{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:48:04Z","timestamp":1753890484182,"version":"3.41.2"},"reference-count":122,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell Dev. Biol."],"abstract":"<jats:p>Nephrolithiasis is one of the most common diseases in urology, characterized by notable incidence and recurrence rates, leading to significant morbidity and financial burden. Despite its prevalence, the precise mechanisms underlying stone formation remain incompletely understood, thus hindering significant advancements in kidney stone management over the past three decades. Investigating the pivotal biological molecules that govern stone formation has consistently been a challenging and high-priority task. A significant portion of mammalian genomes are transcribed into noncoding RNAs (ncRNAs), which have the ability to modulate gene expression and disease progression. They are thus emerging as a novel target class for diagnostics and pharmaceutical exploration. In recent years, the role of ncRNAs in stone formation has attracted burgeoning attention. They have been found to influence stone formation by regulating ion transportation, oxidative stress injury, inflammation, osteoblastic transformation, autophagy, and pyroptosis. These findings contributes new perspectives on the pathogenesis of nephrolithiasis. To enhance our understanding of the diagnostic and therapeutic potential of nephrolithiasis-associated ncRNAs, we summarized the expression profiles, biological functions, and clinical significance of these ncRNAs in the current review.<\/jats:p>","DOI":"10.3389\/fcell.2024.1457319","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T06:29:45Z","timestamp":1732084185000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Noncoding RNA, friend or foe for nephrolithiasis?"],"prefix":"10.3389","volume":"12","author":[{"given":"Qing","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenlu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kehua","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,11,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1080\/10715762.2020.1751835","article-title":"Oxidative stress and endoplasmic stress in calcium oxalate stone disease: the chicken or the egg?","volume":"54","author":"Albert","year":"2020","journal-title":"Free Radic. Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.eururo.2014.06.036","article-title":"Use of the National Health and Nutrition Examination Survey to calculate the impact of obesity and diabetes on cost and prevalence of urolithiasis in 2030","volume":"66","author":"Antonelli","year":"2014","journal-title":"Eur. Urol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.molcel.2014.08.019","article-title":"circRNA biogenesis competes with pre-mRNA splicing","volume":"56","author":"Ashwal-Fluss","year":"2014","journal-title":"Mol. Cell"},{"key":"B4","doi-asserted-by":"publisher","first-page":"283","DOI":"10.2174\/1389200223666220321102824","article-title":"miRNAs in SARS-CoV-2 infection: an update","volume":"23","author":"Azhar","year":"2022","journal-title":"Curr. Drug Metab."},{"key":"B5","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1186\/s12864-018-5052-8","article-title":"Changing expression profiles of long non-coding RNAs, mRNAs and circular RNAs in ethylene glycol-induced kidney calculi rats","volume":"19","author":"Cao","year":"2018","journal-title":"BMC Genomics"},{"key":"B6","doi-asserted-by":"publisher","first-page":"566506","DOI":"10.3389\/fphys.2020.566506","article-title":"Mitochondrial dysfunction and kidney stone disease","volume":"11","author":"Chaiyarit","year":"2020","journal-title":"Front. Physiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.jare.2020.08.012","article-title":"Therapeutic advances of miRNAs: a preclinical and clinical update","volume":"28","author":"Chakraborty","year":"2020","journal-title":"J. Adv. Res."},{"key":"B8","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1038\/s41392-022-00975-3","article-title":"Targeting non-coding RNAs to overcome cancer therapy resistance","volume":"7","author":"Chen","year":"","journal-title":"Signal Transduct. Target Ther."},{"key":"B9","doi-asserted-by":"publisher","first-page":"2354","DOI":"10.1016\/j.ymthe.2022.02.020","article-title":"Long noncoding RNA LINC01234 promotes hepatocellular carcinoma progression through orchestrating aspartate metabolic reprogramming","volume":"30","author":"Chen","year":"","journal-title":"Mol. Ther."