{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:18:32Z","timestamp":1790612312438,"version":"4.1.0"},"reference-count":312,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004686","name":"Deanship of Scientific Research, King Faisal University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004686","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell Dev. Biol."],"abstract":"<jats:p>Among women, breast cancer ranks as the most prevalent form of cancer, and the presence of metastases significantly reduces prognosis and diminishes overall survival rates. Gaining insights into the biological mechanisms governing the conversion of cancer cells, their subsequent spread to other areas of the body, and the immune system\u2019s monitoring of tumor growth will contribute to the advancement of more efficient and targeted therapies. MicroRNAs (miRNAs) play a critical role in the interaction between tumor cells and immune cells, facilitating tumor cells\u2019 evasion of the immune system and promoting cancer progression. Additionally, miRNAs also influence metastasis formation, including the establishment of metastatic sites and the transformation of tumor cells into migratory phenotypes. Specifically, dysregulated expression of these genes has been associated with abnormal expression of oncogenes and tumor suppressor genes, thereby facilitating tumor development. This study aims to provide a concise overview of the significance and function of miRNAs in breast cancer, focusing on their involvement as tumor suppressors in the antitumor immune response and as oncogenes in metastasis formation. Furthermore, miRNAs hold tremendous potential as targets for gene therapy due to their ability to modulate specific pathways that can either promote or suppress carcinogenesis. This perspective highlights the latest strategies developed for miRNA-based therapies.<\/jats:p>","DOI":"10.3389\/fcell.2024.1390704","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:23:54Z","timestamp":1714004634000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":31,"title":["Mapping the function of MicroRNAs as a critical regulator of tumor-immune cell communication in breast cancer and potential treatment strategies"],"prefix":"10.3389","volume":"12","author":[{"given":"Aimi Syamima","family":"Abdul Manap","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aini Athirah","family":"Wisham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei Wen","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huda Raihanah","family":"Ahmad Najmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi Fei","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubaiyat Siddique","family":"Diba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.ncrna.2022.09.003","article-title":"Expression of MiRNA-29b and MiRNA-31 and their diagnostic and prognostic values in Egyptian females with breast cancer","volume":"7","author":"Abbas","year":"2022","journal-title":"Non-Coding RNA Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1089\/nat.2020.0871","article-title":"Efficiency and target derepression of anti-miR-92a: results of a first in human study","volume":"30","author":"Abplanalp","year":"2020","journal-title":"Nucleic Acid. Ther."},{"key":"B3","doi-asserted-by":"publisher","first-page":"7151","DOI":"10.1002\/jcb.26754","article-title":"Simultaneous downregulation of miR\u201021 and miR\u2010155 through oleuropein for breast cancer prevention and therapy","volume":"119","author":"Abtin","year":"2018","journal-title":"J. Cell Biochem."},{"key":"B4","doi-asserted-by":"publisher","first-page":"113","DOI":"10.3390\/cells9010113","article-title":"MicroRNAs: biological regulators in pathogen\u2013host interactions","volume":"9","author":"Acu\u00f1a","year":"2020","journal-title":"Cells"},{"key":"B5","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s40291-020-00447-w","article-title":"Emergence of circulating MicroRNAs in breast cancer as diagnostic and therapeutic efficacy biomarkers","volume":"24","author":"Aggarwal","year":"2020","journal-title":"Mol. Diagn Ther."},{"key":"B6","doi-asserted-by":"publisher","first-page":"6330","DOI":"10.1093\/nar\/gky262","article-title":"Eukaryotic translation initiation factor 4AII contributes to microRNA-122 regulation of hepatitis C virus replication","volume":"46","author":"Ahmed","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"B7","doi-asserted-by":"publisher","first-page":"193","DOI":"10.31557\/APJCP.2019.20.1.193","article-title":"MiR-126 modulates angiogenesis in breast cancer by targeting VEGF-A-mRNA","volume":"20","author":"Alhasan","year":"2019","journal-title":"Asian Pac J. Cancer Prev. APJCP"},{"key":"B8","article-title":"Breast cancer","volume-title":"StatPearls","author":"Alkabban","year":"2023"},{"key":"B9","doi-asserted-by":"publisher","first-page":"13046","DOI":"10.3390\/ijms241713046","article-title":"Deregulated miRNA expression in triple-negative breast cancer of ancestral genomic-characterized Latina patients","volume":"24","author":"Almohaywi","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s12195-021-00679-8","article-title":"Immune system effects on breast cancer","volume":"14","author":"Amens","year":"","journal-title":"Cell Mol. Bioeng."},{"key":"B11","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s12195-021-00679-8","article-title":"Immune system effects on breast cancer","volume":"14","author":"Amens","year":"","journal-title":"Cell Mol. Bioeng."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.31557\/APJCP.2019.20.4.1223","article-title":"Upregulation of circulating MiR-21 expression as a potential biomarker for therapeutic monitoring and clinical outcome in breast cancer","volume":"20","author":"Anwar","year":"2019","journal-title":"Asian Pac J. Cancer Prev. APJCP"},{"key":"B13","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.breast.2022.08.010","article-title":"Current and future burden of breast cancer: global statistics for 2020 and 2040","volume":"66","author":"Arnold","year":"2022","journal-title":"Breast"},{"key":"B14","doi-asserted-by":"publisher","first-page":"651","DOI":"10.3390\/biomedicines10030651","article-title":"Breast cancer subtype-specific mirnas: networks, impacts, and the potential for intervention","volume":"10","author":"Arun","year":"2022","journal-title":"Biomedicines"},{"key":"B15","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.lfs.2019.01.005","article-title":"Phenotypical and functional evaluation of dendritic cells after exosomal delivery of miRNA-155","volume":"219","author":"Asadirad","year":"2019","journal-title":"Life Sci."},{"key":"B16","doi-asserted-by":"publisher","first-page":"E1695","DOI":"10.1073\/pnas.1201516109","article-title":"Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma","volume":"109","author":"Babar","year":"2012","journal-title":"Proc. Natl. Acad. Sci."},{"key":"B17","doi-asserted-by":"publisher","first-page":"19480","DOI":"10.1002\/jcp.28742","article-title":"The role of inflammation and its related microRNAs in breast cancer: a narrative review","volume":"234","author":"Bahiraee","year":"2019","journal-title":"J. Cell Physiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.colsurfb.2018.12.006","article-title":"A novel MUC1 aptamer-modified PLGA-epirubicin-P\u03b2AE-antimir-21 nanocomplex platform for targeted co-delivery of anticancer agents in vitro and in vivo","volume":"175","author":"Bahreyni","year":"2019","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"B19","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1186\/s43141-021-00174-7","article-title":"Impact of circulating miRNA-373 on breast cancer diagnosis through targeting VEGF and cyclin D1 genes","volume":"19","author":"Bakr","year":"2021","journal-title":"J. Genet. Eng. Biotechnol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"174","DOI":"10.3389\/fgene.2018.00174","article-title":"Screen for MicroRNA and drug interactions in breast cancer cell lines points to miR-126 as a modulator of CDK4\/6 and PIK3CA inhibitors","volume":"9","author":"Baldassari","year":"2018","journal-title":"Front. Genet."},{"key":"B21","doi-asserted-by":"publisher","first-page":"e369","DOI":"10.37029\/jcas.v7i1.369","article-title":"Expression of B-cell lymphoma 2 in breast cancer","volume":"7","author":"Bashir","year":"2021","journal-title":"J. Cancer Allied Spec."},{"key":"B22","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.omtn.2020.03.003","article-title":"The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics","volume":"20","author":"Bautista-S\u00e1nchez","year":"","journal-title":"Mol. Ther-Nucleic Acids"},{"key":"B23","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.omtn.2020.03.003","article-title":"The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics","volume":"20","author":"Bautista-S\u00e1nchez","year":"","journal-title":"Mol. Ther. - Nucleic Acids"},{"key":"B24","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1038\/s41467-020-15574-5","article-title":"Re-definition of claudin-low as a breast cancer phenotype","volume":"11","author":"Bergholtz","year":"2020","journal-title":"Nat. Commun."},{"key":"B25","doi-asserted-by":"publisher","first-page":"606","DOI":"10.3390\/biomedicines9060606","article-title":"let-7 microRNAs: their role in cerebral and cardiovascular diseases, inflammation, cancer, and their regulation","volume":"9","author":"Bernstein","year":"2021","journal-title":"Biomedicines"},{"key":"B26","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1200\/GO.20.00033","article-title":"Overview of breast cancer and implications of overtreatment of early-stage breast cancer: an Indian perspective","volume":"6","author":"Bhattacharyya","year":"2020","journal-title":"JCO Glob. Oncol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.semcdb.2017.08.016","article-title":"Protein coding genes as hosts for noncoding RNA expression","volume":"75","author":"Boivin","year":"2018","journal-title":"Semin. Cell Dev. Biol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"e2973","DOI":"10.1038\/cddis.2017.364","article-title":"MicroRNA-519a-3p mediates apoptosis resistance in breast cancer cells and their escape from recognition by natural killer cells","volume":"8","author":"Breunig","year":"2017","journal-title":"Cell Death Dis."},{"key":"B29","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1172\/JCI65871","article-title":"MicroRNA-374a activates Wnt\/\u03b2-catenin signaling to promote breast cancer metastasis","volume":"123","author":"Cai","year":"2013","journal-title":"J. Clin. Invest."},{"key":"B30","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s12943-017-0746-0","article-title":"microRNA-124 inhibits bone metastasis of breast cancer by repressing Interleukin-11","volume":"17","author":"Cai","year":"2018","journal-title":"Mol. Cancer"},{"key":"B31","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/1476-4598-13-28","article-title":"Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia","volume":"13","author":"Camps","year":"2014","journal-title":"Mol. Cancer"},{"key":"B32","doi-asserted-by":"publisher","first-page":"293","DOI":"10.20892\/j.issn.2095-3941.2019.0465","article-title":"Triple negative breast cancer: special histological types and emerging therapeutic methods","volume":"17","author":"Cao","year":"2020","journal-title":"Cancer Biol. Med."