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: Results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial","volume":"51","author":"Ratziu","year":"2010","journal-title":"Hepatology"},{"key":"B263","doi-asserted-by":"publisher","first-page":"4922","DOI":"10.1016\/j.jmb.2020.07.006","article-title":"Novel mechanism of cholesterol transport by ABCA5 in macrophages and its role in dyslipidemia","volume":"432","author":"Ray","year":"2020","journal-title":"J. Mol. Biol."},{"key":"B264","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1038\/nature10486","article-title":"Inhibition of miR-33a\/b in non-human primates raises plasma HDL and lowers VLDL triglycerides","volume":"478","author":"Rayner","year":"2011","journal-title":"Nature"},{"key":"B265","doi-asserted-by":"publisher","first-page":"2921","DOI":"10.1172\/JCI57275","article-title":"Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis","volume":"121","author":"Rayner","year":"2011","journal-title":"J. Clin. Invest"},{"key":"B266","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1126\/science.1189862","article-title":"MiR-33 contributes to the regulation of cholesterol homeostasis","volume":"328","author":"Rayner","year":"2010","journal-title":"Science"},{"key":"B267","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20191374","article-title":"Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model","volume":"217","author":"Reed-Geaghan","year":"2020","journal-title":"J. Exp. Med."},{"key":"B268","doi-asserted-by":"publisher","first-page":"e0159524","DOI":"10.1371\/journal.pone.0159524","article-title":"Kupffer cells undergo fundamental changes during the development of experimental NASH and are critical in initiating liver damage and inflammation","volume":"11","author":"Reid","year":"2016","journal-title":"PLoS One"},{"key":"B269","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/j.immuni.2020.08.004","article-title":"Osteopontin expression identifies a subset of recruited macrophages distinct from kupffer cells in the fatty liver","volume":"53","author":"Remmerie","year":"2020","journal-title":"Immunity"},{"key":"B270","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.cellimm.2018.01.020","article-title":"Macrophages and lipid metabolism","volume":"330","author":"Remmerie","year":"2018","journal-title":"Cell Immunol."},{"key":"B271","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1056\/NEJMoa1809798","article-title":"Low-dose methotrexate for the prevention of atherosclerotic events","volume":"380","author":"Ridker","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"B272","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1056\/nejmoa1707914","article-title":"Antiinflammatory therapy with canakinumab for atherosclerotic disease","volume":"377","author":"Ridker","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"B273","doi-asserted-by":"publisher","first-page":"3499","DOI":"10.1093\/eurheartj\/ehy310","article-title":"Modulation of the interleukin-6 signalling pathway and incidence rates of atherosclerotic events and all-cause mortality: Analyses from the canakinumab anti-inflammatory thrombosis outcomes study (CANTOS)","volume":"39","author":"Ridker","year":"2018","journal-title":"Eur. Heart J."},{"key":"B274","doi-asserted-by":"publisher","first-page":"5384","DOI":"10.1096\/fj.201700394R","article-title":"The specialized proresolving lipid mediator maresin 1 protects hepatocytes from lipotoxic and hypoxia-induced endoplasmic reticulum stress","volume":"31","author":"Rius","year":"2017","journal-title":"FASEB J."},{"key":"B275","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1096\/fj.13-235614","article-title":"Resolvin D1 primes the resolution process initiated by calorie restriction in obesity-induced steatohepatitis","volume":"28","author":"Rius","year":"2014","journal-title":"FASEB J."},{"key":"B276","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1038\/nm.3258","article-title":"Local proliferation dominates lesional macrophage accumulation in atherosclerosis","volume":"19","author":"Robbins","year":"2013","journal-title":"Nat. Med."},{"key":"B277","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/nrcardio.2009.55","article-title":"Obesity, inflammation, and atherosclerosis","volume":"6","author":"Rocha","year":"2009","journal-title":"Nat. Rev. Cardiol."