},{"key":"B10","doi-asserted-by":"publisher","first-page":"104450","DOI":"10.1016\/j.yexmp.2020.104450","article-title":"miR-155 facilitates calcium oxalate crystal-induced HK-2 cell injury via targeting PI3K associated autophagy","volume":"115","author":"Chen","year":"2020","journal-title":"Exp. Mol. Pathol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"828243","DOI":"10.3389\/fimmu.2022.828243","article-title":"Characteristics of prognostic programmed cell death-related long noncoding RNAs associated with immune infiltration and therapeutic responses to colon cancer","volume":"13","author":"Chen","year":"","journal-title":"Front. Immunol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"F137","DOI":"10.1152\/ajprenal.00047.2019","article-title":"Pioglitazone decreased renal calcium oxalate crystal formation by suppressing M1 macrophage polarization via the PPAR-\u03b3-miR-23 axis","volume":"317","author":"Chen","year":"2019","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.21037\/tau-20-607","article-title":"Suppression of osteogenic-like differentiation in human renal interstitial fibroblasts by miRNA-410-3p through MSX2","volume":"9","author":"Cui","year":"2020","journal-title":"Transl. Androl. Urol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"2602717","DOI":"10.1155\/2022\/2602717","article-title":"miR-103a-3p silencing ameliorates calcium oxalate deposition in rat kidney by activating the UMOD\/TRPV5 axis","volume":"2022","author":"Cui","year":"2022","journal-title":"Dis. Markers"},{"key":"B15","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s00240-014-0703-y","article-title":"Randall's plaque as the origin of calcium oxalate kidney stones","volume":"43","author":"Daudon","year":"2015","journal-title":"Urolithiasis"},{"key":"B16","doi-asserted-by":"publisher","first-page":"733","DOI":"10.3760\/cma.j.issn.0529-5815.2018.10.004","article-title":"The role of cell-crystal reaction mediated inflammation in the formation of intrarenal calcium oxalate crystals","volume":"56","author":"Deng","year":"2018","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"B17","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1097\/MOU.0000000000000729","article-title":"Immunotherapy for stone disease","volume":"30","author":"Dominguez-Gutierrez","year":"2020","journal-title":"Curr. Opin. Urol."},{"key":"B18","first-page":"774","article-title":"Crystals, Randall's plaques and renal stones: do bone and atherosclerosis teach us something?","volume":"17","author":"Gambaro","year":"2004","journal-title":"J. Nephrol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1159\/000521795","article-title":"Mechanism of miRNA-141-3p in calcium oxalate-induced renal tubular epithelial cell injury via NLRP3-mediated pyroptosis","volume":"47","author":"Gan","year":"2022","journal-title":"Kidney Blood Press Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1172\/JCI75852","article-title":"Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways","volume":"125","author":"Gomez","year":"2015","journal-title":"J. Clin. Invest."},{"key":"B21","doi-asserted-by":"publisher","first-page":"14749","DOI":"10.18632\/aging.205286","article-title":"Downregulating miR-184 relieves calcium oxalate crystal-mediated renal cell damage via activating the Rap1 signaling pathway","volume":"15","author":"Han","year":"2023","journal-title":"Aging (Albany NY)"},{"key":"B22","doi-asserted-by":"publisher","first-page":"106418","DOI":"10.1016\/j.phrs.2022.106418","article-title":"Long non-coding RNA (lncRNA) H19 in human cancer: from proliferation and metastasis to therapy","volume":"184","author":"Hashemi","year":"2022","journal-title":"Pharmacol. Res."},{"key":"B23","doi-asserted-by":"publisher","first-page":"7167","DOI":"10.3390\/ijms23137167","article-title":"MicroRNA-based diagnosis and therapy","volume":"23","author":"Ho","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B24","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-319-42059-2_1","article-title":"Non-coding RNAs: classification, biology and functioning","volume":"937","author":"Hombach","year":"2016","journal-title":"Adv. Exp. Med. Biol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/280339a0","article-title":"Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells","volume":"280","author":"Hsu","year":"1979","journal-title":"Nature"},{"key":"B26","doi-asserted-by":"publisher","first-page":"295651","DOI":"10.1155\/2014\/295651","article-title":"Elevated levels of miR-155 in blood and urine from patients with