},{"key":"B33","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1097\/CM9.0000000000001474","article-title":"Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020","volume":"134","author":"Cao","year":"2021","journal-title":"Chin. Med. J. Engl."},{"key":"B34","doi-asserted-by":"publisher","first-page":"5874","DOI":"10.3390\/cancers13235874","article-title":"The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers","volume":"13","author":"Cavallari","year":"2021","journal-title":"Cancers"},{"key":"B35","unstructured":"What are the risk factors for breast cancer?2023"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.3390\/genes14071375","article-title":"miRNAs: potential as biomarkers and therapeutic targets for cancer","volume":"14","author":"Chakrabortty","year":"2023","journal-title":"Genes (Basel)"},{"key":"B37","doi-asserted-by":"publisher","first-page":"825484","DOI":"10.3389\/fonc.2022.825484","article-title":"Systemic deficiency of PTEN accelerates breast cancer growth and metastasis","volume":"12","author":"Chen","year":"2022","journal-title":"Front. Oncol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.imlet.2020.05.003","article-title":"miR-155 indicates the fate of CD4+ T cells","volume":"224","author":"Chen","year":"2020","journal-title":"Immunol. Lett."},{"key":"B39","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1038\/bjc.2017.150","article-title":"MicroRNA-211-5p suppresses tumour cell proliferation, invasion, migration and metastasis in triple-negative breast cancer by directly targeting SETBP1","volume":"117","author":"Chen","year":"","journal-title":"Br. J. Cancer"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.2147\/OTT.S118366","article-title":"MicroRNA 543 suppresses breast cancer cell proliferation, blocks cell cycle and induces cell apoptosis via direct targeting of ERK\/MAPK","volume":"10","author":"Chen","year":"","journal-title":"OncoTargets Ther."},{"key":"B41","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1038\/s41698-018-0047-0","article-title":"Organotropism: new insights into molecular mechanisms of breast cancer metastasis","volume":"2","author":"Chen","year":"2018","journal-title":"NPJ Precis. Oncol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1186\/s12885-015-1303-0","article-title":"STAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells","volume":"15","author":"Cheng","year":"2015","journal-title":"BMC Cancer"},{"key":"B43","doi-asserted-by":"publisher","first-page":"31944","DOI":"10.18632\/oncotarget.5128","article-title":"E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a\/16 promoter","volume":"6","author":"Chu","year":"2015","journal-title":"Oncotarget"},{"key":"B44","doi-asserted-by":"publisher","first-page":"3769","DOI":"10.1158\/1078-0432.CCR-16-2814","article-title":"An integrated approach identifies mediators of local recurrence in head and neck squamous carcinoma","volume":"23","author":"Citron","year":"2017","journal-title":"Clin. Cancer Res."},{"key":"B45","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1093\/jbi\/wbaa110","article-title":"Molecular subtypes of breast cancer: a review for breast radiologists","volume":"3","author":"Conant","year":"2021","journal-title":"J. Breast Imaging"},{"key":"B46","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1002\/gcc.22725","article-title":"Role of miRNAs in immune responses and immunotherapy in cancer","volume":"58","author":"Cortez","year":"2019","journal-title":"Genes Chromosom. Cancer"},{"key":"B47","doi-asserted-by":"publisher","first-page":"3446","DOI":"10.1021\/jacs.6b11273","article-title":"Small molecule inhibition of microRNA-210 reprograms an oncogenic hypoxic circuit","volume":"139","author":"Costales","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1980","DOI":"10.1002\/1873-3468.13067","article-title":"Regulation of primary micro RNA processing","volume":"592","author":"Creugny","year":"2018","journal-title":"FEBS Lett."},{"key":"B49","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1038\/s41375-018-0305-8","article-title":"Blood and skin-derived Sezary cells: differences in proliferation-index, activation of PI3K\/AKT\/mTORC1 pathway and its prognostic relevance","volume":"33","author":"Cristofoletti","year":"2019","journal-title":"Leukemia"},{"key":"B50","doi-asserted-by":"publisher","first-page":"7821","DOI":"10.1021\/acsami.7b19183","article-title":"Enhanced chemotherapeutic efficacy of paclitaxel nanoparticles co-delivered with microRNA-7 by inhibiting paclitaxel-induced EGFR\/ERK pathway activation for ovarian cancer therapy","volume":"10","author":"Cui","year":"2018","journal-title":"ACS Appl. Mater Interfaces"},{"key":"B51","doi-asserted-by":"publisher","first-page":"888","DOI":"10.3390\/cancers13040888","article-title":"miR-21 plays a dual role in tumor formation and cytotoxic response in breast tumors","volume":"13","author":"Dan","year":"2021","journal-title":"Cancers"},{"key":"B52","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.tig.2017.01.003","article-title":"Biogenesis and function of ago-associated RNAs","volume":"33","author":"Daugaard","year":"2017","journal-title":"Trends Genet."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.3390\/nu11071514","article-title":"Nutrition and breast cancer: a literature review on prevention, treatment and recurrence","volume":"11","author":"De Cicco","year":"2019","journal-title":"Nutrients"},{"key":"B54","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1148\/rg.2019180181","article-title":"Primary osteosarcoma of the breast","volume":"39","author":"Dekkers","year":"2019","journal-title":"RadioGraphics"},{"key":"B55","doi-asserted-by":"publisher","first-page":"4333","DOI":"10.1016\/j.biomaterials.2014.02.006","article-title":"Hyaluronic acid-chitosan nanoparticles for co-delivery of MiR-34a and doxorubicin in therapy against triple negative breast cancer","volume":"35","author":"Deng","year":"2014","journal-title":"Biomaterials"},{"key":"B56","doi-asserted-by":"publisher","first-page":"2080","DOI":"10.1021\/mp500852s","article-title":"Formulation of anti-miR-21 and 4-hydroxytamoxifen co-loaded biodegradable polymer nanoparticles and their antiproliferative effect on breast cancer cells","volume":"12","author":"Devulapally","year":"2015","journal-title":"Mol. Pharm."},{"key":"B57","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/j.tig.2022.02.006","article-title":"Emerging concepts of miRNA therapeutics: from cells to clinic","volume":"38","author":"Diener","year":"2022","journal-title":"Trends Genet."},{"key":"B58","doi-asserted-by":"publisher","first-page":"4145","DOI":"10.1158\/0008-5472.CAN-13-2038","article-title":"miR-155 drives telomere fragility in human breast cancer by targeting TRF1","volume":"74","author":"Dinami","year":"2014","journal-title":"Cancer Res."},{"key":"B59","doi-asserted-by":"publisher","first-page":"3241","DOI":"10.3892\/ol.2019.10001","article-title":"miR-7-5p regulates the proliferation and migration of colorectal cancer cells by negatively regulating the expression of Kr\u00fcppel-like factor 4","volume":"17","author":"Dong","year":"2019","journal-title":"Oncol. Lett."},{"key":"B60","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/s11010-017-3139-1","article-title":"MicroRNA-335 suppresses the proliferation, migration, and invasion of breast cancer cells by targeting EphA4","volume":"439","author":"Dong","year":"2018","journal-title":"Mol. Cell Biochem."},{"key":"B61","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/s42255-020-00317-z","article-title":"Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism","volume":"3","author":"Elia","year":"2021","journal-title":"Nat. Metab."},{"key":"B62","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s13046-015-0216-8","article-title":"Dual loading miR-218 mimics and Temozolomide using AuCOOH@FA-CS drug delivery system: promising targeted anti-tumor drug delivery system with sequential release functions","volume":"34","author":"Fan","year":"2015","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"B63","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1097\/MOH.0000000000000424","article-title":"MicroRNAs in endothelial cell homeostasis and vascular disease","volume":"25","author":"Fern\u00e1ndez-Hernando","year":"2018","journal-title":"Curr. Opin. Hematol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1038\/ncb3094","article-title":"Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis","volume":"17","author":"Fong","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1852","DOI":"10.3390\/cancers12071852","article-title":"A comprehensive review of cancer MicroRNA therapeutic delivery strategies","volume":"12","author":"Forterre","year":"2020","journal-title":"Cancers"},{"key":"B66","doi-asserted-by":"publisher","first-page":"2511","DOI":"10.1200\/JCO.2018.36.15_suppl.2511","article-title":"Ph 1 study of MRG-106, an inhibitor of miR-155, in CTCL","volume":"36","author":"Foss","year":"2018","journal-title":"J. Clin. Oncol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"e1701","DOI":"10.1002\/wrna.1701","article-title":"Regulation and different functions of the animal microRNA\u2010induced silencing complex","volume":"13","author":"Fr\u00e9d\u00e9rick","year":"2022","journal-title":"Wiley Interdiscip. Rev. RNA"},{"key":"B68","doi-asserted-by":"publisher","first-page":"104119","DOI":"10.1016\/j.cellimm.2020.104119","article-title":"The roles of tumor-associated macrophages in tumor angiogenesis and metastasis","volume":"353","author":"Fu","year":"2020","journal-title":"Cell Immunol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1691\/ph.2017.7600","article-title":"MicroRNA-146 regulates the inflammatory cytokines expression in vascular endothelial cells during sepsis","volume":"72","author":"Gao","year":"2017","journal-title":"Pharm- Int. J. Pharm. Sci."},{"key":"B70","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1093\/nar\/gkt852","article-title":"Miravirsen (SPC3649) can inhibit the biogenesis of miR-122","volume":"42","author":"Gebert","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"B71","doi-asserted-by":"publisher","first-page":"768949","DOI":"10.3389\/fonc.2021.768949","article-title":"Contribution of miRNAs in the pathogenesis of breast cancer","volume":"11","author":"Ghafouri-Fard","year":"2021","journal-title":"Front. Oncol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s12943-019-1029-8","article-title":"The role of necroptosis in cancer biology and therapy","volume":"18","author":"Gong","year":"2019","journal-title":"Mol. Cancer"},{"key":"B73","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1007\/s12016-016-8550-y","article-title":"The role of STAT signaling pathways in the pathogenesis of systemic lupus erythematosus","volume":"52","author":"Goropev\u0161ek","year":"2017","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"5834","DOI":"10.3390\/ijms21165834","article-title":"Prognostic and clinicopathological significance of MiR-155 in breast cancer: a systematic review","volume":"21","author":"Grimaldi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"B75","doi-asserted-by":"publisher","first-page":"668464","DOI":"10.3389\/fonc.2021.668464","article-title":"miRNA-based therapeutics in breast cancer: a systematic review","volume":"11","author":"Grimaldi","year":"2021","journal-title":"Front. Oncol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"7112","DOI":"10.3390\/ijms16047112","article-title":"MicroRNA-16 modulates HuR regulation of cyclin E1 in breast cancer cells","volume":"16","author":"Guo","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"B77","doi-asserted-by":"publisher","first-page":"8859","DOI":"10.1038\/s41598-018-27184-9","article-title":"Interleukin-6\/STAT3 signalling regulates adipocyte induced epithelial-mesenchymal transition in breast cancer cells","volume":"8","author":"Gyamfi","year":"2018","journal-title":"Sci. Rep."