},{"key":"B278","doi-asserted-by":"publisher","first-page":"13531","DOI":"10.1073\/pnas.1735526100","article-title":"Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading","volume":"100","author":"Rong","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B279","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1016\/s0735-1097(03)00304-8","article-title":"Effects of MF-tricyclic, a selective cyclooxygenase-2 inhibitor, on atherosclerosis progression and susceptibility to cytomegalovirus replication in apolipoprotein-E knockout mice","volume":"41","author":"Rott","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"B280","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/j.immuni.2019.09.002","article-title":"Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain kupffer cell identity","volume":"51","author":"Sakai","year":"2019","journal-title":"Immunity"},{"key":"B281","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1053\/j.gastro.2014.04.046","article-title":"No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial","volume":"147","author":"Sanyal","year":"2014","journal-title":"Gastroenterology"},{"key":"B282","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1038\/ncpgasthep0186","article-title":"Mechanisms of disease: Adipocytokines and visceral adipose tissue--emerging role in nonalcoholic fatty liver disease","volume":"2","author":"Schaffler","year":"2005","journal-title":"Nat. Clin. Pract. Gastroenterol. Hepatol."},{"key":"B283","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1161\/01.atv.0000166517.18801.a7","article-title":"Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis","volume":"25","author":"Schrijvers","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B284","doi-asserted-by":"publisher","first-page":"20128","DOI":"10.1038\/s41598-020-75353-6","article-title":"The relationship between specialized pro-resolving lipid mediators, morbid obesity and weight loss after bariatric surgery","volume":"10","author":"Schulte","year":"2020","journal-title":"Sci. Rep."},{"key":"B285","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1126\/science.1219179","article-title":"A lineage of myeloid cells independent of Myb and hematopoietic stem cells","volume":"336","author":"Schulz","year":"2012","journal-title":"Science"},{"key":"B286","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1038\/s41575-018-0065-y","article-title":"Apoptosis and necroptosis in the liver: A matter of life and death","volume":"15","author":"Schwabe","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"B287","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1002\/hep.27289","article-title":"Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: Results from the welcome* study","volume":"60","author":"Scorletti","year":"2014","journal-title":"Hepatology"},{"key":"B288","doi-asserted-by":"publisher","first-page":"10321","DOI":"10.1038\/ncomms10321","article-title":"Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells","volume":"7","author":"Scott","year":"2016","journal-title":"Nat. Commun."},{"key":"B289","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/j.immuni.2020.04.001","article-title":"Niche-specific reprogramming of epigenetic landscapes drives myeloid cell diversity in nonalcoholic steatohepatitis","volume":"52","author":"Seidman","year":"2020","journal-title":"Immunity"},{"key":"B290","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1038\/nm.3866","article-title":"KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis","volume":"21","author":"Shankman","year":"2015","journal-title":"Nat. Med."},{"key":"B291","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1038\/s41593-020-0642-6","article-title":"Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1","volume":"23","author":"Shen","year":"2020","journal-title":"Nat. Neurosci."},{"key":"B292","doi-asserted-by":"publisher","first-page":"eabp8309","DOI":"10.1126\/scitranslmed.abp8309","article-title":"CD47-SIRP\u03b1 axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis","volume":"14","author":"Shi","year":"2022","journal-title":"Sci. Transl. Med."},{"key":"B293","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1084\/jem.20181049","article-title":"Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges","volume":"216","author":"Silva","year":"2019","journal-title":"J. Exp. Med."},{"key":"B294","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1016\/j.immuni.2022.07.004","article-title":"Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration","volume":"55","author":"Silvin","year":"2022","journal-title":"Immunity"},{"key":"B295","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.jalz.2017.06.2637","article-title":"Obesity trajectories and risk of dementia: 28 years of follow-up in the whitehall II study","volume":"14","author":"Singh-Manoux","year":"2018","journal-title":"Alzheimers Dement."