nephrolithiasis","volume":"2014","author":"Hu","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"B27","doi-asserted-by":"publisher","first-page":"643615","DOI":"10.3389\/fimmu.2021.643615","article-title":"A diagnostic panel for acquired immune-mediated polyneuropathies based on the expression of lncRNAs","volume":"12","author":"Hussen","year":"2022","journal-title":"Front. Immunol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/nbt.2890","article-title":"Detecting and characterizing circular RNAs","volume":"32","author":"Jeck","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"e507","DOI":"10.1016\/j.urology.2013.11.004","article-title":"Does crystal deposition in genetic hypercalciuric rat kidney tissue share similarities with bone formation?","volume":"83","author":"Jia","year":"2014","journal-title":"Urology"},{"key":"B30","doi-asserted-by":"publisher","first-page":"5863617","DOI":"10.1155\/2020\/5863617","article-title":"miR-155-5p promotes oxalate- and calcium-induced kidney oxidative stress injury by suppressing MGP expression","volume":"2020","author":"Jiang","year":"2020","journal-title":"Oxid. Med. Cell Longev."},{"key":"B31","doi-asserted-by":"publisher","first-page":"2000","DOI":"10.1016\/j.bbadis.2015.06.020","article-title":"Osteogenic changes in kidneys of hyperoxaluric rats","volume":"1852","author":"Joshi","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"B32","doi-asserted-by":"publisher","first-page":"579","DOI":"10.5603\/GP.a2021.0121","article-title":"Influence of MiRNAs in gestational diabetes mellitus development","volume":"92","author":"Juchnicka","year":"2021","journal-title":"Ginekol. Pol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"256","DOI":"10.3978\/j.issn.2223-4683.2014.06.04","article-title":"Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis","volume":"3","author":"Khan","year":"2014","journal-title":"Transl. Androl. Urol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/s41581-020-00392-1","article-title":"Randall's plaque and calcium oxalate stone formation: role for immunity and inflammation","volume":"17","author":"Khan","year":"2021","journal-title":"Nat. Rev. Nephrol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"16008","DOI":"10.1038\/nrdp.2016.8","article-title":"Kidney stones","volume":"2","author":"Khan","year":"2016","journal-title":"Nat. Rev. Dis. Prim."},{"key":"B36","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1038\/s41576-019-0158-7","article-title":"The biogenesis, biology and characterization of circular RNAs","volume":"20","author":"Kristensen","year":"2019","journal-title":"Nat. Rev. Genet."},{"key":"B37","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/nrc3721","article-title":"Principles and methods of integrative genomic analyses in cancer","volume":"14","author":"Kristensen","year":"2014","journal-title":"Nat. Rev. Cancer"},{"key":"B38","doi-asserted-by":"publisher","first-page":"166442","DOI":"10.1016\/j.bbadis.2022.166442","article-title":"Hydroxyproline stimulates inflammation and reprograms macrophage signaling in a rat kidney stone model","volume":"1868","author":"Kumar","year":"2022","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"B39","doi-asserted-by":"publisher","first-page":"8306736","DOI":"10.1155\/2017\/8306736","article-title":"Integrative analysis of miRNA and mRNA expression profiles in calcium oxalate nephrolithiasis rat model","volume":"2017","author":"Lan","year":"2017","journal-title":"Biomed. Res. Int."},{"key":"B40","doi-asserted-by":"publisher","first-page":"6824","DOI":"10.1002\/jcp.30370","article-title":"Glycine suppresses kidney calcium oxalate crystal depositions via regulating urinary excretions of oxalate and citrate","volume":"236","author":"Lan","year":"2021","journal-title":"J. Cell Physiol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"4663","DOI":"10.1093\/emboj\/cdf476","article-title":"MicroRNA maturation: stepwise processing and subcellular localization","volume":"21","author":"Lee","year":"2002","journal-title":"Embo J."},{"key":"B42","doi-asserted-by":"publisher","first-page":"366","DOI":"10.3390\/nu10030366","article-title":"Vitamin D, hypercalciuria and kidney stones","volume":"10","author":"Letavernier","year":"2018","journal-title":"Nutrients"},{"key":"B43","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1007\/s00240-022-01359-6","article-title":"Inhibitory role of microRNA-484 in kidney stone formation by repressing calcium oxalate crystallization via a VDR\/FoxO1 regulator axis","volume":"50","author":"Li","year":"2022","journal-title":"Urolithiasis."