},{"key":"B78","doi-asserted-by":"crossref","first-page":"313","DOI":"10.15586\/codon.pkd.2015.ch13","volume-title":"MicroRNAs and polycystic kidney disease","author":"Hajarnis","year":"2015"},{"key":"B79","doi-asserted-by":"publisher","first-page":"e3045","DOI":"10.1038\/cddis.2017.440","article-title":"Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers","volume":"8","author":"Hamam","year":"2017","journal-title":"Cell Death Dis."},{"key":"B80","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1186\/s13058-016-0753-x","article-title":"Plasma exosome microRNAs are indicative of breast cancer","volume":"18","author":"Hannafon","year":"2016","journal-title":"Breast Cancer Res."},{"key":"B81","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.semcdb.2019.10.004","article-title":"Impact of the actin cytoskeleton on cell development and function mediated via tropomyosin isoforms","volume":"102","author":"Hardeman","year":"2020","journal-title":"Semin. Cell Dev. Biol."},{"key":"B82","doi-asserted-by":"publisher","first-page":"106568","DOI":"10.1016\/j.phrs.2022.106568","article-title":"Pre-clinical and clinical importance of miR-21 in human cancers: tumorigenesis, therapy response, delivery approaches and targeting agents","volume":"187","author":"Hashemi","year":"2023","journal-title":"Pharmacol. Res."},{"key":"B83","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1186\/s13104-019-4653-x","article-title":"Ki67 index in intrinsic breast cancer subtypes and its association with prognostic parameters","volume":"12","author":"Hashmi","year":"2019","journal-title":"BMC Res. Notes"},{"key":"B84","doi-asserted-by":"publisher","first-page":"dmm047662","DOI":"10.1242\/dmm.047662","article-title":"miRNA interplay: mechanisms and consequences in cancer","volume":"14","author":"Hill","year":"2021","journal-title":"Dis. Model Mech."},{"key":"B85","doi-asserted-by":"publisher","first-page":"1520","DOI":"10.1158\/0008-5472.CAN-18-0891","article-title":"Tumor suppressor miRNA-204-5p regulates growth, metastasis, and immune microenvironment remodeling in breast cancer","volume":"79","author":"Hong","year":"2019","journal-title":"Cancer Res."},{"key":"B86","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.12659\/msm.896551","article-title":"MicroRNA-200b impacts breast cancer cell migration and invasion by regulating Ezrin-Radixin-Moesin","volume":"22","author":"Hong","year":"2016","journal-title":"Med. Sci. Monit. Int. Med. J. Exp. Clin. Res."},{"key":"B87","doi-asserted-by":"publisher","first-page":"110804","DOI":"10.1016\/j.diabres.2023.110804","article-title":"Understanding the lncRNA\/miRNA-NF\u03baB regulatory network in diabetes mellitus: from function to clinical translation","volume":"202","author":"Hoorzad","year":"2023","journal-title":"Diabetes Res. Clin. Pract."},{"key":"B88","doi-asserted-by":"publisher","first-page":"1997","DOI":"10.3892\/ijo.2016.3405","article-title":"miR-135b, upregulated in breast cancer, promotes cell growth and disrupts the cell cycle by regulating LATS2","volume":"48","author":"Hua","year":"2016","journal-title":"Int. J. Oncol."},{"key":"B89","doi-asserted-by":"publisher","first-page":"6073","DOI":"10.1158\/0008-5472.CAN-18-0136","article-title":"HER2\/EGFR\u2013AKT signaling switches TGF\u03b2 from inhibiting cell proliferation to promoting cell migration in breast cancer","volume":"78","author":"Huang","year":"","journal-title":"Cancer Res."},{"key":"B90","doi-asserted-by":"publisher","first-page":"2621","DOI":"10.3892\/ol.2020.11360","article-title":"Maspin inhibits MCF-7 cell invasion and proliferation by downregulating miR-21 and increasing the expression of its target genes","volume":"19","author":"Huang","year":"2020","journal-title":"Oncol. Lett."},{"key":"B91","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.1039\/c8tb00224j","article-title":"Triple therapy of hepatocellular carcinoma with microRNA-122 and doxorubicin co-loaded functionalized gold nanocages","volume":"6","author":"Huang","year":"","journal-title":"J. Mat. Chem. B"},{"key":"B92","doi-asserted-by":"publisher","first-page":"2615","DOI":"10.3892\/etm.2018.6504","article-title":"Tumor suppressor function of miR-483-3p on breast cancer via targeting of the cyclin E1 gene","volume":"16","author":"Huang","year":"2018","journal-title":"Exp. Ther. Med."},{"key":"B93","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1002\/kjm2.12085","article-title":"MicroRNA\u201026a\u20105p inhibits breast cancer cell growth by suppressing RNF6 expression","volume":"35","author":"Huang","year":"2019","journal-title":"Kaohsiung J. Med. Sci."},{"key":"B94","doi-asserted-by":"publisher","first-page":"764025","DOI":"10.3389\/fmolb.2021.764025","article-title":"MicroRNAs: important players in breast cancer angiogenesis and therapeutic targets","volume":"8","author":"Hussen","year":"2021","journal-title":"Front. Mol. Biosci."},{"key":"B95","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s12964-022-01019-7","article-title":"The dual role of microRNA (miR)-20b in cancers: friend or foe?","volume":"21","author":"Ilhan","year":"2023","journal-title":"Cell Commun. Signal"},{"key":"B96","doi-asserted-by":"publisher","first-page":"S63","DOI":"10.1016\/S0960-9776(11)70297-1","article-title":"Breast cancer and microRNAs: therapeutic impact","volume":"20","author":"Iorio","year":"2011","journal-title":"Breast"},{"key":"B97","doi-asserted-by":"publisher","first-page":"107","DOI":"10.12701\/yujm.2020.00836","article-title":"The role of microRNAs in cell death pathways","volume":"38","author":"Jang","year":"2021","journal-title":"Yeungnam Univ. J. Med."},{"key":"B98","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1056\/NEJMoa1209026","article-title":"Treatment of HCV infection by targeting microRNA","volume":"368","author":"Janssen","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"B99","doi-asserted-by":"publisher","first-page":"108154","DOI":"10.1016\/j.abb.2019.108154","article-title":"Tanshinone IIA attenuates high glucose induced human VSMC proliferation and migration through miR-21-5p-mediated tropomyosin 1 downregulation","volume":"677","author":"Jia","year":"2019","journal-title":"Arch. Biochem. Biophys."},{"key":"B100","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.3892\/or.2015.4502","article-title":"MicroRNA-148a inhibits breast cancer migration and invasion by directly targeting WNT-1","volume":"35","author":"Jiang","year":"2016","journal-title":"Oncol. Rep."},{"key":"B101","doi-asserted-by":"publisher","first-page":"32769","DOI":"10.18632\/oncotarget.15680","article-title":"microRNA-200c\/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival","volume":"8","author":"Jin","year":"2017","journal-title":"Oncotarget"},{"key":"B102","doi-asserted-by":"publisher","first-page":"5881","DOI":"10.3390\/ijms23115881","article-title":"Potential of the miR-200 family as a target for developing anti-cancer therapeutics","volume":"23","author":"Jo","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B103","doi-asserted-by":"publisher","first-page":"525","DOI":"10.3390\/cells12040525","article-title":"Potential miRNA use as a biomarker: from breast cancer diagnosis to metastasis","volume":"12","author":"Jordan-Alejandre","year":"2023","journal-title":"Cells"},{"key":"B104","doi-asserted-by":"publisher","first-page":"e1903296","DOI":"10.1002\/smll.201903296","article-title":"pH-Responsive PEG-shedding and targeting peptide-modified nanoparticles for dual-delivery of irinotecan and microRNA to enhance tumor-specific therapy","volume":"15","author":"Juang","year":"2019","journal-title":"Small"},{"key":"B105","doi-asserted-by":"publisher","first-page":"11584","DOI":"10.1038\/s41598-018-29917-2","article-title":"MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer","volume":"8","author":"Kahraman","year":"2018","journal-title":"Sci. Rep."},{"key":"B106","doi-asserted-by":"publisher","first-page":"5414","DOI":"10.3390\/cancers14215414","article-title":"The role of miR-155 in antitumor immunity","volume":"14","author":"Kalkusova","year":"2022","journal-title":"Cancers"},{"key":"B107","doi-asserted-by":"publisher","first-page":"113442","DOI":"10.1016\/j.yexcr.2022.113442","article-title":"Locked nucleic acid (LNA): a modern approach to cancer diagnosis and treatment","volume":"423","author":"Kamali","year":"2022","journal-title":"Exp. Cell Res."},{"key":"B108","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s11658-022-00344-6","article-title":"The role of epigenetic modifications in drug resistance and treatment of breast cancer","volume":"27","author":"Karami","year":"","journal-title":"Cell Mol. Biol. Lett."},{"key":"B109","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/s11658-022-00344-6","article-title":"The role of epigenetic modifications in drug resistance and treatment of breast cancer","volume":"27","author":"Karami","year":"","journal-title":"Cell Mol. Biol. Lett."},{"key":"B110","doi-asserted-by":"publisher","first-page":"e9605439","DOI":"10.1155\/2022\/9605439","article-title":"Global increase in breast cancer incidence: risk factors and preventive measures","volume":"2022","author":"Kashyap","year":"2022","journal-title":"Biomed. Res. Int."},{"key":"B111","article-title":"Necrosis","volume-title":"StatPearls","author":"Khalid","year":"2023"},{"key":"B112","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3390\/diagnostics11010107","article-title":"Identification of MicroRNAs as diagnostic biomarkers for breast cancer based on the cancer genome atlas","volume":"11","author":"Kim","year":"2021","journal-title":"Diagnostics"},{"key":"B113","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1038\/onc.2012.636","article-title":"Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer","volume":"33","author":"Kong","year":"2014","journal-title":"Oncogene"},{"key":"B114","doi-asserted-by":"publisher","first-page":"e2415489","DOI":"10.1155\/2018\/2415489","article-title":"The Notch pathway in breast cancer progression","volume":"2018","author":"Kontomanolis","year":"2018","journal-title":"Sci. World J."},{"key":"B115","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1080\/03639045.2017.1391835","article-title":"Development and characterization of cationic solid lipid nanoparticles for co-delivery of pemetrexed and miR-21 antisense oligonucleotide to glioblastoma cells","volume":"44","author":"K\u00fc\u00e7\u00fckt\u00fcrkmen","year":"2018","journal-title":"Drug Dev. Ind. Pharm."