},{"key":"B296","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1111\/bcpt.13190","article-title":"A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease","volume":"124","author":"Skat-Rordam","year":"2019","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"B297","doi-asserted-by":"publisher","first-page":"e0242543","DOI":"10.1371\/journal.pone.0242543","article-title":"Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators","volume":"15","author":"Sobrino","year":"2020","journal-title":"PLoS One"},{"key":"B298","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1038\/s41573-021-00198-1","article-title":"Targeting inflammation in atherosclerosis - from experimental insights to the clinic","volume":"20","author":"Soehnlein","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"B299","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1016\/j.cmet.2007.09.011","article-title":"JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity","volume":"6","author":"Solinas","year":"2007","journal-title":"Cell Metab."},{"key":"B300","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.atherosclerosis.2009.10.011","article-title":"Circulating levels and hepatic expression of molecular mediators of atherosclerosis in nonalcoholic fatty liver disease","volume":"209","author":"Sookoian","year":"2010","journal-title":"Atherosclerosis"},{"key":"B301","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1073\/pnas.242716099","article-title":"Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis","volume":"100","author":"Spanbroek","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B302","doi-asserted-by":"publisher","first-page":"1942","DOI":"10.4049\/jimmunol.1100196","article-title":"Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity","volume":"187","author":"Spite","year":"2011","journal-title":"J. Immunol."},{"key":"B303","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1476-9255-8-8","article-title":"Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice","volume":"8","author":"Stanton","year":"2011","journal-title":"J. Inflamm. (Lond)"},{"key":"B304","doi-asserted-by":"publisher","first-page":"21839","DOI":"10.1016\/s0021-9258(18)54714-1","article-title":"Transcriptional repression of the GLUT4 and C\/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha","volume":"266","author":"Stephens","year":"1991","journal-title":"J. Biol. Chem."},{"key":"B305","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1002\/hep.23337","article-title":"Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity","volume":"51","author":"Stienstra","year":"2010","journal-title":"Hepatology"},{"key":"B306","doi-asserted-by":"publisher","first-page":"e418","DOI":"10.1161\/STROKEAHA.109.576967","article-title":"Excess body weight and incidence of stroke: meta-analysis of prospective studies with 2 million participants","volume":"41","author":"Strazzullo","year":"2010","journal-title":"Stroke"},{"key":"B307","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1016\/j.metabol.2013.06.008","article-title":"Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes","volume":"62","author":"Sullivan","year":"2013","journal-title":"Metabolism"},{"key":"B308","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1016\/j.febslet.2012.03.068","article-title":"MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7","volume":"586","author":"Sun","year":"2012","journal-title":"FEBS Lett."},{"key":"B309","doi-asserted-by":"publisher","first-page":"36207","DOI":"10.1038\/srep36207","article-title":"MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes","volume":"6","author":"Suresh Babu","year":"2016","journal-title":"Sci. Rep."},{"key":"B310","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1172\/JCI29950","article-title":"Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata","volume":"117","author":"Swirski","year":"2007","journal-title":"J. Clin. Invest"},{"key":"B311","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1172\/JCI28549","article-title":"Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques","volume":"117","author":"Tacke","year":"2007","journal-title":"J. Clin. Invest"},{"key":"B312","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1194\/jlr.m035568","article-title":"Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity","volume":"54","author":"Takahashi","year":"2013","journal-title":"J. Lipid Res."},{"key":"B313","doi-asserted-by":"publisher","first-page":"44147","DOI":"10.1074\/jbc.M204810200","article-title":"Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor","volume":"277","author":"Takayama","year":"2002","journal-title":"J. Biol. Chem."