{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T19:32:41Z","timestamp":1772911961596,"version":"3.50.1"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T00:00:00Z","timestamp":1574640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Chem."],"DOI":"10.3389\/fchem.2019.00778","type":"journal-article","created":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T09:32:39Z","timestamp":1574674359000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":27,"title":["A F\u00f6rster Resonance Energy Transfer Switchable Fluorescent Probe With H2S-Activated Second Near-Infrared Emission for Bioimaging"],"prefix":"10.3389","volume":"7","author":[{"given":"Rongchen","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ge","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianli","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianfeng","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunchang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,11,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"11601","DOI":"10.1074\/jbc.M808026200","article-title":"H2S biogenesis by human cystathionine \u03b3-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia","volume":"284","author":"Chiku","year":"2009","journal-title":"Biol. Chem."},{"key":"B2","doi-asserted-by":"publisher","first-page":"5179","DOI":"10.1073\/pnas.1521175113","article-title":"Layer-by-layer assembled fluorescent probes in the second near-infrared window for systemic delivery and detection of ovarian cancer","volume":"113","author":"Dang","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1016\/S0006-291X(02)00422-9","article-title":"Brain hydrogen sulfide is severely decreased in Alzheimer's disease","volume":"293","author":"Eto","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B4","doi-asserted-by":"publisher","first-page":"291","DOI":"10.3389\/fchem.2019.00291","article-title":"Near-infrared aggregation-induced emission-active probe enables in situ and long-term tracking of endogenous b-galactosidase activity","volume":"7","author":"Fu","year":"2019","journal-title":"Front. Chem."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1038\/nm.2995","article-title":"Multifunctional in vivo vascular imaging using near-infrared II fluorescence","volume":"18","author":"Hong","year":"2012","journal-title":"Nat. Med."},{"key":"B6","doi-asserted-by":"publisher","first-page":"14237","DOI":"10.1021\/ja5079656","article-title":"Selective and ratiometric fluorescent trapping and quantification of protein vicinal dithiols and in situ dynamic tracing in living cells","volume":"136","author":"Huang","year":"2014","journal-title":"J. Am. Chem. Soc."},{"key":"B7","doi-asserted-by":"publisher","first-page":"11253","DOI":"10.1021\/acs.analchem.6b04087","article-title":"A novel fluorescein-based fluorescent probe for detecting H2S and its real applications in blood plasma and biological imaging","volume":"88","author":"Jin","year":"2016","journal-title":"Anal. Chem."},{"key":"B8","doi-asserted-by":"publisher","first-page":"485","DOI":"10.3389\/fchem.2018.00485","article-title":"Lighting-up tumor for assisting resection via spraying NIR fluorescent probe of g-glutamyltranspeptidas","volume":"6","author":"Li","year":"2018","journal-title":"Front. Chem."},{"key":"B9","doi-asserted-by":"publisher","first-page":"5429","DOI":"10.1002\/adma.201401356","article-title":"Aggregation-induced emission: the whole is more brilliant than the parts","volume":"26","author":"Mei","year":"2014","journal-title":"Adv. Mater."},{"key":"B10","doi-asserted-by":"publisher","first-page":"11718","DOI":"10.1021\/acs.chemrev.5b00263","article-title":"Aggregation-induced emission: together we shine, united we soar!","volume":"115","author":"Mei","year":"2015","journal-title":"Chem. Rev."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2150","DOI":"10.1039\/C6SC04703C","article-title":"Photoacoustic probes for real-time tracking of endogenous H2S in living mice","volume":"8","author":"Shi","year":"2017","journal-title":"Chem. Sci"},{"key":"B12","doi-asserted-by":"publisher","first-page":"6411","DOI":"10.1021\/acs.nanolett.8b02767","article-title":"Hydrogen sulfide-activatable second near-infrared fluorescent nanoassemblies for targeted photothermal cancer therapy","volume":"18","author":"Shi","year":"2018","journal-title":"Nano Lett."},{"key":"B13","doi-asserted-by":"publisher","first-page":"22457","DOI":"10.1074\/jbc.M109.010868","article-title":"Relative contributions of cystathionine \u03b2-synthase and \u03b3-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions","volume":"284","author":"Singh","year":"2009","journal-title":"Biol. Chem."