},{"key":"B116","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1080\/03639045.2016.1200069","article-title":"Co-delivery of pemetrexed and miR-21 antisense oligonucleotide by lipid-polymer hybrid nanoparticles and effects on glioblastoma cells","volume":"43","author":"K\u00fc\u00e7\u00fckt\u00fcrkmen","year":"2017","journal-title":"Drug Dev. Ind. Pharm."},{"key":"B117","doi-asserted-by":"publisher","first-page":"e64268","DOI":"10.1371\/journal.pone.0064268","article-title":"Classifications within molecular subtypes enables identification of BRCA1\/BRCA2 mutation carriers by RNA tumor profiling","volume":"8","author":"Larsen","year":"2013","journal-title":"PloS One"},{"key":"B118","doi-asserted-by":"publisher","first-page":"561","DOI":"10.3390\/cells9030561","article-title":"Myeloid-derived suppressor cells as a therapeutic target for cancer","volume":"9","author":"Law","year":"2020","journal-title":"Cells"},{"key":"B119","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1051\/bmdcn\/2019090318","article-title":"Awareness on breast cancer screening in Malaysia: a cross sectional study","volume":"9","author":"Lee","year":"2019","journal-title":"BioMedicine"},{"key":"B120","doi-asserted-by":"publisher","first-page":"3702","DOI":"10.1172\/JCI94012","article-title":"miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity","volume":"127","author":"Li","year":"","journal-title":"J. Clin. Invest."},{"key":"B121","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/s41419-023-05841-w","article-title":"RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer","volume":"14","author":"Li","year":"2023","journal-title":"Cell Death Dis."},{"key":"B122","doi-asserted-by":"publisher","first-page":"7481","DOI":"10.1007\/s13277-015-4623-4","article-title":"Tumor-suppressive microRNA-34a inhibits breast cancer cell migration and invasion via targeting oncogenic TPD52","volume":"37","author":"Li","year":"","journal-title":"Tumor Biol."},{"key":"B123","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1377\/hlthaff.2020.01714","article-title":"Spending on Targeted Therapies Reduced Mortality in Patients with Advanced-Stage Breast Cancer: study examines spending on targeted therapies for patients with advanced-stage breast cancer and the impact on mortality","volume":"40","author":"Li","year":"","journal-title":"Health Aff. (Millwood)"},{"key":"B124","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1007\/s12094-020-02501-9","article-title":"Evaluation of color Doppler ultrasound combined with plasma miR-21 and miR-27a in the diagnosis of breast cancer","volume":"23","author":"Li","year":"","journal-title":"Clin. Transl. Oncol."},{"key":"B125","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/j.actbio.2018.05.049","article-title":"A dual-targeting reconstituted high density lipoprotein leveraging the synergy of sorafenib and antimiRNA21 for enhanced hepatocellular carcinoma therapy","volume":"75","author":"Li","year":"2018","journal-title":"Acta Biomater."},{"key":"B126","doi-asserted-by":"publisher","first-page":"7006","DOI":"10.1002\/cam4.2572","article-title":"A five\u2010miRNA panel in plasma was identified for breast cancer diagnosis","volume":"8","author":"Li","year":"","journal-title":"Cancer Med."},{"key":"B127","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.yexcr.2016.01.004","article-title":"Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis","volume":"340","author":"Li","year":"","journal-title":"Exp. Cell Res."},{"key":"B128","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1186\/s12935-022-02536-8","article-title":"LRP11-AS1 promotes the proliferation and migration of triple negative breast cancer cells via the miR-149-3p\/NRP2 axis","volume":"22","author":"Li","year":"2022","journal-title":"Cancer Cell Int."},{"key":"B129","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1097\/CAD.0000000000000498","article-title":"MicroRNA-148a promotes apoptosis and suppresses growth of breast cancer cells by targeting B-cell lymphoma 2","volume":"28","author":"Li","year":"","journal-title":"Anticancer Drugs"},{"key":"B130","doi-asserted-by":"publisher","first-page":"455941","DOI":"10.3389\/fgene.2019.01278","article-title":"Targeted inhibition of miR-221\/222 promotes cell sensitivity to cisplatin in triple-negative breast cancer MDA-MB-231 cells","volume":"10","author":"Li","year":"","journal-title":"Front. Genet."},{"key":"B131","doi-asserted-by":"publisher","first-page":"22343","DOI":"10.1002\/jcp.28800","article-title":"HOXC13\u2010AS promotes breast cancer cell growth through regulating miR\u2010497\u20105p\/PTEN axis","volume":"234","author":"Li","year":"","journal-title":"J. Cell Physiol."},{"key":"B132","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.canlet.2017.03.032","article-title":"MiRNA-29b suppresses tumor growth through simultaneously inhibiting angiogenesis and tumorigenesis by targeting Akt3","volume":"397","author":"Li","year":"","journal-title":"Cancer Lett."},{"key":"B133","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1111\/cas.13267","article-title":"Co\u2010delivery of micro RNA\u201021 antisense oligonucleotides and gemcitabine using nanomedicine for pancreatic cancer therapy","volume":"108","author":"Li","year":"","journal-title":"Cancer Sci."},{"key":"B134","doi-asserted-by":"publisher","first-page":"7132","DOI":"10.1039\/d0bm01579b","article-title":"Combinatorial miRNA-34a replenishment and irinotecan delivery via auto-fluorescent polymeric hybrid micelles for synchronous colorectal cancer theranostics","volume":"8","author":"Li","year":"","journal-title":"Biomater. Sci."},{"key":"B135","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s12951-019-0563-2","article-title":"Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer","volume":"18","author":"Liang","year":"2020","journal-title":"J. Nanobiotechnology"},{"key":"B136","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.biomaterials.2018.10.036","article-title":"Dual responsive micelles capable of modulating miRNA-34a to combat taxane resistance in prostate cancer","volume":"192","author":"Lin","year":"2019","journal-title":"Biomaterials"},{"key":"B137","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.7150\/thno.22834","article-title":"UTMD-promoted co-delivery of gemcitabine and miR-21 inhibitor by dendrimer-entrapped gold nanoparticles for pancreatic cancer therapy","volume":"8","author":"Lin","year":"2018","journal-title":"Theranostics"},{"key":"B138","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1038\/nrc3932","article-title":"MicroRNA biogenesis pathways in cancer","volume":"15","author":"Lin","year":"2015","journal-title":"Nat. Rev. Cancer"},{"key":"B139","doi-asserted-by":"publisher","first-page":"9995","DOI":"10.1038\/srep09995","article-title":"MicroRNA-33b inhibits breast cancer metastasis by targeting HMGA2, SALL4 and Twist1","volume":"5","author":"Lin","year":"2015","journal-title":"Sci. Rep."},{"key":"B140","doi-asserted-by":"publisher","first-page":"281","DOI":"10.7150\/thno.35568","article-title":"RNA nanotechnology-mediated cancer immunotherapy","volume":"10","author":"Lin","year":"2020","journal-title":"Theranostics"},{"key":"B141","doi-asserted-by":"publisher","first-page":"1763","DOI":"10.21037\/tcr.2019.08.30","article-title":"MicroRNA let-7a inhibits proliferation of breast cancer cell by downregulating USP32 expression","volume":"8","author":"Liu","year":"2019","journal-title":"Transl. Cancer Res."},{"key":"B142","doi-asserted-by":"publisher","first-page":"e181","DOI":"10.1002\/mco2.181","article-title":"Small molecule inhibitors targeting the cancers","volume":"3","author":"Liu","year":"2022","journal-title":"MedComm"},{"key":"B143","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.3892\/ijo.2018.4492","article-title":"A miR-26a\/E2F7 feedback loop contributes to tamoxifen resistance in ER-positive breast cancer","volume":"53","author":"Liu","year":"","journal-title":"Int. J. Oncol."},{"key":"B144","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1089\/dna.2016.3282","article-title":"microRNA-497 modulates breast cancer cell proliferation, invasion, and survival by targeting SMAD7","volume":"35","author":"Liu","year":"2016","journal-title":"DNA Cell Biol."},{"key":"B145","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.ejps.2018.06.009","article-title":"Platinated graphene oxide: a nanoplatform for efficient gene-chemo combination cancer therapy","volume":"121","author":"Liu","year":"","journal-title":"Eur. J. Pharm. Sci."},{"key":"B146","doi-asserted-by":"publisher","first-page":"7191","DOI":"10.1016\/j.biomaterials.2013.06.004","article-title":"Targeted delivery of miR-200c\/DOC to inhibit cancer stem cells and cancer cells by the gelatinases-stimuli nanoparticles","volume":"34","author":"Liu","year":"2013","journal-title":"Biomaterials"},{"key":"B147","doi-asserted-by":"publisher","first-page":"4940","DOI":"10.3390\/ijms20194940","article-title":"The regulatory role of MicroRNAs in breast cancer","volume":"20","author":"Loh","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"B148","doi-asserted-by":"publisher","first-page":"7208","DOI":"10.3390\/ijms24087208","article-title":"Extracellular vesicles in breast cancer: from biology and function to clinical diagnosis and therapeutic management","volume":"24","author":"Loric","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"B149","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1038\/cgt.2017.30","article-title":"MicroRNA-140-5p inhibits invasion and angiogenesis through targeting VEGF-A in breast cancer","volume":"24","author":"Lu","year":"2017","journal-title":"Cancer Gene Ther."},{"key":"B150","doi-asserted-by":"publisher","first-page":"4287","DOI":"10.3390\/cancers13174287","article-title":"Breast cancer\u2014epidemiology, risk factors, classification, prognostic markers, and current treatment strategies\u2014an updated review","volume":"13","author":"\u0141ukasiewicz","year":"","journal-title":"Cancers"},{"key":"B151","doi-asserted-by":"publisher","first-page":"4287","DOI":"10.3390\/cancers13174287","article-title":"Breast cancer\u2014epidemiology, risk factors, classification, prognostic markers, and current treatment strategies\u2014an updated review","volume":"13","author":"\u0141ukasiewicz","year":"","journal-title":"Cancers (Basel)"},{"key":"B152","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/1475-2867-13-95","article-title":"MiRNA-497 regulates cell growth and invasion by targeting cyclin E1 in breast cancer","volume":"13","author":"Luo","year":"2013","journal-title":"Cancer Cell Int."},{"key":"B153","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.omto.2020.10.008","article-title":"Mesenchymal stem cell-secreted exosome promotes chemoresistance in breast cancer via enhancing miR-21-5p-mediated S100A6 expression","volume":"19","author":"Luo","year":"2020","journal-title":"Mol. Ther-Oncolytics"},{"key":"B154","doi-asserted-by":"publisher","first-page":"BSR20193974","DOI":"10.1042\/BSR20193974","article-title":"Meta-analysis of the clinicopathological significance of miRNA-145 in breast cancer","volume":"40","author":"Lv","year":"2020","journal-title":"Biosci. Rep."