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1038\/s41419-018-1210-9","article-title":"Long noncoding RNA ATB promotes the epithelial-mesenchymal transition by upregulating the miR-200c\/Twist1 axe and predicts poor prognosis in breast cancer","volume":"9","author":"Li","year":"2018","journal-title":"Cell Death Dis."},{"key":"B45","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1186\/s10020-021-00403-2","article-title":"LncRNA-ATB participates in the regulation of calcium oxalate crystal-induced renal injury by sponging the miR-200 family","volume":"27","author":"Li","year":"2021","journal-title":"Mol. Med."},{"key":"B46","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1111\/jcmm.14706","article-title":"LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p\/MCP-1","volume":"24","author":"Li","year":"2020","journal-title":"J. Cell Mol. Med."},{"key":"B47","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s12920-019-0502-y","article-title":"LncRNA-miRNA-mRNA expression variation profile in the urine of calcium oxalate stone patients","volume":"12","author":"Liang","year":"2019","journal-title":"BMC Med. Genomics"},{"key":"B48","doi-asserted-by":"publisher","first-page":"7319","DOI":"10.7150\/thno.44054","article-title":"Sulforaphane elicts dual therapeutic effects on renal inflammatory injury and crystal deposition in calcium oxalate nephrocalcinosis","volume":"10","author":"Liu","year":"2020","journal-title":"Theranostics"},{"key":"B49","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.ebiom.2019.10.059","article-title":"H19 promote calcium oxalate nephrocalcinosis-induced renal tubular epithelial cell injury via a ceRNA pathway","volume":"50","author":"Liu","year":"2019","journal-title":"EBioMedicine"},{"key":"B50","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1007\/s11239-020-02369-0","article-title":"Downregulating LncRNA XIST attenuated contrast-induced nephropathy injury via regulating miR-133a-3p\/ NLRP3 axis","volume":"52","author":"Liu","year":"2021","journal-title":"J. Thromb. Thrombolysis"},{"key":"B51","doi-asserted-by":"publisher","first-page":"4650","DOI":"10.3892\/mmr.2016.5833","article-title":"Analysis of altered microRNA expression profiles in the kidney tissues of ethylene glycol-induced hyperoxaluric rats","volume":"14","author":"Liu","year":"2016","journal-title":"Mol. Med. Rep."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1016\/j.jaci.2017.08.034","article-title":"MicroRNA","volume":"141","author":"Lu","year":"2018","journal-title":"J. Allergy Clin. Immunol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"e1884","DOI":"10.7717\/peerj.1884","article-title":"Integrative microRNA-gene expression network analysis in genetic hypercalciuric stone-forming rat kidney","volume":"4","author":"Lu","year":"2016","journal-title":"PeerJ"},{"key":"B54","doi-asserted-by":"publisher","first-page":"1676152","DOI":"10.1155\/2021\/1676152","article-title":"XIST Inhibition attenuates calcium oxalate nephrocalcinosis-induced renal inflammation and oxidative injury via the miR-223\/NLRP3 pathway","volume":"2021","author":"Lv","year":"2021","journal-title":"Oxid. Med. Cell Longev."},{"key":"B55","doi-asserted-by":"publisher","first-page":"e12525","DOI":"10.1111\/cpr.12525","article-title":"LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF-\u03baB\/NLRP3 inflammasome pathway","volume":"52","author":"Ma","year":"2019","journal-title":"Cell Prolif."},{"key":"B56","doi-asserted-by":"publisher","first-page":"4332","DOI":"10.3390\/ijms22094332","article-title":"MiR-155 as an important regulator of multiple sclerosis pathogenesis. A review","volume":"22","author":"Maciak","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"B57","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1038\/nrd.2016.117","article-title":"Non-coding RNAs as drug targets","volume":"16","author":"Matsui","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"B58","doi-asserted-by":"publisher","first-page":"R17","DOI":"10.1093\/hmg\/ddl046","article-title":"Non-coding RNA","volume":"15","author":"Mattick","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"B59","doi-asserted-by":"publisher","first-page":"101746","DOI":"10.1016\/j.pneurobio.2020.101746","article-title":"Role of circular RNAs in brain development and CNS diseases","volume":"186","author":"Mehta","year":"2020","journal-title":"Prog. Neurobiol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/nature11928","article-title":"Circular RNAs are a large class of animal RNAs with regulatory potency","volume":"495","author":"Memczak","year":"2013","journal-title":"Nature"},{"key":"B61","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1038\/s41576-023-00662-1","article-title":"Non-coding RNAs in disease: from mechanisms to therapeutics","volume":"25","author":"Nemeth","year":"2024","journal-title":"Nat. Rev. Genet."