},{"key":"B314","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1161\/01.RES.0000204451.88147.96","article-title":"A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling","volume":"98","author":"Takayama","year":"2006","journal-title":"Circ. Res."},{"key":"B315","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1038\/nri3793","article-title":"Cholesterol, inflammation and innate immunity","volume":"15","author":"Tall","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"B316","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.cmet.2008.03.001","article-title":"HDL, ABC transporters, and cholesterol efflux: Implications for the treatment of atherosclerosis","volume":"7","author":"Tall","year":"2008","journal-title":"Cell Metab."},{"key":"B317","doi-asserted-by":"publisher","first-page":"e105192","DOI":"10.1371\/journal.pone.0105192","article-title":"A pilot study of serum microRNAs panel as potential biomarkers for diagnosis of nonalcoholic fatty liver disease","volume":"9","author":"Tan","year":"2014","journal-title":"PLoS One"},{"key":"B318","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1097\/MCG.0b013e31815591aa","article-title":"Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis","volume":"42","author":"Tanaka","year":"2008","journal-title":"J. Clin. Gastroenterol."},{"key":"B319","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1093\/cvr\/cvq262","article-title":"Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions","volume":"89","author":"Tang","year":"2011","journal-title":"Cardiovasc Res."},{"key":"B320","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-022-01099-0","article-title":"Gas6 promotes microglia efferocytosis and suppresses inflammation through activating axl\/rac1 signaling in subarachnoid hemorrhage mice","volume":"2022","author":"Tang","year":"2022","journal-title":"Transl. Stroke Res"},{"key":"B321","doi-asserted-by":"publisher","first-page":"11896","DOI":"10.1073\/pnas.182199799","article-title":"Identification of macrophage liver X receptors as inhibitors of atherosclerosis","volume":"99","author":"Tangirala","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B322","doi-asserted-by":"publisher","first-page":"15093","DOI":"10.1073\/pnas.0704602104","article-title":"High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1","volume":"104","author":"Terasaka","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B323","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.1161\/ATVBAHA.108.175257","article-title":"Effect of macrophage overexpression of murine liver X receptor-alpha (LXR-alpha) on atherosclerosis in LDL-receptor deficient mice","volume":"28","author":"Teupser","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B324","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1002\/glia.20810","article-title":"Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke","volume":"57","author":"Thored","year":"2009","journal-title":"Glia"},{"key":"B325","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1161\/ATVBAHA.108.167197","article-title":"Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe-\/- mice","volume":"28","author":"Thorp","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B326","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1189\/jlb.0209115","article-title":"Mechanisms and consequences of efferocytosis in advanced atherosclerosis","volume":"86","author":"Thorp","year":"2009","journal-title":"J. Leukoc. Biol."},{"key":"B327","doi-asserted-by":"publisher","first-page":"3360","DOI":"10.4049\/jimmunol.1502522","article-title":"Signaling and immunoresolving actions of resolvin D1 in inflamed human visceral adipose tissue","volume":"197","author":"Titos","year":"2016","journal-title":"J. Immunol."},{"key":"B328","doi-asserted-by":"publisher","first-page":"28786","DOI":"10.1038\/srep28786","article-title":"CXCL10-Mediates macrophage, but not other innate immune cells-associated inflammation in murine nonalcoholic steatohepatitis","volume":"6","author":"Tomita","year":"2016","journal-title":"Sci. Rep."},{"key":"B329","doi-asserted-by":"publisher","first-page":"40161","DOI":"10.1074\/jbc.M112.417014","article-title":"Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-alpha production","volume":"287","author":"Tosello-Trampont","year":"2012","journal-title":"J. Biol. Chem."