},{"key":"B155","doi-asserted-by":"publisher","first-page":"2415","DOI":"10.3390\/cells10092415","article-title":"The roles of the Let-7 family of MicroRNAs in the regulation of cancer stemness","volume":"10","author":"Ma","year":"2021","journal-title":"Cells"},{"key":"B156","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1007\/s13346-020-00768-7","article-title":"miR-29b and retinoic acid co-delivery: a promising tool to induce a synergistic antitumoral effect in non-small cell lung cancer cells","volume":"10","author":"Magalh\u00e3es","year":"2020","journal-title":"Drug Deliv. Transl. Res."},{"key":"B157","doi-asserted-by":"publisher","first-page":"234","DOI":"10.3390\/genes13020234","article-title":"Role of the mediator complex and MicroRNAs in breast cancer etiology","volume":"13","author":"Maldonado","year":"2022","journal-title":"Genes (Basel)"},{"key":"B158","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.4251\/wjgo.v13.i11.1561","article-title":"Extracellular vesicles: general features and usefulness in diagnosis and therapeutic management of colorectal cancer","volume":"13","author":"Mammes","year":"2021","journal-title":"World J. Gastrointest. Oncol."},{"key":"B159","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1158\/0008-5472.CAN-18-1397","article-title":"miR-146a controls immune response in the melanoma microenvironment","volume":"79","author":"Mastroianni","year":"2019","journal-title":"Cancer Res."},{"key":"B160","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.3390\/ijms20092304","article-title":"Control mechanisms of the tumor suppressor PDCD4: expression and functions","volume":"20","author":"Matsuhashi","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"B161","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1186\/s12885-019-5636-y","article-title":"Circulating microRNAs miR-331 and miR-195 differentiate local luminal a from metastatic breast cancer","volume":"19","author":"McAnena","year":"2019","journal-title":"BMC Cancer"},{"key":"B162","doi-asserted-by":"publisher","first-page":"6456","DOI":"10.1002\/cam4.4158","article-title":"Relationship of established risk factors with breast cancer subtypes","volume":"10","author":"McCarthy","year":"2021","journal-title":"Cancer Med."},{"key":"B163","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s10555-015-9551-7","article-title":"Metastatic breast cancer: the potential of miRNA for diagnosis and treatment monitoring","volume":"34","author":"McGuire","year":"2015","journal-title":"Cancer Metastasis Rev."},{"key":"B164","doi-asserted-by":"publisher","first-page":"130","DOI":"10.4103\/jrms.JRMS_967_16","article-title":"Therapeutic impacts of microRNAs in breast cancer by their roles in regulating processes involved in this disease","volume":"22","author":"Mehrgou","year":"2017","journal-title":"J. Res. Med. Sci. Off. J. Isfahan Univ. Med. Sci."},{"key":"B165","doi-asserted-by":"publisher","first-page":"106041","DOI":"10.1016\/j.phrs.2021.106041","article-title":"Crosstalk between non-coding RNAs expression profile, drug resistance and immune response in breast cancer","volume":"176","author":"Miraghel","year":"2022","journal-title":"Pharmacol. Res."},{"key":"B166","doi-asserted-by":"publisher","first-page":"7077","DOI":"10.1016\/j.biomaterials.2014.04.053","article-title":"Efficacy of gemcitabine conjugated and miRNA-205 complexed micelles for treatment of advanced pancreatic cancer","volume":"35","author":"Mittal","year":"2014","journal-title":"Biomaterials"},{"key":"B167","doi-asserted-by":"publisher","first-page":"e5769591","DOI":"10.1155\/2018\/5769591","article-title":"The molecular basis and therapeutic potential of let-7 MicroRNAs against colorectal cancer","volume":"2018","author":"Mizuno","year":"2018","journal-title":"Can. J. Gastroenterol. Hepatol."},{"key":"B168","doi-asserted-by":"publisher","first-page":"8993","DOI":"10.1007\/s13277-015-4513-9","article-title":"MicroRNA-340 inhibits the migration, invasion, and metastasis of breast cancer cells by targeting Wnt pathway","volume":"37","author":"Mohammadi-Yeganeh","year":"2016","journal-title":"Tumor Biol."},{"key":"B169","doi-asserted-by":"publisher","first-page":"151","DOI":"10.2147\/BCTT.S176070","article-title":"Epidemiological characteristics of and risk factors for breast cancer in the world","volume":"11","author":"Momenimovahed","year":"2019","journal-title":"Breast Cancer - Targets Ther."},{"key":"B170","doi-asserted-by":"publisher","first-page":"108230","DOI":"10.1016\/j.celrep.2020.108230","article-title":"The mTORC1\/S6K\/PDCD4\/eIF4A axis determines outcome of mitotic arrest","volume":"33","author":"Moustafa-Kamal","year":"2020","journal-title":"Cell Rep."},{"key":"B171","doi-asserted-by":"publisher","first-page":"6554","DOI":"10.1158\/0008-5472.CAN-13-1841","article-title":"miRNA dysregulation in breast cancer","volume":"73","author":"Mulrane","year":"2013","journal-title":"Cancer Res."},{"key":"B172","doi-asserted-by":"publisher","first-page":"135","DOI":"10.3389\/fonc.2012.00135","article-title":"Mechanisms of telomere loss and their consequences for chromosome instability","volume":"2","author":"Muraki","year":"2012","journal-title":"Front. Oncol."},{"key":"B173","doi-asserted-by":"publisher","DOI":"10.12692\/ijb\/14.4.492-496","article-title":"Risk factors, genetic mutations and prevention of breast cancer","volume":"14","author":"Naeem","year":"2019","journal-title":"Int. J. Biosci."},{"key":"B174","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.1111\/febs.16422","article-title":"The intricate balance between microRNA\u2010induced mRNA decay and translational repression","volume":"290","author":"Naeli","year":"2023","journal-title":"FEBS J."},{"key":"B175","doi-asserted-by":"publisher","first-page":"6424","DOI":"10.1002\/jcp.29640","article-title":"The role of miR\u201034 in cancer drug resistance","volume":"235","author":"Naghizadeh","year":"2020","journal-title":"J. Cell Physiol."},{"key":"B176","doi-asserted-by":"publisher","first-page":"9650","DOI":"10.1038\/srep09650","article-title":"HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGF\u03b2-signaling in hypoxic microenvironment","volume":"5","author":"Nagpal","year":"2015","journal-title":"Sci. Rep."},{"key":"B177","doi-asserted-by":"publisher","first-page":"144453","DOI":"10.1016\/j.gene.2020.144453","article-title":"Role of miR-21 as an authentic oncogene in mediating drug resistance in breast cancer","volume":"738","author":"Najjary","year":"2020","journal-title":"Gene"},{"key":"B178","doi-asserted-by":"publisher","first-page":"679210","DOI":"10.3389\/fmicb.2021.679210","article-title":"RNA virus-encoded miRNAs: current insights and future challenges","volume":"12","author":"Nanbo","year":"2021","journal-title":"Front. Microbiol."},{"key":"B179","article-title":"How does the immune system work?","volume-title":"InformedHealth.org","year":"2020"},{"key":"B180","doi-asserted-by":"publisher","first-page":"2300","DOI":"10.3892\/ijo.2018.4547","article-title":"Induction of apoptosis and G1 phase cell cycle arrest by Aster incisus in AGS gastric adenocarcinoma cells","volume":"53","author":"Ngabire","year":"2018","journal-title":"Int. J. Oncol."},{"key":"B181","doi-asserted-by":"publisher","first-page":"2579","DOI":"10.1093\/nar\/gkaa018","article-title":"The internal loops in the lower stem of primary microRNA transcripts facilitate single cleavage of human Microprocessor","volume":"48","author":"Nguyen","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"B182","doi-asserted-by":"publisher","first-page":"10578","DOI":"10.1021\/acsami.9b00634","article-title":"Delivery of liver-specific miRNA-122 using a targeted macromolecular prodrug toward synergistic therapy for hepatocellular carcinoma","volume":"11","author":"Ning","year":"2019","journal-title":"ACS Appl. Mat. Interfaces"},{"key":"B183","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejca.2016.11.004","article-title":"The roles of oncogenic miRNAs and their therapeutic importance in breast cancer","volume":"72","author":"O\u2019Bryan","year":"2017","journal-title":"Eur. J. Cancer"},{"key":"B184","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1186\/bcr2484","article-title":"MicroRNAs and their target gene networks in breast cancer","volume":"12","author":"O\u2019Day","year":"2010","journal-title":"Breast Cancer Res."},{"key":"B185","doi-asserted-by":"publisher","first-page":"45","DOI":"10.4331\/wjbc.v8.i1.45","article-title":"Role of microRNAs in translation regulation and cancer","volume":"8","author":"Oliveto","year":"2017","journal-title":"World J. Biol. Chem."},{"key":"B186","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/j.gene.2018.11.036","article-title":"Evaluation of miRNA-9 and miRNA-34a as potential biomarkers for diagnosis of breast cancer in Iranian women","volume":"687","author":"Orangi","year":"2019","journal-title":"Gene"},{"key":"B187","doi-asserted-by":"publisher","first-page":"708765","DOI":"10.3389\/fonc.2021.708765","article-title":"Tumor suppressor miRNA in cancer cells and the tumor microenvironment: mechanism of deregulation and clinical implications","volume":"11","author":"Otmani","year":"2021","journal-title":"Front. Oncol."},{"key":"B188","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s13402-017-0335-7","article-title":"MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR\/HIF-1\u03b1\/VEGF signaling axis in breast cancer cells","volume":"40","author":"Pakravan","year":"2017","journal-title":"Cell Oncol."},{"key":"B189","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1002\/cac2.12138","article-title":"EMT\u2010associated microRNAs and their roles in cancer stemness and drug resistance","volume":"41","author":"Pan","year":"2021","journal-title":"Cancer Commun."},{"key":"B190","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1016\/j.biopha.2016.08.058","article-title":"MicroRNA-421 inhibits breast cancer metastasis by targeting metastasis associated 1","volume":"83","author":"Pan","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"B191","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.3390\/cells8121642","article-title":"The microbiome\u2013estrogen connection and breast cancer risk","volume":"8","author":"Parida","year":"2019","journal-title":"Cells"},{"key":"B192","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/s41580-021-00417-y","article-title":"Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression","volume":"23","author":"Passmore","year":"2022","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"B193","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/s10549-020-05542-4","article-title":"Breast cancer tumor histopathology, stage at presentation, and treatment in the extremes of age","volume":"180","author":"Plichta","year":"2020","journal-title":"Breast Cancer Res. Treat."},{"key":"B194","doi-asserted-by":"publisher","first-page":"3431","DOI":"10.1038\/s41467-020-17249-7","article-title":"Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolution","volume":"11","author":"Pommier","year":"2020","journal-title":"Nat. Commun."},{"key":"B195","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/s40291-020-00476-5","article-title":"Prognostic value of melanoma-associated antigen-A (MAGE-A) gene expression in various human cancers: a systematic review and meta-analysis of 7428 patients and 44 studies","volume":"24","author":"Poojary","year":"2020","journal-title":"Mol. Diagn Ther."