},{"key":"B62","doi-asserted-by":"publisher","first-page":"e2204513","DOI":"10.1002\/advs.202204513","article-title":"A novel protein encoded by exosomal circATG4B induces oxaliplatin resistance in colorectal cancer by promoting autophagy","volume":"9","author":"Pan","year":"2022","journal-title":"Adv. Sci. (Weinh)"},{"key":"B63","doi-asserted-by":"publisher","first-page":"e86","DOI":"10.3909\/riu0459","article-title":"Kidney stones: a global picture of prevalence, incidence, and associated risk factors","volume":"12","author":"Romero","year":"2010","journal-title":"Rev. Urol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"3852","DOI":"10.1073\/pnas.73.11.3852","article-title":"Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures","volume":"73","author":"Sanger","year":"1976","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"B65","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1152\/physrev.00006.2010","article-title":"MicroRNAs in development and disease","volume":"91","author":"Sayed","year":"2011","journal-title":"Physiol. Rev."},{"key":"B66","doi-asserted-by":"publisher","first-page":"7268","DOI":"10.1111\/jcmm.14555","article-title":"Exosomes from miR-20b-3p-overexpressing stromal cells ameliorate calcium oxalate deposition in rat kidney","volume":"23","author":"Shi","year":"2019","journal-title":"J. Cell Mol. Med."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.3390\/genes12081289","article-title":"MiRNAs and cancer: key link in diagnosis and therapy","volume":"12","author":"Shi","year":"2021","journal-title":"Genes (Basel)"},{"key":"B68","doi-asserted-by":"publisher","first-page":"e0150628","DOI":"10.1371\/journal.pone.0150628","article-title":"Integrated analysis of dysregulated ncRNA and mRNA expression profiles in humans exposed to carbon nanotubes","volume":"11","author":"Shvedova","year":"2016","journal-title":"PLoS One"},{"key":"B69","doi-asserted-by":"publisher","first-page":"467","DOI":"10.2174\/1389557515666150324123208","article-title":"MicroRNA therapeutics: the next magic bullet?","volume":"15","author":"Simonson","year":"2015","journal-title":"Mini Rev. Med. Chem."},{"key":"B70","article-title":"EAU guidelines on urolithiasis 2024","author":"Skolarikos","year":"2024","journal-title":"Eur. Assoc. Urology"},{"key":"B71","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1002\/hep.29209","article-title":"H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of epithelial cell adhesion molecule","volume":"66","author":"Song","year":"2017","journal-title":"Hepatology"},{"key":"B72","doi-asserted-by":"publisher","first-page":"10452","DOI":"10.1002\/jcb.28330","article-title":"Long noncoding RNA LINC00339 promotes renal tubular epithelial pyroptosis by regulating the miR-22-3p\/NLRP3 axis in calcium oxalate-induced kidney stone","volume":"120","author":"Song","year":"2019","journal-title":"J. Cell Biochem."},{"key":"B73","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1038\/s41580-020-00315-9","article-title":"Gene regulation by long non-coding RNAs and its biological functions","volume":"22","author":"Statello","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"F202","DOI":"10.1152\/ajprenal.00132.2020","article-title":"MiR-21 promotes calcium oxalate-induced renal tubular cell injury by targeting PPARA","volume":"319","author":"Su","year":"2020","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"B75","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1681\/ASN.2015111271","article-title":"Genome-Wide gene expression profiling of Randall's Plaques in calcium oxalate stone formers","volume":"28","author":"Taguchi","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"673690","DOI":"10.3389\/fimmu.2021.673690","article-title":"Macrophage function in calcium oxalate kidney stone formation: a systematic review of literature","volume":"12","author":"Taguchi","year":"2021","journal-title":"Front. Immunol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"142","DOI":"10.2174\/1566523214666141224095610","article-title":"miR-122 is a unique molecule with great potential in diagnosis, prognosis of liver disease, and therapy both as miRNA mimic and antimir","volume":"15","author":"Thakral","year":"2015","journal-title":"Curr. Gene Ther."