},{"key":"B14","doi-asserted-by":"publisher","first-page":"3368","DOI":"10.1039\/C4SC01417K","article-title":"A water-soluble boronate-based fluorescent probe for the selective detection of peroxynitrite and imaging in living cells","volume":"5","author":"Sun","year":"2014","journal-title":"Chem. Sci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"12474","DOI":"10.1073\/pnas.1306241110","article-title":"Tumor-derived hydrogen sulfide, produced by cystathionine-\u03b2-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer","volume":"110","author":"Szabo","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B16","doi-asserted-by":"publisher","first-page":"34996","DOI":"10.1039\/C6RA00832A","article-title":"An off\u2013on fluorescent probe for the detection of cysteine \/homocysteine and its imaging in living cells","volume":"6","author":"Tang","year":"2016","journal-title":"RSC Adv."},{"key":"B17","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.biomaterials.2018.01.009","article-title":"Realizing highly chemoselective detection of H2S in vitro and in vivo with fluorescent probes inside core-shell silica nanoparticles","volume":"159","author":"Wang","year":"2018","journal-title":"Biomaterials"},{"key":"B18","doi-asserted-by":"publisher","first-page":"7349","DOI":"10.1002\/anie.201502899","article-title":"Fluorescent in situ targeting probes for rapid imaging of ovarian-cancer-specific g-glutamyltranspeptidase","volume":"54","author":"Wang","year":"2015","journal-title":"Angew. Chem. Int. Ed."},{"key":"B19","doi-asserted-by":"publisher","first-page":"7222","DOI":"10.1039\/C9SC02093D","article-title":"A molecular design strategy toward enzymeactivated probes with near-infrared I and II fluorescence for targeted cancer imaging","volume":"10","author":"Wang","year":"","journal-title":"Chem. Sci."},{"key":"B20","doi-asserted-by":"publisher","first-page":"2785","DOI":"10.1039\/C8SC04854A","article-title":"Activatable near-infrared emission-guided on-demand administration of photodynamic anticancer therapy with a theranostic nanoprobe","volume":"10","author":"Wang","year":"","journal-title":"Chem. Sci."},{"key":"B21","doi-asserted-by":"publisher","first-page":"3626","DOI":"10.1002\/anie.201712528","article-title":"Imaging of colorectal cancers using activatable nanoprobes with second near-infrared window emission","volume":"57","author":"Xu","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"key":"B22","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1002\/anie.201408476","article-title":"Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells","volume":"54","author":"Yuan","year":"2015","journal-title":"Angew. Chem. Int. Ed"},{"key":"B23","doi-asserted-by":"publisher","first-page":"8964","DOI":"10.1021\/acs.analchem.5b02169","article-title":"Dual signaling molecule sensor for rapid detection of hydrogen sulfide based on modified tetraphenylethylene","volume":"87","author":"Zhang","year":"2015","journal-title":"Anal. Chem."},{"key":"B24","doi-asserted-by":"publisher","first-page":"32","DOI":"10.3389\/fchem.2019.00032","article-title":"A near-infrared ratiometric fluorescent probe for highly selective recognition and bioimaging of cysteine","volume":"7","author":"Zhang","year":"2019","journal-title":"Front. Chem."},{"key":"B25","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1039\/C2OB26791H","article-title":"Pyridone fused boron-dipyrromethenes: synthesis and properties","volume":"11","author":"Zhao","year":"2013","journal-title":"Org. Biomol. Chem."},{"key":"B26","doi-asserted-by":"publisher","first-page":"8490","DOI":"10.1021\/jacs.5b03248","article-title":"FRET-switchable self-assembled micellar nanoprobe: ratiometric fluorescent trapping of endogenous H2S generation via fluvastatin-stimulated upregulation","volume":"137","author":"Zhao","year":"2015","journal-title":"J. Am. Chem. Soc."},{"key":"B27","doi-asserted-by":"publisher","first-page":"51194","DOI":"10.1039\/C4RA08191A","article-title":"Aggregation-induced emission block copolymers based on ring-opening metathesis polymerization","volume":"4","author":"Zhao","year":"2014","journal-title":"RSC Adv."},{"key":"B28","doi-asserted-by":"publisher","first-page":"23726","DOI":"10.1039\/c2jm31949g","article-title":"Tetraphenylethene: a versatile AIE building block for the construction of efficient luminescent materials for organic light-emitting diodes","volume":"22","author":"Zhao","year":"2012","journal-title":"J. Mater. Chem."},{"key":"B29","doi-asserted-by":"publisher","first-page":"9838","DOI":"10.1021\/ja504015t","article-title":"Molecular engineering of a TBET-based two-photon fluorescent probe for ratiometric imaging of living cells and tissues","volume":"136","author":"Zhou","year":"2014","journal-title":"J. Am. Chem. Soc."}],"container-title":["Frontiers in Chemistry"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fchem.2019.00778\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T09:32:41Z","timestamp":1574674361000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fchem.2019.00778\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,25]]},"references-count":29,"alternative-id":["10.3389\/fchem.2019.00778"],"URL":"https:\/\/doi.org\/10.3389\/fchem.2019.00778","relation":{},"ISSN":["2296-2646"],"issn-type":[{"value":"2296-2646","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,25]]},"article-number":"778"}}