},{"key":"B330","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/j.immuni.2020.06.003","article-title":"Impaired kupffer cell self-renewal alters the liver response to lipid overload during non-alcoholic steatohepatitis","volume":"53","author":"Tran","year":"2020","journal-title":"Immunity"},{"key":"B331","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1002\/oby.22616","article-title":"Macrophage-derived microRNA-155 increases in obesity and influences adipocyte metabolism by targeting peroxisome proliferator-activated receptor gamma","volume":"27","author":"Tryggestad","year":"2019","journal-title":"Obes. (Silver Spring)"},{"key":"B332","doi-asserted-by":"publisher","first-page":"3520","DOI":"10.4049\/jimmunol.177.6.3520","article-title":"Cutting edge: TREM-2 attenuates macrophage activation","volume":"177","author":"Turnbull","year":"2006","journal-title":"J. Immunol."},{"key":"B333","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.cmet.2017.05.015","article-title":"Microglial inflammatory signaling orchestrates the hypothalamic immune response to dietary excess and mediates obesity susceptibility","volume":"26","author":"Valdearcos","year":"2017","journal-title":"Cell Metab."},{"key":"B334","doi-asserted-by":"publisher","first-page":"E53","DOI":"10.1161\/01.atv.20.9.e53","article-title":"Role of macrophage-derived lipoprotein lipase in lipoprotein metabolism and atherosclerosis","volume":"20","author":"Van Eck","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B335","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1038\/ni.2205","article-title":"The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques","volume":"13","author":"van Gils","year":"2012","journal-title":"Nat. Immunol."},{"key":"B336","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1038\/nm.2279","article-title":"The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance","volume":"17","author":"Vandanmagsar","year":"2011","journal-title":"Nat. Med."},{"key":"B337","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1146\/annurev.pharmtox.38.1.97","article-title":"Cyclooxygenases 1 and 2","volume":"38","author":"Vane","year":"1998","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"B338","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1161\/01.RES.0000109793.17591.4E","article-title":"Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice","volume":"94","author":"Veillard","year":"2004","journal-title":"Circ. Res."},{"key":"B339","doi-asserted-by":"publisher","first-page":"33453","DOI":"10.1038\/srep33453","article-title":"FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis","volume":"6","author":"Verbeke","year":"2016","journal-title":"Sci. Rep."},{"key":"B340","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1161\/CIRCRESAHA.116.309492","article-title":"Resolving lipid mediators maresin 1 and resolvin D2 prevent atheroprogression in mice","volume":"119","author":"Viola","year":"2016","journal-title":"Circ. Res."},{"key":"B341","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1038\/nm.3980","article-title":"Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis","volume":"21","author":"Wagschal","year":"2015","journal-title":"Nat. Med."},{"key":"B342","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1038\/nm0102-75","article-title":"Interleukin-6-deficient mice develop mature-onset obesity","volume":"8","author":"Wallenius","year":"2002","journal-title":"Nat. Med."},{"key":"B343","doi-asserted-by":"publisher","first-page":"9558","DOI":"10.1074\/jbc.270.16.9558","article-title":"Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms","volume":"270","author":"Wang","year":"1995","journal-title":"J. Biol. Chem."},{"key":"B344","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.immuni.2022.11.013","article-title":"Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development","volume":"56","author":"Wang","year":"2023","journal-title":"Immunity"},{"key":"B345","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jalz.2013.12.024","article-title":"Resolution of inflammation is altered in Alzheimer's disease","volume":"11","author":"Wang","year":"2015","journal-title":"Alzheimers Dement."},{"key":"B346","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/S0140-6736(11)60814-3","article-title":"Health and economic burden of the projected obesity trends in the USA and the UK","volume":"378","author":"Wang","year":"2011","journal-title":"Lancet"},{"key":"B347","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1161\/ATVBAHA.112.300941","article-title":"Neuroimmune guidance cue Semaphorin 3E is expressed in atherosclerotic plaques and regulates macrophage retention","volume":"33","author":"Wanschel","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B348","doi-asserted-by":"publisher","first-page":"2619","DOI":"10.1172\/jci124615","article-title":"The role of macrophages in the resolution of inflammation","volume":"129","author":"Watanabe","year":"2019","journal-title":"J. Clin. Invest"},{"key":"B349","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1161\/CIRCULATIONAHA.112.000736","article-title":"The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1-and microRNA-155-dependent pathway during atherosclerosis","volume":"127","author":"Wei","year":"2013","journal-title":"Circulation"},{"key":"B350","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1038\/s41467-018-03566-5","article-title":"Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction","volume":"9","author":"Weinhard","year":"2018","journal-title":"Nat. Commun."