},{"key":"B78","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1038\/s41581-020-0320-7","article-title":"Determining the true burden of kidney stone disease","volume":"16","author":"Thongprayoon","year":"2020","journal-title":"Nat. Rev. Nephrol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"194378","DOI":"10.1016\/j.bbagrm.2019.04.005","article-title":"Non-coding RNAs as potential therapeutic targets in breast cancer","volume":"1863","author":"Tomar","year":"2020","journal-title":"Biochim. Biophys. Acta Gene Regul. Mech."},{"key":"B80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4939-6524-3_1","article-title":"MiRNA biogenesis and regulation of diseases: an overview","volume-title":"MicroRNA profiling. Methods in molecular biology","author":"Vishnoi","year":"2017"},{"key":"B81","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s00240-019-01155-9","article-title":"miRNA-34a inhibits cell adhesion by targeting CD44 in human renal epithelial cells: implications for renal stone disease","volume":"48","author":"Wang","year":"","journal-title":"Urolithiasis"},{"key":"B82","doi-asserted-by":"publisher","first-page":"e101306","DOI":"10.1371\/journal.pone.0101306","article-title":"Analysis of altered microRNA expression profiles in proximal renal tubular cells in response to calcium oxalate monohydrate crystal adhesion: implications for kidney stone disease","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"key":"B83","doi-asserted-by":"publisher","first-page":"71","DOI":"10.14336\/AD.2016.0530","article-title":"Long non-coding RNA H19 induces cerebral ischemia reperfusion injury via activation of autophagy","volume":"8","author":"Wang","year":"2017","journal-title":"Aging Dis."},{"key":"B84","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1016\/j.biopha.2018.08.155","article-title":"Suppression of lncRNA-ATB prevents amyloid-\u03b2-induced neurotoxicity in PC12 cells via regulating miR-200\/ZNF217 axis","volume":"108","author":"Wang","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"B85","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/j.molcel.2011.08.018","article-title":"Molecular mechanisms of long noncoding RNAs","volume":"43","author":"Wang","year":"2011","journal-title":"Mol. Cell"},{"key":"B86","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1186\/s12864-023-09478-z","article-title":"Integrated analysis of lncRNA\/circRNA-miRNA-mRNA in the proliferative phase of liver regeneration in mice with liver fibrosis","volume":"24","author":"Wang","year":"2023","journal-title":"BMC Genomics"},{"key":"B87","doi-asserted-by":"publisher","first-page":"375","DOI":"10.3892\/ijmm.2019.4440","article-title":"Overexpression of miR-30c-5p reduces cellular cytotoxicity and inhibits the formation of kidney stones through ATG5","volume":"45","author":"Wang","year":"","journal-title":"Int. J. Mol. Med."},{"key":"B88","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s00240-018-1065-7","article-title":"Analyses of long non-coding RNA and mRNA profiling using RNA sequencing in calcium oxalate monohydrate-stimulated renal tubular epithelial cells","volume":"47","author":"Wang","year":"2019","journal-title":"Urolithiasis"},{"key":"B89","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3892\/ijmm.2021.4982","article-title":"Recent advances on the mechanisms of kidney stone formation (Review)","volume":"48","author":"Wang","year":"2021","journal-title":"Int. J. Mol. Med."},{"key":"B90","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1097\/MNH.0000000000000414","article-title":"Beginnings of nephrolithiasis: insights into the past, present and future of Randall's plaque formation research","volume":"27","author":"Wiener","year":"2018","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"B91","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1126\/science.1238522","article-title":"Molecular biology. A circuitous route to noncoding RNA","volume":"340","author":"Wilusz","year":"2013","journal-title":"Science"},{"key":"B92","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1038\/s41573-021-00219-z","article-title":"Noncoding RNA therapeutics-challenges and potential solutions","volume":"20","author":"Winkle","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"B93","doi-asserted-by":"publisher","first-page":"487","DOI":"10.2215\/CJN.08000520","article-title":"Pathophysiology and treatment of enteric hyperoxaluria","volume":"16","author":"Witting","year":"2021","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"B94","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1007\/s00441-022-03734-6","article-title":"LncRNA LINC01197 inhibited the formation of calcium oxalate-induced kidney stones by regulating miR-516b-5p\/SIRT3\/FOXO1 signaling pathway","volume":"392","author":"Xi","year":"2023","journal-title":"Cell Tissue Res."