},{"key":"B196","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s00018-018-2940-7","article-title":"Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression","volume":"76","author":"Pu","year":"2019","journal-title":"Cell Mol. Life Sci. CMLS"},{"key":"B197","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1080\/15476286.2019.1600999","article-title":"MiR-195 regulates mitochondrial function by targeting mitofusin-2 in breast cancer cells","volume":"16","author":"Purohit","year":"2019","journal-title":"RNA Biol."},{"key":"B198","doi-asserted-by":"publisher","first-page":"8905","DOI":"10.3390\/ijms21238905","article-title":"Novel miRNA targets and therapies in the triple-negative breast cancer microenvironment: an emerging hope for a challenging disease","volume":"21","author":"Qattan","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"B199","doi-asserted-by":"publisher","first-page":"2322","DOI":"10.1016\/j.biomaterials.2013.11.039","article-title":"Star-branched amphiphilic PLA-b-PDMAEMA copolymers for co-delivery of miR-21 inhibitor and doxorubicin to treat glioma","volume":"35","author":"Qian","year":"2014","journal-title":"Biomaterials"},{"key":"B200","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1002\/bit.28029","article-title":"Biogenesis and mechanisms of microRNA-mediated gene regulation","volume":"119","author":"Rani","year":"2022","journal-title":"Biotechnol. Bioeng."},{"key":"B201","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.biochi.2023.03.014","article-title":"Cancer stem cell-derived exosome-induced metastatic cancer: an orchestra within the tumor microenvironment","volume":"212","author":"Rashid","year":"2023","journal-title":"Biochimie"},{"key":"B202","doi-asserted-by":"publisher","first-page":"2210","DOI":"10.3390\/ijms22042210","article-title":"Therapeutic targeting of MicroRNAs in the tumor microenvironment","volume":"22","author":"Raue","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"B203","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s43046-022-00120-9","article-title":"Significance of metastamiR-10b in breast cancer therapeutics","volume":"34","author":"Raval","year":"2022","journal-title":"J. Egypt Natl. Cancer Inst."},{"key":"B204","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.2217\/epi-2016-0035","article-title":"Clinical development of TargomiRs, a miRNA mimic-based treatment for patients with recurrent thoracic cancer","volume":"8","author":"Reid","year":"2016","journal-title":"Epigenomics"},{"key":"B205","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1163\/156856209X415828","article-title":"Co-delivery of as-miR-21 and 5-FU by poly (amidoamine) dendrimer attenuates human glioma cell growth in vitro","volume":"21","author":"Ren","year":"2010","journal-title":"J. Biomater. Sci. Polym. Ed."},{"key":"B206","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.jconrel.2016.03.008","article-title":"Sequential co-delivery of miR-21 inhibitor followed by burst release doxorubicin using NIR-responsive hollow gold nanoparticle to enhance anticancer efficacy","volume":"228","author":"Ren","year":"2016","journal-title":"J. Control. Release"},{"key":"B207","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1007\/s00280-017-3302-0","article-title":"WBP2 modulates G1\/S transition in ER+ breast cancer cells and is a direct target of miR-206","volume":"79","author":"Ren","year":"2017","journal-title":"Cancer Chemother. Pharmacol."},{"key":"B208","doi-asserted-by":"publisher","first-page":"5133","DOI":"10.3892\/mmr.2018.9525","article-title":"Salmonella-induced miR-155 enhances necroptotic death in macrophage cells via targeting RIP1\/3","volume":"18","author":"Ro","year":"2018","journal-title":"Mol. Med. Rep."},{"key":"B209","doi-asserted-by":"publisher","first-page":"185","DOI":"10.3233\/JHD-200002","article-title":"Huntington\u2019s disease clinical trials corner: april 2020","volume":"9","author":"Rodrigues","year":"2020","journal-title":"J. Huntingt Dis."},{"key":"B210","doi-asserted-by":"publisher","first-page":"19507","DOI":"10.18632\/oncotarget.14470","article-title":"MiR-24 induces chemotherapy resistance and hypoxic advantage in breast cancer","volume":"8","author":"Roscigno","year":"2017","journal-title":"Oncotarget"},{"key":"B211","doi-asserted-by":"publisher","first-page":"4387","DOI":"10.3892\/etm.2018.6744","article-title":"MicroRNA-34a suppresses breast cancer cell proliferation and invasion by targeting Notch1","volume":"16","author":"Rui","year":"2018","journal-title":"Exp. Ther. Med."},{"key":"B212","doi-asserted-by":"publisher","first-page":"118256","DOI":"10.1016\/j.lfs.2020.118256","article-title":"Role of microRNA in forming breast carcinoma","volume":"259","author":"Saikia","year":"2020","journal-title":"Life Sci."},{"key":"B213","doi-asserted-by":"publisher","first-page":"646","DOI":"10.3390\/cancers11050646","article-title":"Gene expression and miRNAs profiling: function and regulation in human epidermal growth factor receptor 2 (HER2)-Positive breast cancer","volume":"11","author":"Sareyeldin","year":"2019","journal-title":"Cancers"},{"key":"B214","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1101\/gad.335679.119","article-title":"Structure and mechanism of the RNA polymerase II transcription machinery","volume":"34","author":"Schier","year":"2020","journal-title":"Genes Dev."},{"key":"B215","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3390\/ncrna7010003","article-title":"The role of lncRNAs in gene expression regulation through mRNA stabilization","volume":"7","author":"Sebastian-delaCruz","year":"2021","journal-title":"Non-Coding RNA"},{"key":"B216","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1080\/17460441.2020.1765770","article-title":"Challenges identifying efficacious miRNA therapeutics for cancer","volume":"15","author":"Segal","year":"2020","journal-title":"Expert Opin. Drug Discov."},{"key":"B217","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1186\/s12885-022-09698-8","article-title":"Meta-analysis of diagnostic cell-free circulating microRNAs for breast cancer detection","volume":"22","author":"Sehovic","year":"2022","journal-title":"BMC Cancer"},{"key":"B218","doi-asserted-by":"publisher","first-page":"P268","DOI":"10.1186\/2051-1426-2-s3-p268","article-title":"Role of miRs in immune suppression","volume":"2","author":"Seliger","year":"2014","journal-title":"J. Immunother. Cancer"},{"key":"B219","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1093\/carcin\/bgz011","article-title":"MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-\u03baB signaling","volume":"40","author":"Senthil Kumar","year":"2019","journal-title":"Carcinogenesis"},{"key":"B220","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1261\/rna.060657.117","article-title":"P53-miR-191-SOX4 regulatory loop affects apoptosis in breast cancer","volume":"23","author":"Sharma","year":"2017","journal-title":"Rna"},{"key":"B221","doi-asserted-by":"publisher","first-page":"e163010","DOI":"10.1172\/JCI163010","article-title":"Harnessing tumorous flaws for immune supremacy: is miRNA-155 the weak link in breast cancer progression?","volume":"132","author":"Sharma","year":"","journal-title":"J. Clin. Invest."},{"key":"B222","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12026-021-09247-8","article-title":"Host miRNA and immune cell interactions: relevance in nano-therapeutics for human health","volume":"70","author":"Sharma","year":"","journal-title":"Immunol. Res."},{"key":"B223","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1007\/s13277-014-2794-z","article-title":"MiR-492 contributes to cell proliferation and cell cycle of human breast cancer cells by suppressing SOX7 expression","volume":"36","author":"Shen","year":"2015","journal-title":"Tumor Biol."},{"key":"B224","doi-asserted-by":"publisher","first-page":"6478653","DOI":"10.1155\/2020\/6478653","article-title":"miR-21 overexpression promotes esophageal squamous cell carcinoma invasion and migration by repressing tropomyosin 1","volume":"2020","author":"Shen","year":"2020","journal-title":"Gastroenterol. Res. Pract."},{"key":"B225","doi-asserted-by":"publisher","first-page":"3667","DOI":"10.3892\/mmr.2019.10044","article-title":"MicroRNA-124 suppresses cell proliferation and invasion of triple negative breast cancer cells by targeting STAT3","volume":"19","author":"Shi","year":"2019","journal-title":"Mol. Med. Rep."},{"key":"B226","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.jconrel.2014.09.005","article-title":"Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression","volume":"194","author":"Shi","year":"2014","journal-title":"J. Control. Release"},{"key":"B227","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2019.05.017","article-title":"MicroRNAs in cancer cell death pathways: apoptosis and necroptosis","volume":"139","author":"Shirjang","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"B228","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1016\/j.molonc.2015.01.008","article-title":"MicroRNA-30c-2-3p negatively regulates NF-\u03baB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer","volume":"9","author":"Shukla","year":"2015","journal-title":"Mol. Oncol."},{"key":"B229","doi-asserted-by":"publisher","first-page":"2799","DOI":"10.1038\/sj.onc.1210083","article-title":"miR-21-mediated tumor growth","volume":"26","author":"Si","year":"2007","journal-title":"Oncogene"},{"key":"B230","doi-asserted-by":"publisher","first-page":"144888","DOI":"10.1016\/j.gene.2020.144888","article-title":"Immunomodulatory role for MicroRNAs: regulation of PD-1\/PD-L1 and CTLA-4 immune checkpoints expression","volume":"754","author":"Skafi","year":"2020","journal-title":"Gene"},{"key":"B231","doi-asserted-by":"publisher","first-page":"2805","DOI":"10.3390\/ijms23052805","article-title":"miRNAs in cancer (review of literature)","volume":"23","author":"Smolarz","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B232","doi-asserted-by":"publisher","first-page":"111101","DOI":"10.1016\/j.cellsig.2024.111101","article-title":"Exosomal miR-122-3p represses the growth and metastasis of MCF-7\/ADR cells by targeting GRK4-mediated activation of the Wnt\/\u03b2-catenin pathway","volume":"117","author":"Song","year":"2024","journal-title":"Cell Signal"},{"key":"B233","doi-asserted-by":"publisher","first-page":"2768","DOI":"10.1039\/d0tb00346h","article-title":"Efficient co-delivery of microRNA 21 inhibitor and doxorubicin to cancer cells using core\u2013shell tecto dendrimers formed via supramolecular host\u2013guest assembly","volume":"8","author":"Song","year":"2020","journal-title":"J. Mater Chem. B"},{"key":"B234","doi-asserted-by":"publisher","first-page":"1533033818809997","DOI":"10.1177\/1533033818809997","article-title":"RETRACTED: MicroRNA-22 suppresses breast cancer cell growth and increases paclitaxel sensitivity by targeting NRAS","volume":"17","author":"Song","year":"2018","journal-title":"Technol. Cancer Res. Treat."},{"key":"B235","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1158\/2159-8290.CD-17-0858","article-title":"More T cells versus better T cells in patients with breast cancer","volume":"7","author":"Speiser","year":"2017","journal-title":"Cancer Discov."