},{"key":"B351","doi-asserted-by":"publisher","first-page":"e190008","DOI":"10.20900\/immunometab20190008","article-title":"Single-cell RNA sequencing of visceral adipose tissue leukocytes reveals that caloric restriction following obesity promotes the accumulation of a distinct macrophage population with features of phagocytic cells","volume":"1","author":"Weinstock","year":"2019","journal-title":"Immunometabolism"},{"key":"B352","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/978-1-4939-9130-3_12","article-title":"Methods to study monocyte and macrophage trafficking in atherosclerosis progression and resolution","volume":"1951","author":"Weinstock","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"B353","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.1161\/CIRCRESAHA.120.316203","article-title":"Leukocyte heterogeneity in adipose tissue, including in obesity","volume":"126","author":"Weinstock","year":"2020","journal-title":"Circ. Res."},{"key":"B354","doi-asserted-by":"publisher","first-page":"e67932","DOI":"10.7554\/eLife.67932","article-title":"Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis","volume":"10","author":"Weinstock","year":"2021","journal-title":"Elife"},{"key":"B355","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1172\/JCI24335","article-title":"CCR2 modulates inflammatory and metabolic effects of high-fat feeding","volume":"116","author":"Weisberg","year":"2006","journal-title":"J. Clin. Invest"},{"key":"B356","doi-asserted-by":"publisher","first-page":"1796","DOI":"10.1172\/jci200319246","article-title":"Obesity is associated with macrophage accumulation in adipose tissue","volume":"112","author":"Weisberg","year":"2003","journal-title":"J. Clin. Invest"},{"key":"B357","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1111\/j.1572-0241.2007.01774.x","article-title":"Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis","volume":"103","author":"Wieckowska","year":"2008","journal-title":"Am. J. Gastroenterol."},{"key":"B358","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1038\/s41590-020-0768-4","article-title":"Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression","volume":"21","author":"Williams","year":"2020","journal-title":"Nat. Immunol."},{"key":"B359","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1161\/CIRCRESAHA.117.312513","article-title":"Atlas of the immune cell repertoire in mouse atherosclerosis defined by single-cell RNA-sequencing and mass cytometry","volume":"122","author":"Winkels","year":"2018","journal-title":"Circ. Res."},{"key":"B360","doi-asserted-by":"publisher","first-page":"1785","DOI":"10.1172\/jci115499","article-title":"Role of oxidized low-density lipoprotein in atherogenesis","volume":"88","author":"Witztum","year":"1991","journal-title":"J. Clin. Invest"},{"key":"B361","doi-asserted-by":"publisher","first-page":"9764","DOI":"10.1523\/JNEUROSCI.4790-14.2015","article-title":"miR-155 is essential for inflammation-induced hippocampal neurogenic dysfunction","volume":"35","author":"Woodbury","year":"2015","journal-title":"J. Neurosci."},{"key":"B362","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1007\/s00109-014-1170-1","article-title":"NLRP3 inflammasome activation is required for fibrosis development in NAFLD","volume":"92","author":"Wree","year":"2014","journal-title":"J. Mol. Med. Berl."},{"key":"B363","doi-asserted-by":"publisher","first-page":"617879","DOI":"10.3389\/fcell.2020.617879","article-title":"Tissue-resident macrophage development and function","volume":"8","author":"Wu","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"B364","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1172\/jci200319451","article-title":"Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance","volume":"112","author":"Xu","year":"2003","journal-title":"J. Clin. Invest"},{"key":"B365","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1007\/s00125-009-1309-8","article-title":"Inhibition of the chemokine (C-C motif) ligand 2\/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy","volume":"52","author":"Yang","year":"2009","journal-title":"Diabetologia"},{"key":"B366","doi-asserted-by":"publisher","first-page":"14430","DOI":"10.3748\/wjg.v20.i39.14430","article-title":"FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation","volume":"20","author":"Yao","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"B367","doi-asserted-by":"publisher","first-page":"631714","DOI":"10.3389\/fimmu.2021.631714","article-title":"Cellular responses to the efferocytosis of apoptotic cells","volume":"12","author":"Yin","year":"2021","journal-title":"Front. Immunol."