},{"key":"B95","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s12943-019-1056-5","article-title":"A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1","volume":"18","author":"Xia","year":"2019","journal-title":"Mol. Cancer"},{"key":"B96","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00240-021-01286-y","article-title":"MicroRNA-204 attenuates oxidative stress damage of renal tubular epithelial cells in calcium oxalate kidney-stone formation via MUC4-mediated ERK signaling pathway","volume":"50","author":"Xie","year":"2022","journal-title":"Urolithiasis"},{"key":"B97","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1007\/s00011-022-01643-6","article-title":"Role of miR-155 in inflammatory autoimmune diseases: a comprehensive review","volume":"71","author":"Xu","year":"2022","journal-title":"Inflamm. Res."},{"key":"B98","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s12943-022-01539-3","article-title":"Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p\/PAK6 axis","volume":"21","author":"Xue","year":"2022","journal-title":"Mol. Cancer"},{"key":"B99","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11010-019-03667-9","article-title":"ROS and diseases: role in metabolism and energy supply","volume":"467","author":"Yang","year":"2020","journal-title":"Mol. Cell Biochem."},{"key":"B100","doi-asserted-by":"publisher","first-page":"12011","DOI":"10.7150\/thno.51144","article-title":"AhR activation attenuates calcium oxalate nephrocalcinosis by diminishing M1 macrophage polarization and promoting M2 macrophage polarization","volume":"10","author":"Yang","year":"2020","journal-title":"Theranostics"},{"key":"B101","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s12943-020-01300-8","article-title":"Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer","volume":"20","author":"Yang","year":"2021","journal-title":"Mol. Cancer"},{"key":"B102","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.urology.2022.05.019","article-title":"The preliminary exploration of what role miRNAs derived from urinary exosomes play in kidney stone formation","volume":"166","author":"Yang","year":"2022","journal-title":"Urology"},{"key":"B103","doi-asserted-by":"publisher","first-page":"2516","DOI":"10.1038\/s41388-018-0602-8","article-title":"Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway","volume":"38","author":"Yang","year":"2019","journal-title":"Oncogene"},{"key":"B104","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.7150\/ijbs.57160","article-title":"Theaflavin protects against oxalate calcium-induced kidney oxidative stress injury via upregulation of SIRT1","volume":"17","author":"Ye","year":"2021","journal-title":"Int. J. Biol. Sci."},{"key":"B105","doi-asserted-by":"publisher","first-page":"3011","DOI":"10.1101\/gad.1158803","article-title":"Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs","volume":"17","author":"Yi","year":"2003","journal-title":"Genes Dev."},{"key":"B106","doi-asserted-by":"publisher","first-page":"e202149","DOI":"10.1001\/jamanetworkopen.2020.2149","article-title":"Association of long noncoding RNA biomarkers with clinical immune subtype and prediction of immunotherapy response in patients with cancer","volume":"3","author":"Yu","year":"2020","journal-title":"JAMA Netw. Open"},{"key":"B107","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/bju.13828","article-title":"Prevalence of kidney stones in China: an ultrasonography based cross-sectional study","volume":"120","author":"Zeng","year":"2017","journal-title":"BJU Int."},{"key":"B108","doi-asserted-by":"publisher","first-page":"e6536","DOI":"10.1590\/1414-431X20176536","article-title":"Long non-coding RNA CHCHD4P4 promotes epithelial-mesenchymal transition and inhibits cell proliferation in calcium oxalate-induced kidney damage","volume":"51","author":"Zhang","year":"2017","journal-title":"Braz J. Med. Biol. Res."