},{"key":"B236","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1758-907X-3-1","article-title":"Inhibition of microRNA function by antimiR oligonucleotides","volume":"3","author":"Stenvang","year":"2012","journal-title":"Silence"},{"key":"B237","doi-asserted-by":"publisher","first-page":"119","DOI":"10.3892\/or.2022.8330","article-title":"[Retracted] MicroRNA\u2011133a acts as a tumour suppressor in breast cancer through targeting LASP1","volume":"48","author":"Sui","year":"2022","journal-title":"Oncol. Rep."},{"key":"B238","doi-asserted-by":"publisher","first-page":"8271","DOI":"10.1038\/s41598-020-65207-6","article-title":"Exosomal miR-21 promotes proliferation, invasion and therapy resistance of colon adenocarcinoma cells through its target PDCD4","volume":"10","author":"Sun","year":"2020","journal-title":"Sci. Rep."},{"key":"B239","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1007\/s13346-020-00779-4","article-title":"Simultaneous delivery of anti-miRNA and docetaxel with supramolecular self-assembled \u201cchitosome\u201d for improving chemosensitivity of triple negative breast cancer cells","volume":"11","author":"Sun","year":"2021","journal-title":"Drug Deliv. Transl. Res."},{"key":"B240","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.7150\/ijbs.21635","article-title":"Risk factors and preventions of breast cancer","volume":"13","author":"Sun","year":"2017","journal-title":"Int. J. Biol. Sci."},{"key":"B241","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"key":"B242","doi-asserted-by":"publisher","first-page":"3268","DOI":"10.3390\/cimb45040213","article-title":"The potential association between E2F2, MDM2 and p16 protein concentration and selected sociodemographic and clinicopathological characteristics of patients with oral squamous cell carcinoma","volume":"45","author":"\u015awi\u0119tek","year":"2023","journal-title":"Curr. Issues Mol. Biol."},{"key":"B243","doi-asserted-by":"publisher","first-page":"560","DOI":"10.2174\/1568009622666220401093316","article-title":"Pharmacological inhibition of exosome machinery: an emerging prospect in cancer therapeutics","volume":"22","author":"Syeda","year":"2022","journal-title":"Curr. Cancer Drug Targets"},{"key":"B244","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.jconrel.2019.02.014","article-title":"Co-delivery of miR-181a and melphalan by lipid nanoparticles for treatment of seeded retinoblastoma","volume":"298","author":"Tabatabaei","year":"2019","journal-title":"J. Control. Release"},{"key":"B245","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s13578-020-0381-0","article-title":"Apoptotic functions of microRNAs in pathogenesis, diagnosis, and treatment of endometriosis","volume":"10","author":"Taghavipour","year":"2020","journal-title":"Cell Biosci."},{"key":"B246","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s11010-018-3322-z","article-title":"Cytoplasmic localization of programmed cell death 4 contributes to its anti-apoptotic function","volume":"448","author":"Takaki","year":"2018","journal-title":"Mol. Cell Biochem."},{"key":"B247","doi-asserted-by":"publisher","first-page":"876451","DOI":"10.3389\/fonc.2022.876451","article-title":"Tumour microenvironment-immune cell interactions influencing breast cancer heterogeneity and disease progression","volume":"12","author":"Tan","year":"2022","journal-title":"Front. Oncol."},{"key":"B248","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1038\/s41523-021-00293-x","article-title":"Long non-coding RNA MIR200CHG promotes breast cancer proliferation, invasion, and drug resistance by interacting with and stabilizing YB-1","volume":"7","author":"Tang","year":"2021","journal-title":"NPJ Breast Cancer"},{"key":"B249","doi-asserted-by":"publisher","first-page":"929677","DOI":"10.3389\/fimmu.2022.929677","article-title":"miR-aculous new avenues for cancer immunotherapy","volume":"13","author":"Tang","year":"2022","journal-title":"Front. Immunol."},{"key":"B250","doi-asserted-by":"publisher","first-page":"a036996","DOI":"10.1101\/cshperspect.a036996","article-title":"The role of PTEN in innate and adaptive immunity","volume":"9","author":"Taylor","year":"2019","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"B251","doi-asserted-by":"publisher","first-page":"268","DOI":"10.15252\/emmm.201505495","article-title":"Therapeutic potential of targeting micro RNA\u201010b in established intracranial glioblastoma: first steps toward the clinic","volume":"8","author":"Teplyuk","year":"2016","journal-title":"EMBO Mol. Med."},{"key":"B252","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3390\/ncrna3030022","article-title":"miR-146 and miR-155: two key modulators of immune response and tumor development","volume":"3","author":"Testa","year":"2017","journal-title":"Non-Coding RNA"},{"key":"B253","doi-asserted-by":"publisher","first-page":"668534","DOI":"10.3389\/fmolb.2021.668534","article-title":"MicroRNAs regulating tumor immune response in the prediction of the outcome in patients with breast cancer","volume":"8","author":"Thomopoulou","year":"2021","journal-title":"Front. Mol. Biosci."},{"key":"B254","doi-asserted-by":"publisher","first-page":"731479","DOI":"10.1155\/2015\/731479","article-title":"Challenges in using circulating miRNAs as cancer biomarkers","volume":"2015","author":"Tiberio","year":"2015","journal-title":"Biomed. Res. Int."},{"key":"B255","doi-asserted-by":"publisher","first-page":"41309","DOI":"10.1038\/srep41309","article-title":"The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene","volume":"7","author":"Tormo","year":"2017","journal-title":"Sci. Rep."},{"key":"B256","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1038\/s41580-018-0059-1","article-title":"Regulation of microRNA biogenesis and its crosstalk with other cellular pathways","volume":"20","author":"Treiber","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"B257","doi-asserted-by":"publisher","first-page":"487","DOI":"10.3390\/biom10030487","article-title":"TGF-\u0392 signaling","volume":"10","author":"Tzavlaki","year":"2020","journal-title":"Biomolecules"},{"key":"B258","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jconrel.2018.12.031","article-title":"Dual delivery nanoscale device for miR-345 and gemcitabine co-delivery to treat pancreatic cancer","volume":"294","author":"Uz","year":"2019","journal-title":"J. Control. Release"},{"key":"B259","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.omtn.2020.06.003","article-title":"Dual regulation of miR-34a and Notch signaling in triple-negative breast cancer by antibody\/miRNA nanocarriers","volume":"21","author":"Valcourt","year":"2020","journal-title":"Mol. Ther-Nucleic Acids"},{"key":"B260","doi-asserted-by":"publisher","first-page":"12974","DOI":"10.1038\/s41598-022-16898-6","article-title":"HER2-low breast cancer shows a lower immune response compared to HER2-negative cases","volume":"12","author":"van den Ende","year":"2022","journal-title":"Sci. Rep."},{"key":"B261","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s13058-015-0526-y","article-title":"Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management","volume":"17","author":"van Schooneveld","year":"2015","journal-title":"Breast Cancer Res."},{"key":"B262","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1016\/S1470-2045(17)30621-6","article-title":"Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study","volume":"18","author":"Van Zandwijk","year":"2017","journal-title":"Lancet Oncol."},{"key":"B263","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1038\/s41598-018-37813-y","article-title":"Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing","volume":"9","author":"Vautrin","year":"2019","journal-title":"Sci. Rep."},{"key":"B264","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.ejphar.2017.03.016","article-title":"miR-455 inhibits breast cancer cell proliferation through targeting CDK14","volume":"807","author":"Wang","year":"","journal-title":"Eur. J. Pharmacol."},{"key":"B265","doi-asserted-by":"publisher","first-page":"22767","DOI":"10.1021\/acsami.8b07698","article-title":"Stimuli-responsive nanocarrier for co-delivery of MiR-31 and doxorubicin to suppress high MtEF4 cancer","volume":"10","author":"Wang","year":"","journal-title":"ACS Appl. Mater Interfaces"},{"key":"B266","doi-asserted-by":"publisher","first-page":"5033","DOI":"10.3892\/ol.2019.10862","article-title":"Multiple roles of microRNA-146a in immune responses and hepatocellular carcinoma","volume":"18","author":"Wang","year":"2019","journal-title":"Oncol. Lett."},{"key":"B267","doi-asserted-by":"publisher","first-page":"e157248","DOI":"10.1172\/JCI157248","article-title":"Breast cancer cell\u2013derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function","volume":"132","author":"Wang","year":"","journal-title":"J. Clin. Invest."},{"key":"B268","doi-asserted-by":"publisher","first-page":"e157248","DOI":"10.1172\/JCI157248","article-title":"Breast cancer cell\u2013derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function","volume":"132","author":"Wang","year":"","journal-title":"J. Clin. Invest."},{"key":"B269","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1159\/000481445","article-title":"MicroRNA-101 inhibits growth, proliferation and migration and induces apoptosis of breast cancer cells by targeting sex-determining region Y-Box 2","volume":"43","author":"Wang","year":"","journal-title":"Cell Physiol. Biochem."},{"key":"B270","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/s13568-020-00990-z","article-title":"CD59 receptor targeted delivery of miRNA-1284 and cisplatin-loaded liposomes for effective therapeutic efficacy against cervical cancer cells","volume":"10","author":"Wang","year":"2020","journal-title":"Amb. Express"},{"key":"B271","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1007\/s12094-017-1805-0","article-title":"Effect of exosome biomarkers for diagnosis and prognosis of breast cancer patients","volume":"20","author":"Wang","year":"","journal-title":"Clin. Transl. Oncol."},{"key":"B272","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1111\/boc.201800014","article-title":"The role of Pdcd4 in tumour suppression and protein translation","volume":"28","author":"Wang","year":"2018","journal-title":"Biol. Cell."},{"key":"B273","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.nano.2015.09.014","article-title":"Hyaluronic acid-coated PEI-PLGA nanoparticles mediated co-delivery of doxorubicin and miR-542-3p for triple negative breast cancer therapy","volume":"12","author":"Wang","year":"2016","journal-title":"Nanomedicine"},{"key":"B274","first-page":"5017","article-title":"MicroRNA-204 targets JAK2 in breast cancer and induces cell apoptosis through the STAT3\/BCl-2\/survivin pathway","volume":"8","author":"Wang","year":"2015","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"B275","doi-asserted-by":"publisher","first-page":"109473","DOI":"10.1016\/j.biopha.2019.109473","article-title":"Dual delivery nanoscale device for miR-451 and adriamycin co-delivery to combat multidrug resistant in bladder cancer","volume":"122","author":"Wei","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"B276","doi-asserted-by":"publisher","first-page":"29","DOI":"10.3390\/ncrna6030029","article-title":"Potential miRNAs for miRNA-based therapeutics in breast cancer","volume":"6","author":"Wong","year":"2020","journal-title":"Non-Coding RNA"},{"key":"B277","doi-asserted-by":"publisher","first-page":"630","DOI":"10.3109\/01443615.2014.920782","article-title":"Meta-analysis of the differentially expressed breast cancer-related microRNA expression profiles","volume":"34","author":"Wu","year":"2014","journal-title":"J. Obstet. Gynaecol."