},{"key":"B368","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/j.cmet.2020.12.019","article-title":"MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice","volume":"33","author":"Ying","year":"2021","journal-title":"Cell Metab."},{"key":"B369","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.cell.2017.08.035","article-title":"Adipose tissue macrophage-derived exosomal miRNAs can modulate in vivo and in vitro insulin sensitivity","volume":"171","author":"Ying","year":"2017","journal-title":"Cell"},{"key":"B370","doi-asserted-by":"publisher","first-page":"4149","DOI":"10.1172\/JCI81656","article-title":"MicroRNA-223 is a crucial mediator of PPAR\u03b3-regulated alternative macrophage activation","volume":"125","author":"Ying","year":"2015","journal-title":"J. Clin. Invest"},{"key":"B371","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.immuni.2012.12.001","article-title":"Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis","volume":"38","author":"Yona","year":"2013","journal-title":"Immunity"},{"key":"B372","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/j.cmet.2020.01.001","article-title":"Macrophage metabolism of apoptotic cell-derived arginine promotes continual efferocytosis and resolution of injury","volume":"31","author":"Yurdagul","year":"2020","journal-title":"Cell Metab."},{"key":"B373","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1161\/CIRCRESAHA.120.316903","article-title":"Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas","volume":"127","author":"Zernecke","year":"2020","journal-title":"Circ. Res."},{"key":"B374","doi-asserted-by":"publisher","first-page":"e55676","DOI":"10.7554\/eLife.55676","article-title":"MicroRNAs of the miR-17\u223c9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression","volume":"9","author":"Zhang","year":"2020","journal-title":"Elife"},{"key":"B375","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.1161\/STROKEAHA.111.000504","article-title":"MiRNA-424 protects against permanent focal cerebral ischemia injury in mice involving suppressing microglia activation","volume":"44","author":"Zhao","year":"2013","journal-title":"Stroke"},{"key":"B376","doi-asserted-by":"publisher","first-page":"6425","DOI":"10.1002\/jcp.26461","article-title":"The origins and homeostasis of monocytes and tissue-resident macrophages in physiological situation","volume":"233","author":"Zhao","year":"2018","journal-title":"J. Cell Physiol."},{"key":"B377","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1038\/s41590-020-0750-1","article-title":"IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes","volume":"21","author":"Zhou","year":"2020","journal-title":"Nat. Immunol."},{"key":"B378","doi-asserted-by":"publisher","first-page":"3128053","DOI":"10.1155\/2020\/3128053","article-title":"lncRNA-SNHG14 promotes atherosclerosis by regulating ROR\u03b1 expression through sponge miR-19a-3p","volume":"2020","author":"Zhu","year":"2020","journal-title":"Comput. Math. Methods Med."},{"key":"B379","doi-asserted-by":"publisher","first-page":"2733","DOI":"10.1007\/s12035-015-9544-0","article-title":"Pro-resolving lipid mediators improve neuronal survival and increase A\u03b242 phagocytosis","volume":"53","author":"Zhu","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"B380","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.1161\/CIRCULATIONAHA.111.087817","article-title":"A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation","volume":"125","author":"Zhuang","year":"2012","journal-title":"Circulation"}],"container-title":["Frontiers in Cell and Developmental Biology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2023.1147434\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T11:53:35Z","timestamp":1678708415000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2023.1147434\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,13]]},"references-count":380,"alternative-id":["10.3389\/fcell.2023.1147434"],"URL":"https:\/\/doi.org\/10.3389\/fcell.2023.1147434","relation":{},"ISSN":["2296-634X"],"issn-type":[{"value":"2296-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,13]]},"article-number":"1147434"}}