},{"key":"B109","doi-asserted-by":"publisher","first-page":"20190027","DOI":"10.1515\/jib-2019-0027","article-title":"Non-Coding RNAs and their integrated networks","volume":"16","author":"Zhang","year":"2019","journal-title":"J. Integr. Bioinform"},{"key":"B110","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1038\/s41418-022-00970-9","article-title":"Long noncoding RNA NEAT1 promotes ferroptosis by modulating the miR-362-3p\/MIOX axis as a ceRNA","volume":"29","author":"Zhang","year":"2022","journal-title":"Cell Death Differ."},{"key":"B111","doi-asserted-by":"publisher","first-page":"2883623","DOI":"10.1155\/2023\/2883623","article-title":"Exosomes from miR-23 overexpressing stromal cells suppress M1 macrophage and inhibit calcium oxalate deposition in hyperoxaluria rat model","volume":"2023","author":"Zhang","year":"2023","journal-title":"Biomed. Res. Int."},{"key":"B112","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1007\/s11064-021-03441-8","article-title":"Zinc promotes microglial autophagy through NLRP3 inflammasome inactivation via XIST\/miR-374a-5p axis in spinal cord injury","volume":"47","author":"Zhao","year":"2022","journal-title":"Neurochem. Res."},{"key":"B113","doi-asserted-by":"publisher","first-page":"114228","DOI":"10.1016\/j.bcp.2020.114228","article-title":"LncRNA regulation: new frontiers in epigenetic solutions to drug chemoresistance","volume":"189","author":"Zhou","year":"2021","journal-title":"Biochem. Pharmacol."},{"key":"B114","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1038\/s41419-019-1744-5","article-title":"Roles of circular RNAs in immune regulation and autoimmune diseases","volume":"10","author":"Zhou","year":"2019","journal-title":"Cell Death Dis."},{"key":"B115","doi-asserted-by":"publisher","first-page":"5290","DOI":"10.1111\/jcmm.15185","article-title":"Increased SIX-1 expression promotes breast cancer metastasis by regulating lncATB-miR-200s-ZEB1 axis","volume":"24","author":"Zhu","year":"","journal-title":"J. Cell Mol. Med."},{"key":"B116","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.ebiom.2019.06.004","article-title":"Dietary vinegar prevents kidney stone recurrence via epigenetic regulations","volume":"45","author":"Zhu","year":"","journal-title":"EBioMedicine"},{"key":"B117","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1038\/s42003-023-04649-w","article-title":"Acetate attenuates hyperoxaluria-induced kidney injury by inhibiting macrophage infiltration via the miR-493-3p\/MIF axis","volume":"6","author":"Zhu","year":"2023","journal-title":"Commun. Biol."},{"key":"B118","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1038\/s41419-019-1358-y","article-title":"Loss of the androgen receptor suppresses intrarenal calcium oxalate crystals deposition via altering macrophage recruitment\/M2 polarization with change of the miR-185-5p\/CSF-1 signals","volume":"10","author":"Zhu","year":"","journal-title":"Cell Death Dis."},{"key":"B119","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s00018-024-05408-8","article-title":"miR-148b-5p regulates hypercalciuria and calcium-containing nephrolithiasis","volume":"81","author":"Zhu","year":"2024","journal-title":"Cell Mol. Life Sci."},{"key":"B120","doi-asserted-by":"publisher","first-page":"596363","DOI":"10.3389\/fcell.2020.596363","article-title":"Osteogenic differentiation of renal interstitial fibroblasts promoted by lncRNA MALAT1 may partially contribute to Randall's Plaque formation","volume":"8","author":"Zhu","year":"","journal-title":"Front. Cell Dev. Biol."},{"key":"B121","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.2217\/epi-2021-0212","article-title":"NEAT1 functions as a key mediator of BMP2 to promote osteogenic differentiation of renal interstitial fibroblasts","volume":"13","author":"Zhu","year":"2021","journal-title":"Epigenomics"},{"key":"B122","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3390\/ijms23010090","article-title":"MiR-155: an important regulator of neuroinflammation","volume":"23","author":"Zingale","year":"2021","journal-title":"Int. J. Mol. Sci."}],"container-title":["Frontiers in Cell and Developmental Biology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2024.1457319\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T06:29:53Z","timestamp":1732084193000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2024.1457319\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,20]]},"references-count":122,"alternative-id":["10.3389\/fcell.2024.1457319"],"URL":"https:\/\/doi.org\/10.3389\/fcell.2024.1457319","relation":{},"ISSN":["2296-634X"],"issn-type":[{"type":"electronic","value":"2296-634X"}],"subject":[],"published":{"date-parts":[[2024,11,20]]},"article-number":"1457319"}}