},{"key":"B278","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.3892\/or.2015.4529","article-title":"miR-497 suppresses angiogenesis in breast carcinoma by targeting HIF-1\u03b1","volume":"35","author":"Wu","year":"2016","journal-title":"Oncol. Rep."},{"key":"B279","doi-asserted-by":"publisher","first-page":"3416","DOI":"10.3892\/or.2018.6741","article-title":"MicroRNA-424 serves an anti-oncogenic role by targeting cyclin-dependent kinase 1 in breast cancer cells","volume":"40","author":"Xie","year":"2018","journal-title":"Oncol. Rep."},{"key":"B280","doi-asserted-by":"publisher","first-page":"e0185565","DOI":"10.1371\/journal.pone.0185565","article-title":"MicroRNA-193a inhibits breast cancer proliferation and metastasis by downregulating WT1","volume":"12","author":"Xie","year":"2017","journal-title":"PloS One"},{"key":"B281","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.biomaterials.2019.04.025","article-title":"Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis","volume":"210","author":"Xu","year":"2019","journal-title":"Biomaterials"},{"key":"B282","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1111\/cas.13212","article-title":"PVT 1\u2010derived miR\u20101207\u20105p promotes breast cancer cell growth by targeting STAT 6","volume":"108","author":"Yan","year":"2017","journal-title":"Cancer Sci."},{"key":"B283","doi-asserted-by":"publisher","first-page":"468","DOI":"10.4048\/jbc.2018.21.e59","article-title":"The open issues regarding cyclin-dependent kinase 4\/6 inhibitors in the management of advanced breast cancer","volume":"21","author":"Yang","year":"","journal-title":"J. Breast Cancer"},{"key":"B284","doi-asserted-by":"publisher","first-page":"371","DOI":"10.4048\/jbc.2018.21.e60","article-title":"miR-195\/miR-497 regulate CD274 expression of immune regulatory ligands in triple-negative breast cancer","volume":"21","author":"Yang","year":"","journal-title":"J. Breast Cancer"},{"key":"B285","doi-asserted-by":"publisher","first-page":"142","DOI":"10.7150\/thno.13130","article-title":"Anti-tumor efficiency of lipid-coated cisplatin nanoparticles Co-loaded with MicroRNA-375","volume":"6","author":"Yang","year":"2016","journal-title":"Theranostics"},{"key":"B286","doi-asserted-by":"publisher","first-page":"2819","DOI":"10.1016\/j.apsb.2021.06.003","article-title":"Combination therapy with miR34a and doxorubicin synergistically inhibits Dox-resistant breast cancer progression via down-regulation of Snail through suppressing Notch\/NF-\u03baB and RAS\/RAF\/MEK\/ERK signaling pathway","volume":"11","author":"Yang","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"B287","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.jconrel.2016.04.034","article-title":"Reducible self-assembling cationic polypeptide-based micelles mediate co-delivery of doxorubicin and microRNA-34a for androgen-independent prostate cancer therapy","volume":"232","author":"Yao","year":"2016","journal-title":"J. Control. Release"},{"key":"B288","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1016\/j.ymthe.2019.04.018","article-title":"Delivery of anti-miRNA for triple-negative breast cancer therapy using RNA nanoparticles targeting stem cell marker CD133","volume":"27","author":"Yin","year":"2019","journal-title":"Mol. Ther."},{"key":"B289","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1002\/hed.26089","article-title":"MicroRNA-based risk scoring system to identify early-stage oral squamous cell carcinoma patients at high-risk for cancer-specific mortality","volume":"42","author":"Yoon","year":"2020","journal-title":"Head. Neck"},{"key":"B290","doi-asserted-by":"publisher","first-page":"82","DOI":"10.2174\/2211536608666190919161849","article-title":"MicroRNAs determining carcinogenesis by regulating oncogenes and tumor suppressor genes during cell cycle","volume":"9","author":"Zacharias","year":"2020","journal-title":"MicroRNA"},{"key":"B291","doi-asserted-by":"publisher","first-page":"e2529","DOI":"10.1038\/cddis.2016.440","article-title":"MicroRNA-494 inhibits breast cancer progression by directly targeting PAK1","volume":"8","author":"Zhan","year":"2018","journal-title":"Cell Death Dis."},{"key":"B292","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s13058-017-0858-x","article-title":"MicroRNA-200c and microRNA-141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer","volume":"19","author":"Zhang","year":"","journal-title":"Breast Cancer Res."},{"key":"B293","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1177\/17246008211005473","article-title":"Identification of cluster of differentiation molecule-associated microRNAs as potential therapeutic targets for gastrointestinal cancer immunotherapy","volume":"36","author":"Zhang","year":"","journal-title":"Int. J. Biol. Markers."},{"key":"B294","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.biopha.2015.12.018","article-title":"MicroRNA-138 modulates metastasis and EMT in breast cancer cells by targeting vimentin","volume":"77","author":"Zhang","year":"","journal-title":"Biomed. Pharmacother. Biomedecine Pharmacother."},{"key":"B295","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1186\/s12967-014-0279-x","article-title":"Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells","volume":"12","author":"Zhang","year":"","journal-title":"J. Transl. Med."},{"key":"B296","first-page":"4710","article-title":"Overexpression of microRNA-365 inhibits breast cancer cell growth and chemo-resistance through GALNT4","volume":"20","author":"Zhang","year":"2016","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"B297","doi-asserted-by":"publisher","first-page":"153458","DOI":"10.1016\/j.prp.2021.153458","article-title":"A two-miRNA signature of upregulated miR-185-5p and miR-362-5p as a blood biomarker for breast cancer","volume":"222","author":"Zhang","year":"","journal-title":"Pathol-Res Pract."},{"key":"B298","doi-asserted-by":"publisher","first-page":"950","DOI":"10.3892\/ijo.2014.2487","article-title":"MicroRNAs in the diagnosis and prognosis of breast cancer and their therapeutic potential (review)","volume":"45","author":"Zhang","year":"","journal-title":"Int. J. Oncol."},{"key":"B299","doi-asserted-by":"publisher","first-page":"46186","DOI":"10.1038\/srep46186","article-title":"Cytosolic co-delivery of miRNA-34a and docetaxel with core-shell nanocarriers via caveolae-mediated pathway for the treatment of metastatic breast cancer","volume":"7","author":"Zhang","year":"","journal-title":"Sci. Rep."},{"key":"B300","doi-asserted-by":"publisher","first-page":"190061","DOI":"10.1098\/rsob.190061","article-title":"miR-149-3p reverses CD8+ T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells","volume":"9","author":"Zhang","year":"2019","journal-title":"Open Biol."},{"key":"B301","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1007\/s00262-020-02507-w","article-title":"miRNA-5119 regulates immune checkpoints in dendritic cells to enhance breast cancer immunotherapy","volume":"69","author":"Zhang","year":"","journal-title":"Cancer Immunol. Immunother."},{"key":"B302","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.jconrel.2014.11.010","article-title":"Simultaneous delivery of therapeutic antagomirs with paclitaxel for the management of metastatic tumors by a pH-responsive anti-microbial peptide-mediated liposomal delivery system","volume":"197","author":"Zhang","year":"","journal-title":"J. Control. Release"},{"key":"B303","doi-asserted-by":"publisher","first-page":"110160","DOI":"10.1016\/j.ecoenv.2019.110160","article-title":"ROS-mediated miR-21-5p regulates the proliferation and apoptosis of Cr(VI)-exposed L02 hepatocytes via targeting PDCD4","volume":"191","author":"Zhang","year":"","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"B304","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1089\/cbr.2017.2270","article-title":"HIF-1\u03b1 promotes breast cancer cell MCF-7 proliferation and invasion through regulating miR-210","volume":"32","author":"Zhang","year":"","journal-title":"Cancer Biother Radiopharm."},{"key":"B305","doi-asserted-by":"publisher","first-page":"1010428317692264","DOI":"10.1177\/1010428317692264","article-title":"miR-29a suppresses MCF-7 cell growth by downregulating tumor necrosis factor receptor 1","volume":"39","author":"Zhao","year":"2017","journal-title":"Tumor Biol."},{"key":"B306","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.7150\/thno.30701","article-title":"Transcriptional downregulation of miR-4306 serves as a new therapeutic target for triple negative breast cancer","volume":"9","author":"Zhao","year":"2019","journal-title":"Theranostics"},{"key":"B307","doi-asserted-by":"publisher","first-page":"e60034","DOI":"10.1371\/journal.pone.0060034","article-title":"Functionalized graphene oxide mediated adriamycin delivery and miR-21 gene silencing to overcome tumor multidrug resistance in vitro","volume":"8","author":"Zhi","year":"2013","journal-title":"PloS One"},{"key":"B308","doi-asserted-by":"publisher","first-page":"4024","DOI":"10.1002\/jcp.30145","article-title":"Methionine selenium antagonizes LPS-induced necroptosis in the chicken liver via the miR-155\/TRAF3\/MAPK axis","volume":"236","author":"Zhirong","year":"2021","journal-title":"J. Cell Physiol."},{"key":"B309","doi-asserted-by":"publisher","first-page":"824","DOI":"10.3390\/cancers15030824","article-title":"MicroRNAs with multiple targets of immune checkpoints, as a potential sensitizer for immune checkpoint inhibitors in breast cancer treatment","volume":"15","author":"Zhou","year":"","journal-title":"Cancers"},{"key":"B310","doi-asserted-by":"publisher","first-page":"824","DOI":"10.3390\/cancers15030824","article-title":"MicroRNAs with multiple targets of immune checkpoints, as a potential sensitizer for immune checkpoint inhibitors in breast cancer treatment","volume":"15","author":"Zhou","year":"","journal-title":"Cancers"},{"key":"B311","doi-asserted-by":"publisher","first-page":"e5891","DOI":"10.1590\/1414-431X20175891","article-title":"MicroRNA-143 inhibits cell growth by targeting ERK5 and MAP3K7 in breast cancer","volume":"50","author":"Zhou","year":"","journal-title":"Braz J. Med. Biol. Res."},{"key":"B312","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.nano.2016.07.016","article-title":"Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221\/222 inhibitors","volume":"13","author":"Zhou","year":"","journal-title":"Nanomedicine"}],"container-title":["Frontiers in Cell and Developmental Biology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2024.1390704\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:24:07Z","timestamp":1714004647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2024.1390704\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,25]]},"references-count":312,"alternative-id":["10.3389\/fcell.2024.1390704"],"URL":"https:\/\/doi.org\/10.3389\/fcell.2024.1390704","relation":{},"ISSN":["2296-634X"],"issn-type":[{"value":"2296-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,25]]},"article-number":"1390704"}}